{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:48:50Z","timestamp":1791038930807,"version":"4.1.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2000,5,1]],"date-time":"2000-05-01T00:00:00Z","timestamp":957139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,5,1]],"date-time":"2000-05-01T00:00:00Z","timestamp":957139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2000,5]]},"DOI":"10.1023\/a:1005500403066","type":"journal-article","created":{"date-parts":[[2002,12,21]],"date-time":"2002-12-21T17:31:09Z","timestamp":1040491869000},"page":"854-863","source":"Crossref","is-referenced-by-count":43,"title":["Significance of Autonomic Nervous System Activity in Functional Dyspepsia"],"prefix":"10.1007","volume":"45","author":[{"given":"Eric R.","family":"Muth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth L.","family":"Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M.","family":"Stern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"223530_CR1","doi-asserted-by":"crossref","first-page":"A99","DOI":"10.1016\/0016-5085(91)90588-C","volume":"100","author":"KL Koch","year":"1991","unstructured":"Koch KL, Bingaman S, Sperry N, Stern RM: Electrogastrography differentiates mechanical vs idiopathic gastroparesis in patients with nausea and vomiting. Gastroenterology 100:A99, 1991","journal-title":"Gastroenterology"},{"key":"223530_CR2","first-page":"145","volume":"4","author":"NJ Talley","year":"1991","unstructured":"Talley NJ, Colin-Jones D, Koch KL, Koch M, Nyren O, Stanghellini V: Functional dyspepsia: A classification with guidelines for diagnosis and management. Gastroenterol Int 4:145-160, 1991","journal-title":"Gastroenterol Int"},{"key":"223530_CR3","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/0016-5085(93)90142-Y","volume":"105","author":"NJ Talley","year":"1993","unstructured":"Talley NJ, Weaver AL, Tesmer DL, Zinsmeister AR: Lack of discriminant value of dyspepsia subgroups in patients referred for upper endoscopy. Gastroenterology 105:1378-1386, 1993","journal-title":"Gastroenterology"},{"key":"223530_CR4","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/0016-5085(94)90775-7","volume":"106","author":"M Camilleri","year":"1994","unstructured":"Camilleri M, Ford MJ: Functional gastrointestinal disease and the autonomic nervous system: a way ahead? Gastroenterology 106:1114-1118, 1994","journal-title":"Gastroenterology"},{"key":"223530_CR5","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/0016-5085(91)70018-S","volume":"100","author":"MP Greydanus","year":"1991","unstructured":"Greydanus MP, Vassallo M, Camilleri M, Nelson DK, Hanson RB, Thomforde GM: Neurohormonal factors in functional dyspepsia: insights on pathophysiological mechanisms. Gastroenterology 100:1311-1318, 1991","journal-title":"Gastroenterology"},{"key":"223530_CR6","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00006842-199301000-00004","volume":"55","author":"T Hausken","year":"1993","unstructured":"Hausken T, Svebak S, Wilhelmsen I, Haug TT, Olafsen K, Pettersson E, Hveem K, Berstad A: Low vagal tone and antral dysmotility in patients with functional dyspepsia. Psychosom Med 55:12-22, 1993","journal-title":"Psychosom Med"},{"key":"223530_CR7","first-page":"81","volume":"56","author":"TT Haug","year":"1994","unstructured":"Haug TT, Svebak S, Hausken T, Wilhelmsen I, Berstad A, Ursin H: Low vagal activity as mediating mechanism for the relationship between personality factors and gastric symptoms in functional dyspepsia. Psychosom Med 56:81-186, 1994","journal-title":"Psychosom Med"},{"key":"223530_CR8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1136\/gut.30.1.54","volume":"30","author":"P Kerlin","year":"1989","unstructured":"Kerlin P: Post-prandial antral hypomotility in patients with idiopathic nausea and vomiting. Gut 30:54-59, 1989","journal-title":"Gut"},{"key":"223530_CR9","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1469-8986.1992.tb01685.x","volume":"29","author":"SHJ Uijtdehaage","year":"1992","unstructured":"Uijtdehaage SHJ, Stern RM, Koch KL: Effects of eating on vection-induced motion sickness, cardiac vagal tone, and gastric myoelectric activity. Psychophysiology 29:193-201, 1992.","journal-title":"Psychophysiology"},{"key":"223530_CR10","first-page":"308","volume":"62","author":"S Hu","year":"1991","unstructured":"Hu S, Grant W, Stern RM, Koch KL: Motion sickness severity and physiological correlates of repeated exposure to a rotating optokinetic drum. Aviat Space Environ Med 62:308-314, 1991","journal-title":"Aviat Space Environ Med"},{"key":"223530_CR11","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1136\/adc.67.5.613","volume":"65","author":"S Cucchirara","year":"1992","unstructured":"Cucchirara S, Riezzo G, Minella R, Pezzolla F, Giorgio I, auricchia S: Electrogastrography in non-ulcer dyspepsia. Arch Dis Child 65:613-617, 1992","journal-title":"Arch Dis Child"},{"key":"223530_CR12","first-page":"A469","volume":"102","author":"KL Koch","year":"1992","unstructured":"Koch KL, Medina M, Bingaman S, Stern RM: Gastric dysrhythmias and visceral sensations in patients with functional dyspepsia. Gastroenterology 102:A469, 1992","journal-title":"Gastroenterology"},{"key":"223530_CR13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/0016-5085(87)90843-2","volume":"92","author":"RM Stern","year":"1987","unstructured":"Stern RM, Koch KL, Stewart WR, Lindblad IM: Spectral analysis of tachygastria recorded during motion sickness. Gastroenterology 92:92-97, 1987","journal-title":"Gastroenterology"},{"key":"223530_CR14","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1365-2362.1995.tb01725.x","volume":"25","author":"HJ Jebbink","year":"1995","unstructured":"Jebbink HJ, Van Berge-Henegouwen GP, Bruijs PP, Akkermans LM, Smout AJ: Gastric myoelectrical activity and gastrointestinal motility in patients with functional dyspepsia. Eur J Clin Invest 25:429-437, 1995","journal-title":"Eur J Clin Invest"},{"key":"223530_CR15","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/BF01540334","volume":"34","author":"R Jian","year":"1989","unstructured":"Jian R, Ducrot F, Ruskone A: Symptomatic radionuclide and therapeutic assessment of chronic idiopathic dyspepsia. A double-blind placebo-controlled evaluation of cisapride. Dig Dis Sci 34:657-664, 1989","journal-title":"Dig Dis Sci"},{"key":"223530_CR16","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/BF02888234","volume":"15","author":"YG Liu","year":"1995","unstructured":"Liu YG, Nie YQ, Yi CQ, Zhang JK: Study of gastric and gallbladder kinetics with real-time ultrasonography in cases of functional dyspepsia. J Tongji Med Univ 15:190-192, 1995","journal-title":"J Tongji Med Univ"},{"key":"223530_CR17","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1053\/gast.1996.v110.pm8612991","volume":"110","author":"V Stanghellini","year":"1996","unstructured":"Stanghellini V, Tosetti C, Paternico A, Barbara G, Morselli-Labate AM, Monetti N, Marengo M, Corinaldesi R: Risk indicators of delayed gastric emptying of solids in patients with functional dyspepsia. Gastroenterology 110:1036-1042, 1996","journal-title":"Gastroenterology"},{"key":"223530_CR18","first-page":"1579","volume":"36","author":"JL Urbain","year":"1995","unstructured":"Urbain JL, Vekemans MC, Parkman H, Van Cauteren J, Mayeur SM, Van den Maegdenbergh V, Charkes ND, Fisher RS, Malmud LS, De Roo M: Dynamic antral scintigraphy to characterize gastric antral motility in functional dyspepsia. J Nucl Med 36:1579-1586, 1995","journal-title":"J Nucl Med"},{"key":"223530_CR19","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1365-2982.1996.tb00271.x","volume":"8","author":"NK Ahluwalia","year":"1996","unstructured":"Ahluwalia NK, Thompson DG, Mamtora H, Hindle J: Evaluation of gastric antral motor performance in patients with dysmotility-like dyspepsia using real-time high resolution