{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:27:43Z","timestamp":1760783263938},"reference-count":19,"publisher":"American Chemical Society (ACS)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Eng. Data"],"published-print":{"date-parts":[[2010,9,9]]},"DOI":"10.1021\/je100021z","type":"journal-article","created":{"date-parts":[[2010,4,2]],"date-time":"2010-04-02T13:47:16Z","timestamp":1270216036000},"page":"3160-3163","source":"Crossref","is-referenced-by-count":6,"title":["Protonation Equilibria and Lipophilicity of Sarafloxacin"],"prefix":"10.1021","volume":"55","author":[{"given":"Ana I.","family":"Ca\u00e7o","sequence":"first","affiliation":[{"name":"CICECO, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portugal, Bayer Technology Services GmbH, Fluid Properties & Thermodynamics, Geb. B310, D-51368 Leverkusen, Germany, and Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, ITQB2, Universidade Nova de Lisboa, Av. Rep\u00fablica, Apartado 127, 2780-901 Oeiras, Portugal"}]},{"given":"Liliana C.","family":"Tom\u00e9","sequence":"additional","affiliation":[{"name":"CICECO, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portugal, Bayer Technology Services GmbH, Fluid Properties & Thermodynamics, Geb. B310, D-51368 Leverkusen, Germany, and Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, ITQB2, Universidade Nova de Lisboa, Av. Rep\u00fablica, Apartado 127, 2780-901 Oeiras, Portugal"}]},{"given":"Ralf","family":"Dohrn","sequence":"additional","affiliation":[{"name":"CICECO, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portugal, Bayer Technology Services GmbH, Fluid Properties & Thermodynamics, Geb. B310, D-51368 Leverkusen, Germany, and Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, ITQB2, Universidade Nova de Lisboa, Av. Rep\u00fablica, Apartado 127, 2780-901 Oeiras, Portugal"}]},{"given":"Isabel M.","family":"Marrucho","sequence":"additional","affiliation":[{"name":"CICECO, Departamento de Qu\u00edmica, Universidade de Aveiro, 3810-193 Aveiro, Portugal, Bayer Technology Services GmbH, Fluid Properties & Thermodynamics, Geb. B310, D-51368 Leverkusen, Germany, and Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica, ITQB2, Universidade Nova de Lisboa, Av. Rep\u00fablica, Apartado 127, 2780-901 Oeiras, Portugal"}]}],"member":"316","published-online":{"date-parts":[[2010,4,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1021\/ci700307p","volume":"48","author":"Hughes L. D.","year":"2008","journal-title":"J. Chem. Inf. Model."},{"key":"ref2\/cit2","volume-title":"Wiley series in Solution Chemistry","author":"Sangster J.","year":"1997"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/qsar.2660110408","volume":"11","author":"Avdeef A.","year":"1992","journal-title":"Quant. Struct.-Act. Relat."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0045-6535(03)00609-X","volume":"53","author":"Benfenati E.","year":"2003","journal-title":"Chemosphere"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/10629360701843649","volume":"19","author":"Geronikaki A.","year":"2008","journal-title":"SAR QSAR Environ. Res."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.jpba.2004.10.022","volume":"37","author":"Langlois M. H.","year":"2005","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"6368","DOI":"10.1021\/ie060055v","volume":"45","author":"Varanda F.","year":"2006","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0021-9673(04)01422-0","volume":"1051","author":"Lin C. E.","year":"2004","journal-title":"J. Chromatogr., Sect. A"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1016\/j.watres.2004.03.017","volume":"38","author":"Qiang Z.","year":"2004","journal-title":"Water Res."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0378-5173(94)00176-6","volume":"113","author":"Takacs-Novak K.","year":"1995","journal-title":"Int. J. Pharm."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/qsar.19890080405","volume":"8","author":"Hersey A.","year":"1989","journal-title":"Quant. Struct.-Act. Relat."},{"key":"ref11\/cit11a","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/qsar.19880070304","volume":"7","author":"Dearden J. C.","year":"1988","journal-title":"Quant. Struct.-Act. Relat."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0378-5173(92)90336-Z","volume":"88","author":"Ross D. L.","year":"1992","journal-title":"Int. J. Pharm."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0939-6411(03)00099-7","volume":"56","author":"Sun J.","year":"2003","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"51\u2212","DOI":"10.1016\/S0939-6411(02)00018-8","volume":"54","author":"Sun J.","year":"2002","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"4989","DOI":"10.1021\/es000917y","volume":"34","author":"Lutzhoft H. C. H.","year":"2000","journal-title":"Environ. Sci. Technol."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1021\/jm00015a021","volume":"38","author":"Renau T. E.","year":"1995","journal-title":"J. Med. Chem."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0003-2670(02)00435-X","volume":"464","author":"Jim\u00e9nez-Lozano E.","year":"2002","journal-title":"Anal. Chim. Acta"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/S0731-7085(96)02033-X","volume":"15","author":"Lizondo M.","year":"1997","journal-title":"J. Pharm. Biomed. Anal."}],"container-title":["Journal of Chemical & Engineering Data"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/je100021z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T03:33:25Z","timestamp":1680752005000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/je100021z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,2]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,9,9]]}},"alternative-id":["10.1021\/je100021z"],"URL":"https:\/\/doi.org\/10.1021\/je100021z","relation":{},"ISSN":["0021-9568","1520-5134"],"issn-type":[{"value":"0021-9568","type":"print"},{"value":"1520-5134","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,2]]}}}