{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T04:22:30Z","timestamp":1747801350400,"version":"3.41.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2000,11]]},"DOI":"10.1023\/a:1007180800941","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T09:07:15Z","timestamp":1040548035000},"page":"15-22","source":"Crossref","is-referenced-by-count":4,"title":["Lysosome lipid storage disorder in NCTR-BALB\/c mice: Spleen and lung lysosomes store unesterified cholesterol but differ in their phospholipid composition"],"prefix":"10.1007","volume":"214","author":[{"given":"Chidambaram","family":"Bhuvaneswaran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manford D.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"276503_CR1","first-page":"265","volume":"62","author":"C Bhuvaneswaran","year":"1980","unstructured":"Bhuvaneswaran C, Fowler S, Morris M: Free cholesterol storage disease: A new lysosomal disorder. Circulation 62: 265, 1980","journal-title":"Circulation"},{"key":"276503_CR2","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0005-2760(80)90116-2","volume":"619","author":"PG Pentchev","year":"1980","unstructured":"Pentchev PG, Gal AE, Booth AD, Omodeo-Sale F, Fowles J, Neumeyer BA, Quirk JM, Dawson G, Brady RO: A lysosomal storage disorder in mice characterized by a dual deficiency of sphingomyelinase and glucocerebrosidase. Biochim Biophys Acta 619: 669\u2013679, 1980","journal-title":"Biochim Biophys Acta"},{"key":"276503_CR3","first-page":"225","volume":"16","author":"PG Pentchev","year":"1980","unstructured":"Pentchev PG, Gal AE, Boothe AD, Fouks J, Omodeo-Sale F, Brady RO: A lysosomal storage disorder in mice characterized by the accumulation of several sphingolipids. Birth Defects: Original Article Series 16: 225\u2013230, 1980","journal-title":"Birth Defects: Original Article Series"},{"key":"276503_CR4","first-page":"140","volume":"108","author":"MD Morris","year":"1982","unstructured":"Morris MD, Bhuvaneswaran C, Shio H, Fowler S: Lysosome lipid storage disorder in NCTR-BALB\/c mice. I. Description of the disease and genetics. Am J Pathol 108: 140\u2013149, 1982","journal-title":"Am J Pathol"},{"key":"276503_CR5","first-page":"150","volume":"108","author":"S Shio","year":"1982","unstructured":"Shio S, Fowler S, Bhuvaneswaran C, Morris MD: Lysosome lipid storage disorder in NCTR-BALB\/c mice. II. Morphologic and cytochemical studies. Am J Pathol 108: 150\u2013159, 1982","journal-title":"Am J Pathol"},{"key":"276503_CR6","first-page":"160","volume":"108","author":"C Bhuvaneswaran","year":"1982","unstructured":"Bhuvaneswaran C, Morris MD, Shio H, Fowler S: Lysosome lipid storage disorder in NCTR-BALB\/c mice. III. Isolation and analysis of storage inclusions from liver. Am J Pathol 108: 160\u2013170, 1982","journal-title":"Am J Pathol"},{"key":"276503_CR7","doi-asserted-by":"crossref","first-page":"5784","DOI":"10.1016\/S0021-9258(18)91082-3","volume":"259","author":"PG Pentchev","year":"1984","unstructured":"Pentchev PG, Booth AD, Kurth HS, Weintraub H, Brady RO: A genetic storage disorder in Balb\/c mice with a metabolic block in the esterification of exogenously derived cholesterol. J Biol Chem 259: 5784\u20135791, 1984","journal-title":"J Biol Chem"},{"key":"276503_CR8","doi-asserted-by":"crossref","first-page":"2772","DOI":"10.1016\/S0021-9258(17)35852-0","volume":"261","author":"PG Pentchev","year":"1986","unstructured":"Pentchev PG, Comly ME, Kurth HS, Patel S, Proestel M, Weintroub H: The cholesterol storage disorder of the mutant Balb\/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease. J Biol Chem 261: 2772\u20132777, 1986","journal-title":"J Biol Chem"},{"key":"276503_CR9","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.nu.09.070189.002143","volume":"9","author":"SC Patel","year":"1989","unstructured":"Patel