{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:48:37Z","timestamp":1778086117069,"version":"3.51.4"},"reference-count":287,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T00:00:00Z","timestamp":1424649600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/pubs.acs.org\/page\/policy\/authorchoice_ccby_termsofuse.html"}],"funder":[{"DOI":"10.13039\/100004431","name":"European Commission Directorate-General for Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004431","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Rev."],"published-print":{"date-parts":[[2015,3,11]]},"DOI":"10.1021\/cr500399p","type":"journal-article","created":{"date-parts":[[2015,2,20]],"date-time":"2015-02-20T19:01:21Z","timestamp":1424458881000},"page":"2174-2195","source":"Crossref","is-referenced-by-count":1069,"title":["Advances in Chemical Protein Modification"],"prefix":"10.1021","volume":"115","author":[{"given":"Omar","family":"Boutureira","sequence":"first","affiliation":[{"name":"Departament\rde Qu\u00edmica Anal\u00edtica i Qu\u00edmica Org\u00e0nica, Universitat Rovira i Virgili, C\/Marcel\u00b7l\u00ed Domingo s\/n, 43007 Tarragona, Spain"}]},{"given":"Gon\u00e7alo J. L.","family":"Bernardes","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, United Kingdom"},{"name":"Instituto\rde Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]}],"member":"316","published-online":{"date-parts":[[2015,2,20]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1038\/nchembio.720","volume":"7","author":"Stephanopoulos N.","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"7342","DOI":"10.1002\/anie.200501023","volume":"44","author":"Walsh C. T.","year":"2005","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1021\/cb200445w","volume":"7","author":"Kee J.-M.","year":"2011","journal-title":"ACS Chem. Biol."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","DOI":"10.1002\/9783527630516.ch3","volume-title":"Chemical Protein Modification","author":"Bernardes G. J. L.","year":"2010"},{"key":"ref5\/cit5a","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1002\/cbic.201402154","volume":"15","author":"Sun S. B.","year":"2014","journal-title":"ChemBioChem."},{"key":"ref5\/cit5b","doi-asserted-by":"crossref","first-page":"14323","DOI":"10.1021\/ja504390x","volume":"136","author":"Pelegri-O\u2019Day E. M.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref5\/cit5c","doi-asserted-by":"crossref","first-page":"3796","DOI":"10.1002\/anie.201307628","volume":"53","author":"Chari R. V. J.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref5\/cit5d","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cbpa.2014.09.018","volume":"22","author":"Schumacher D.","year":"2014","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref6\/cit6a","doi-asserted-by":"crossref","first-page":"5684","DOI":"10.1039\/c2ob25149c","volume":"10","author":"Siman P.","year":"2012","journal-title":"Org. Biomol. Chem."},{"key":"ref6\/cit6b","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1039\/B700141J","volume":"38","author":"Kent S. B. H.","year":"2009","journal-title":"Chem. Soc. Rev."},{"key":"ref6\/cit6c","doi-asserted-by":"crossref","first-page":"10030","DOI":"10.1002\/anie.200801313","volume":"47","author":"Hackenberger C. P. R.","year":"2008","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.chembiol.2010.02.008","volume":"17","author":"Basl\u00e9 E.","year":"2010","journal-title":"Chem. Biol."},{"key":"ref8\/cit8a","doi-asserted-by":"crossref","first-page":"5930","DOI":"10.1002\/anie.201208741","volume":"52","author":"Tasdelen M. A.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref8\/cit8b","doi-asserted-by":"crossref","first-page":"9309","DOI":"10.1039\/c2ob26409a","volume":"10","author":"Palomo J. M.","year":"2012","journal-title":"Org. Biomol. Chem."},{"key":"ref8\/cit8c","doi-asserted-by":"crossref","first-page":"8806","DOI":"10.1002\/anie.201008102","volume":"50","author":"van Berkel S. S.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref8\/cit8d","doi-asserted-by":"crossref","first-page":"8794","DOI":"10.1002\/anie.201101019","volume":"50","author":"Lallana E.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref9\/cit9a","doi-asserted-by":"crossref","first-page":"4868","DOI":"10.1021\/cr400290x","volume":"114","author":"Villalonga M. L.","year":"2014","journal-title":"Chem. Rev."},{"key":"ref9\/cit9b","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.chembiol.2014.01.001","volume":"21","author":"Wang L.-X.","year":"2014","journal-title":"Chem. Biol."},{"key":"ref9\/cit9c","doi-asserted-by":"crossref","first-page":"4259","DOI":"10.1021\/cr200113w","volume":"111","author":"Schmaltz R. M.","year":"2011","journal-title":"Chem. Rev."},{"key":"ref9\/cit9d","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1021\/cr078291i","volume":"109","author":"Gamblin D. P.","year":"2009","journal-title":"Chem. Rev."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"10727","DOI":"10.1021\/jo502136n","volume":"79","author":"Nischan N.","year":"2014","journal-title":"J. Org. Chem."},{"key":"ref11\/cit11a","doi-asserted-by":"crossref","first-page":"6513","DOI":"10.1021\/ja408069v","volume":"136","author":"Matyjaszewski K.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref11\/cit11b","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1039\/C3PY01193C","volume":"5","author":"Wallat J. D.","year":"2014","journal-title":"Polym. Chem."},{"key":"ref12\/cit12a","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1021\/bc500028d","volume":"25","author":"King M.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref12\/cit12b","doi-asserted-by":"crossref","first-page":"4764","DOI":"10.1021\/cr400355w","volume":"114","author":"Lang K.","year":"2014","journal-title":"Chem. Rev."},{"key":"ref12\/cit12c","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1021\/cb400828a","volume":"9","author":"Patterson D. M.","year":"2014","journal-title":"ACS Chem. Biol."},{"key":"ref12\/cit12d","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1021\/cb4009292","volume":"9","author":"Lang K.","year":"2014","journal-title":"ACS Chem. Biol."},{"key":"ref12\/cit12e","doi-asserted-by":"crossref","first-page":"4088","DOI":"10.1002\/anie.201207089","volume":"52","author":"Takaoka Y.