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This mechanism is probably shared by other neurodegenerative disorders with polyglutamine expansion, including Huntington disease. Attempts at reproducing the Kennedy disease phenotype by introducing the expanded androgen receptor into cultured neuronal cells and transgenic animals have thus far been unsuccessful, but recently developed model systems with other expanded polyglutamine constructs should allow the pathogenesis of these diseases to be elucidated.<\/jats:p>","DOI":"10.1023\/a:1005344403603","type":"journal-article","created":{"date-parts":[[2002,12,21]],"date-time":"2002-12-21T21:48:34Z","timestamp":1040507314000},"page":"152-158","source":"Crossref","is-referenced-by-count":103,"title":["Kennedy disease"],"prefix":"10.1002","volume":"20","author":[{"given":"K. 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