{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:12:51Z","timestamp":1771002771579,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1999,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe the results of bone marrow transplantation (BMT) in four patients with mucopolysaccharidosis type VI (MPS VI, McKusick 253200) \u2013 Maroteaux\u2013Lamy disease. The indications for transplantation were cardiomyopathy in three patients and severe obstructive sleep apnoea in one. The follow\u2010up period ranges between 1 and 9 years, and three of the patients are at mainstream schools. In all of the patients the facial features have become less coarse and the cardiac manifestations have improved or remained stable. However, skeletal changes have persisted or even progressed, although posture and joint mobility have improved and all the patients have remained ambulatory and active. BMT appears to prolong survival and improve the quality of life in MPS VI patients, but careful selection of patients is essential.<\/jats:p>","DOI":"10.1023\/a:1005447232027","type":"journal-article","created":{"date-parts":[[2002,12,21]],"date-time":"2002-12-21T22:25:23Z","timestamp":1040509523000},"page":"50-62","source":"Crossref","is-referenced-by-count":112,"title":["Bone marrow transplantation for Maroteaux\u2013Lamy syndrome (MPS VI): Long\u2010term follow\u2010up"],"prefix":"10.1002","volume":"22","author":[{"given":"E.","family":"Herskhovitz","sequence":"first","affiliation":[{"name":"Metabolic Unit Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Chemical Pathology Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Rainer","sequence":"additional","affiliation":[{"name":"Department of Chemical Pathology Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. M.","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Radiology Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Lidchi","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Radiology Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Vellodi","sequence":"additional","affiliation":[{"name":"Metabolic Unit Great Ormond Street Hospital for Children NHS Trust  Great Ormond Street London WC1N 3JH UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,2]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"2702","article-title":"Reciprocal corneal transplantation fails to correct mucopolysaccharidosis VI corneal storage","volume":"33","author":"Aguirre G","year":"1992","journal-title":"Invest Ophthalmol V is Sci"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119208"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(75)90183-9"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.73.3.259"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050213"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92597-X"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1994.tb03125.x"},{"key":"e_1_2_1_9_1","first-page":"47","article-title":"Maroteaux\u2010Lamy syndrome (mucopolysaccharidosis type VI). 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