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref12\/cit12f","doi-asserted-by":"crossref","first-page":"6439","DOI":"10.1039\/c3ob41329b","volume":"11","author":"Debets M. F.","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"ref12\/cit12g","doi-asserted-by":"crossref","first-page":"11007","DOI":"10.1039\/c3cc44272a","volume":"49","author":"Ramil C. P.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref12\/cit12h","doi-asserted-by":"crossref","first-page":"6974","DOI":"10.1002\/anie.200900942","volume":"48","author":"Sletten E. M.","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref12\/cit12i","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.cbpa.2014.07.002","volume":"21","author":"Shih H.-W.","year":"2014","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref12\/cit12j","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.chembiol.2014.09.002","volume":"21","author":"McKay C. S.","year":"2014","journal-title":"Chem. Biol."},{"key":"ref12\/cit12k","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.1038\/ncomms5740","volume":"5","author":"Spicer C. D.","year":"2014","journal-title":"Nat. Commun."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/asia.200800427","volume":"4","author":"Chalker J. M.","year":"2009","journal-title":"Chem.\u2014Asian J."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1021\/ja412594d","volume":"136","author":"Hemantha H. P.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref15\/cit15a","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1021\/bc500111t","volume":"25","author":"Massa S.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref15\/cit15b","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1039\/B920576D","volume":"8","author":"Morales-Sanfrutos J.","year":"2010","journal-title":"Org. Biomol. Chem."},{"key":"ref15\/cit15c","doi-asserted-by":"crossref","first-page":"4039","DOI":"10.1021\/jo100324p","volume":"75","author":"Morales-Sanfrutos J.","year":"2010","journal-title":"J. Org. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"10585","DOI":"10.1002\/anie.201405702","volume":"53","author":"Cal P. M. S. D.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1021\/bc400245v","volume":"25","author":"Badescu G.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref18\/cit18a","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1039\/C3OB42194E","volume":"12","author":"Bailey J. J.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref18\/cit18b","doi-asserted-by":"crossref","first-page":"8220","DOI":"10.1039\/c3cs60153f","volume":"42","author":"Wurm F. R.","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"ref18\/cit18c","doi-asserted-by":"crossref","first-page":"9119","DOI":"10.1039\/c0cc03420g","volume":"46","author":"Patel M. K.","year":"2010","journal-title":"Chem. Commun."},{"key":"ref18\/cit18d","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1039\/C3CC48263D","volume":"50","author":"Liu Z.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"11783","DOI":"10.1002\/anie.201405924","volume":"53","author":"Asano S.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1039\/c3sc50862e","volume":"4","author":"Adamo R.","year":"2013","journal-title":"Chem. Sci."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/cbic.201300785","volume":"15","author":"Crotti S.","year":"2014","journal-title":"ChemBioChem"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1021\/bc200556n","volume":"23","author":"Chen X.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/cmdc.201300385","volume":"9","author":"del Castillo T.","year":"2014","journal-title":"ChemMedChem"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.cbpa.2010.12.002","volume":"15","author":"D\u00edaz-Rodr\u00edguez A.","year":"2011","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1039\/C4SC01768D","volume":"6","author":"McGrath N. A.","year":"2015","journal-title":"Chem. Sci."},{"key":"ref26\/cit26a","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1021\/bm300807b","volume":"13","author":"Kramer J. R.","year":"2012","journal-title":"Biomacromolecules"},{"key":"ref26\/cit26b","doi-asserted-by":"crossref","first-page":"5144","DOI":"10.1039\/c3cc42214c","volume":"49","author":"Kramer J. R.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1055\/s-0030-1261192","volume":"2011","author":"Tanaka K.","year":"2011","journal-title":"Synlett"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"14527","DOI":"10.1073\/pnas.0303574101","volume":"101","author":"Robinson M. A.","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"56455","DOI":"10.1039\/C4RA11131A","volume":"4","author":"Bavaro T.","year":"2014","journal-title":"RSC Adv."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"10299","DOI":"10.1021\/ja303436y","volume":"134","author":"Cal P. M. S. D.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1039\/C3CC47534D","volume":"50","author":"Cal P. M. S. D.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"3908","DOI":"10.1021\/ol5016509","volume":"16","author":"Diethelm S.","year":"2014","journal-title":"Org. Lett."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1021\/ja208009r","volume":"134","author":"Chan A. O.-Y.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref34\/cit34a","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1002\/cbic.201300453","volume":"14","author":"Kulkarni C.","year":"2013","journal-title":"ChemBioChem"},{"key":"ref34\/cit34b","doi-asserted-by":"crossref","first-page":"15139","DOI":"10.1021\/ja2055098","volume":"133","author":"Wagner A. M.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref35\/cit35a","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1021\/ja046239n","volume":"127","author":"Schlick T. L.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref35\/cit35b","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1021\/ja031790q","volume":"126","author":"Hooker J. M.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1021\/bc300410p","volume":"23","author":"Gavrilyuk J.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"9528","DOI":"10.1039\/C4OB01873G","volume":"12","author":"Zhang J.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1021\/bc400168u","volume":"24","author":"Chen S.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref39\/cit39a","doi-asserted-by":"crossref","first-page":"9108","DOI":"10.1002\/anie.201102539","volume":"50","author":"Lorenzi M.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref39\/cit39b","doi-asserted-by":"crossref","first-page":"7639","DOI":"10.1021\/ja710927q","volume":"130","author":"McFarland J. M.