{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T07:39:34Z","timestamp":1762673974484},"reference-count":26,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T00:00:00Z","timestamp":1416441600000},"content-version":"vor","delay-in-days":129,"URL":"http:\/\/pubs.acs.org\/page\/policy\/authorchoice_ccby_termsofuse.html"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Crystal Growth & Design"],"published-print":{"date-parts":[[2014,8,6]]},"DOI":"10.1021\/cg500150r","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T19:22:01Z","timestamp":1404328921000},"page":"3774-3782","source":"Crossref","is-referenced-by-count":23,"title":["An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form"],"prefix":"10.1021","volume":"14","author":[{"given":"M. F\u00e1tima","family":"Pina","sequence":"first","affiliation":[{"name":"Faculty\rof Pharmacy, University of Coimbra, 3000-214 Coimbra, Portugal"},{"name":"University College London School of Pharmacy, London WC1N 1AX, U.K."},{"name":"iMed-UL,\rFaculty of Pharmacy, University of Lisbon, 1649-0004 Lisbon, Portugal"}]},{"given":"Min","family":"Zhao","sequence":"additional","affiliation":[{"name":"University College London School of Pharmacy, London WC1N 1AX, U.K."}]},{"given":"Jo\u00e3o F.","family":"Pinto","sequence":"additional","affiliation":[{"name":"iMed-UL,\rFaculty of Pharmacy, University of Lisbon, 1649-0004 Lisbon, Portugal"}]},{"given":"Jo\u00e3o J.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Faculty\rof Pharmacy, University of Coimbra, 3000-214 Coimbra, Portugal"}]},{"given":"Christopher S.","family":"Frampton","sequence":"additional","affiliation":[{"name":"SAFC Pharmorphix, A Sigma-Aldrich Company, Cambridge CB4 OWE, U.K."}]},{"given":"Victor","family":"Diaz","sequence":"additional","affiliation":[{"name":"SAFC Pharmorphix, A Sigma-Aldrich Company, Cambridge CB4 OWE, U.K."}]},{"given":"Osama","family":"Suleiman","sequence":"additional","affiliation":[{"name":"SAFC Pharmorphix, A Sigma-Aldrich Company, Cambridge CB4 OWE, U.K."}]},{"given":"L\u00e1szl\u00f3","family":"F\u00e1bi\u00e1n","sequence":"additional","affiliation":[{"name":"School\rof Pharmacy, University of East Anglia, Norwich NR4 7TJ, U.K."}]},{"given":"Duncan Q. M.","family":"Craig","sequence":"additional","affiliation":[{"name":"University College London School of Pharmacy, London WC1N 1AX, U.K."}]}],"member":"316","published-online":{"date-parts":[[2014,7,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1002\/jps.21187","volume":"97","author":"Cui Y.","year":"2008","journal-title":"J. Pharm. Sci."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1021\/cm9600438","volume":"8","author":"Petit S.","year":"1996","journal-title":"Chem. Mater."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1021\/js970250m","volume":"87","author":"Leung S. S.","year":"1998","journal-title":"J. Pharm. Sci."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0928-0987(00)00088-9","volume":"11","author":"Hirayama F.","year":"2000","journal-title":"Eur. J. Pharm. Sci."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1248\/cpb.60.45","volume":"60","author":"Suzuki T.","year":"2012","journal-title":"Chem. Pharm. Bull."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1021\/cg0340749","volume":"3","author":"Te R. L.","year":"2003","journal-title":"Cryst. Growth Des."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.1021\/mp3003573","volume":"9","author":"Pina M. F.","year":"2012","journal-title":"Mol. Pharmaceutics"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1021\/js970449z","volume":"87","author":"Stephenson G. A.","year":"1998","journal-title":"J. Pharm. Sci."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1021\/js9900710","volume":"88","author":"Chen L. R.","year":"1999","journal-title":"J. Pharm. Sci."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.jpba.2005.08.032","volume":"40","author":"Vogt F. G.","year":"2006","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","DOI":"10.1002\/3527607889","volume-title":"Polymorphism in the Pharmaceutical Industry","author":"Hilfiker R.","year":"2006"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1021\/js9900250","volume":"88","author":"Sheng J.","year":"1999","journal-title":"J. Pharm. Sci."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1021\/jp012836+","volume":"106","author":"Willart J. F.","year":"2002","journal-title":"J. Phys. Chem. B"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tca.2011.03.034","volume":"520","author":"Vyazovkin S.","year":"2011","journal-title":"Thermochim. Acta"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/jps.20559","volume":"95","author":"Khawam A.","year":"2006","journal-title":"J. Pharm. Sci."},{"key":"ref16\/cit16","unstructured":"Barnes, R. D.; Wood-Kaczmar, M. W.; Curzons, A. D.; Lynch, I. R.; Richardson, J. E.; Buxton, P. C.Anti-depressant crystalline paroxetine hydrochloride hemihydrate. Patent US4,721,723, 1988."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1107\/S0108270198013444","volume":"55","author":"Ibers J. A.","year":"1999","journal-title":"Acta Crystallogr., Sect. C: Cryst. Struct. Commun."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s10973-011-2051-2","volume":"108","author":"Bruni G.","year":"2012","journal-title":"J. Therm. Anal. Calorim."},{"key":"ref19\/cit19","unstructured":"Howard, J. A. K.; Pattison, P.; Chetina, O.Private communication to the Cambridge Crystallographic Data Centre, 2003."},{"key":"ref20\/cit20","volume-title":"TOPAS Academic User Manual","author":"Coelho A.","year":"2007"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1107\/S0021889806042117","volume":"39","author":"David W. I. F.","year":"2006","journal-title":"J. Appl. Crystallogr."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1107\/S0021889804014876","volume":"37","author":"Boultif A.","year":"2004","journal-title":"J. Appl. Crystallogr."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0040-6031(99)00253-1","volume":"340","author":"Vyazovkin S.","year":"1999","journal-title":"Thermochim. Acta"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1246\/bcsj.38.1881","volume":"38","author":"Ozawa T.","year":"1965","journal-title":"Bull. Chem. Soc. Jpn."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/pol.1966.110040504","volume":"4","author":"Flynn J. H.","year":"1966","journal-title":"J. Polym. Sci., Part B: Polym. Lett."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.1002\/jps.23257","volume":"101","author":"Shimanovich R.","year":"2012","journal-title":"J. Pharm. Sci."}],"container-title":["Crystal Growth & Design"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/cg500150r","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T06:22:42Z","timestamp":1682576562000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/cg500150r"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,14]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8,6]]}},"alternative-id":["10.1021\/cg500150r"],"URL":"https:\/\/doi.org\/10.1021\/cg500150r","relation":{},"ISSN":["1528-7483","1528-7505"],"issn-type":[{"value":"1528-7483","type":"print"},{"value":"1528-7505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,14]]}}}