ultrasound. Neurogastroenterol Motil 8:333-338, 1996","journal-title":"Neurogastroenterol Motil"},{"key":"223530_CR20","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1365-2982.1996.tb00266.x","volume":"8","author":"EMM Quigley","year":"1996","unstructured":"Quigley EMM: Symptoms and gastric function in dyspepsia-good-bye to gastroparesis? Neurogastroenterol Motil 8:273-275, 1996","journal-title":"Neurogastroenterol Motil"},{"key":"223530_CR21","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0016-5085(90)91012-U","volume":"99","author":"NJ Talley","year":"1990","unstructured":"Talley NJ, Phillips SF, Bruce B, Twomey CK, Zinsmeister AR, Melton LJ: Relation among personality and symptoms in nonulcer dyspepsia and the irritable bowel syndrome. Gastroenterology 99:327-333, 1990","journal-title":"Gastroenterology"},{"key":"223530_CR22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3109\/00365529509093244","volume":"30","author":"TT Haug","year":"1995","unstructured":"Haug TT, Wilhelmsen I, Ursin H, Berstad A: What are the real problems for patients with functional dyspepsia. Scand J Gastroenterol 30:97-100, 1995","journal-title":"Scand J Gastroenterol"},{"key":"223530_CR23","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/0016-5085(86)90864-4","volume":"90","author":"NJ Talley","year":"1986","unstructured":"Talley NJ, Fung LH, Gilligan IJ, McNeil D, Piper DW: Association of anxiety, neuroticism, and depression with dyspepsia of unknown cause. A case-control study. Gastroenterology 90:886-892, 1986","journal-title":"Gastroenterology"},{"key":"223530_CR24","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1176\/ajp.144.9.1222","volume":"144","author":"G Magni","year":"1987","unstructured":"Magni G, di Mario F, Bernasconi G, Mastropaola G: DSM-III diagnoses associated with dyspepsia of unknown cause. Am J Psychiatry 144:1222-1223, 1987","journal-title":"Am J Psychiatry"},{"key":"223530_CR25","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0022-3999(94)00086-K","volume":"39","author":"BH Jonsson","year":"1995","unstructured":"Jonsson BH, Theorell T, Gotthard R: Symptoms and personality in patients with chronic functional dyspepsia. J Psychosom Res 39:93-102, 1995","journal-title":"J Psychosom Res"},{"key":"223530_CR26","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/BF02064207","volume":"40","author":"I Wilhelmsen","year":"1995","unstructured":"Wilhelmsen I, Haug TT, Ursin H, Berstad A: Discriminant analysis of factors distinguishing patients with functional dyspepsia from patients with duodenal ulcer. Significance of somatization. Dig Dis Sci 40:1105-1111, 1995","journal-title":"Dig Dis Sci"},{"key":"223530_CR27","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1152\/jappl.1967.23.6.964","volume":"23","author":"Y Kawakami","year":"1967","unstructured":"Kawakami Y, Natelson BH, DuBois AB: Cardiovascular effects of face immersion and factors affecting diving reflex in man. J Appl Physiol 23:964-970, 1967","journal-title":"J Appl Physiol"},{"key":"223530_CR28","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/0006-3223(93)90087-T","volume":"34","author":"BH Friedman","year":"1993","unstructured":"Friedman BH, Thayer JF, Borkovec TD, Tyrrell RA, Johnsen B-H, Columbo R: Autonomic characteristics of non-clinical panic and blood phobia. Biol Psychiatry 34:298-310, 1993","journal-title":"Biol Psychiatry"},{"key":"223530_CR29","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF02691389","volume":"30","author":"RA Tyrrell","year":"1995","unstructured":"Tyrrell RA, Thayer JF, Friedman BH, Leibowitz HW, Francis EL: A behavioral link between the oculomotor and cardiovascular systems. Integ Physiol Behav Sci 30:46-67, 1995","journal-title":"Integ Physiol Behav Sci"},{"key":"223530_CR30","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1469-8986.1988.tb01909.x","volume":"25","author":"MH Pollak","year":"1988","unstructured":"Pollak MH, Obrist P: Effects