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref39\/cit39c","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1021\/bc700231v","volume":"19","author":"Romanini D. W.","year":"2008","journal-title":"Bioconjugate Chem."},{"key":"ref39\/cit39d","doi-asserted-by":"crossref","first-page":"15942","DOI":"10.1021\/ja0439017","volume":"126","author":"Joshi N. S.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1021\/bc4000542","volume":"24","author":"Mileo E.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.bmcl.2008.12.071","volume":"19","author":"Guo H.-M.","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1021\/ja909062q","volume":"132","author":"Ban H.","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"ref43\/cit43a","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1039\/c3sc51694f","volume":"4","author":"Hu Q.-Y.","year":"2013","journal-title":"Chem. Sci."},{"key":"ref43\/cit43b","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.1039\/C4SC01361A","volume":"5","author":"Adamo R.","year":"2014","journal-title":"Chem. Sci."},{"key":"ref43\/cit43c","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1021\/bc500438h","volume":"25","author":"Nilo A.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1021\/bc4001799","volume":"24","author":"Bauer D. M.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1021\/ar200056q","volume":"44","author":"Chalker J. M.","year":"2011","journal-title":"Acc. Chem. Res."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1002\/anie.201106658","volume":"51","author":"Boutureira O.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref47\/cit47a","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1039\/c1sc00185j","volume":"2","author":"Chalker J. M.","year":"2011","journal-title":"Chem. Sci."},{"key":"ref47\/cit47b","doi-asserted-by":"crossref","first-page":"5052","DOI":"10.1021\/ja800800p","volume":"130","author":"Bernardes G. J. L.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref47\/cit47c","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1002\/anie.200704381","volume":"47","author":"Bernardes G. J. L.","year":"2008","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1021\/ol403416w","volume":"16","author":"Haj-Yahya N.","year":"2014","journal-title":"Org. Lett."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"10010","DOI":"10.1039\/c1cc13524d","volume":"47","author":"Boutureira O.","year":"2011","journal-title":"Chem. Commun."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1021\/bc3005232","volume":"24","author":"Kunstelj M.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1002\/anie.201006327","volume":"50","author":"Grayson E. J.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1002\/anie.201106432","volume":"51","author":"Chalker J. M.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1039\/c0sc00265h","author":"Fern\u00e1ndez-Gonz\u00e1lez M.","year":"2010","journal-title":"Chem. Sci."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1021\/ja411522f","volume":"136","author":"Aydillo C.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/nbt.1480","volume":"26","author":"Junutula J. R.","year":"2008","journal-title":"Nat. Biotechnol."},{"key":"ref56\/cit56a","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1039\/C2SC21107F","volume":"4","author":"Steiner M.","year":"2013","journal-title":"Chem. Sci."},{"key":"ref56\/cit56b","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1002\/anie.201106527","volume":"51","author":"Bernardes G. J. L.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref56\/cit56c","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1158\/0008-5472.CAN-13-2990","volume":"74","author":"Perrino E.","year":"2014","journal-title":"Cancer Res."},{"key":"ref56\/cit56d","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1038\/nprot.2013.121","volume":"8","author":"Bernardes G. J. L.","year":"2013","journal-title":"Nat. Protoc."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"5887","DOI":"10.1021\/ja211589m","volume":"134","author":"Casi G.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1039\/C3OB41241E","volume":"12","author":"Yuan Y.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref59\/cit59a","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1039\/c3ob40239h","volume":"11","author":"Nathani R. I.","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"ref59\/cit59b","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1021\/ja908610s","volume":"132","author":"Smith M. E. B.","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/cbic.201100603","volume":"13","author":"Moody P.","year":"2012","journal-title":"ChemBioChem"},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"7139","DOI":"10.1039\/C4CC02107J","volume":"50","author":"Marculescu C.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref62\/cit62a","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/nbt.2968","volume":"32","author":"Lyon R. P.","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"ref62\/cit62b","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1021\/bc500357n","volume":"25","author":"Tumey L. N.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref62\/cit62c","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1021\/bc5005262","volume":"26","author":"Fontaine S. D.","year":"2015","journal-title":"Bioconjugate Chem."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"8781","DOI":"10.1039\/c1cc12807h","volume":"47","author":"Chudasama V.","year":"2011","journal-title":"Chem. Commun."},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC08515A"},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1002\/cbic.201200231","volume":"13","author":"Nathani R.","year":"2012","journal-title":"ChemBioChem"},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1039\/c3sc51333e","volume":"4","author":"Nathani R. I.","year":"2013","journal-title":"Chem. Sci."},{"key":"ref67\/cit67","doi-asserted-by":"crossref","first-page":"3839","DOI":"10.1002\/chem.200800669","volume":"15","author":"Shiu H.-Y.","year":"2009","journal-title":"Chem.\u2014Eur. J."},{"key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"4375","DOI":"10.1039\/c3cc48376b","volume":"50","author":"Shiu H.-Y.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1021\/bc400469d","volume":"25","author":"Koniev O.