{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T05:44:55Z","timestamp":1751867095020,"version":"3.41.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2000,11]]},"DOI":"10.1023\/a:1007632326953","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T10:54:50Z","timestamp":1040554490000},"page":"1503-1508","source":"Crossref","is-referenced-by-count":10,"title":["Effects of Ellagic Acid by Oral Administration on N-Acetylation and Metabolism of 2-Aminofluorene in Rat Brain Tissues"],"prefix":"10.1007","volume":"25","author":[{"given":"Song S.","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi F.","family":"Hung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin C.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi H.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heng C.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing G.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"290553_CR1","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/315190a0","volume":"315","author":"G. Klein","year":"1985","unstructured":"Klein, G. and Klein, E. 1985. Nature (London) 315:190\u2013195.","journal-title":"Nature (London)"},{"key":"290553_CR2","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1002\/1097-0142(19810301)47:5+<1055::AID-CNCR2820471302>3.0.CO;2-3","volume":"47","author":"E. C. Miller","year":"1981","unstructured":"Miller, E. C. and Miller, J. A. 1981. Mechanisms of chemical carcinogenesis. Cancer 47:1055\u20131064.","journal-title":"Cancer"},{"key":"290553_CR3","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1021\/ac00263a029","volume":"55","author":"D. W. Later","year":"1983","unstructured":"Later, D. W., Andros, T. C., and Lee, M. L. 1983. Isolation and identification of amino polycyclic aromatic hydrocarcinogens from coal-derived products. Anal. Chem. 55:2126\u20132132.","journal-title":"Anal. Chem."},{"key":"290553_CR4","first-page":"143","volume-title":"Environmental carcinogenesis","author":"E. Kriek","year":"1979","unstructured":"Kriek, E. 1979. Aromatic mines and related compounds as carcinogenic hazards to man. In: P. Emmelot and E. Kriek (eds), Environmental carcinogenesis. pp. 143\u2013164. Amsterdam: Elsevier\/North-Holland Biomedical Press."},{"key":"290553_CR5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev.pa.19.040179.001021","volume":"19","author":"J. L. Radomski","year":"1979","unstructured":"Radomski, J. L. 1979. The primary aromatic amines, their biological properties and structure-activity relationships. Annu. Rev. Pharmacol. Toxicol. 19:129\u2013157.","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"290553_CR6","first-page":"1535","volume":"15","author":"H. P. Morris","year":"1955","unstructured":"Morris, H. P. 1955. Hepatocarcinogenesis by 2-acetylaminofluorene and related compounds including comments on dietary and other influences. J. Natl. Cancer Inst. 15:1535\u20131545.","journal-title":"J. Natl. Cancer Inst."},{"key":"290553_CR7","first-page":"5861","volume":"47","author":"K. Rudo","year":"1987","unstructured":"Rudo, K., Meyer, W. C., Dauterman, W., and Langenbach, R. 1987. Comparison of human and rat hepatocyte metabolism and mutagenic activation of 2-acetylaminofluorene. Cancer Res. 47:5861\u20135867.","journal-title":"Cancer Res."},{"key":"290553_CR8","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0090-9556(25)08199-1","volume":"21","author":"J. G. Chung","year":"1993","unstructured":"Chung, J. G., Levy, G. N., and Weber, W. W. 1993. Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL\/6J rapid and B6.A-NatS slow acetylator congenic mice. Drug Metabol. Dispos. 21:1057\u20131063.","journal-title":"Drug Metabol. Dispos."},{"key":"290553_CR9","first-page":"504","volume":"9","author":"E. C. Miller","year":"1949","unstructured":"Miller, E. C., Miller, J. A., Sandin, R. B., and Brown, R. K. 1949. The carcinogenic activities of certain analogues of 2-acetylaminofluorene in the rat. Cancer Res. 9:504\u2013509.","journal-title":"Cancer Res."},{"key":"290553_CR10","first-page":"1317","volume":"42","author":"J. A. Miller","year":"1955","unstructured":"Miller, J. A., Sandin, R. B., Miller, E. C., and Rusch, H. P. 1955. The carcinogenicity of compounds related to 2-acetylaminofluorene. II. Variations in the bridges and the 2-substituent. Cancer Res. 42:1317\u20131321.","journal-title":"Cancer Res."