{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T16:35:58Z","timestamp":1765038958077,"version":"3.41.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2001,2]]},"DOI":"10.1023\/a:1007023611478","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T08:59:48Z","timestamp":1040547588000},"page":"33-45","source":"Crossref","is-referenced-by-count":55,"title":["Pattern of Cytokine and Adhesion Molecule mRNA in Hapten-Induced Relapsing Colon Inflammation in the Rat"],"prefix":"10.1007","volume":"25","author":[{"given":"Frank F.","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pi-Shiang","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Yue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kingsley","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert G.","family":"Nagele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald M.","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond F.","family":"Krzesicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia En","family":"Chin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick Y.-K.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"226650_CR1","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S0025-7125(16)30096-7","volume":"78","author":"R. P. MacDermott","year":"1994","unstructured":"MacDermott, R. P. 1994. Alterations in the mucosal immune system in ulcerative colitis and Crohn's disease. Medical Clinics of North America\n78:1207\u20131232.","journal-title":"Medical Clinics of North America"},{"key":"226650_CR2","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1023\/A:1018895500721","volume":"42","author":"S. Dionne","year":"1997","unstructured":"Dionne, S., J. Hiscott, I. D'Agata, A. Duhaime, and E. G. Seidman. 1997. Quantitative PCR analysis of TNF-\u03b1 and IL-1\u03b2 mRNA levels in pediatric IBD mucosal biopsies. Dig. Dis. Sci.\n42:1557\u20131566.","journal-title":"Dig. Dis. Sci."},{"key":"226650_CR3","first-page":"5S","volume":"92","author":"R. B. Sartor","year":"1997","unstructured":"Sartor, R. B. 1997. Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases. Am. J. Grastroenterol.\n92:5S\u201311S.","journal-title":"Am. J. Grastroenterol."},{"key":"226650_CR4","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0167-5699(97)01000-1","volume":"18","author":"W. Strober","year":"1997","unstructured":"Strober, W., B. Kelsall, I. J. Fuss, T. Marth, B. Ludviksson, R. Ehrhardt, and M. Neurath. 1997. Reciprocal IFN-\u03b3 and TGF\u03b2 responses regulate the occurrence of mucosal inflammation. Immunol. Today\n18:61\u201364.","journal-title":"Immunol. Today"},{"key":"226650_CR5","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1007\/BF02285198","volume":"40","author":"K. Fukushima","year":"1995","unstructured":"Fukushima, K., G. West, and C. Fiocchi. 1995. Adequacy of mucosal biopsies for evaluation of intestinal cytokine specific mRNA. Dig. Dis. Sci.\n40:1498\u20131505.","journal-title":"Dig. Dis. Sci."},{"key":"226650_CR6","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-2249.1995.tb03130.x","volume":"101","author":"M. Niessner","year":"1995","unstructured":"Niessner, M., and B. A. Volk. 1995. Altered Th1\/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR). Clin. Exp. Immunol.\n101:428\u2013435.","journal-title":"Clin. Exp. Immunol."},{"key":"226650_CR7","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.4049\/jimmunol.157.3.1261","volume":"157","author":"I. J. Fuss","year":"1996","unstructured":"Fuss, I. J., M. Neurath, M. Boirivant, J. S. Klein, C. De La Motte, S. A. Strong, C. Fiocchi, and W. Strober. 1996. Disparate CD4+ lamina propria lymphokine secretion profiles in inflammatory bowel disease. J. Immunol.\n157:1261\u20131270.","journal-title":"J. Immunol."},{"key":"226650_CR8","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0022-3565(25)10653-8","volume":"274","author":"P. Y. K. Wong","year":"1995","unstructured":"Wong, P. Y. K., G. Yue, K. Yin, M. Miyasaka, C. L. Lane, A. M. Manning, D. C. Anderson, and F. F. Sun. 1995. Antibodies to ICAM-1 ameliorate the inflammatory response in acetic acid induced inflammatory bowel disease. J. Pharmacol. Exptl. Therap.\n274:475\u2013480.","journal-title":"J. Pharmacol. Exptl. Therap."},{"key":"226650_CR9","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/0016-5085(95)90599-5","volume":"109","author":"C. O. Elson","year":"1995","unstructured":"Elson, C. O., R. B. Sartor, G. S. Tennyson, and R. H. Riddell. 