{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:56:39Z","timestamp":1790542599338,"version":"4.1.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1999,6,1]],"date-time":"1999-06-01T00:00:00Z","timestamp":928195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1999,6,1]],"date-time":"1999-06-01T00:00:00Z","timestamp":928195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[1999,6]]},"DOI":"10.1023\/a:1008899111209","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T11:51:56Z","timestamp":1040557916000},"page":"227-231","source":"Crossref","is-referenced-by-count":26,"title":["The relation of p53 gene mutations to gastric cancer subsite and phenotype"],"prefix":"10.1007","volume":"10","author":[{"given":"D.","family":"Tolbert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Fenoglio-Preiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Noffsinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. De","family":"Voe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Benedetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.N.","family":"Stemmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"202667_CR1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3322\/canjclin.48.1.6","volume":"48","author":"SH Landis","year":"1998","unstructured":"Landis SH, Murray T, Bolden S, Wingo PA (1998) Cancer Statistics, 1998. CA Cancer J Clin\n48: 6-29.","journal-title":"CA Cancer J Clin"},{"key":"202667_CR2","unstructured":"Parkin DM, Muir C, Whelan SK, Ga OYT, Ferlay J, Powell J, eds. (1992) Cancer Incidence in Five Continents. Volume 6, Lyon: IARC Publications No. 120, 1992."},{"key":"202667_CR3","first-page":"3544","volume":"48","author":"P Correa","year":"1988","unstructured":"Correa P (1988) A human model for gastric carcinogenesis. Cancer Res\n48: 3544-3560.","journal-title":"Cancer Res"},{"key":"202667_CR4","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1056\/NEJM199110173251604","volume":"325","author":"A Nomura","year":"1991","unstructured":"Nomura A, Stemmermann GN, Chyou P-H, Kato I, Perez-Perez GI, Blaser M (1991) Helicobacter pylori and its relation to stomach cancer in a population of Japanese Americans in Hawaii. N Eng J Med\n325: 1132-1136.","journal-title":"N Eng J Med"},{"key":"202667_CR5","first-page":"707","volume-title":"Cancer Epidemiology and Prevention","author":"A Nomura","year":"1996","unstructured":"Nomura A (1996) Stomach cancer. In: Schottenfeld D, Fraumeni JF, eds. Cancer Epidemiology and Prevention, 2nd edn. Oxford: Oxford University Press, pp. 707-724.","edition":"2nd edn."},{"key":"202667_CR6","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/0016-5085(95)90398-4","volume":"109","author":"LE Hansson","year":"1995","unstructured":"Hansson LE, Engstrand L, Nyren O, Lindgren A (1995) Prevalence of Helicobacter pylori infection in subtypes of gastric cancer. Gastroenterology\n109: 885-888.","journal-title":"Gastroenterology"},{"key":"202667_CR7","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ijc.2910080118","volume":"8","author":"N Munoz","year":"1971","unstructured":"Munoz N, Asvall J (1971) Time trends of diffuse and intestinal types of cancer in Norway. Int J Cancer\n8: 144-157.","journal-title":"Int J Cancer"},{"key":"202667_CR8","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/1097-0142(19930715)72:2<330::AID-CNCR2820720205>3.0.CO;2-L","volume":"72","author":"T Zheng","year":"1993","unstructured":"Zheng T, Mayne ST, Holford TR, Boyle P, Liu W, Chen Y, Mador M, Flannery J (1993) The time trend and age-period-cohort effects on incidence of adencarcinoma of the stomach in Connecticut from 2955-89. Cancer\n72: 330-340.","journal-title":"Cancer"},{"key":"202667_CR9","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/1097-0142(19870901)60:5<1094::AID-CNCR2820600529>3.0.CO;2-4","volume":"60","author":"WC MacDonald","year":"1987","unstructured":"MacDonald WC, MacDonald JB (1987) Adenocarcinoma of the esophagus and\/or cardia of the stomach. Cancer\n60: 1094-1098.","journal-title":"Cancer"},{"key":"202667_CR10","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/bjc.1992.149","volume":"65","author":"R Seruca","year":"1992","unstructured":"Seruca R, David L, Holm R, Nesland JM, Fangan BM, Castedo S, Sobrinho-Simoes M, Borresen AL (1992) p53 mutations in gastric cancer. Br J Cancer\n65: 708-710.","journal-title":"Br J Cancer"},{"key":"202667_CR11","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/jnci\/83.13.938","volume":"83","author":"JH Kim","year":"1991","unstructured":"Kim JH, Takahashi T, Chiba I, Park JG, Birrer MJ, Roh JK, Lee HD, Kim JP, Minna JD, Gazdar AF (1991) Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines. J Natl Cancer Inst\n83: 938-943.","journal-title":"J Natl Cancer Inst"},{"key":"202667_CR12","first-page":"5800","volume":"51","author":"Y