{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T19:02:36Z","timestamp":1775761356032,"version":"3.50.1"},"reference-count":66,"publisher":"American Chemical Society (ACS)","issue":"48","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100023432","name":"Centro en Red de Medicina Regenerativa y Terapia celular de Castilla y Le?n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023432","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"Agencia Estatal de Investigaci?n","doi-asserted-by":"publisher","award":["PID2022-142682OB-I00"],"award-info":[{"award-number":["PID2022-142682OB-I00"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["ED431C"],"award-info":[{"award-number":["ED431C"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014180","name":"Junta de Castilla y Le?n","doi-asserted-by":"publisher","award":["VA188P23"],"award-info":[{"award-number":["VA188P23"]}],"id":[{"id":"10.13039\/501100014180","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["2022.00764.CEECIND\/CP1718\/CT0020"],"award-info":[{"award-number":["2022.00764.CEECIND\/CP1718\/CT0020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["CEECIND\/02842\/2017\/CP1458\/CT0025"],"award-info":[{"award-number":["CEECIND\/02842\/2017\/CP1458\/CT0025"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["PTDC\/CTM-REF\/0022\/2020"],"award-info":[{"award-number":["PTDC\/CTM-REF\/0022\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Government of Spain","award":["PID2022-137484OB-I00"],"award-info":[{"award-number":["PID2022-137484OB-I00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2024,12,4]]},"DOI":"10.1021\/acsami.4c07285","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T18:42:06Z","timestamp":1732041726000},"page":"66327-66340","source":"Crossref","is-referenced-by-count":5,"title":["Cholesterol Conjugated Elastin-like Recombinamers: Molecular Dynamics Simulations, Conformational Changes, and Bioactivity"],"prefix":"10.1021","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8234-8729","authenticated-orcid":true,"given":"Rui R.","family":"Costa","sequence":"first","affiliation":[{"name":"3B\u2019s Research Group, I3Bs\u2500Research Institute on Biomaterials, Biodegradables, and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-694 Barco, Guimar\u00e3es, Portugal"},{"name":"ICVS\/3B\u2019s, PT Government Associate Laboratory, 4805-694 Braga, Guimar\u00e3es, Portugal"},{"name":"Colloids and Polymers Physics Group, Department of Applied Physics, Faculty of Physics and Institute of Materials (iMATUS) and Institute of Health Research (IDIS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3500-5915","authenticated-orcid":true,"given":"Vicente","family":"Dom\u00ednguez-Arca","sequence":"additional","affiliation":[{"name":"Biosystems and Bioprocess Engineering (Bio2Eng) Group, Institute of Marine Research of Spanish Research Council, IIM-CSIC, 36208 Vigo, Spain"},{"name":"Colloids Physical and Biophysical Chemistry, Bielefeld University, Universit\u00e4tsstr. 25, Bielefeld 33615, Germany"}]},{"given":"Brenda","family":"Velasco","sequence":"additional","affiliation":[{"name":"Colloids and Polymers Physics Group, Department of Applied Physics, Faculty of Physics and Institute of Materials (iMATUS) and Institute of Health Research (IDIS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4295-6129","authenticated-orcid":true,"given":"Rui L.","family":"Reis","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs\u2500Research Institute on Biomaterials, Biodegradables, and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-694 Barco, Guimar\u00e3es, Portugal"},{"name":"ICVS\/3B\u2019s, PT Government Associate Laboratory, 4805-694 Braga, Guimar\u00e3es, Portugal"}]},{"given":"Jos\u00e9 Carlos","family":"Rodr\u00edguez-Cabello","sequence":"additional","affiliation":[{"name":"Bioforge Lab, Group for Advanced Materials and Nanobiotechnology, Biomedical Networking Research Center of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Edificio LUCIA, Universidad de Valladolid, 47011 Valladolid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6818-3374","authenticated-orcid":true,"given":"Iva","family":"Pashkuleva","sequence":"additional","affiliation":[{"name":"3B\u2019s Research Group, I3Bs\u2500Research Institute on Biomaterials, Biodegradables, and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ci\u00eancia e Tecnologia, Zona Industrial da Gandra, 4805-694 Barco, Guimar\u00e3es, Portugal"},{"name":"ICVS\/3B\u2019s, PT Government Associate Laboratory, 4805-694 Braga, Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2903-7857","authenticated-orcid":true,"given":"Pablo","family":"Taboada","sequence":"additional","affiliation":[{"name":"Colloids and Polymers Physics Group, Department of Applied Physics, Faculty of Physics and Institute of Materials (iMATUS) and Institute of Health Research (IDIS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3010-7197","authenticated-orcid":true,"given":"Gerardo","family":"Prieto","sequence":"additional","affiliation":[{"name":"Colloids and Polymers Physics Group, Department of Applied Physics, Faculty of Physics and Institute of Materials (iMATUS) and Institute of Health Research (IDIS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]}],"member":"316","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/bm500658w"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.643110"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2019.100007"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.201900164"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199308191"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201500411"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.836386"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202201646"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/ab10a5"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/bm400167h"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3762\/bjnano.8.80"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/smsc.202300271"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/ncb0107-7"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2014.05.010"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-019-0328-4"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-020-0575-y"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2020.113837"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.06.025"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2018.08.026"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0103116"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2021.111984"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.115858"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.9b00548"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.3c00014"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.01.041"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c12791"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2022.135155"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.3c00124"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/biom12101467"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/bm0509016"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2000.4306"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.26526"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/227718a0"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/C9CP05303D"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2014.02.006"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/bm015630n"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-020-0574-z"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2020.100843"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26020420"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/bi971719v"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/bm201436y"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1500851112"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02252-5"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41566-022-01116-6"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-7388(96)00219-0"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1719065115"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/bi00614a018"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.138539"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2010.09.010"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2020.01.037"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2020.170469"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/bip.23468"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2736(01)00292-9"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b09453"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111813"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202004172"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.04.030"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2019.1582730"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1039\/D2SM00693F"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR02065J"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03819-2"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab1061"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/ct200196m"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-023-00511-7"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac345"},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/978-1-4939-6591-5_2","volume-title":"Liposomes: Methods and Protocols","author":"Zhang H.","year":"2017"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c07285","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsami.4c07285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T09:14:46Z","timestamp":1733303686000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.4c07285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,19]]},"references-count":66,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2024,12,4]]}},"alternative-id":["10.1021\/acsami.4c07285"],"URL":"https:\/\/doi.org\/10.1021\/acsami.4c07285","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,19]]}}}