},{"key":"290553_CR11","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0197-0186(97)00019-3","volume":"31","author":"J. H. Lee","year":"1997","unstructured":"Lee, J. H., Hung, C. F., Ho, C. C., Chang, S. H., Lai, Y. S., and Chung, J. G. 1997. Light-induced changes in frog pineal gland N-acetyltransferase activity. Neurochem. Int. 31:533\u2013540.","journal-title":"Neurochem. Int."},{"key":"290553_CR12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0278-6915(92)90006-7","volume":"30","author":"A. D. Aryton","year":"1992","unstructured":"Aryton, A. D., Lewis, D. F. V., Walker, R., and Ionnides, C. 1992. Antimutagenicity of ellagic acid towards the food mutagen IQ: investigation into possible mechanisms of action. Fd. Chem. Toxicol. 30:289\u2013295.","journal-title":"Fd. Chem. Toxicol."},{"issue":"Suppl.","key":"290553_CR13","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/jcb.240590822","volume":"22","author":"G. D. Stoner","year":"1995","unstructured":"Stoner, G. D. and Mukhtar, H. 1995. Polyphenols as cancer chemopreventive agents. J. Cell Biochem. 22(Suppl.):169\u2013180.","journal-title":"J. Cell Biochem."},{"key":"290553_CR14","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1111\/j.1349-7006.1988.tb01559.x","volume":"79","author":"T. Tanaka","year":"1988","unstructured":"Tanaka, T., Iwata, H., Niwa, K., Mori, Y., and Mori, H. 1988. Inhibitory effect of ellagic acid on N-2-fluorenylacetamide-induced liver carcinogenesis in male AVI\/N rats. Jpn. J. Cancer Res. (Gann.). 79:1297\u20131303.","journal-title":"Jpn. J. Cancer Res. (Gann.)."},{"key":"290553_CR15","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/carcin\/6.10.1409","volume":"6","author":"M. Das","year":"1985","unstructured":"Das, M., Bickers, D. R., and Mukhtar, H. 1985. Effects of ellagic acid on hepatic and pulmonary xenobiotic metabolism in mice: studies of the mechanism of its anticarcinogenic action. Carcinogenesis 6:1409\u20131413.","journal-title":"Carcinogenesis"},{"key":"290553_CR16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/carcin\/11.1.55","volume":"11","author":"S. Mandal","year":"1990","unstructured":"Mandal, S. and Stoner, G. D. 1990. Inhibition of of N-nitro-sobenzylmethylamine-induced esophageal tumorigenesis in rats by ellagic acid. Carcinogenesis 11:55\u201361.","journal-title":"Carcinogenesis"},{"key":"290553_CR17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0304-3835(95)03833-I","volume":"94","author":"K. Akagi","year":"1995","unstructured":"Akagi, K., Hirose, M., Hosgiya, T., Mizoguchi, Y., Ito, N., and Shirai, T. 1995. Modulating effects of ellagic acid, vanillin and quercetin in rat medium term multi-organ carcinogenesis model. Cancer Letts. 94:113\u2013121.","journal-title":"Cancer Letts."},{"key":"290553_CR18","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1093\/carcin\/17.4.821","volume":"17","author":"D. Ahn","year":"1996","unstructured":"Ahn, D., Puto, D., Kresty, L., Stoner, G. D., Fromm, D., and Hollenberg, F. 1996. The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochromes P450 and phase II enzyme. Carcinogenesis 17:821\u2013828","journal-title":"Carcinogenesis"},{"key":"290553_CR19","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1080\/02772249909358803","volume":"71","author":"C. C. Ho","year":"1999","unstructured":"Ho, C. C., Tsai, H. Y., Lai, Y. S., and Chung, J. G. 1999. Effects of the ellagic acid on the N-acetyltransferase activity and acetylation of 2-aminofluorene in the rat. Toxicol. Environ. Chem. 71:319\u2013329.","journal-title":"Toxicol. Environ. Chem."},{"key":"290553_CR20","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"M. M. Bradford","year":"1976","unstructured":"Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248\u2013254.","journal-title":"Anal. Biochem."},{"key":"290553_CR21","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1023\/A:1015964306318","volume":"6","author":"C. K. Svensson","year":"1989","unstructured":"Svensson, C. K. and Knowlton, P. W. 1989. Effect of the immunomodulator tilorone on the in vivo acetylation of procainamide in the rat. Pharmaceutical Res. 6:477\u2013450.","journal-title":"Pharmaceutical Res."},{"key":"290553_CR22","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0006-291X(92)91703-S","volume":"185","author":"R. F. Minchin","year":"1992","unstructured":"Minchin, R. F., Reeves, P. T., Teitel, C. H., McManus, M. E., Mojarrabi, T., Ilett, K. F., and Kadlubar, F. F. 1992. N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferase expressed in COS-1 cells. Biochem. Biophys. Res. Commun. 185: 839\u2013844.