SC, Pentchev PG: Genetic Defects of lysosomal function in animals. Annu Rev Nutr 9: 395\u2013416, 1989","journal-title":"Annu Rev Nutr"},{"key":"276503_CR10","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1006\/bbrc.1993.2228","volume":"196","author":"JD Butler","year":"1993","unstructured":"Butler JD, Vanier MT, Pentchev PG: Niemann-Pick C disease: Cystine and lipids accumulate in the murine model of this lysosomal cholesterol lipidosis. Biochem Biophys Res Commun196: 154\u2013159, 1993","journal-title":"Biochem Biophys Res Commun"},{"key":"276503_CR11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF00203741","volume":"427","author":"T Manabe","year":"1995","unstructured":"Manabe T, Yamane T, Higashi Y, Pentchev PG, Suzuki K: Ultrastructural changes in the lung in Niemann-Pick type C mouse. Virchows Arch 427: 77\u201383, 1995","journal-title":"Virchows Arch"},{"key":"276503_CR12","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0304-4157(87)90013-X","volume":"906","author":"MC Phillips","year":"1987","unstructured":"Phillips MC, Johnson WJ, Rothblat GH: Mechanism and consequences of cellular cholesterol exchange and transfer. Biochim Biophys Acta 906: 223\u2013276, 1987","journal-title":"Biochim Biophys Acta"},{"key":"276503_CR13","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1111\/j.1471-4159.1985.tb04044.x","volume":"45","author":"H Weintraub","year":"1985","unstructured":"Weintraub H, Abramovici A, Sandbank U, Pentchev PG, Brady RO, Sekine M, Suzuki A, Sela B: Neurological mutation characterized by dysmyelination in NCTR-BALB\/c mouse with lysosomal lipid storage disease. J Neurochem 45: 665\u2013672, 1985","journal-title":"J Neurochem"},{"key":"276503_CR14","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1046\/j.1471-4159.1995.65020670.x","volume":"65","author":"S Schedin","year":"1995","unstructured":"Schedin S, Pentchev PG, Brunk U, Dallner G: Changes in the levels of dolichol and dolichyl phosphate in a murine model of Niemann-Pick type C disease. J Neurochem 65: 670\u2013676, 1995","journal-title":"J Neurochem"},{"key":"276503_CR15","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0022-2275(20)37817-2","volume":"25","author":"S Nakashima","year":"1984","unstructured":"Nakashima S, Nagata K, Banno Y, Sakiyama T, Kitagawa T, Miyawaki S, Nozawa Y: A mouse model for Niemann-Pick disease: Phospholipid class and fatty acid composition of various tissues. J Lipid Res 25: 219\u2013227, 1984","journal-title":"J Lipid Res"},{"key":"276503_CR16","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF00173309","volume":"174","author":"R. O. Kumar","year":"1996","unstructured":"Kumar RK, O'Grady R, Di Girolamo N: Epidermal growth factor-like molecular species in normal bronchoalveolar lavage fluid. Lung 174: 171\u2013179, 1996","journal-title":"Lung"},{"key":"276503_CR17","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1083\/jcb.32.2.339","volume":"32","author":"WE Bowers","year":"1967","unstructured":"Bowers WE, de Duve C: Lysosomes in lymphoid tissue. II. Intracellular distribution of acid hydrolases. J Cell Biol 32: 339\u2013348, 1967","journal-title":"J Cell Biol"},{"key":"276503_CR18","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/S0022-2275(20)36896-6","volume":"14","author":"LL Rudel","year":"1973","unstructured":"Rudel LL, Morris MD: Determination of cholesterol using ophthalaldehyde. J Lipid Res 14: 364\u2013366, 1973","journal-title":"J Lipid Res"},{"key":"276503_CR19","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","volume":"226","author":"J Folch","year":"1957","unstructured":"Folch J, Lees M, Sloane-Stanley GH: A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497\u2013509, 1957","journal-title":"J Biol Chem"},{"key":"276503_CR20","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0021-9258(18)84756-1","volume":"66","author":"CH