{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:06:32Z","timestamp":1763035592302,"version":"3.41.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Immunol"],"published-print":{"date-parts":[[2000,1]]},"DOI":"10.1023\/a:1006686426090","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T02:51:24Z","timestamp":1040525484000},"page":"24-30","source":"Crossref","is-referenced-by-count":133,"title":["Autologous Stem Cell Transplantation in Progressive Multiple Sclerosis\u2014An Interim Analysis of Efficacy"],"prefix":"10.1007","volume":"20","author":[{"given":"A.","family":"Fassas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Anagnostopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kazis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Kapinas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Sakellari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Kimiskidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Smias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Eleftheriadis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Tsimourtou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"222066_CR1","first-page":"246","volume":"2","author":"JR Gulcher","year":"1994","unstructured":"Gulcher JR, Vartanian T, Stefansson K: Is multiple sclerosis an autoimmune disease? Clin Neurosci 2:246-252, 1994","journal-title":"Clin Neurosci"},{"key":"222066_CR2","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0167-5699(95)80176-6","volume":"16","author":"R Hohlfeld","year":"1995","unstructured":"Hohlfeld R, Londi M, Massacesi L, Salvetti M: T-cell immunity in multiple sclerosis. Immunol Today 16:259-261, 1995","journal-title":"Immunol Today"},{"key":"222066_CR3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1046\/j.1365-2141.1997.3273144.x","volume":"99","author":"JA Snowden","year":"1997","unstructured":"Snowden JA, Brooks PM, Biggs JC: Haemopoietic stem cell transplantation for autoimmune diseases. Br J Haematol 99:9-22, 1997","journal-title":"Br J Haematol"},{"key":"222066_CR4","first-page":"139","volume-title":"McAlpine's Multiple Sclerosis","author":"WB Matthews","year":"1991","unstructured":"Matthews WB: Course and prognosis. In McAlpine's Multiple Sclerosis, WB Matthews, A Compston, IV Allen, CN Martyn (eds). Singapore, Churchill Livingstone, 1991, pp. 139-163"},{"key":"222066_CR5","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1056\/NEJM199711273372207","volume":"337","author":"RA Rudick","year":"1997","unstructured":"Rudick RA, Cohen JA, Weinstock-Guttman B, Kinkel RP, Ransohoff RM: Management of multiple sclerosis. New Engl J Med 337:1604-1611, 1997","journal-title":"New Engl J Med"},{"key":"222066_CR6","first-page":"497","volume":"16","author":"AM Marmont","year":"1995","unstructured":"Marmont AM, van Bekkum DW: Stem cell transplantation for severe autoimmune diseases. Bone Marrow Transplant 16:497-498, 1995","journal-title":"Bone Marrow Transplant"},{"key":"222066_CR7","first-page":"733","volume":"83","author":"AM Marmont","year":"1998","unstructured":"Marmont AM: Stem cell transplantation for severe autoimmune diseases: Progress and problems. Haematologica 83:733-743, 1998","journal-title":"Haematologica"},{"key":"222066_CR8","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1002\/stem.140460","volume":"14","author":"DW van Bekkum","year":"1996","unstructured":"van Bekkum DW, Marmont AM, Tyndall A, Vriesendorp FJ, Apatoff BJ, Rowlings PA: Severe autoimmune diseases: A new target for bone marrow transplantation. Stem cells 14:460-472, 1996","journal-title":"Stem cells"},{"key":"222066_CR9","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/sj.bmt.1700666","volume":"19","author":"LD McAllister","year":"1997","unstructured":"McAllister LD, Beatty PG, Rose J: Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis. Bone Marrow Transplant 19:395-397, 1997","journal-title":"Bone Marrow Transplant"},{"key":"222066_CR10","first-page":"467","volume":"14","author":"BR Apatoff","year":"1996","unstructured":"Apatoff BR: Stem cell transplantation in the treatment of multiple sclerosis. Stem Cells 14:467-472, 1996","journal-title":"Stem Cells"},{"key":"222066_CR11","first-page":"1029","volume":"18","author":"M van Gelder","year":"1996","unstructured":"van Gelder M, van Bekkum DW: Effective treatment of relapsing experimental autoimmune encephalomyelitis with pseudoautologous bone marrow transplantation. Bone Marrow Transplant 18: 1029-1034, 1996","journal-title":"Bone Marrow Transplant"},{"key":"222066_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/clin.1998.4563","volume":"89","author":"DW van Bekkum","year":"1998","unstructured":"van Bekkum DW: New opportunities for the treatment of severe autoimmune diseases: Bone marrow transplantation. Clin Immunol Immunopathol 89:1-10, 1998","journal-title":"Clin Immunol Immunopathol"},{"key":"222066_CR13","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1172\/JCI116648","volume":"92","author":"DM Karussis","year":"1993","unstructured":"Karussis DM, Vourka-Karussis U, Lehmann D, Ovadia H, Mizrachi-Koll R, Ben-Nun A, Abramsky O, Slavin S: Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation. J Clin Invest 92:765-772, 1993","journal-title":"J Clin Invest"},{"key":"222066_CR14","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/sj.bmt.1700944","volume":"20","author":"A Fassas","year":"1997","unstructured":"Fassas A, Anagnostopoulos A, Kazis A, Kapinas A, Sakellari I, Kimiskidis V, Tsompanakou