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref70\/cit70","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1039\/C3SC51691A","volume":"5","author":"Arumugam S.","year":"2014","journal-title":"Chem. Sci."},{"key":"ref71\/cit71","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1021\/ol301370s","volume":"14","author":"Zhang D.","year":"2012","journal-title":"Org. Lett."},{"key":"ref72\/cit72","doi-asserted-by":"crossref","first-page":"12592","DOI":"10.1002\/anie.201306241","volume":"52","author":"Toda N.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref73\/cit73","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1021\/bc500276m","volume":"25","author":"Patterson J. T.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref74\/cit74","doi-asserted-by":"crossref","first-page":"7491","DOI":"10.1002\/anie.201403121","volume":"53","author":"Abbas A.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref75\/cit75","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1021\/bc015519e","volume":"12","author":"Lutolf M. P.","year":"2001","journal-title":"Bioconjugate Chem."},{"key":"ref76\/cit76","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1002\/asia.201402095","volume":"9","author":"Ma F.-H.","year":"2014","journal-title":"Chem.\u2014Asian J."},{"key":"ref77\/cit77","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1039\/C4CC00053F","volume":"50","author":"Moody P.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref78\/cit78","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/nbt.2108","volume":"30","author":"Shen B.-Q.","year":"2012","journal-title":"Nat. Biotechnol."},{"key":"ref79\/cit79a","doi-asserted-by":"crossref","first-page":"6916","DOI":"10.1021\/ja300500a","volume":"134","author":"Valkevich E. M.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref79\/cit79b","doi-asserted-by":"crossref","first-page":"9611","DOI":"10.1002\/anie.201103754","volume":"50","author":"Li F.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref80\/cit80","doi-asserted-by":"crossref","first-page":"11086","DOI":"10.1039\/c1cc14402b","volume":"47","author":"Conte M. L.","year":"2011","journal-title":"Chem. Commun."},{"key":"ref81\/cit81a","doi-asserted-by":"crossref","first-page":"5267","DOI":"10.1039\/C3CC47496H","volume":"50","author":"Chen S.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref81\/cit81b","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1002\/anie.201309459","volume":"53","author":"Chen S.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref81\/cit81c","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1021\/bc300184m","volume":"23","author":"Angelini A.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref81\/cit81d","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cbpa.2011.03.009","volume":"15","author":"Angelini A.","year":"2011","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref81\/cit81e","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/nchembio.184","volume":"5","author":"Heinis C.","year":"2009","journal-title":"Nat. Chem. Biol."},{"key":"ref82\/cit82","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1039\/C4CC00811A","volume":"50","author":"Fukunaga K.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref83\/cit83","doi-asserted-by":"crossref","first-page":"5880","DOI":"10.1021\/ja501861m","volume":"136","author":"Bellotto S.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref84\/cit84a","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1039\/C3OB42168F","volume":"12","author":"Zou Y.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref84\/cit84b","doi-asserted-by":"crossref","first-page":"3652","DOI":"10.1021\/ol501609y","volume":"16","author":"Zhang C.","year":"2014","journal-title":"Org. Lett."},{"key":"ref84\/cit84c","doi-asserted-by":"crossref","first-page":"14001","DOI":"10.1002\/anie.201306430","volume":"52","author":"Zhang C.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref85\/cit85","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1126\/science.281.5374.269","volume":"281","author":"Griffin B. A.","year":"1998","journal-title":"Science"},{"key":"ref86\/cit86","doi-asserted-by":"crossref","first-page":"6880","DOI":"10.1002\/anie.201302181","volume":"52","author":"Kim T. H.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref87\/cit87a","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1021\/bc400102w","volume":"24","author":"Rashidian M.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref87\/cit87b","doi-asserted-by":"crossref","first-page":"16388","DOI":"10.1021\/ja403813b","volume":"135","author":"Rashidian M.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref88\/cit88","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1021\/ic401612z","volume":"53","author":"Uchinomiya S.","year":"2014","journal-title":"Inorg. Chem."},{"key":"ref89\/cit89a","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1021\/cb500453a","volume":"9","author":"Chen X.-H.","year":"2014","journal-title":"ACS Chem. Biol."},{"key":"ref89\/cit89b","doi-asserted-by":"crossref","first-page":"8411","DOI":"10.1021\/ja502851h","volume":"136","author":"Furman J. L.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref89\/cit89c","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1021\/bc500134w","volume":"25","author":"Lu Y.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref89\/cit89d","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1002\/anie.201308794","volume":"53","author":"Xiang Z.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref89\/cit89e","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1021\/bi500205x","volume":"53","author":"Masuya T.","year":"2014","journal-title":"Biochemistry"},{"key":"ref89\/cit89f","doi-asserted-by":"crossref","first-page":"12252","DOI":"10.1021\/ja4043214","volume":"135","author":"Hayashi T.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref89\/cit89g","doi-asserted-by":"crossref","first-page":"5022","DOI":"10.1039\/c3cc41979g","volume":"49","author":"Uchinomiya S.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref89\/cit89h","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1021\/ja209641t","volume":"134","author":"Tamura T.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref89\/cit89i","doi-asserted-by":"crossref","first-page":"3961","DOI":"10.1021\/ja2108855","volume":"134","author":"Fujishima S.-h.