Fiske","year":"1925","unstructured":"Fiske CH, Subbarow Y: The colorimetric determination of phosphorus. J Biol Chem 66: 375\u2013400, 1925","journal-title":"J Biol Chem"},{"key":"276503_CR21","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0003-2697(78)90278-6","volume":"85","author":"WT Coakley","year":"1978","unstructured":"Coakley WT, James CJ: A simple linear transform for the Folin-Lowry protein calibration curve to 1.0 mg\/ml. Anal Biochem 85: 90\u201397, 1978","journal-title":"Anal Biochem"},{"key":"276503_CR22","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1042\/bj0510223","volume":"51","author":"PG Walker","year":"1952","unstructured":"Walker PG: The preparation and properties of \u03b2-glucuronidase: 3. Fractionation and activity of homogenate in isotonic media. Biochem J 51: 223\u2013232, 1952","journal-title":"Biochem J"},{"key":"276503_CR23","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/0014-4827(61)90280-4","volume":"25","author":"K Paigen","year":"1961","unstructured":"Paigen K: The effect of mutation on the intracellular location of \u03b2-glucuronidase. Exp Cell Res 25: 286\u2013301, 1961","journal-title":"Exp Cell Res"},{"key":"276503_CR24","first-page":"235","volume":"33","author":"BM Loffler","year":"1994","unstructured":"Loffler BM, Mielenz E, Kunze H: Heterogeneity of Wistar rats with respect to acid beta-d-glucuronidase (EC 3.2.1.31) in liver. Biochem Mol Biol Int 33: 235\u2013244, 1994","journal-title":"Biochem Mol Biol Int"},{"key":"276503_CR25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0005-2744(75)90292-2","volume":"377","author":"W Colilla","year":"1975","unstructured":"Colilla W, Jorgenson RA, Nordlie RC: Mammalian carbamyl phosphate: Glucose phosphotransferase and glucose-6-phosphate phosphohydrolase: Extended tissue distribution. Biochim Biophys Acta 377: 117\u2013125, 1975","journal-title":"Biochim Biophys Acta"},{"key":"276503_CR26","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/0005-2744(72)90357-9","volume":"268","author":"BO De Lumen","year":"1972","unstructured":"De Lumen BO, Taylor S, Urribarri N, Tappel AL: Subcellular localization of acid hydrolases in rat lungs. Biochim Biophys Acta 268: 597\u2013600, 1972","journal-title":"Biochim Biophys Acta"},{"key":"276503_CR27","doi-asserted-by":"crossref","first-page":"12849","DOI":"10.1016\/S0021-9258(18)37638-5","volume":"263","author":"C Bublitz","year":"1988","unstructured":"Bublitz C, Steavenson S: The pentose phosphate pathway in the endoplasmic reticulum. J Biol Chem 263: 12849\u201312853, 1988","journal-title":"J Biol Chem"},{"key":"276503_CR28","doi-asserted-by":"crossref","first-page":"17018","DOI":"10.1074\/jbc.272.27.17018","volume":"272","author":"Y Lange","year":"1997","unstructured":"Lange Y, Ye J, Chin J: The fate of cholesterol exiting lysosomes. J Biol Chem 272: 17018\u201317022, 1997","journal-title":"J Biol Chem"},{"key":"276503_CR29","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/978-1-4615-5901-6_9","volume":"28","author":"WJ Johnson","year":"1997","unstructured":"Johnson WJ, Phillips MC, Rothblat GH: Lipoproteins and cellular cholesterol homeostasis. Subcell Biochem 28: 235\u2013276, 1997","journal-title":"Subcell Biochem"},{"key":"276503_CR30","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0009-3084(85)90019-2","volume":"38","author":"TJ Scallen","year":"1985","unstructured":"Scallen TJ, Pastuszyn A, Noland BJ, Chanderbhan R, Kharroubi A, Vahouny GV: Sterol carrier and lipid transfer proteins. Chem Phys Lipids 38: 239\u2013261, 1985","journal-title":"Chem Phys Lipids"},{"key":"276503_CR31","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1126\/science.277.5323.228","volume":"277","author":"ED