{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T02:25:12Z","timestamp":1776738312148,"version":"3.51.2"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"15","license":[{"start":{"date-parts":[[2004,3,25]],"date-time":"2004-03-25T00:00:00Z","timestamp":1080172800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2004,3,25]],"date-time":"2004-03-25T00:00:00Z","timestamp":1080172800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2004,3,25]],"date-time":"2004-03-25T00:00:00Z","timestamp":1080172800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2004,4,1]]},"DOI":"10.1021\/ja031698u","type":"journal-article","created":{"date-parts":[[2004,4,14]],"date-time":"2004-04-14T05:02:29Z","timestamp":1081918949000},"page":"4750-4751","source":"Crossref","is-referenced-by-count":87,"title":["Glycodendriproteins:\u2009 A Synthetic Glycoprotein Mimic Enzyme with Branched Sugar-Display Potently Inhibits Bacterial Aggregation"],"prefix":"10.1021","volume":"126","author":[{"given":"Phillip M.","family":"Rendle","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"Andreas","family":"Seger","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"Joao","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"Neil J.","family":"Oldham","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"Richard R.","family":"Bott","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"J. Bryan","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"Marjorie M.","family":"Cowan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]},{"given":"Benjamin G.","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK, Genencor International,\r925 Page Mill Road, Palo Alto, California 94304, Department of Chemistry, University of Toronto,\rOntario M5S 5H6, Canada, and Department of Microbiology, Miami University, Oxford, Ohio 45056"}]}],"member":"316","published-online":{"date-parts":[[2004,3,25]]},"reference":[{"key":"ja031698ub00001\/ja031698ub00001_1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/978-1-4613-0415-9_6","volume":"408","author":"Beuth J.","year":"1996","journal-title":"Adv. Exp. Med. Biol."},{"key":"ja031698ub00002\/ja031698ub00002_1","first-page":"695","volume":"2","author":"Lingwood C. A.","year":"1999","journal-title":"Curr. Biol."},{"key":"ja031698ub00003\/ja031698ub00003_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9084(01)01291-3"},{"key":"ja031698ub00004\/ja031698ub00004_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar00056a001"},{"key":"ja031698ub00005\/ja031698ub00005_1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0021-9258(18)33240-X","volume":"258","author":"Lee Y. C.","year":"1983","journal-title":"J. Biol. Chem."},{"key":"ja031698ub00006\/ja031698ub00006_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr000418f"},{"key":"ja031698ub00007\/ja031698ub00007_1","first-page":"217","volume":"218","author":"Lindhorst T. K.","year":"2002","journal-title":"Top. Curr. Chem."},{"key":"ja031698ub00008\/ja031698ub00008_1","doi-asserted-by":"publisher","DOI":"10.1038\/35001095"},{"key":"ja031698ub00009\/ja031698ub00009_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja0258529"},{"key":"ja031698ub00010\/ja031698ub00010_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39930001869"},{"key":"ja031698ub00011\/ja031698ub00011_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr0004310"},{"key":"ja031698ub00012\/ja031698ub00012_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.57.070188.004033"},{"key":"ja031698ub00013\/ja031698ub00013_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00167a003"},{"key":"ja031698ub00014\/ja031698ub00014_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja961846z"},{"key":"ja031698ub00015\/ja031698ub00015_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo9816461"},{"key":"ja031698ub00016\/ja031698ub00016_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja992881j"},{"key":"ja031698ub00017\/ja031698ub00017_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-5521(00)90065-6"},{"key":"ja031698ub00018\/ja031698ub00018_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja029433n"},{"key":"ja031698ub00019\/ja031698ub00019_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2003.08.006"},{"key":"ja031698ub00020\/ja031698ub00020_1","doi-asserted-by":"publisher","DOI":"10.1039\/b009184g"},{"key":"ja031698ub00021\/ja031698ub00021_1","doi-asserted-by":"publisher","DOI":"10.1002\/1439-7633(20020902)3:9%3C836::AID-CBIC836%3E3.0.CO;2-2"},{"key":"ja031698ub00022\/ja031698ub00022_1","unstructured":"For further discussion, see SI."},{"key":"ja031698ub00023\/ja031698ub00023_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/30.1.343"},{"key":"ja031698ub00024\/ja031698ub00024_1","unstructured":"Multiple, indiscriminate ligands (e.g. ref (21)) fail."},{"key":"ja031698ub00025\/ja031698ub00025_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200300591"},{"key":"ja031698ub00026\/ja031698ub00026_1","doi-asserted-by":"crossref","first-page":"4403","DOI":"10.1128\/IAI.66.9.4403-4410.1998","volume":"66","author":"Hallberg K.","year":"1998","journal-title":"Infect. Immun."},{"key":"ja031698ub00027\/ja031698ub00027_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.11.6346-6354.2000"},{"key":"ja031698ub00028\/ja031698ub00028_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc970126u"},{"key":"ja031698ub00029\/ja031698ub00029_1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S0021-9258(19)35413-4","volume":"263","author":"Shibuya N.","year":"1988","journal-title":"J. Biol. Chem."},{"key":"ja031698ub00030\/ja031698ub00030_1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1128\/JCM.38.2.929-930.2000","volume":"38","author":"Wust J.","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"ja031698ub00031\/ja031698ub00031_1","doi-asserted-by":"publisher","DOI":"10.1080\/00313029800169695"},{"key":"ja031698ub00032\/ja031698ub00032_1","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-39-3-183"},{"key":"ja031698ub00033\/ja031698ub00033_1","unstructured":"A. naeslundii fimA may be functionally active as a dimer,(26) PNA as a tetramer. Bi-antennary complex glycoproteins are postulated to be natural fimA ligands.(27)"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja031698u","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja031698u","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T19:09:11Z","timestamp":1686251351000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ja031698u"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,25]]},"references-count":33,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2004,4,1]]}},"alternative-id":["10.1021\/ja031698u"],"URL":"https:\/\/doi.org\/10.1021\/ja031698u","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3,25]]}}}