of autonomic blockade on heart rate responses to reaction time and sustained handgrip tasks. Psychophysiology 25:689-695, 1988","journal-title":"Psychophysiology"},{"key":"223530_CR31","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1469-8986.1991.tb00412.x","volume":"28","author":"P Grossman","year":"1991","unstructured":"Grossman P, Karemaker J, Wieling W: Prediction of tonic parasympathetic cardiac control using respiratory sinus arrhythmia: The need for respiratory control. Psychophysiology 28:201-216, 1991","journal-title":"Psychophysiology"},{"key":"223530_CR32","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/j.1469-8986.1990.tb03198.x","volume":"27","author":"P Grossman","year":"1990","unstructured":"Grossman P, van Beek J, Wientjes C: A comparison of three quantification methods for estimation of respiratory sinus arrhythmia. Psychophysiology 27:702-714, 1990","journal-title":"Psychophysiology"},{"key":"223530_CR33","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0022-3999(95)00638-9","volume":"40","author":"ER Muth","year":"1996","unstructured":"Muth ER, Thayer JF, Stern RM, Koch KL: Assessment of the multiple dimensions of nausea: The nausea profile (NP). J Psychosom Med 40:511-520, 1996","journal-title":"J Psychosom Med"},{"key":"223530_CR34","volume-title":"The NEO-PR-R\/NEO-FFI professional manual","author":"PT Costa","year":"1992","unstructured":"Costa, PT, McCrae RR: The NEO-PR-R\/NEO-FFI professional manual. Odessa, Florida, Psychological Assessment Resources, 1992"},{"key":"223530_CR35","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1467-6494.1992.tb00978.x","volume":"60","author":"TW Smith","year":"1992","unstructured":"Smith TW, Williams PG: Personality and health: advantages and limitation of the five-factor model. J Pers 60:395-423, 1992","journal-title":"J Pers"},{"key":"223530_CR36","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0033-3182(91)72086-0","volume":"32","author":"GJ Taylor","year":"1991","unstructured":"Taylor GJ, Bagby RM, Parker JDA: The alexithymia construct. Psychosomatics 32:153-164, 1991","journal-title":"Psychosomatics"},{"key":"223530_CR37","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0022-3999(94)90005-1","volume":"38","author":"RM Bagby","year":"1994","unstructured":"Bagby RM, Parker JDA, Taylor GJ: The twenty-item Toronto alexithymia scale-I: Item selection and cross-validation of the factor structure. J Psychosom Res 38:23-32, 1994","journal-title":"J Psychosom Res"},{"key":"223530_CR38","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0022-3999(94)90006-X","volume":"38","author":"RM Bagby","year":"1994","unstructured":"Bagby RM, Parker JDA, Taylor GJ: The twenty-item Toronto alexithymia scale-II: Convergent, discriminant and concurrent validity. J Psychosom Res 38:33-40, 1994","journal-title":"J Psychosom Res"},{"key":"223530_CR39","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0005-7967(90)90135-6","volume":"28","author":"TJ Meyer","year":"1990","unstructured":"Meyer TJ, Miller ML, Metzger RL, Borkovec TD: Development and validation of the Penn State worry questionnaire. Behav Res Ther 28:487-495, 1990","journal-title":"Behav Res Ther"},{"key":"223530_CR40","first-page":"29","volume":"4","author":"E Mezzacappa","year":"1994","unstructured":"Mezzacappa E, Kindlon D, Earls F: The utility of spectral analytic techniques in the study of the autonomic regulation of beat-to-beat heart rate variability. Int J Methods Psychiatr Res 4:29-44, 1994","journal-title":"Int J Methods Psychiatr Res"},{"key":"223530_CR41","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0301-0511(92)90013-K","volume":"34","author":"P Grossman","year":"1992","unstructured":"Grossman P: Respiratory and cardiac rhythms as windows to central and autonomic biobehavioral regulation: Selection of window frames, keeping the panes clean and viewing the neural topography. Biol Psychol 34:131-161, 1992","journal-title":"Biol