{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T01:23:18Z","timestamp":1770427398786,"version":"3.49.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1023\/a:1006671804110","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T02:51:24Z","timestamp":1040525484000},"page":"294-305","source":"Crossref","is-referenced-by-count":21,"title":["The Mechanism of Mononuclear Cell Infiltration in Oral Lichen Planus: The Role of Cytokines Released from Keratinocytes"],"prefix":"10.1007","volume":"20","author":[{"given":"Tetsuya","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Nakane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokio","family":"Osaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"223929_CR1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S1079-2104(97)90244-4","volume":"83","author":"SR Porter","year":"1997","unstructured":"Porter SR, Kirby A, Olsen I, Barrett W: Immunologic aspects of dermal and oral lichen planus: A review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83:358-366, 1997","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"223929_CR2","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1177\/10454411980090010501","volume":"9","author":"C Scully","year":"1998","unstructured":"Scully C, Beyli M, Ferreiro MC, Ficarra G, Gill Y, Griffiths M, Holmstrup P, Mutlu S, Porter S, Wray D: Update on oral lichen planus: Etiopathogenesis and management. Crit Rev Oral Biol Med 9:86-122, 1998","journal-title":"Crit Rev Oral Biol Med"},{"key":"223929_CR3","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1600-0714.1990.tb00866.x","volume":"19","author":"LJ Walsh","year":"1990","unstructured":"Walsh LJ, Savage NW, Ishii T, Seymour GJ: Immunopathogenesis of oral lichen planus. J Oral Pathol Med 19:389-396, 1990","journal-title":"J Oral Pathol Med"},{"key":"223929_CR4","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1600-0714.1993.tb01056.x","volume":"22","author":"T Lombardi","year":"1993","unstructured":"Lombardi T, Hauser C, Budtz-J\u00f6rgensen E: Langerhans cells: Structure, function and role in oral pathological conditions. J Oral Pathol Med 22:193-202, 1993","journal-title":"J Oral Pathol Med"},{"key":"223929_CR5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/1523-1747.ep12523539","volume":"87","author":"T Shiohara","year":"1986","unstructured":"Shiohara T, Moriya N, Tsuchiya K, Nagashima M, Narimatsu H: Lichenoid tissue reaction induced by local transfer of la-reactive T-cell clones. J Invest Dermatol 87:33-38, 1986","journal-title":"J Invest Dermatol"},{"key":"223929_CR6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1601-0825.1996.tb00212.x","volume":"2","author":"A Pedersen","year":"1996","unstructured":"Pedersen A: Abnormal EBV immune status in oral lichen planus. Oral Dis 2:125-128, 1996","journal-title":"Oral Dis"},{"key":"223929_CR7","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/j.1600-0714.1997.tb00231.x","volume":"26","author":"J Laine","year":"1997","unstructured":"Laine J, Happonen RP, Vainio O, Kalimo K: In vitro lymphocyte proliferation test in the diagnosis of oral mucosal hypersensitivity reactions to dental amalgam. J Oral Pathol Med 26:362-366, 1997","journal-title":"J Oral Pathol Med"},{"key":"223929_CR8","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S0344-0338(89)80255-9","volume":"185","author":"J Hirota","year":"1989","unstructured":"Hirota J, Yoneda K, Osaki T: Destruction of basement membrane and cell infiltrates in oral lichen planus. Pathol Res Pract 185:218-224, 1989","journal-title":"Pathol Res Pract"},{"key":"223929_CR9","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0344-0338(11)80226-8","volume":"186","author":"J Hirota","year":"1990","unstructured":"Hirota J, Osaki T, Tatemoto Y: Immunohistochemical staining of infiltrates in oral lichen planus. Path Res Pract 186:625-632, 1990","journal-title":"Path Res Pract"},{"key":"223929_CR10","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0344-0338(11)81248-3","volume":"188","author":"J Hirota","year":"1992","unstructured":"Hirota J, Osaki T: Electron microscopic study on cell-to-cell interactions in oral lichen planus. Path Res Pract 188:1033-1041, 1992","journal-title":"Path Res Pract"},{"key":"223929_CR11","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/S1079-2104(05)80254-9","volume":"80","author":"TE