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref89\/cit89j","doi-asserted-by":"crossref","first-page":"12220","DOI":"10.1021\/ja204422r","volume":"133","author":"Wang H.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref89\/cit89k","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/nchembio.157","volume":"5","author":"Tsukiji S.","year":"2009","journal-title":"Nat. Chem. Biol."},{"key":"ref89\/cit89l","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1021\/ja075684q","volume":"130","author":"Koshi Y.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref90\/cit90","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1039\/C3MD00356F","volume":"5","author":"Lodge J. M.","year":"2014","journal-title":"MedChemComm"},{"key":"ref91\/cit91","doi-asserted-by":"crossref","first-page":"8681","DOI":"10.1002\/anie.201303831","volume":"52","author":"Sato S.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref92\/cit92","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.addr.2007.06.014","volume":"60","author":"Brocchini S.","year":"2008","journal-title":"Adv. Drug Delivery Rev."},{"key":"ref93\/cit93a","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1021\/bc500148x","volume":"25","author":"Badescu G.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref93\/cit93b","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1039\/C3CC47003B","volume":"50","author":"Wang T.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref93\/cit93c","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/chem.201403965","volume":"21","author":"Wang T.","year":"2015","journal-title":"Chem.\u2014Eur. J."},{"key":"ref94\/cit94","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1021\/bc200530x","volume":"23","author":"Cong Y.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref95\/cit95a","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1021\/bc5000324","volume":"25","author":"Bryden F.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref95\/cit95b","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1021\/ja210335f","volume":"134","author":"Jones M. W.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref96\/cit96a","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.1039\/c2cc30259d","volume":"48","author":"Jones M. W.","year":"2012","journal-title":"Chem. Commun."},{"key":"ref96\/cit96b","doi-asserted-by":"crossref","first-page":"7261","DOI":"10.1039\/C4OB01550A","volume":"12","author":"Schumacher F. F.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref97\/cit97","doi-asserted-by":"crossref","first-page":"8187","DOI":"10.1039\/c3cc45220d","volume":"49","author":"Casta\u00f1eda L.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref98\/cit98","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1021\/bc5002467","volume":"25","author":"Hull E. A.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref99\/cit99a","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1021\/bc300472e","volume":"24","author":"Dhal P. K.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref99\/cit99b","doi-asserted-by":"crossref","first-page":"7100","DOI":"10.1039\/c2cc32412a","volume":"48","author":"Zuberb\u00fchler K.","year":"2012","journal-title":"Chem. Commun."},{"key":"ref99\/cit99c","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nmeth.1305","volume":"6","author":"Zeng Y.","year":"2009","journal-title":"Nat. Methods"},{"key":"ref99\/cit99d","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/nbt827","volume":"21","author":"Zhang H.","year":"2003","journal-title":"Nat. Biotechnol."},{"key":"ref100\/cit100","doi-asserted-by":"crossref","first-page":"17223","DOI":"10.1021\/ja408868a","volume":"135","author":"Witus L. S.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref101\/cit101","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/nchembio878","volume":"3","author":"Carrico I. S.","year":"2007","journal-title":"Nat. Chem. Biol."},{"key":"ref102\/cit102","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1021\/bc300516f","volume":"24","author":"El-Mahdi O.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref103\/cit103a","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1021\/bc500061s","volume":"25","author":"Smith E. L.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref103\/cit103b","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.1002\/anie.201108130","volume":"51","author":"Hudak J. E.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref103\/cit103c","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1021\/cb300187t","volume":"7","author":"Ng S.","year":"2012","journal-title":"ACS Chem. Biol."},{"key":"ref103\/cit103d","doi-asserted-by":"crossref","first-page":"11863","DOI":"10.1002\/anie.201408103","volume":"53","author":"Kularatne S. A.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref104\/cit104a","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1021\/bm500174p","volume":"15","author":"Lu Y.","year":"2014","journal-title":"Biomacromolecules"},{"key":"ref104\/cit104b","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1021\/bc400435u","volume":"25","author":"Zhou Z.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref105\/cit105","doi-asserted-by":"crossref","first-page":"8149","DOI":"10.1021\/ja5023909","volume":"136","author":"Kitov P. I.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref106\/cit106","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1073\/pnas.1213186110","volume":"110","author":"Agarwal P.","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref107\/cit107","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1021\/bc400042a","volume":"24","author":"Agarwal P.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref108\/cit108","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1021\/bc500189z","volume":"25","author":"Drake P. M.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref109\/cit109","doi-asserted-by":"crossref","first-page":"11079","DOI":"10.1039\/c2cc35738k","volume":"48","author":"Han M.-J.","year":"2012","journal-title":"Chem. Commun."},{"key":"ref110\/cit110","doi-asserted-by":"crossref","first-page":"11188","DOI":"10.1039\/c3cc45961f","volume":"49","author":"Lum K. M.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref111\/cit111","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1002\/cbic.201100206","volume":"12","author":"van Hest J. C. M.","year":"2011","journal-title":"ChemBioChem"},{"key":"ref112\/cit112a","doi-asserted-by":"crossref","first-page":"5060","DOI":"10.1021\/ol402404n","volume":"15","author":"Ahad A. M.","year":"2013","journal-title":"Org. Lett."