1995. Experimental models of inflammatory bowel disease. Gastroenterol. 109:1344\u20131367.","journal-title":"Gastroenterol"},{"key":"226650_CR10","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1084\/jem.178.1.237","volume":"178","author":"P. J. Morrissey","year":"1993","unstructured":"Morrissey, P. J., K. Charrier, S. Braddy, D. Liggitt, and R. L. Coffman. 1993. CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice: disease development is prevented by cotransfer of purified CD4+ T cells. J. Exp. Med.\n178:237\u2013241.","journal-title":"J. Exp. Med."},{"key":"226650_CR11","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0022-3565(25)12260-X","volume":"276","author":"G. Yue","year":"1996","unstructured":"Yue, G., F. F. Sun, C. J. Dunn, K. Yin, and P. Y.-K. Wong. 1996. The 21-aminosteroid tirilazad mesylate ameliorate inflammatory bowel disease (IBD) in rats. J. Pharm. Exptl. Therap.\n276:265\u2013269.","journal-title":"J. Pharm. Exptl. Therap."},{"key":"226650_CR12","first-page":"G119","volume":"269","author":"C. B. Appleyard","year":"1995","unstructured":"Appleyard, C. B., and J. L. Wallace. 1995. Reactivation of hapteninduced colitis and its prevention by anti-inflammatory drugs. Amer. J. Physiol.\n269:G119\u2013G125.","journal-title":"Amer. J. Physiol."},{"key":"226650_CR13","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/1523-1747.ep12506462","volume":"78","author":"P. P. Bradley","year":"1982","unstructured":"Bradley, P. P., D. A. Priebat, R. D. Christensen, and G. Rothstein. 1982. Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J. Invest Dermatol.\n78:206\u2013209.","journal-title":"J. Invest Dermatol."},{"key":"226650_CR14","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1165\/ajrcmb.16.6.9191471","volume":"16","author":"R. F. Krzesicki","year":"1997","unstructured":"Krzesicki, R. F., G. E. Winterrowd, J. R. Brashler, C. A. Hat-field, R. L. Griffin, S. F. Fidler, K. P. Kolbasa, K. L. Shull, I. M. Richards, and J. E. Chin. 1997. Identification of cytokine and adhesion molecule mRNA in murine lung tissue and isolated T cells and eosinophils by semi-quantitative reverse transcriptase-polymerase chain reaction. Am. J. Respir. Cell Mol. Biol.\n16:693\u2013701.","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"226650_CR15","doi-asserted-by":"crossref","first-page":"G130","DOI":"10.1152\/ajpcell.1996.271.1.C130","volume":"271","author":"L. A. Dieleman","year":"1996","unstructured":"Dieleman, L. A., C. O. Elson, G. S. Tennyson, and K. W. Beagley. 1996. Kinetics of cytokine expression during healing of acute colitis in mice. Amer. J. Physiol.\n271:G130\u2013G136.","journal-title":"Amer. J. Physiol."},{"key":"226650_CR16","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1002\/eji.1830270722","volume":"27","author":"M. F. Neurath","year":"1997","unstructured":"Neurath, M. F., I. J., Fuss, M. Pasparakis, L. Alexopouloum, L. Haralambous, K. H. Meyer Zum Buschenfelde, W. Strober, and G. Kollias. 1997. Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice. Europ. J. Immunol.\n27:1743\u20131750.","journal-title":"Europ. J. Immunol."},{"key":"226650_CR17","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1136\/gut.41.5.651","volume":"41","author":"T. Andus","year":"1997","unstructured":"Andus, T., R. Daig, D. Vogl, E. Aschenbrenner, G. Lock, S. Hollerbach, M. Kollinger, J. Scholmerich, and V. Gross. 1997. Imbalance of the interleukin 1 system in colonic mucosa-association with intestinal inflammation and interleukin 1 receptor agonist genotype 2, Gut\n41:651\u2013657.","journal-title":"Gut"},{"key":"226650_CR18","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.3109\/00365529709011220","volume":"32","author":"O. H. Nielsen","year":"1997","unstructured":"Nielsen, O. H., N. Rudiger, M. Gaustadnes, and T. Horn. 1997. Intestinal interleukin-8 concentration and gene expression in inflammatory bowel disease. Scand. J. Gastroenterology\n32:1028\u20131034.","journal-title":"Scand. J. Gastroenterology"},{"key":"226650_CR19","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0016-5085(95)90006-3","volume":"108","author":"H. C. Reinecker","year":"1995","unstructured":"Reinecker, H. C., E. Y. Loh, D. J. Ringler, A. Mehta, J. L. Rombeau, and R. P. MacDermott. 