Psychol"},{"key":"223530_CR42","first-page":"23","volume-title":"The Ubiquity of Chaos","author":"AL Golberger","year":"1990","unstructured":"Golberger AL, Rigney DR: Sudden death is not chaos. In The Ubiquity of Chaos. S Krasner (ed). Washington, DC, American Association for the Advancement of Science, 1990, pp 23-34"},{"key":"223530_CR43","first-page":"554","volume-title":"Principles of Psychophysiology: Physical, Social and Inferential Elements","author":"RM Stern","year":"1990","unstructured":"Stern RM, Koch KL, Vasey MW: The gastrointestinal system. In Principles of Psychophysiology: Physical, Social and Inferential Elements. JT Cacioppo, LG Tassinary (eds). New York, Cambridge University Press, 1990, pp 554-579"},{"key":"223530_CR44","first-page":"290","volume-title":"An Illustrated Guide to Gastrointestinal Motility","author":"KL Koch","year":"1993","unstructured":"Koch KL, Stern RM: Electrogastrography. In An Illustrated Guide to Gastrointestinal Motility, (2nd ed.) D Kumar, D Wingate (eds). London, Churchill Livingstone, 1993, pp 290-307","edition":"2nd ed."},{"key":"223530_CR45","first-page":"1069","volume":"84","author":"KL Koch","year":"1989","unstructured":"Koch KL, Stern RM, Stewart WR, Vasey MW: Gastric emptying and gastric myoelectrical activity in patients with diabetic gastroparesis: Effect of long-term domperidone treatment. Am J Gastroenterol 84:1069-1075, 1989","journal-title":"Am J Gastroenterol"},{"key":"223530_CR46","first-page":"158","volume-title":"Atlas of Gastrointestinal Motility: In Health and Disease","author":"KL Koch","year":"1993","unstructured":"Koch KL: Stomach. In Atlas of Gastrointestinal Motility: In Health and Disease. MM Schuster (ed). Baltimore, Williams and Wilkins. 1993, pp 158-176"},{"key":"223530_CR47","first-page":"510","volume-title":"Autonomic Failure: A Textbook of Clinical Disorders of the Autonomic Nervous System","author":"DL Wingate","year":"1992","unstructured":"Wingate DL: Autonomic dysfunction and the gut. In Autonomic Failure: A Textbook of Clinical Disorders of the Autonomic Nervous System, 3rd ed. SR Bannister, CJ Mathias (eds). Oxford, Oxford University Press. 1992, pp 510-528","edition":"3rd ed."},{"key":"223530_CR48","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1007\/BF01299904","volume":"38","author":"AM Scott","year":"1993","unstructured":"Scott AM, Kellow JE, Shuter B, Cowan H, Corbett AM, Riley JW, Lunzer MR, Eckstein RP, Hoschl R, Lam SK, Jones MP: Intragastric distribution and gastric emptying of solids and liquids in functional dyspepsia: Lack of influence of symptoms and subgroups and H. pylori associated gastritis. Dig Dis Sci 38:2247-2254, 1993","journal-title":"Dig Dis Sci"},{"key":"223530_CR49","first-page":"199","volume-title":"Electrogastrography: Principles and Applications","author":"RM Stern","year":"1994","unstructured":"Stern RM, Koch KL: Using the electrogastrogram to study motion sickness. In Electrogastrography: Principles and Applications. JZ Chen, RW McCallum (eds). New York, Raven Press. 1994, pp 199-218"},{"key":"223530_CR50","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1007\/BF01296514","volume":"31","author":"M Camilleri","year":"1986","unstructured":"Camilleri M, Malagelada JR, Kao PC, Zinsmeister AR: Gastric and autonomic responses to stress in functional dyspepsia. Dig Dis Sci 31:1169-1177, 1986","journal-title":"Dig Dis Sci"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005500403066.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1005500403066\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005500403066.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T03:03:43Z","timestamp":1752462223000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1005500403066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,5]]}},"alternative-id":["223530"],"URL":"https:\/\/doi.org\/10.1023\/a:1005500403066","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}