},{"key":"ref112\/cit112b","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1002\/cbic.201100125","volume":"12","author":"Bernardes G. J. L.","year":"2011","journal-title":"ChemBioChem"},{"key":"ref113\/cit113","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1039\/c0sc00324g","author":"Serwa R.","year":"2010","journal-title":"Chem. Sci."},{"key":"ref114\/cit114","doi-asserted-by":"crossref","first-page":"5440","DOI":"10.1021\/ol2020175","volume":"13","author":"Vall\u00e9e M. R. J.","year":"2011","journal-title":"Org. Lett."},{"key":"ref115\/cit115","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1021\/ar200059z","volume":"44","author":"Debets M. F.","year":"2011","journal-title":"Acc. Chem. Res."},{"key":"ref116\/cit116a","doi-asserted-by":"crossref","first-page":"7179","DOI":"10.1002\/anie.201402606","volume":"53","author":"Li X.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref116\/cit116b","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1021\/bc400122c","volume":"24","author":"Zeglis B. M.","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"ref116\/cit116c","doi-asserted-by":"crossref","first-page":"12994","DOI":"10.1021\/ja407739y","volume":"135","author":"Zhou Q.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref117\/cit117","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1021\/bc300364z","volume":"23","author":"Jang S.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref118\/cit118","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1021\/bc200365k","volume":"23","author":"van Geel R.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref119\/cit119","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.1021\/ja500364r","volume":"136","author":"Poole T. H.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref120\/cit120","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1002\/anie.201000408","volume":"49","author":"Ning X.","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref121\/cit121","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/anie.201106775","volume":"51","author":"Colombo M.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref122\/cit122","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1021\/ja1081519","volume":"133","author":"Sanders B. C.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref123\/cit123","doi-asserted-by":"crossref","first-page":"9376","DOI":"10.1039\/C4CC03816A","volume":"50","author":"Plougastel L.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref124\/cit124","doi-asserted-by":"crossref","first-page":"7303","DOI":"10.1039\/c1ob06424j","volume":"9","author":"St\u00f6ckmann H.","year":"2011","journal-title":"Org. Biomol. Chem."},{"key":"ref125\/cit125a","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1039\/c3ob27116a","volume":"11","author":"Li Y.","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"ref125\/cit125b","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1039\/c2sc20433a","volume":"3","author":"Li Y.","year":"2012","journal-title":"Chem. Sci."},{"key":"ref126\/cit126a","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1021\/bc300052u","volume":"23","author":"Thomas J. D.","year":"2012","journal-title":"Bioconjugate Chem."},{"key":"ref126\/cit126b","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/anie.200804514","volume":"48","author":"Kele P.","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref127\/cit127a","doi-asserted-by":"crossref","first-page":"4166","DOI":"10.1002\/anie.201108231","volume":"51","author":"Plass T.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref127\/cit127b","doi-asserted-by":"crossref","first-page":"3878","DOI":"10.1002\/anie.201008178","volume":"50","author":"Plass T.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref128\/cit128","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1039\/C4OB00505H","volume":"12","author":"Hommersom C. A.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref129\/cit129","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1039\/C3SC53332H","volume":"5","author":"Wallace S.","year":"2014","journal-title":"Chem. Sci."},{"key":"ref130\/cit130","doi-asserted-by":"crossref","first-page":"12568","DOI":"10.1039\/C4CC04117H","volume":"50","author":"Gattner M. J.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref131\/cit131a","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1002\/cbic.201300435","volume":"14","author":"Schneider S.","year":"2013","journal-title":"ChemBioChem"},{"key":"ref131\/cit131b","doi-asserted-by":"crossref","first-page":"7838","DOI":"10.1021\/ja101677r","volume":"132","author":"Han H.-S.","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"ref131\/cit131c","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1021\/bc500361d","volume":"25","author":"Kurra Y.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref132\/cit132a","doi-asserted-by":"crossref","first-page":"3176","DOI":"10.1039\/C3CC48682F","volume":"50","author":"Wang X. S.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref132\/cit132b","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1021\/cb400267m","volume":"8","author":"Lee Y.-J.","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"ref132\/cit132c","doi-asserted-by":"crossref","first-page":"9700","DOI":"10.1002\/anie.201303477","volume":"52","author":"Li F.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref132\/cit132d","doi-asserted-by":"crossref","first-page":"16766","DOI":"10.1021\/ja407867a","volume":"135","author":"Yu Z.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref132\/cit132e","doi-asserted-by":"crossref","first-page":"4466","DOI":"10.1002\/anie.201109252","volume":"51","author":"Kaya E.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref132\/cit132f","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/nchem.1250","volume":"4","author":"Lang K.","year":"2012","journal-title":"Nat. Chem."},{"key":"ref132\/cit132g","doi-asserted-by":"crossref","first-page":"10600","DOI":"10.1002\/anie.201205352","volume":"51","author":"Yu Z.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref133\/cit133","doi-asserted-by":"crossref","first-page":"13680","DOI":"10.1021\/ja407737d","volume":"135","author":"Kamber D. N.