1995. Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterol.\n108:40\u201350.","journal-title":"Gastroenterol."},{"key":"226650_CR20","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1084\/jem.182.5.1281","volume":"182","author":"M. F. Neurath","year":"1995","unstructured":"Neurath, M. F., I. J. Fuss, B. L. Kelsall, E. Stuber, and W. Strober. 1995. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J. Exptl. Med.\n182:1281\u20131290.","journal-title":"J. Exptl. Med."},{"issue":"8","key":"226650_CR21","first-page":"52","volume":"30","author":"M. Noguchi","year":"1995","unstructured":"Noguchi, M., N. Hiwatashi, Z. Liu, and T. Toyota. 1995. Enhanced interferon-g production and B7-2 expression in isolated intestinal mononuclear cells from patients with Crohn's disease. J. Gastroenterol.\n30 Suppl 8, 52\u201355.","journal-title":"J. Gastroenterol."},{"key":"226650_CR22","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/S0016-5085(97)70128-8","volume":"112","author":"G. Monteleone","year":"1997","unstructured":"Monteleone, G., L. Biancone, R. Marasco, G. Morrone, O. Marasco, F. Luzza, and F. Pallone. 1997. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterol.\n112:1169\u20131178.","journal-title":"Gastroenterol."},{"key":"226650_CR23","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1053\/gast.1996.v110.pm8613031","volume":"110","author":"M. W. Babyatsky","year":"1996","unstructured":"Babyatsky, M. W., G. Rossiter, and D. K. Podolsky. 1996. Expression of transforming growth factors a and b in colonic mucosa in inflammatory bowel disease. Gastroenterol.\n110:975\u2013984.","journal-title":"Gastroenterol."},{"key":"226650_CR24","first-page":"89","volume":"314","author":"A. A. Adjei","year":"1997","unstructured":"Adjei, A. A., C. K. Ameho, E. K. Harrison, K. Yamauchi, A. Kulkarni, A. Kawajiri, and S. Yamamoto. 1997. Nucleosidenucleotide-free diet suppresses cytokine production and contact sensitivity responses in rats with trinitrobenzene sulphonic acidinduced colitis. Amer. J. Med. Sci.\n314:89\u201396.","journal-title":"Amer. J. Med. Sci."},{"key":"226650_CR25","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1172\/JCI119823","volume":"100","author":"C. M. Hogaboam","year":"1997","unstructured":"Hogaboam, C. M., B. A. Vallance, A. Kumar, C. L. Addison, F. L. Graham, J. Gauldie, and S. M. Collins. 1997. Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease. J. Clin. Invest.\n100:2766\u20132776.","journal-title":"J. Clin. Invest."},{"key":"226650_CR26","first-page":"77","volume":"69","author":"S. Nakamura","year":"1993","unstructured":"Nakamura, S., H. Ohtani, Y. Watanabe, K. Fukushima, T. Matsumoto, A. Kitano, K. Kobayashi, and H. Nagura. 1993. In situ Expression of the cell adhesion molecules in inflammatory bowel disease. Lab. Invest.\n69:77\u201385.","journal-title":"Lab. Invest."},{"key":"226650_CR27","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/gut.36.3.411","volume":"36","author":"G. M. Schurmann","year":"1995","unstructured":"Schurmann, G. M., A. E. Bishop, P. Facer, M. Vecchio, J. C. Lee, D. S. Rampton, and J. M. Polak. 1995. Increased expression of cell adhesion molecule P-selectin in active inflammatory bowel disease. Gut\n36:411\u2013418.","journal-title":"Gut"},{"key":"226650_CR28","first-page":"97","volume":"151","author":"M. J. Briskin","year":"1997","unstructured":"Briskin, M. J., D. Winsor-Hines, A. Shyjan, N. Cochran, S. Bloom, J. Wilson, L. M. McEvoy, E. C. Butcher, N. Kassam, C. R. MacKay, W. Newman, and D. J. Ringler. 1997. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Amer. J. Pathol.\n151:97\u2013110.","journal-title":"Amer. J. Pathol."}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1007023611478.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1007023611478\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1007023611478.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T12:51:47Z","timestamp":1748263907000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1007023611478"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["226650"],"URL":"https:\/\/doi.org\/10.1023\/a:1007023611478","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"type":"print","value":"0360-3997"},{"type":"electronic","value":"1573-2576"}],"subject":[],"published":{"date-parts":[[2001,2]]}}}