{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T02:05:37Z","timestamp":1776823537041,"version":"3.51.2"},"reference-count":61,"publisher":"American Chemical Society (ACS)","issue":"13","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["810685"],"award-info":[{"award-number":["810685"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda????o para a Ci??ncia e a Tecnologia","doi-asserted-by":"publisher","award":["CEECINST\/00049\/2018"],"award-info":[{"award-number":["CEECINST\/00049\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda????o para a Ci??ncia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/129312\/2017"],"award-info":[{"award-number":["SFRH\/BD\/129312\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda????o para a Ci??ncia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/00511\/2020"],"award-info":[{"award-number":["UIDB\/00511\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Neurosci."],"published-print":{"date-parts":[[2021,7,7]]},"DOI":"10.1021\/acschemneuro.1c00210","type":"journal-article","created":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T21:28:57Z","timestamp":1623878937000},"page":"2491-2502","source":"Crossref","is-referenced-by-count":16,"title":["Vitamin B12 Inhibits A\u03b2 Fibrillation and Disaggregates Preformed Fibrils in the Presence of Synthetic Neuronal Membranes"],"prefix":"10.1021","volume":"12","author":[{"given":"St\u00e9phanie","family":"Andrade","sequence":"first","affiliation":[{"name":"LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9841-3967","authenticated-orcid":true,"given":"Joana A.","family":"Loureiro","sequence":"additional","affiliation":[{"name":"LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8505-3432","authenticated-orcid":true,"given":"Maria C.","family":"Pereira","sequence":"additional","affiliation":[{"name":"LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]}],"member":"316","published-online":{"date-parts":[[2021,6,16]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Health\nOrganization. Global Action\nPlan on the Public Health Response to Dementia 2017\u20132025, 2017."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21082989"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1177\/1179573520907397"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-019-0609-7"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/trc2.12050"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20092313"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3740461"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00424"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2018.12.006"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/nu9070725"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.2174\/1567205016666190725144629"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2017.03.001"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20141168"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2021.116141"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2020.114689"},{"key":"ref16\/cit16","volume-title":"Handbook of Neurochemistry and Molecular Neurobiology: Neural Lipids","author":"Lim L.","year":"2009"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2020.183476"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01513"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.160696"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2018.04.004"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.720656"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C3TB21483D"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25051195"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2017.05.012"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/bi300839u"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.0c00166"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.7b00006"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2012.03.027"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.104196"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2018.1517736"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c01178"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.10918"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21238916"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-56788-y"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.9b00739"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2006.09.014"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2020.111187"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24010186"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03164-5"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00425"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2016.11.1966"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2019.110615"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/C6CP07774A"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.09.053"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1039\/C7RA03752J"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2019.113"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.bej.2012.12.012"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-010-0529-x"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-01216-5"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2017.02.014"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2012.06.043"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2011.08.015"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2912-14.2015"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2009.12.004"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-021-00704-3"},{"key":"ref56\/cit56","doi-asserted-by":"crossref","unstructured":"Andrade, S., Loureiro, J. A., Coelho, M. A., and do Carmo Pereira, M. (2015) Interaction Studies of Amyloid \u03b2-Peptide with the Natural Compound Resveratrol. Presented at  2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG), pp 1\u20133.","DOI":"10.1109\/ENBENG.2015.7088833"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22020277"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.3390\/biom10060881"},{"key":"ref59\/cit59","doi-asserted-by":"crossref","unstructured":"Chakraborty, R., Dey, S., Paul, S. S., Sil, P., Sengupta, J., and Chattopadhyay, K. (2019) Heme Minimizes Parkinson\u2019s Disease-associated Toxicity by Inducing a Conformational Distortion in the Oligomers of \u03b1-synuclein. In  bioRxiv, pp 1\u201338.","DOI":"10.1101\/629238"},{"key":"ref60\/cit60","volume-title":"Membrane Protein Structure and Function Characterization","author":"Srour B.","year":"2017"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2010.137"}],"container-title":["ACS Chemical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschemneuro.1c00210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T21:49:43Z","timestamp":1682545783000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acschemneuro.1c00210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,16]]},"references-count":61,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2021,7,7]]}},"alternative-id":["10.1021\/acschemneuro.1c00210"],"URL":"https:\/\/doi.org\/10.1021\/acschemneuro.1c00210","relation":{},"ISSN":["1948-7193","1948-7193"],"issn-type":[{"value":"1948-7193","type":"print"},{"value":"1948-7193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,16]]}}}