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref134\/cit134","doi-asserted-by":"crossref","first-page":"4153","DOI":"10.1021\/ja5012542","volume":"136","author":"Yu Z.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref135\/cit135","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1039\/C4SC01348D","volume":"5","author":"Darko A.","year":"2014","journal-title":"Chem. Sci."},{"key":"ref136\/cit136a","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/nchem.1919","volume":"6","author":"Wang K.","year":"2014","journal-title":"Nat. Chem."},{"key":"ref136\/cit136b","doi-asserted-by":"crossref","first-page":"7785","DOI":"10.1021\/ja4129789","volume":"136","author":"Sachdeva A.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref137\/cit137","doi-asserted-by":"crossref","first-page":"7798","DOI":"10.1002\/anie.200903135","volume":"48","author":"Floyd N.","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref138\/cit138","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1021\/ja401989p","volume":"135","author":"Li Q.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref139\/cit139","doi-asserted-by":"crossref","first-page":"10353","DOI":"10.1021\/jo501972m","volume":"79","author":"Jouanno L.-A.","year":"2014","journal-title":"J. Org. Chem."},{"key":"ref140\/cit140","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1021\/ol501049c","volume":"16","author":"Engelsma S. B.","year":"2014","journal-title":"Org. Lett."},{"key":"ref141\/cit141a","doi-asserted-by":"crossref","first-page":"6511","DOI":"10.1039\/C4CS00117F","volume":"43","author":"Yang M.","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"ref141\/cit141b","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.cbpa.2014.07.007","volume":"21","author":"Chankeshwara S. V.","year":"2014","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref142\/cit142a","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1039\/C2CC37832A","volume":"49","author":"Sasmal P. K.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref142\/cit142b","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.cbpa.2006.04.009","volume":"10","author":"Antos J. M.","year":"2006","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref143\/cit143","doi-asserted-by":"crossref","first-page":"13490","DOI":"10.1021\/ja054686c","volume":"127","author":"McFarland J. M.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref144\/cit144","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1021\/ja057106k","volume":"128","author":"Tilley S. D.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref145\/cit145","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1002\/cbic.200900003","volume":"10","author":"Chen S.","year":"2009","journal-title":"ChemBioChem"},{"key":"ref146\/cit146","doi-asserted-by":"crossref","first-page":"5776","DOI":"10.1016\/j.bmcl.2013.09.002","volume":"23","author":"Cser\u00e9p G. B.","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref147\/cit147a","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/anie.201307386","volume":"53","author":"Obermeyer A. C.","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref147\/cit147b","doi-asserted-by":"crossref","first-page":"7469","DOI":"10.1039\/C4CC01551G","volume":"50","author":"Ji A.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref147\/cit147c","doi-asserted-by":"crossref","first-page":"9572","DOI":"10.1021\/ja500728c","volume":"136","author":"Obermeyer A. C.","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref147\/cit147d","doi-asserted-by":"crossref","first-page":"16970","DOI":"10.1021\/ja206324q","volume":"133","author":"Seim K. L.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref148\/cit148","doi-asserted-by":"crossref","first-page":"10256","DOI":"10.1021\/ja047272c","volume":"126","author":"Antos J. M.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"ref149\/cit149","doi-asserted-by":"crossref","first-page":"6301","DOI":"10.1021\/ja900094h","volume":"131","author":"Antos J. M.","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"ref150\/cit150","doi-asserted-by":"crossref","first-page":"4166","DOI":"10.1039\/C2CC37323H","volume":"49","author":"Kundu R.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref151\/cit151","doi-asserted-by":"crossref","first-page":"4918","DOI":"10.1039\/c3cs35496b","volume":"42","author":"Gillingham D.","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"ref152\/cit152","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1039\/c2cc38214h","volume":"49","author":"On-Yee Chan A.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref153\/cit153","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev.biochem.052308.105824","volume":"79","author":"Liu C. C.","year":"2010","journal-title":"Annu. Rev. Biochem."},{"key":"ref154\/cit154a","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1002\/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4","volume":"41","author":"Rostovtsev V. V.","year":"2002","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref154\/cit154b","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/jo011148j","volume":"67","author":"Tornoe C. W.","year":"2002","journal-title":"J. Org. Chem."},{"key":"ref155\/cit155","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1038\/nature05757","volume":"446","author":"van Kasteren S. I.","year":"2007","journal-title":"Nature"},{"key":"ref156\/cit156","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1021\/bc500443h","volume":"25","author":"Raliski B. K.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref157\/cit157","doi-asserted-by":"crossref","first-page":"8142","DOI":"10.1039\/c0cc01576h","volume":"46","author":"Boutureira O.","year":"2010","journal-title":"Chem. Commun."},{"key":"ref158\/cit158","doi-asserted-by":"crossref","first-page":"9350","DOI":"10.1039\/C4OB01350F","volume":"12","author":"Diaz Velazquez H.","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"ref159\/cit159a","doi-asserted-by":"crossref","first-page":"8051","DOI":"10.1002\/anie.201101817","volume":"50","author":"Besanceney-Webler C.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref159\/cit159b","doi-asserted-by":"crossref","first-page":"17993","DOI":"10.1021\/ja2083027","volume":"133","author":"Kennedy D. C.