{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:18:58Z","timestamp":1759033138937,"version":"3.41.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Autism Dev Disord"],"published-print":{"date-parts":[[2001,2]]},"DOI":"10.1023\/a:1005669915105","type":"journal-article","created":{"date-parts":[[2002,12,21]],"date-time":"2002-12-21T23:07:17Z","timestamp":1040512037000},"page":"89-96","source":"Crossref","is-referenced-by-count":32,"title":["A Family Genetic Study of Autism Associated with Profound Mental Retardation"],"prefix":"10.1007","volume":"31","author":[{"given":"Elizabeth","family":"Starr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sibel Kazak","family":"Berument","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Pickles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Tomlins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina","family":"Papanikolaou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Rutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"294530_CR1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1192\/bjp.138.5.416","volume":"138","author":"G. August","year":"1981","unstructured":"August, G., Stewart, M., & Tsai, L. (1981). The incidence of cognitive disabilities in the siblings of autistic children. British Journal of Psychiatry, 138416-422.","journal-title":"British Journal of Psychiatry"},{"key":"294530_CR2","first-page":"389","volume":"75","author":"A. Bailey","year":"1992","unstructured":"Bailey, A., & Rutter, M. (1992). Autism. Science Progress Edinburgh, 75389-402.","journal-title":"Science Progress Edinburgh"},{"key":"294530_CR3","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1469-7610.1993.tb01064.x","volume":"34","author":"A. Bailey","year":"1993","unstructured":"Bailey, A., Bulter, L., Le Couteur, A., Murphy, M., Scott, S., Webb, T., & Rutter, M. (1993). Prevalence of the Fragile X anomaly amongst autistic twins and singletons. Journal of Child Psychology and Psychiatry, 34673-688.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"294530_CR4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1023\/A:1026048320785","volume":"28","author":"A. Bailey","year":"1998","unstructured":"Bailey, A., Palfreman, S., Heavey, L., & Le Couteur, A. (1998). Autism: The phenotype in relatives. Journal of Autism and Developmental Disorders, 28369-392.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1469-7610.1996.tb01381.x","volume":"37","author":"A. Bailey","year":"1996","unstructured":"Bailey, A., Phillips, W., & Rutter, M. (1996). Autism: towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. Journal of Child Psychology and Psychiatry, 3789-126.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"294530_CR6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF01531501","volume":"15","author":"T. Baird","year":"1985","unstructured":"Baird, T., & August, G. (1985). Familial heterogeneity in infantile autism. Journal of Autism and Developmental Disorders, 15315-321.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR7","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1111\/j.1469-7610.1994.tb02300.x","volume":"35","author":"P. Bolton","year":"1994","unstructured":"Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S, Crowson, M., Bailey, A., & Rutter, M. (1994). A case-control family history study of autism. Journal of Child Psychology and Psychiatry, 35877-900.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"294530_CR8","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/00004583-199702000-00018","volume":"36","author":"P. Bolton","year":"1997","unstructured":"Bolton, P., Murphy, M., Macdonald, H., Whitlock, B., Pickles, A., & Rutter, M. (1997). Obstetric complications in autism: Consequences or causes of the condition? Journal of the American Academy of Child and Adolescent Psychiatry, 36272-281.","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"294530_CR9","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1023\/A:1025891824269","volume":"27","author":"P. Boutin","year":"1997","unstructured":"Boutin, P., Maziade, M. M\u00e9rette, C., Mondor, M., B\u00e9dard, C., & Thivierge, J. (1997). Family history of cognitive disabilities in first-degree relatives of autistic and mentally retarded children. Journal of Autism and Developmental Disorders, 27165-176.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR10","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/BF02179373","volume":"25","author":"P. DiLavore","year":"1995","unstructured":"DiLavore, P., Lord, C., & Rutter, M. (1995). The Pre-Linguistic Autism Diagnostic Observation Schedule. Journal of Autism and Developmental Disorders, 25355-379.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/978-1-4899-1992-2_5","volume-title":"Neurobiological issues in autism","author":"S. Folstein","year":"1987","unstructured":"Folstein, S., & Rutter, M., (1987). Autism: Familial aggregation and genetic implications. In E. Schopler & G. Mesibov (Eds.), Neurobiological issues in autism(pp. 83-105). New York: Plenum Press."},{"key":"294530_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-7610.1997.tb01694.x","volume":"38","author":"E. Fombonne","year":"1997","unstructured":"Fombonne, E., Bolton, P., Prior, J., Jordan, H., & Rutter, M. (1997). A family study of autism: Cognitive patterns and levels in parents and siblings. Journal of Child Psychology and Psychiatry, 381-17.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"294530_CR13","volume-title":"The biology of the autistic syndromes","author":"C. Gillberg","year":"1992","unstructured":"Gillberg, C., & Coleman, M. (1992). The biology of the autistic syndromes (2nd edition).London: MacKeith Press.","edition":"2nd edition"},{"key":"294530_CR14","first-page":"221","volume-title":"Proceedings of the Fifth Berkeley Symposium in Mathematical Statistics and Probability","author":"P. J. Huber","year":"1967","unstructured":"Huber, P. J. (1967). The behavior of maximum likelihood estimates under non-standard conditions. In Proceedings of the Fifth Berkeley Symposium in Mathematical Statistics and Probability(pp. 221-233). Berkeley: University of California Press."