A: Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: First results of a pilot study. Bone Marrow Transplant 20:631-638, 1997","journal-title":"Bone Marrow Transplant"},{"key":"222066_CR15","first-page":"452","volume-title":"Autologous Blood and Marrow Transplantation\u2014Proceedings of the Ninth International Symposium, Arlington, Texas","author":"A Fassas","year":"1999","unstructured":"Fassas A, Anagnostopoulos A, Kazis A, Kapinas K, Sakellari I, Kimiskidis V, Yannaki E: Autologous blood stem cell therapy for progressive multiple sclerosis. In Autologous Blood and Marrow Transplantation\u2014Proceedings of the Ninth International Symposium, Arlington, Texas, KA Dicke, A Keating (eds). Charlottesville, Carden Jennings, 1999, pp 452-463"},{"key":"222066_CR16","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1212\/WNL.33.11.1444","volume":"33","author":"JF Kurtzke","year":"1983","unstructured":"Kurtzke JF: Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 33:1444-1452, 1983","journal-title":"Neurology"},{"key":"222066_CR17","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/sj.bmt.1700727","volume":"19","author":"A Tyndall","year":"1997","unstructured":"Tyndall A, Gratwohl A: Blood and marrow stem cell transplants in autoimmune disease: A consensus report written on behalf of the European League against Rheumatism (EULAR) and the European Group for Blood and Marrow transplantation (EBMT). Bone Marrow Transplant 19:643-645, 1997","journal-title":"Bone Marrow Transplant"},{"key":"222066_CR18","unstructured":"Comi G, Kappos L, Clanet M, Ebers G, Fassas A, Fazekas F, Filippi M, Hartung HP, Martino G, Tyndall A, van der Meche FGA, BMT-MS Study Group: guidelines for blood and marrow stem cell transplantation in multiple sclerosis. J Neurology (in press)"},{"key":"222066_CR19","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1212\/WNL.46.6.1613","volume":"46","author":"G Weinshenker","year":"1996","unstructured":"Weinshenker G, Issa M, Baskerville J: Meta-analysis of the placebo-treated groups in clinical trials of progressive MS. Neurology 46:1613-1619, 1996","journal-title":"Neurology"},{"key":"222066_CR20","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0140-6736(98)10039-9","volume":"352","author":"European Study Group on Interferon \u03b2-1b in Secondary Progressive MS","year":"1998","unstructured":"European Study Group on Interferon \u03b2-1b in Secondary Progressive MS: Placebo-controlled multicentre randomised trial of interferon \u03b2-1b in treatment of secondary progressive multiple sclerosis. Lancet 352:1491-1497, 1998","journal-title":"Lancet"},{"key":"222066_CR21","first-page":"1274","volume":"25","author":"S Slavin","year":"1993","unstructured":"Slavin S, Karussis D, Weiss L, Vourka-Karoussis U, Abramsky O: Immunohematopoietic reconstitution by allogeneic and autologous bone marrow grafts as a means for induction of specific unresponsiveness to donor-specific allografts and modified self in autoimmune disorders. Transplant Proc 25:1274-1275, 1993","journal-title":"Transplant Proc"},{"key":"222066_CR22","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1097\/00002281-199905000-00003","volume":"11","author":"JA Snowden","year":"1999","unstructured":"Snowden JA, Brooks PM: Hematopoietic stem cell transplantation in rheumatic diseases. Current Opinion Rheumatol 11:167-172, 1999","journal-title":"Current Opinion Rheumatol"},{"key":"222066_CR23","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/sj.bmt.1701129","volume":"21","author":"RK Burt","year":"1998","unstructured":"Burt RK, Traynor AE, Cohen B, Karlin KH, Davis FA, Stefoski D, Terry C, Lobeck L, Russel EJ, Goolsby C, Rosen S, Gordon LI, Keever-Taylor C, Brush M, Fishman M, Burns WH: T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report on the first three patients. Bone Marrow Transplant 21:537-541, 1998","journal-title":"Bone Marrow Transplant"},{"key":"222066_CR24","doi-asserted-by":"crossref","first-page":"3505","DOI":"10.1182\/blood.V92.10.3505","volume":"92","author":"RK Burt","year":"1998","unstructured":"Burt RK, Traynor AE, Pope R, Schroeder J, Cohen B, Karlin KH, Lobeck L, Goolsby C, Rowlings P, Davis FA, Stefoski D, Terry C, Keever-Taylor C, Rosen S, Vesole D, Fishman M, Brush M, Mujias S, Villa M, Burns WH: Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation. Blood 92:3505-3514, 1998","journal-title":"Blood"},{"key":"222066_CR25","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.7326\/0003-4819-129-12-199812150-00007","volume":"129","author":"RA Brodsky","year":"1998","unstructured":"Brodsky RA, Petri M, Smith BD, Seifter EJ, Spivak JL, Styler M, Dang CV, Brodsky I, Jones RJ: Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease. Ann Intern Med 129:1031-1035, 1998","journal-title":"Ann Intern Med"}],"container-title":["Journal of Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1006686426090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1006686426090\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1006686426090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T13:25:48Z","timestamp":1751030748000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1006686426090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["222066"],"URL":"https:\/\/doi.org\/10.1023\/a:1006686426090","relation":{},"ISSN":["0271-9142","1573-2592"],"issn-type":[{"type":"print","value":"0271-9142"},{"type":"electronic","value":"1573-2592"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}