{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:51:17Z","timestamp":1771476677333,"version":"3.50.1"},"reference-count":74,"publisher":"American Chemical Society (ACS)","issue":"37","license":[{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["CEECIND\/00814 \/2017"],"award-info":[{"award-number":["CEECIND\/00814 \/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["PTDC\/QUI-POL\/28117\/2017"],"award-info":[{"award-number":["PTDC\/QUI-POL\/28117\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/114847\/2016"],"award-info":[{"award-number":["SFRH\/BD\/114847\/2016"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2022,9,21]]},"DOI":"10.1021\/acsami.2c11864","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T13:52:00Z","timestamp":1662126720000},"page":"41779-41789","source":"Crossref","is-referenced-by-count":4,"title":["Hyaluronan Brush-like Copolymers Promote CD44 Declustering in Breast Cancer Cells"],"prefix":"10.1021","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3085-7796","authenticated-orcid":true,"given":"Ana M.","family":"Carvalho","sequence":"first","affiliation":[{"name":"3B\u2019s Research Group, I3Bs \u2013 Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-017Barco, Portugal"},{"name":"ICVS\/3B\u2019s \u2212 PT Government Associate Laboratory, 4710-057Braga\/Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7336-4049","authenticated-orcid":true,"given":"Jesus","family":"Valcarcel","sequence":"additional","affiliation":[{"name":"Grupo de Reciclado y Valorizaci\u00f3n de Materiales Residuales (REVAL), Instituto de Investigaci\u00f3ns Mari\u00f1as (IIM-CSIC), Eduardo Cabello 6, Vigo36208, Galicia, Spain"}]},{"given":"Diana","family":"Soares da Costa","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs \u2013 Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-017Barco, Portugal"},{"name":"ICVS\/3B\u2019s \u2212 PT Government Associate Laboratory, 4710-057Braga\/Guimar\u00e3es, Portugal"}]},{"given":"Marisa","family":"Gomes","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs \u2013 Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-017Barco, Portugal"},{"name":"ICVS\/3B\u2019s \u2212 PT Government Associate Laboratory, 4710-057Braga\/Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1122-4726","authenticated-orcid":true,"given":"Jos\u00e9 Antonio","family":"V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Grupo de Reciclado y Valorizaci\u00f3n de Materiales Residuales (REVAL), Instituto de Investigaci\u00f3ns Mari\u00f1as (IIM-CSIC), Eduardo Cabello 6, Vigo36208, Galicia, Spain"}]},{"given":"Rui L.","family":"Reis","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs \u2013 Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-017Barco, Portugal"},{"name":"ICVS\/3B\u2019s \u2212 PT Government Associate Laboratory, 4710-057Braga\/Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0422-8048","authenticated-orcid":true,"given":"Ramon","family":"Novoa-Carballal","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs \u2013 Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-017Barco, Portugal"},{"name":"ICVS\/3B\u2019s \u2212 PT Government Associate Laboratory, 4710-057Braga\/Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6818-3374","authenticated-orcid":true,"given":"Iva","family":"Pashkuleva","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs \u2013 Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-017Barco, Portugal"},{"name":"ICVS\/3B\u2019s \u2212 PT Government Associate Laboratory, 4710-057Braga\/Guimar\u00e3es, Portugal"}]}],"member":"316","published-online":{"date-parts":[[2022,9,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1391"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00947"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2019.02.002"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-34445-0"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64757-8"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvt085"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-00329-7"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2002.21.5.531"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110069200"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402383111"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2015.04.010"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.10.024"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M500737200"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-1612"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-2491"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.349209"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2317"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.2174\/138920108785161569"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21557"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/103923"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/cm.20544"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1101\/gad.13.1.35"},{"issue":"18","key":"ref23\/cit23","first-page":"5685","volume":"63","author":"Xu X. M.","year":"2003","journal-title":"Cancer Res."},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2004.02.005"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/nm1483"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-04-219204"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0207"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.7150\/thno.50564"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.111.11.1595"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-11-0351"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M806772200"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/D0TB00407C"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.202000122"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111616"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1039\/D0BM00843E"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ma990176p"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.8b01713"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymer.2012.01.027"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58992-7"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/cr050247k"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2015.04.008"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201000267"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc32970k"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-32994-y"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202005212"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1039\/c3cs60097a"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1039\/D0CB00223B"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/b301734f"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201802243"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200902144"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1080\/15321799208018377"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22126376"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.08.042"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/ma00090a021"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/ma012047q"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2020.129837"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2015.05.034"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2008.01.007"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(94)00045-X"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2016.11.036"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1006\/abio.2001.5218"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2020.583826"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.12.221"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2005.01.022"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.06.031"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2010.02.010"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.1.148"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb1201"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.137562"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)61467-5"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.047647"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.8b00561"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1186\/bcr1610"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-14364-2"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c11864","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.2c11864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T08:46:35Z","timestamp":1682412395000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.2c11864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,2]]},"references-count":74,"journal-issue":{"issue":"37","published-print":{"date-parts":[[2022,9,21]]}},"alternative-id":["10.1021\/acsami.2c11864"],"URL":"https:\/\/doi.org\/10.1021\/acsami.2c11864","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,2]]}}}