},{"key":"294530_CR15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/BF02211816","volume":"18","author":"M. Jones","year":"1988","unstructured":"Jones, M., & Szatmari, P. (1988). Stoppage rules and genetic studies of autism. Journal of Autism and Developmental Disorders, 1831-40.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR16","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1111\/j.1469-7610.1996.tb01475.x","volume":"37","author":"A. Le Couteur","year":"1996","unstructured":"Le Couteur, A., Bailey, A. J., Goode, S., Pickles, A., Robertson, S., Gottesman, I., & Rutter, M. (1996). A broader phenotype of autism: The clinical spectrum in twins. Journal of Child Psychology and Psychiatry, 37785-801. Leiter, R. (1948). The Leiter International Performance Scale.Chicago: Stoelting. Liang, K-Y., and Zeger, S. L. (1986). Longitudinal data analysis using generalized linear models. Biometrika, 7313-22.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"294530_CR17","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF02211841","volume":"19","author":"C. Lord","year":"1989","unstructured":"Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., & Schopler, E. (1989). Autism Diagnostic Observation Schedule: A standardized observation of communicative and social behaviour. Journal of Autism and Developmental Disorders, 19185-212.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR18","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1007\/BF02172145","volume":"24","author":"C. Lord","year":"1994","unstructured":"Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24650-685.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF01531604","volume":"15","author":"C. Lord","year":"1985","unstructured":"Lord, C., & Schopler, E. (1985). Brief report: Differences in sex ratios in autism as a function of measured intelligence. Journal of Autism and Developmental Disorders, 15185-193.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR20","volume-title":"Classification of occupations and coding index","author":"Office of Population CensusesSurveys","year":"1980","unstructured":"Office of Population Censuses and Surveys (1980). Classification of occupations and coding index.London: HMSO."},{"key":"294530_CR21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1023\/A:1005113900068","volume":"28","author":"M. Rutter","year":"2000","unstructured":"Rutter, M. (2000). Genetic studies of autism: From the 1970s to the millennium. Journal of Abnormal Child Psychology, 283-14.","journal-title":"Journal of Abnormal Child Psychology"},{"key":"294530_CR22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1469-7610.1994.tb01164.x","volume":"33","author":"M. Rutter","year":"1994","unstructured":"Rutter, M., Bailey, A., Bolton, P., & Le Couteur, A. (1994). Autism and known medical conditions: Myth and substance. Journal of Child Psychology and Psychiatry, 33311-322.","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"294530_CR23","first-page":"370","volume-title":"Handbook of autism and pervasive developmental disorders","author":"M. Rutter","year":"1997","unstructured":"Rutter, M., Bailey, A., Simonoff, E., & Pickles, A. (1997). Genetic influences and autism. In D. Cohen & F. Volkmar (Eds.), Handbook of autism and pervasive developmental disorders(2nd ed., pp. 370-387). New York: Wiley.","edition":"2nd ed."},{"key":"294530_CR24","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1023\/A:1026052421693","volume":"28","author":"S. L. Smalley","year":"1998","unstructured":"Smalley, S. L. (1998). Autism and tuberous sclerosis. Journal of Autism and Developmental Disorders, 28407-414.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"294530_CR25","volume-title":"Vineland Adaptive Behavior Scale","author":"S. Sparrow","year":"1984","unstructured":"Sparrow, S., Balla, D., & Cicchetti, D. (1984). Vineland Adaptive Behavior Scale.Circle Pines, MN: American Guidance Services."},{"key":"294530_CR26","volume-title":"Stata Statistical Software: Release 5.0","author":"StataCorp.","year":"1997","unstructured":"StataCorp. (1997). Stata Statistical Software: Release 5.0.College Station, TX: Author."},{"key":"294530_CR27","volume-title":"Guide for administering the Merrill-Palmer Scale of Mental Tests","author":"R. Stutsman","year":"1948","unstructured":"Stutsman, R. (1948). Guide for administering the Merrill-Palmer Scale of Mental Tests.New York: Harcourt, Brace and World."},{"key":"294530_CR28","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1097\/00004583-199311000-00022","volume":"32","author":"P. Szatmari","year":"1993","unstructured":"Szatmari, P., Jones, M., Tuff, L., Bartolucci, G., Fisman, S., & Mahoney, W. (1993). Lack of cognitive impairment in first degree relatives of children with pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 321264-1273.","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"294530_CR29","volume-title":"Exceptional infant","author":"M. Waldrop","year":"1971","unstructured":"Waldrop, M., & Halverson, C. (1971). Minor physical anomalies and hyperactive behaviour in young children. In J. Hellmutt (Ed.), Exceptional infant.New York: Bruner\/Mazel."},{"key":"294530_CR30","volume-title":"ICD-10. Categories f00-f99 mental and behavioural disorders (including disorders of psychological development)","author":"World Health Organization.","year":"1992","unstructured":"World Health Organization. (1992). ICD-10. Categories f00-f99 mental and behavioural disorders (including disorders of psychological development).Clinical descriptions and diagnostic guidelines. Geneva: Author."}],"container-title":["Journal of Autism and Developmental Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005669915105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1005669915105\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005669915105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T08:30:09Z","timestamp":1749112209000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1005669915105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["294530"],"URL":"https:\/\/doi.org\/10.1023\/a:1005669915105","relation":{},"ISSN":["0162-3257","1573-3432"],"issn-type":[{"type":"print","value":"0162-3257"},{"type":"electronic","value":"1573-3432"}],"subject":[],"published":{"date-parts":[[2001,2]]}}}