Bramanti","year":"1995","unstructured":"Bramanti TE, Dekker NP, Lozada-Nur F, Sauk JJ, Regezi JA: Heat shock (stress) proteins and \u03b3\u03b4-T lymphocytes in oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80:698-704, 1995","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"223929_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0714.1995.tb01121.x","volume":"24","author":"PB Sugerman","year":"1995","unstructured":"Sugerman PB, Savage NW, Xu LJ, Walsh LJ, Seymour GJ: Heat shock protein expression in oral lichen planus. J Oral Pathol Med 24:1-8, 1995","journal-title":"J Oral Pathol Med"},{"key":"223929_CR13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1600-0714.1994.tb00067.x","volume":"23","author":"T Yamamoto","year":"1994","unstructured":"Yamamoto T, Osaki T, Yoneda K, Ueta E: Cytokine production by keratinocytes and mononuclear infiltrates in oral lichen planus. J Oral Pathol Med 23:309-315, 1994","journal-title":"J Oral Pathol Med"},{"key":"223929_CR14","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/1523-1747.ep12606990","volume":"104","author":"T Yamamoto","year":"1995","unstructured":"Yamamoto T, Osaki T: Characteristic cytokines generated by keratinocytes and mononuclear infiltrates in oral lichen planus. J Invest Dermatol 104:784-788, 1995","journal-title":"J Invest Dermatol"},{"key":"223929_CR15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1126\/science.7716514","volume":"268","author":"EA Clark","year":"1995","unstructured":"Clark EA, Brugge JJ: Integrins and signal transduction pathways: The road taken. Science 268:233-239, 1995","journal-title":"Science"},{"key":"223929_CR16","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1615\/CritRevImmunol.v15.i3-4.60","volume":"15","author":"D Hauzenberger","year":"1995","unstructured":"Hauzenberger D, Klominek J, Bergstrom SE, Sundqvist KG: T lymphocyte migration: The influence of interactions via adhesion molecules, the T cell receptor, and cytokines. Crit Rev Immunol 15:285-316, 1995","journal-title":"Crit Rev Immunol"},{"key":"223929_CR17","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1083\/jcb.131.3.791","volume":"131","author":"S Miyamoto","year":"1995","unstructured":"Miyamoto S, Teramoto H, Coso OA, Gutkind JS, Burbelo PD, Akiyama SK, Yamada KM: Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol 131:791-805, 1995","journal-title":"J Cell Biol"},{"key":"223929_CR18","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1600-0714.1990.tb00787.x","volume":"19","author":"U Konter","year":"1990","unstructured":"Konter U, Kellner I, Hoffmeister B, Sterry W: Induction and up-regulation of adhesion receptors in oral and dermal lichen planus. J Oral Pathol Med 19:459-463, 1990","journal-title":"J Oral Pathol Med"},{"key":"223929_CR19","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1601-0825.1996.tb00222.x","volume":"2","author":"V Ramirez-Amador","year":"1996","unstructured":"Ramirez-Amador V, Dekker NP, Lozada-Nur F, Mirowski GW, MacPhail LA, Regezi JA: Altered interface adhesion molecules in oral lichen planus. Oral Dis 2:188-192, 1996","journal-title":"Oral Dis"},{"key":"223929_CR20","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/S1079-2104(96)80074-6","volume":"81","author":"JA Regezi","year":"1996","unstructured":"Regezi JA, Dekker NP, MacPhail LA, Lozada-Nur F, McCalmont TH: Vascular adhesion molecules in oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81:682-690, 1996","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"223929_CR21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1126\/science.272.5258.60","volume":"272","author":"EC Butcher","year":"1996","unstructured":"Butcher EC, Picker LJ: Lymphocyte homing and homeostasis. Science 272:60-66, 1996","journal-title":"Science"},{"key":"223929_CR22","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0092-8674(00)81279-9","volume":"84","author":"BM Gumbiner","year":"1996","unstructured":"Gumbiner BM: Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84:345-357, 1996","journal-title":"Cell"},{"key":"223929_CR23","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/346425a0","volume":"346","author":"TA Springer","year":"1990","unstructured":"Springer TA: Adhesion receptors of the immune system. Nature 346:425-434, 