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref159\/cit159c","doi-asserted-by":"crossref","first-page":"9879","DOI":"10.1002\/anie.200905087","volume":"48","author":"Hong V.","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref160\/cit160","doi-asserted-by":"crossref","first-page":"12056","DOI":"10.1002\/anie.201305645","volume":"52","author":"Kolodych S.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref161\/cit161","doi-asserted-by":"crossref","first-page":"12670","DOI":"10.1021\/ja075865s","volume":"129","author":"Tam A.","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"ref162\/cit162","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1002\/cbic.201200353","volume":"13","author":"Li J.","year":"2012","journal-title":"ChemBioChem"},{"key":"ref163\/cit163","doi-asserted-by":"crossref","first-page":"15316","DOI":"10.1021\/ja2066913","volume":"133","author":"Li N.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref164\/cit164","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1021\/cb500443x","volume":"9","author":"Lim R. K. V.","year":"2014","journal-title":"ACS Chem. Biol."},{"key":"ref165\/cit165","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1021\/bc500349h","volume":"25","author":"Hauke S.","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"ref166\/cit166","doi-asserted-by":"publisher","DOI":"10.1021\/cb500649q"},{"key":"ref167\/cit167","doi-asserted-by":"crossref","first-page":"7330","DOI":"10.1021\/ja402424j","volume":"135","author":"Li J.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref168\/cit168","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/nchem.1887","volume":"6","author":"Li J.","year":"2014","journal-title":"Nat. Chem."},{"key":"ref169\/cit169a","doi-asserted-by":"crossref","first-page":"6809","DOI":"10.1039\/c3cc43479f","volume":"49","author":"Cheng G.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref169\/cit169b","doi-asserted-by":"crossref","first-page":"11679","DOI":"10.1039\/C4CC02969K","volume":"50","author":"Cheng G.","year":"2014","journal-title":"Chem. Commun."},{"key":"ref170\/cit170","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1002\/cbic.200900002","volume":"10","author":"Lin Y. A.","year":"2009","journal-title":"ChemBioChem"},{"key":"ref171\/cit171a","doi-asserted-by":"crossref","first-page":"16805","DOI":"10.1021\/ja104994d","volume":"132","author":"Lin Y. A.","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"ref171\/cit171b","doi-asserted-by":"crossref","first-page":"9642","DOI":"10.1021\/ja8026168","volume":"130","author":"Lin Y. A.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref172\/cit172","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1039\/b908004j","author":"Chalker J. M.","year":"2009","journal-title":"Chem. Commun."},{"key":"ref173\/cit173","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.3762\/bjoc.6.140","volume":"6","author":"Lin Y. A.","year":"2010","journal-title":"Beilstein J. Org. Chem."},{"key":"ref174\/cit174","doi-asserted-by":"crossref","first-page":"12156","DOI":"10.1021\/ja403191g","volume":"135","author":"Lin Y. A.","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"ref175\/cit175","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1002\/anie.200905590","volume":"49","author":"Ai H.-W.","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref176\/cit176","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/cbic.201300714","volume":"15","author":"Ourailidou M. E.","year":"2014","journal-title":"ChemBioChem"},{"key":"ref177\/cit177","doi-asserted-by":"crossref","first-page":"9422","DOI":"10.1021\/jo902012m","volume":"74","author":"Crich D.","year":"2009","journal-title":"J. Org. Chem."},{"key":"ref178\/cit178","doi-asserted-by":"crossref","first-page":"9172","DOI":"10.1021\/jo061439y","volume":"71","author":"Crich D.","year":"2006","journal-title":"J. Org. Chem."},{"key":"ref179\/cit179","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/nchem.916","volume":"2","author":"Croft L.","year":"2010","journal-title":"Nat. Chem."},{"key":"ref180\/cit180","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1016\/j.tetlet.2005.03.094","volume":"46","author":"Ojida A.","year":"2005","journal-title":"Tetrahedron Lett."},{"key":"ref181\/cit181","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/cbic.200500290","volume":"7","author":"Kodama K.","year":"2006","journal-title":"ChemBioChem"},{"key":"ref182\/cit182","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/cbic.200600432","volume":"8","author":"Kodama K.","year":"2007","journal-title":"ChemBioChem"},{"key":"ref183\/cit183","doi-asserted-by":"crossref","first-page":"8220","DOI":"10.1002\/anie.200803240","volume":"47","author":"Brustad E.","year":"2008","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref184\/cit184","doi-asserted-by":"crossref","first-page":"16346","DOI":"10.1021\/ja907150m","volume":"131","author":"Chalker J. M.","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"ref185\/cit185","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1039\/c0cc04970k","volume":"47","author":"Spicer C. D.","year":"2011","journal-title":"Chem. Commun."},{"key":"ref186\/cit186","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1021\/ja209352s","volume":"134","author":"Spicer C. D.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref187\/cit187","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1039\/c3cc38824g","volume":"49","author":"Spicer C. D.","year":"2013","journal-title":"Chem. Commun."},{"key":"ref188\/cit188","doi-asserted-by":"crossref","first-page":"8652","DOI":"10.1021\/jo5014228","volume":"79","author":"Ma X.","year":"2014","journal-title":"J. Org. Chem."},{"key":"ref189\/cit189","doi-asserted-by":"crossref","first-page":"3916","DOI":"10.1002\/anie.201208626","volume":"52","author":"Dumas A.","year":"2013","journal-title":"Angew. Chem., Int. Ed."}],"container-title":["Chemical Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/cr500399p","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T03:36:09Z","timestamp":1681443369000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/cr500399p"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,20]]},"references-count":287,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,3,11]]}},"alternative-id":["10.1021\/cr500399p"],"URL":"https:\/\/doi.org\/10.1021\/cr500399p","relation":{},"ISSN":["0009-2665","1520-6890"],"issn-type":[{"value":"0009-2665","type":"print"},{"value":"1520-6890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,20]]}}}