{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:17:27Z","timestamp":1760645847783},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Crystal Growth & Design"],"published-print":{"date-parts":[[2011,9,7]]},"DOI":"10.1021\/cg200430z","type":"journal-article","created":{"date-parts":[[2011,7,13]],"date-time":"2011-07-13T15:10:14Z","timestamp":1310569814000},"page":"3703-3706","source":"Crossref","is-referenced-by-count":8,"title":["First Crystal Structures of the Antihypertensive Drug Perindopril Erbumine: A Novel Hydrated Form and Polymorphs \u03b1 and \u03b2"],"prefix":"10.1021","volume":"11","author":[{"given":"V\u00e2nia","family":"Andr\u00e9","sequence":"first","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, DEQB, Instituto Superior T\u00e9cnico, Av. Rovisco Pais 1, 1049-001 Lisbon, Portugal"}]},{"given":"Lu\u00eds","family":"Cunha-Silva","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, DEQB, Instituto Superior T\u00e9cnico, Av. Rovisco Pais 1, 1049-001 Lisbon, Portugal"},{"name":"REQUIMTE & Departamento de Qu\u00edmica e Bioqu\u00edmica, Faculdade de Ci\u00eancias, Universidade do Porto, 4169-007 Porto, Portugal"}]},{"given":"M. Teresa","family":"Duarte","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, DEQB, Instituto Superior T\u00e9cnico, Av. Rovisco Pais 1, 1049-001 Lisbon, Portugal"}]},{"given":"Pedro Paulo","family":"Santos","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, DEQB, Instituto Superior T\u00e9cnico, Av. Rovisco Pais 1, 1049-001 Lisbon, Portugal"}]}],"member":"316","published-online":{"date-parts":[[2011,7,22]]},"reference":[{"issue":"5","key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s12039-010-0055-2","volume":"122","author":"Desiraju G. R.","year":"2010","journal-title":"J.Chem. Sci."},{"issue":"12","key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"3989","DOI":"10.1039\/c0ce00237b","volume":"12","author":"Merz K.","year":"2010","journal-title":"CrystEngComm"},{"issue":"3","key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cossms.2009.07.001","volume":"13","author":"Desiraju G. R.","year":"2009","journal-title":"Curr. Opin. Solid State Mater. Sci."},{"issue":"6","key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"2950","DOI":"10.1021\/cg900129f","volume":"9","author":"Schultheiss N.","year":"2009","journal-title":"Cryst. Growth Des."},{"issue":"3","key":"ref5\/cit5","first-page":"317","volume":"9","author":"Peterson M. L.","year":"2006","journal-title":"J. Pharm. Pharmaceut. Sci."},{"issue":"3","key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/jps.20578","volume":"95","author":"Vishweshwar P.","year":"2006","journal-title":"J. Pharm. Sci."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1039\/b504668h","volume":"29","author":"Braga D.","year":"2005","journal-title":"Chem. Commun."},{"issue":"2","key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/ceat.200500397","volume":"29","author":"Karpinski P. H.","year":"2006","journal-title":"Chem. Eng. Technol."},{"issue":"1","key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1021\/cg901010v","volume":"10","author":"Chency M. L.","year":"2010","journal-title":"Cryst. Growth Des."},{"issue":"8","key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1007\/s11095-006-9032-3","volume":"23","author":"McNamara D. P.","year":"2006","journal-title":"Pharm. Res."},{"issue":"1","key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ijpharm.2006.04.018","volume":"320","author":"Trask A. V.","year":"2006","journal-title":"Int. J. Pharm."},{"issue":"5","key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1021\/cg801039j","volume":"9","author":"Good D. J.","year":"2009","journal-title":"Cryst. Growth Des."},{"issue":"12","key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1007\/s10870-009-9591-3","volume":"39","author":"Ma Z. B.","year":"2009","journal-title":"J. Chem. Crystallogr."},{"issue":"9","key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"3931","DOI":"10.1021\/cg1004424","volume":"10","author":"Cherukuvada S.","year":"2010","journal-title":"Cryst. Growth Des."},{"issue":"9","key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1021\/cg9001187","volume":"9","author":"Bethune S. J.","year":"2009","journal-title":"Cryst. Growth Des."},{"issue":"1","key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1021\/cg800587y","volume":"9","author":"Reddy L. S.","year":"2009","journal-title":"Cryst. Growth Des."},{"issue":"3","key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1021\/mp0700108","volume":"4","author":"Remenar J. F.","year":"2007","journal-title":"Mol. Pharmaceutics"},{"issue":"7","key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.addr.2007.05.010","volume":"59","author":"Serajuddin A. T. M.","year":"2007","journal-title":"Adv. Drug Delivery Rev."},{"issue":"1","key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ejpb.2006.12.016","volume":"67","author":"Hickey M. B.","year":"2007","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"2","key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1021\/jm00106a030","volume":"34","author":"Pascard C.","year":"1991","journal-title":"J. Med. Chem."