1990","journal-title":"Nature"},{"key":"223929_CR24","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/(SICI)1521-4141(199801)28:01<104::AID-IMMU104>3.0.CO;2-F","volume":"28","author":"SJ Roth","year":"1998","unstructured":"Roth SJ, Diacova TG, Brenner MB, Rosat JP, Buccola J, Morita CT, Springer TA: Transendothelial chemotaxis of human \u03b1\/\u03b2 and \u03b3\/\u03b4 T lymphocytes to chemokines. Eur J Immunol 28:104-113, 1998","journal-title":"Eur J Immunol"},{"key":"223929_CR25","first-page":"439","volume":"60","author":"JM Wang","year":"1987","unstructured":"Wang JM, Colella S, Allavena P, Mantovani A: Chemotactic activity of human recombinant granulocyte-macrophage colonystimulating factor. Immunology 60:439-444, 1987","journal-title":"Immunology"},{"key":"223929_CR26","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0006-291X(89)91076-0","volume":"165","author":"KB Bacon","year":"1989","unstructured":"Bacon KB, Westwick J, Camp RDR: Potent and specific inhibition of IL-8-, IL-1 \u03b1-and IL-1 \u03b2-induced in vitro human lymphocyte migration by calcium channel antagonists. Biochem Biophys Res Commun 165:349-354, 1989","journal-title":"Biochem Biophys Res Commun"},{"key":"223929_CR27","first-page":"81","volume":"1072","author":"M Stoker","year":"1991","unstructured":"Stoker M, Gherardi E: Regulation of cell movement: The motogenic cytokines. Biochim Biophys Acta 1072:81-102, 1991","journal-title":"Biochim Biophys Acta"},{"key":"223929_CR28","doi-asserted-by":"crossref","first-page":"s22","DOI":"10.1007\/BF00638236","volume":"284","author":"JM Schr\u00f6der","year":"1992","unstructured":"Schr\u00f6der JM: Peptides and cytokines. Arch Dermatol Res 284:s22-26, 1992","journal-title":"Arch Dermatol Res"},{"key":"223929_CR29","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1600-0625.1992.tb00066.x","volume":"1","author":"JM Schr\u00f6der","year":"1992","unstructured":"Schr\u00f6der JM: Chemotactic cytokines in the epidermis. Exp Dermatol 1:12-19, 1992","journal-title":"Exp Dermatol"},{"key":"223929_CR30","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/1523-1747.ep12345482","volume":"106","author":"J Li","year":"1996","unstructured":"Li J, Ireland GW, Farthing PM, Thornhill MH: Epidermal and oral keratinocytes are induced to produce RANTES and IL-8 by cytokine stimulation. J Invest Dermatol 106:661-666, 1996","journal-title":"J Invest Dermatol"},{"key":"223929_CR31","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.4049\/jimmunol.148.8.2423","volume":"148","author":"Y Jiang","year":"1992","unstructured":"Jiang Y, Beller DI, Frendl G, Graves DT: Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J Immunol 148:2423-2428, 1992","journal-title":"J Immunol"},{"key":"223929_CR32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0167-5699(97)81662-3","volume":"18","author":"A Mantovani","year":"1997","unstructured":"Mantovani A, Bussolino F, Introna M: Cytokine regulation of endothelial cell function: From molecular level to the bedside. Immunol Today 18:231-240, 1997","journal-title":"Immunol Today"},{"key":"223929_CR33","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1093\/oxfordjournals.jbchem.a124451","volume":"115","author":"S Nakamura","year":"1994","unstructured":"Nakamura S, Nishizuka Y: Lipid mediators and protein kinase C activation for the intracellular signaling network. J Biochem 115:1029-1034, 1994","journal-title":"J Biochem"},{"key":"223929_CR34","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1126\/science.1411571","volume":"258","author":"Y Nishizuka","year":"1992","unstructured":"Nishizuka Y: Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614, 1992","journal-title":"Science"},{"key":"223929_CR35","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1084\/jem.175.4.1045","volume":"175","author":"Y Nojima","year":"1992","unstructured":"Nojima Y, Rothstein DM, Sugita K, Schlossman SF, Morimoto C: Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein. J Exp Med 175:1045-1053, 1992","journal-title":"J Exp Med"},{"key":"223929_CR36","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1182\/blood.V85.7.1858.bloodjournal8571858","volume":"85","author":"H Rabinowich","year":"1995","unstructured":"Rabinowich H, Lin WC, Manciulea M, Herberman RB, Whiteside TL: Induction of protein tyrosine phosphorylation in human natural killer cells by triggering via \u03b14\u03b21 or \u03b15\u03b21 integrins. Blood 85:1858-1864, 1995","journal-title":"Blood"},{"key":"223929_CR37","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.4049\/jimmunol.158.3.1061","volume":"158","author":"H Haller","year":"1997","unstructured":"Haller H, Kunzendorf U, Sacherer K, Lindschau C, Walz G, Distler A, Luft FC: T cell adhesion to P-selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates. J Immunol 158:1061-1067, 1997","journal-title":"J Immunol"},{"key":"223929_CR38","doi-asserted-by":"crossref","first-page":"10148","DOI":"10.1073\/pnas.91.21.10148","volume":"91","author":"HC Chen","year":"1994","unstructured":"Chen HC, Guan JL: Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 91:10148-10152, 1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"223929_CR39","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/372786a0","volume":"372","author":"DD Schlaepfer","year":"1994","unstructured":"Schlaepfer DD, Hanks SK, Hunter T, van der Geer P: Integrinmediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372:786-791, 1994","journal-title":"Nature"},{"key":"223929_CR40","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1074\/jbc.270.1.269","volume":"270","author":"N Morino","year":"1995","unstructured":"Morino N, Mimura T, Hamasaki K, Tobe K, Ueki K, Kikuchi K, Takehara K, Kadowaki T, Yazaki Y, Nojima Y: Matrix\/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2. J Biol Chem 270:269-273, 1995","journal-title":"J Biol Chem"},{"key":"223929_CR41","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.4049\/jimmunol.160.4.1901","volume":"160","author":"C Capodici","year":"1998","unstructured":"Capodici C, Hanft S, Feoktistov M, Pillinger MH: Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b\/CD18-dependent cell-cell adhesion of human neutrophils: Evidence for an ERK-independent pathway. J Immunol 160:1901-1909, 1998","journal-title":"J Immunol"},{"key":"223929_CR42","doi-asserted-by":"crossref","first-page":"4391","DOI":"10.1093\/emboj\/17.15.4391","volume":"17","author":"F Meng","year":"1998","unstructured":"Meng F, Lowell CA: A \u03b21 integrin-signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration. EMBO J 17:4391-4403, 1998","journal-title":"EMBO J"},{"key":"223929_CR43","doi-asserted-by":"crossref","first-page":"13223","DOI":"10.1074\/jbc.273.21.13223","volume":"273","author":"M Tsuda","year":"1998","unstructured":"Tsuda M, Matozaki T, Fukunaga K, Fujioka Y, Imamoto A, Noguchi T, Takada T, Yamao T, Takeda H, Ochi F, Yamamoto T, Kasuga M: Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. J Biol Chem 273:13223-13229, 1998","journal-title":"J Biol Chem"},{"key":"223929_CR44","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1083\/jcb.140.1.211","volume":"140","author":"LA Cary","year":"1998","unstructured":"Cary LA, Han DC, Polte TR, Hanks SK, Guan JL: Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration. J Cell Biol 140:211-221, 1998","journal-title":"J Cell Biol"},{"key":"223929_CR45","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.1128\/MCB.18.7.3936","volume":"18","author":"C D'Souza-Schorey","year":"1998","unstructured":"D'Souza-Schorey C, Boettner B, Van Aelst L: Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes. Mol Cell Biol 18:3936-3946, 1998","journal-title":"Mol Cell Biol"},{"key":"223929_CR46","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1128\/MCB.18.8.4744","volume":"18","author":"AD Ma","year":"1998","unstructured":"Ma AD, Metjian A, Bagrodia S, Taylor S, Abrams CS: Cytoskeletal reorganization by G protein-coupled receptors on phosphoinositide 3-kinase \u03b3, a Rac guanosine exchange factor, and Rac. Mol Cell Biol 18:4744-4751, 1998","journal-title":"Mol Cell Biol"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1006671804110.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1006671804110\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1006671804110.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T13:30:50Z","timestamp":1751031050000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1006671804110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["223929"],"URL":"https:\/\/doi.org\/10.1023\/a:1006671804110","relation":{},"ISSN":["0271-9142","1573-2592"],"issn-type":[{"value":"0271-9142","type":"print"},{"value":"1573-2592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}