{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T11:07:15Z","timestamp":1776942435512,"version":"3.51.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2000,2]]},"DOI":"10.1023\/a:1005437331967","type":"journal-article","created":{"date-parts":[[2002,12,21]],"date-time":"2002-12-21T17:25:23Z","timestamp":1040491523000},"page":"394-397","source":"Crossref","is-referenced-by-count":59,"title":["Iron Supplementation May Aggravate Inflammatory Status of Colitis in a Rat Model"],"prefix":"10.1007","volume":"45","author":[{"given":"Ram","family":"Reifen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zippora","family":"Matas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilian","family":"Zeidel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zippi","family":"Berkovitch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoram","family":"Bujanover","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"222115_CR1","doi-asserted-by":"crossref","unstructured":"Grisham MB, Yamada T: Neutrophils nitrogen oxides and inflammatory bowel disease. Ann NY Acad Sci 30-115, 1992","DOI":"10.1111\/j.1749-6632.1992.tb39753.x"},{"key":"222115_CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0748-5514(85)90025-X","volume":"1","author":"SD Aust","year":"1986","unstructured":"Aust SD, Morehouse LA, Thomas CE: Role of metals in oxygen radical reactions. Free Radic Biol Med 1:3-25, 1986","journal-title":"Free Radic Biol Med"},{"key":"222115_CR3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1021\/tx00032a001","volume":"2","author":"G Minotti","year":"1993","unstructured":"Minotti G: Sources and role of iron in lipid peroxidation. Chem Res Toxicol 2:134-146, 1993","journal-title":"Chem Res Toxicol"},{"key":"222115_CR4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0891-5849(93)90001-B","volume":"14","author":"J Vav der Zee","year":"1993","unstructured":"Vav der Zee J, Krootjes BBH, Chignel CF, Dubbelman TMAR, VanSteveninck J: Hydroxyl radical generation by a light dependent Fenton reaction. Free Radic Biol Med 14:105-113, 1993","journal-title":"Free Radic Biol Med"},{"key":"222115_CR5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0076-6879(90)86093-B","volume":"186","author":"B Halliwel","year":"1990","unstructured":"Halliwel B, Cutteridge JC: Role of free radicals and catalytic metral ions in human disease: An overview. Methods Enzymol 186:1-8, 1990","journal-title":"Methods Enzymol"},{"key":"222115_CR6","unstructured":"Health and Human Services Committee: Guide for the Care and Use of Laboratory Animals. Publication 85-21. Bethesda, Maryland, National Institutes of Health"},{"key":"222115_CR7","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/1523-1747.ep12506462","volume":"78","author":"PP Bradly","year":"1982","unstructured":"Bradly PP, Priebat DA, Christensen RD, Rothestein G: Measurement of cutaneous inflammation estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78:206-209, 1982","journal-title":"J Invest Dermatol"},{"key":"222115_CR8","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","volume":"52","author":"JA Buege","year":"1978","unstructured":"Buege JA, Aust SD: Microsomal lipid peroxidation. Methods Enzymol 52:302-306, 1978","journal-title":"Methods Enzymol"},{"key":"222115_CR9","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0140-6736(94)92831-2","volume":"334","author":"MB Grisham","year":"1994","unstructured":"Grisham MB: Oxidants and free radicals in inflammatory bowel disease. The Lancet 334:859-861, 1994","journal-title":"The Lancet"},{"key":"222115_CR10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF02534503","volume":"19","author":"CJ Dillard","year":"1979","unstructured":"Dillard CJ, Downey JE, Tappel AL: Effect of antioxidants on lipid peroxidation in iron-loaded rats. Lipids 19:127-133, 1979","journal-title":"Lipids"},{"key":"222115_CR11","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1093\/jn\/113.11.2266","volume":"113","author":"CJ Dillard","year":"1983","unstructured":"Dillard CJ, Gavino VC, Tappel AL: Relative antioxidant effectiveness of a tocoperol in iron loaded rats. J Nutr 113:2266-2273, 1983","journal-title":"J Nutr"},{"key":"222115_CR12","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1093\/jn\/120.3.280","volume":"120","author":"WH Wu","year":"1990","unstructured":"Wu WH, Meydani M, Meydani SN, Burklund PM, Blumberg JB, Munro HN: Effect of dietary iron overload on lipid peroxidation prostaglandin synthesis and lymphocyte proliferation in young and old rats. J Nutr 120:280-289, 1990","journal-title":"J Nutr"},{"key":"222115_CR13","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0891-5849(92)90079-V","volume":"13","author":"CF Babbs","year":"1992","unstructured":"Babbs CF: Oxygen radicals in ulcerative colitis. Free Radic Biol Med 13:169-181, 1992","journal-title":"Free Radic Biol Med"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005437331967.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1005437331967\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005437331967.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T03:08:40Z","timestamp":1752462520000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1005437331967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["222115"],"URL":"https:\/\/doi.org\/10.1023\/a:1005437331967","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,2]]}}}