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"290553_CR23","first-page":"3961","volume":"52","author":"D. M. Grant","year":"1992","unstructured":"Grant, D. M., Josephy, P. D., and Lord, H. L. 1992. Salmonella typhimurium strains expressing human arylamine N-acetyltransferase: metabolism and mutagenic activation of aromatic amines. Cancer Res. 52:3961\u20133964.","journal-title":"Cancer Res."},{"key":"290553_CR24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0031-6997(25)06816-4","volume":"37","author":"W. W. Weber","year":"1985","unstructured":"Weber, W. W. and Hein, D. W. 1985. N-acetylation pharmacogenetics. Pharmacol. Review. 37:25\u201379.","journal-title":"Pharmacol. Review."},{"key":"290553_CR25","volume-title":"The acetylator genes and drug response","author":"W. W. Weber","year":"1987","unstructured":"Weber, W. W. 1987. The acetylator genes and drug response, Oxford University Press. New York."},{"key":"290553_CR26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0165-1218(91)90113-Z","volume":"259","author":"P. Einisto","year":"1991","unstructured":"Einisto, P., Watanabe, M., Ishidate, M., and Nohmi, T. 1991. Mutagenicity of 30 chemicals in S. Typhimurium possessing different nitroreductase or O-acetyltransferase activities. Mutation Res. 259:95\u2013102.","journal-title":"Mutation Res."},{"key":"290553_CR27","first-page":"99A","volume":"16","author":"D. H. Barch","year":"1992","unstructured":"Barch, D. H. and Rundhaugen, L. M. 1992. Hepatology 16:99A.","journal-title":"Hepatology"},{"key":"290553_CR28","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1006\/bbrc.1994.1870","volume":"201","author":"D. A. Barch","year":"1994","unstructured":"Barch, D. A., Rundhaugen, L. M., Thomas, P. E., and Kardos, P. 1994. Dietary ellagic acid inhibits the enzymatic activity of CYP1A1 without altering hepatic concentrations of CYP1A1 or CYP1A1 mRNA. Biochem. Biophys. Res. Commun. 201: 1477\u20131482.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"290553_CR29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0010-468X(83)90082-X","volume":"16","author":"M. L. Rocci Jr.","year":"1983","unstructured":"Rocci, M. L., Jr. and Jusko, W. J. 1983. LAGRAN program for area and moments in pharmacokinetic analysis. Comp. Prog. Biomed. 16:203\u2013216.","journal-title":"Comp. Prog. Biomed."},{"key":"290553_CR30","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0006-2952(77)90134-4","volume":"26","author":"Z. Zidek","year":"1981","unstructured":"Zidek, Z., Friebova, M., Janku, I., and Elis, J. 1981. Influence of sex and Freund's adjuvant on liver N-acetyltransferase activity and elimination of sulphadimidine in urine of rats. Biochem. Pharmacol. 26:69\u201370.","journal-title":"Biochem. Pharmacol."},{"key":"290553_CR31","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0090-9556(25)06144-6","volume":"9","author":"P. DuSouich","year":"1981","unstructured":"DuSouich, P. and Courteau, H. 1981. Induction of acetylation capacity with complete Freund's adjuvant and hydrocortisone in the rabbit. Drug Metab. Dispos. 9:279\u2013283.","journal-title":"Drug Metab. Dispos."},{"key":"290553_CR32","first-page":"467","volume":"20","author":"J. G. Chung","year":"2000","unstructured":"Chung, J. G., Chang, H. L., Yeh, C. C., Lu, H. F., Chang, C. C., and Tsai, H. D. 2000. Effects of the immunodulator tilorone on the acetylation of 2-aminofluorene and DNA-2-aminofluorene adducts in the rats. Anticancer Res. 20:467\u2013473.","journal-title":"Anticancer Res."},{"key":"290553_CR33","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0090-9556(25)06884-9","volume":"16","author":"P. T. Reeves","year":"1987","unstructured":"Reeves, P. T., Minchin, R. F., and Ilett, K. F. 1987. Induction of sulfamethazine acetylation by hydrocortisone in the rabbit. Drug Metab. Dispos. 16:110\u2013115.","journal-title":"Drug Metab. Dispos."}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1007632326953.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1007632326953\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1007632326953.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T05:27:16Z","timestamp":1751866036000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1007632326953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["290553"],"URL":"https:\/\/doi.org\/10.1023\/a:1007632326953","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"type":"print","value":"0364-3190"},{"type":"electronic","value":"1573-6903"}],"subject":[],"published":{"date-parts":[[2000,11]]}}}