Carstea","year":"1997","unstructured":"Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, Cummings C, Gu J, Rosenfeld MA, Pavan WJ, Krizman DB, Nagle J, Polymeropoulos MH, Sturley SL, Ioannou YA, Higgins ME, Comly M, Cooney A, Brown A, Kaneski CR, Blanchette-Mackie EJ, Dwyer NK, Neufeld EB, Chang TY, Liscum L, Strauss JF III, Ohno K, Ziegler M, Carmi R, Sokol J, Markie D, O'Neill RO, van Diggelen OP, Elleder M, Patterson MC, Brady RO, Vanier MT, Pentchev PG, Tagle DA: Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis. Science 277: 228\u2013231, 1997","journal-title":"Science"},{"key":"276503_CR32","doi-asserted-by":"crossref","first-page":"27345","DOI":"10.1016\/S0021-9258(19)74255-0","volume":"268","author":"T Furuchi","year":"1993","unstructured":"Furuchi T, Aikawa K, Arai H, Inoue K: Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, blocks lysosomal cholesterol trafficking in macrophages. J Biol Chem 268: 27345\u201327348, 1993","journal-title":"J Biol Chem"},{"key":"276503_CR33","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1161\/01.ATV.15.9.1378","volume":"15","author":"I Maor","year":"1995","unstructured":"Maor I, Mandel H, Aviram M: Macrophage uptake of oxidized IDL inhibits lysosomal sphingomyelinase, thus causing the accumulation of unesterified cholesterol-sphingomyelin-rich particles in the lysosomes. A possible role for 7-ketocholesterol. Arterioscler Thromb Vasc Biol 15: 1378\u20131387, 1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"276503_CR34","doi-asserted-by":"crossref","first-page":"23797","DOI":"10.1016\/S0021-9258(18)35908-8","volume":"267","author":"JD Butler","year":"1992","unstructured":"Butler JD, Blanchette-Mackie J, Goldin E, O'Neill RR, Carstea G, Roff CF, Patterson MC, Patel S, Comly ME, Cooney A, Vanier MT, Brady RO, Pentchev PG: Progesterone blocks cholesterol translocation from lysosomes. J Biol Chem 267: 23797\u201323805, 1992","journal-title":"J Biol Chem"},{"key":"276503_CR35","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1126\/science.277.5323.232","volume":"277","author":"SK Loftus","year":"1997","unstructured":"Loftus SK, Morris JA, Carstea E D, Gu JZ, Cummings C, Brown A, Ellison J, Ohno K, Rosenfeld MA, Tagle DA, Pentchev PG, Pavan WJ: Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene. Science 277: 232\u2013235, 1997","journal-title":"Science"},{"key":"276503_CR36","doi-asserted-by":"crossref","first-page":"15902","DOI":"10.1016\/S0021-9258(19)49619-1","volume":"267","author":"CF Roff","year":"1992","unstructured":"Roff CF, Pastuszyn A, Strauss JF, Billheimer JT, Vanier MT, Brady RO, Scallen TJ, Pentchev PG: Deficiencies in sex-regulated expression and levels of two hepatic sterol carrier proteins in a murine model of Niemann-Pick type C disease. J Biol Chem 267: 15902\u201315908, 1992","journal-title":"J Biol Chem"},{"key":"276503_CR37","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0022-2275(20)41170-8","volume":"35","author":"WJ Johnson","year":"1994","unstructured":"Johnson WJ, Reinhart MP: Lack of requirement for sterol carrier protein-2 in the intracellular trafficking of lysosomal cholesterol. J. Lipid Res. 35: 563\u2013573, 1994","journal-title":"J. Lipid Res."},{"key":"276503_CR38","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0005-2736(79)90234-7","volume":"553","author":"Y Nakagawa","year":"1979","unstructured":"Nakagawa Y, Inoue K, Nojima S: Transfer of cholesterol between liposomal membranes. Biochim Biophys Acta 553: 307\u2013319, 1979","journal-title":"Biochim Biophys Acta"},{"key":"276503_CR39","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1042\/bj2380647","volume":"238","author":"C Bhuvaneswaran","year":"1986","unstructured":"Bhuvaneswaran C, Mitropoulos KA: Effect of liposomal phospholipid composition on cholesterol transfer between microsomal and liposomal