},{"issue":"7","key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/00001721-200010000-00008","volume":"11","author":"Remkova A.","year":"2000","journal-title":"Blood Coagulation Fibrinolysis"},{"issue":"1","key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/09537109877022","volume":"9","author":"Okrucka A.","year":"1998","journal-title":"Platelets"},{"issue":"5","key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/sj.jhh.1002328","volume":"22","author":"Remkova A.","year":"2008","journal-title":"J. Hum. Hypertens."},{"issue":"3","key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/clpt.1990.45","volume":"47","author":"Lecocq B.","year":"1990","journal-title":"Clin. Pharmacol. Therapeut."},{"issue":"1","key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ejmech.2008.03.012","volume":"44","author":"Remko M.","year":"2009","journal-title":"Eur. J. Med. Chem."},{"issue":"5","key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1185\/030079907X182158","volume":"23","author":"Telejko E.","year":"2007","journal-title":"Curr. Med. Res. Opin."},{"key":"ref27\/cit27","unstructured":"Rucman, R.WO2005068490-A1; EP1709066-A1; EP1709066-B1; DE602005009319-E; EP2003142-A1; RU2372353-C2, 2005."},{"key":"ref28\/cit28","unstructured":"Rucman, R.WO2005068425-A1; EP1713771-A1; RU2387641-C2, 2005."},{"key":"ref29\/cit29","unstructured":"Rucman, R.; Zupet, P.WO2007058634-A1; EP1948224-A1; ZA200803889-A, 2007."},{"key":"ref30\/cit30","unstructured":"Rucman, R.; Zupet, P.WO2008150245-A2; WO2008150245-A3; EP2164469-A2; CN101742986-A, 2009."},{"key":"ref31\/cit31","unstructured":"Kumar, A.; Soudagar, S. R.; Mathur, A.; Gunjal, S. T.; Panda, N. B.; Jadhav, D. U.EP1987828-A1, 2008."},{"key":"ref32\/cit32","unstructured":"Kumar, A.; Soudagar, S. R.; Mathur, A.; Panda, N. B.US2008183011-A1; EP1964836-A2; IN200601843-I3; EP1964836-A3, 2008."},{"key":"ref33\/cit33","unstructured":"Churchley, D.; Amberkhane, A., WO2008050185-A2, 2008."},{"key":"ref34\/cit34","unstructured":"Devarakonda, S. N.; Asnani, M.; Bonnareddy, S. R.; Padi, P. R.; Chandramohan, U. K.; Chitre, S. S.; Nalivella, V.; Vasamsetti, S. K.; Minakshi, A.; Reddy, B. S.; Reddy, P. P., WO2007092758-A2; WO2007092758-A3; IN200804031-P4, 2008."},{"key":"ref35\/cit35","unstructured":"Straessler, C.; Lellek, V.; Faessler, R.; Fassler, R.; Strassler, C.; Strossler, C.; Fossler, R.; Christoph, S.; Vit, L.; Roger, F., WO2004113293-A1; NO200600256-A; EP1636185-A1; AU2004249345-A1; BR200411966-A; KR2006035636-A; MX2005013811-A1; CN1812971-A; JP2007507418-W; US2007135512-A1; ZA200600655-A; CN100395235-C; CN101333181-A; NZ544160-A; AU2004249345-B2; AU2004249345-B8; MX268989-B; US7705046-B2; US2010160404-A1, 2005."},{"key":"ref36\/cit36","unstructured":"Ujagare, A.; Kochrekar, D. A.; Sarjekar, P.WO2007017894-A2, 2007."},{"key":"ref37\/cit37","unstructured":"Rucman, R.; Zupet, P.EP1647547-A1, 2006."},{"key":"ref38\/cit38","unstructured":"Ujagare, A.; Kochrekar, D. A.; Sarjekar, P.WO2007017893-A2, 2007."},{"issue":"12","key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"5108","DOI":"10.1021\/cg900495s","volume":"9","author":"Andre V.","year":"2009","journal-title":"Cryst. Growth Des."},{"issue":"1","key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.molstruc.2010.03.067","volume":"973","author":"Andre V.","year":"2010","journal-title":"J. Mol. Struct."},{"issue":"10","key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1039\/b809662g","volume":"32","author":"Braga D.","year":"2008","journal-title":"New J. Chem."},{"issue":"12","key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1039\/b913433f","volume":"11","author":"Braga D.","year":"2009","journal-title":"CrystEngComm"},{"issue":"3","key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1021\/cg800861m","volume":"9","author":"Fabian L.","year":"2009","journal-title":"Cryst. Growth Des."},{"key":"ref44\/cit44","unstructured":"Joshi, N. S.; Bhirud, S. B.; Rao, K. E.US2005250706-A1; WO2005108365-A1; IN200400531-I3; IN220637-B, 2005."},{"key":"ref46\/cit46","unstructured":"Andr\u00e9, V.; Cunha-Silva, L.; Santos, P. P.; Duarte, M. T.PT105315, 2010."},{"issue":"34","key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"6368","DOI":"10.1039\/c0cc01337d","volume":"46","author":"Chow E. H. H.","year":"2010","journal-title":"Chem. Commun."},{"issue":"36","key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"7599","DOI":"10.1039\/c0jm00872a","volume":"20","author":"Friscic T.","year":"2010","journal-title":"J. Mater. Chem."},{"issue":"2","key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1021\/cg800936d","volume":"9","author":"Weyna D. R.","year":"2009","journal-title":"Cryst. Growth Des."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1039\/B512626F","volume":"1","author":"Trask A. V.","year":"2006","journal-title":"Chem. Commun."},{"issue":"3","key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1021\/cg800764n","volume":"9","author":"Friscic T.","year":"2009","journal-title":"Cryst. Growth Des."}],"container-title":["Crystal Growth & Design"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/cg200430z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T16:35:04Z","timestamp":1682267704000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/cg200430z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,22]]},"references-count":50,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9,7]]}},"alternative-id":["10.1021\/cg200430z"],"URL":"https:\/\/doi.org\/10.1021\/cg200430z","relation":{},"ISSN":["1528-7483","1528-7505"],"issn-type":[{"value":"1528-7483","type":"print"},{"value":"1528-7505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,22]]}}}