vesicles. Biochem J 238: 647\u2013652, 1986","journal-title":"Biochem J"},{"key":"276503_CR40","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1016\/S0021-9258(18)32920-X","volume":"258","author":"BW Wattenberg","year":"1983","unstructured":"Wattenberg BW, Silbert DF: Sterol partitioning among intracellular membranes. Testing a model for cellular sterol distribution. J Biol Chem 258: 2284\u20132289, 1983","journal-title":"J Biol Chem"},{"key":"276503_CR41","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/S0022-2275(20)41642-6","volume":"32","author":"G Schmitz","year":"1991","unstructured":"Schmitz G, Muller G: Structure and function of lamellar bodies, lipidprotein complexes involved in storage and secretion of cellular lipids. J Lipid Res 32: 1539\u20131570, 1991","journal-title":"J Lipid Res"},{"key":"276503_CR42","first-page":"98","volume":"37","author":"C Bhuvaneswaran","year":"1985","unstructured":"Bhuvaneswaran C, Venkatesan S, Mitropoulos KA: Lysosomal accumulation of cholesterol and sphingomyelin: Evidence for inhibition of acid sphingomyelinase. Eur J Cell Biol 37: 98\u2013106, 1985","journal-title":"Eur J Cell Biol"},{"key":"276503_CR43","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/0006-291X(81)91965-3","volume":"100","author":"JC Maziere","year":"1981","unstructured":"Maziere JC, Wolf C, Maziere C, Mora L, Bereziat G, Polonovski J: Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol. Biochem Biophys Res Commun 100: 1299\u20131304, 1981","journal-title":"Biochem Biophys Res Commun"},{"key":"276503_CR44","first-page":"105","volume":"48","author":"C Bhuvaneswaran","year":"1999","unstructured":"Bhuvaneswaran C, Morris MD: Sphingomyelinase activity of livers from control and NCTR-BALB\/c mice. IUBMB Life 48: 105\u2013108, 1999","journal-title":"IUBMB Life"},{"key":"276503_CR45","first-page":"118","volume":"58","author":"MT Vanier","year":"1996","unstructured":"Vanier MT, Duthel S, Rodriguez-Lafrasse C, Pentchev P, Carstea ED: Genetic heterogeneity in Niemann-Pick C disease: A study using somatic cell hybridization and linkage analysis. Am J Hum Genet 58: 118\u2013125, 1996","journal-title":"Am J Hum Genet"},{"key":"276503_CR46","first-page":"373","volume":"47","author":"I Pin","year":"1990","unstructured":"Pin I, Pradines S, Pincemaille O, Frappat P, Brambilla E, Vanier MT, Bost M: Forme respiratoire mortelle de maladie de Niemann-Pick type C. Arch Fr Pediatr 47: 373\u2013375, 1990","journal-title":"Arch Fr Pediatr"},{"key":"276503_CR47","first-page":"151","volume":"49","author":"T Kunishita","year":"1979","unstructured":"Kunishita T, Taketomi T: Sphingomyelin storage in a patient with myoclonus epilepsy as a main clinical symptom. A variant in Niemann-Pick disease type C. Jpn J Exp Med 49: 151\u2013156, 1979","journal-title":"Jpn J Exp Med"},{"key":"276503_CR48","first-page":"602","volume":"43","author":"H Pilz","year":"1975","unstructured":"Pilz H, Heipertz R: Differentialdiagnose angeborener lipidosen durch lipidanalysen von k\u00f6 rperfl\u00fc ssigkeiten, biopsie-und autopsiegewebe. Fortschr Neurol Psychiat 43: 602\u2013617, 1975","journal-title":"Fortschr Neurol Psychiat"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1007180800941.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1007180800941\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1007180800941.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T12:50:19Z","timestamp":1747745419000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1007180800941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["276503"],"URL":"https:\/\/doi.org\/10.1023\/a:1007180800941","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"type":"print","value":"0300-8177"},{"type":"electronic","value":"1573-4919"}],"subject":[],"published":{"date-parts":[[2000,11]]}}}