Yamada","year":"1991","unstructured":"Yamada Y, Yoshida T, Hayashi K, Sekiya T, Yokota J, Hirohashi S, Nakatani K, Nakano H, Sugimura T, Terada M (1991) p53 gene mutations in gastric cancer and in gastric cancer cell lines derived from metastases. Cancer Res\n51: 5800-5805.","journal-title":"Cancer Res"},{"key":"202667_CR13","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1002\/(SICI)1097-0142(19960415)77:8<1620::AID-CNCR30>3.0.CO;2-#","volume":"77","author":"S Semba","year":"1996","unstructured":"Semba S, Yokozaki H, Yamamoto S, Yasui W, Tahara E (1996) Microsatellite instability in precancerous lesions and carcinoma of the stomach. Cancer\n77: 1620-1627.","journal-title":"Cancer"},{"key":"202667_CR14","first-page":"2614","volume":"53","author":"B Renault","year":"1993","unstructured":"Renault B, van den Broek M, Fodde R, Wijten J, Pellegat NS, Amadori D, Kahn PM, Ranzani GN (1993) Base transitions are the most frequent genetic changes at p53 in gastric cancer. Cancer Res\n53: 2614-2617.","journal-title":"Cancer Res"},{"key":"202667_CR15","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/ijc.2910540509","volume":"54","author":"S Uchino","year":"1993","unstructured":"Uchino S, Noguchi M, Ochiai A, Saito T, Kobayahi M, Hirohashi S (1993) p53 mutation in gastric cancer: Model for carcinogenesis is common to gastric and colorectal cancer Int J cancer\n54: 759-764.","journal-title":"Int J cancer"},{"key":"202667_CR16","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/0016-5085(92)90022-Q","volume":"103","author":"F Imazeki","year":"1992","unstructured":"Imazeki F, Omata M, Nose H, Ohto M, Isono K (1992) p53 mutations in gastric and esophageal cancers. Gastroenterology\n103: 892-896.","journal-title":"Gastroenterology"},{"key":"202667_CR17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF01209657","volume":"119","author":"H Yokozaki","year":"1992","unstructured":"Yokozaki H, Kuniyasu H, Kitadai Y, Nishimura K, Todo H, Ayhan A, Yasui W, Ito H, Tahara E (1992) p53 point mutations in primary gastric carcinomas. J Cancer Res Clin Oncol\n119: 67-70.","journal-title":"J Cancer Res Clin Oncol"},{"key":"202667_CR18","first-page":"859","volume":"59","author":"K Motojima","year":"1992","unstructured":"Motojima K, Furui J, Kohara N, Ito T, Kanematsu T (1992) Expression of p53 protein in gastric carcinomas is not independently prognostic. Int J Cancer\n59: 859-862.","journal-title":"Int J Cancer"},{"key":"202667_CR19","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/ijc.2910500604","volume":"50","author":"HM Martin","year":"1992","unstructured":"Martin HM, Filipe MI, Morris RW, Lane DP, Silvestre F (1992) p53 expression and prognosis in gastric carcinoma. Int J Cancer\n50: 859-862.","journal-title":"Int J Cancer"},{"key":"202667_CR20","first-page":"3056","volume":"51","author":"G Tamura","year":"1991","unstructured":"Tamura G, Kihana T, Nomura K, Terada M, Sugimura T (1991) Detection of p53 mutations in primary gastric cancer by cell sorting and polymerase chain reaction single strand polymorphism analysis. Cancer Res\n51: 3056-3058.","journal-title":"Cancer Res"},{"key":"202667_CR21","first-page":"54","volume":"12","author":"DM Tolbert","year":"1999","unstructured":"Tolbert DM, Noffsinger A, Miller MA, De Voe G, Stemmermann GN, MacDonald JS, Fenoglio-Preiser CM (1999) p53 immunoreactivity and single strand polymorphism analysis often fail to predict p53 mutational status. Modern Pathology\n12: 54-60.","journal-title":"Modern Pathology"},{"key":"202667_CR22","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","volume":"64","author":"T Lauren","year":"1965","unstructured":"Lauren T (1965) The two histologic main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. Acta Pathol Microbiol Scand\n64: 31-49.","journal-title":"Acta Pathol Microbiol Scand"},{"key":"202667_CR23","unstructured":"AJCC Cancer Staging Manual, 5th edn (1998) Philadelphia: Lippincott-Ravan, pp. 71-75."},{"key":"202667_CR24","first-page":"761","volume":"5","author":"Z-F Zhang","year":"1996","unstructured":"Zhang Z-F, Kurtz RC, Karpeh M Jr, Yu G-P, Gargon N, Fein JS, Georgopoulos SK, Harlap S (1996) Adenocarcinoma of the esophagus and gastric cardia: Medical conditions, tobacco, alcohol and socioeconomic factors. Cancer Epidemiol Biomarkers Prev\n5: 761-768.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"202667_CR25","first-page":"3406","volume":"55","author":"CM Gleeson","year":"1995","unstructured":"Gleeson CM, Sloan JM, McGuigan JA, Ritchie AJ, Russell SEH (1995) Base transitions at CpG dinucleotides in the p53 gene are common in esophageal adenocarcinoma. Cancer Res\n55: 3406-3411.","journal-title":"Cancer Res"},{"key":"202667_CR26","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/0016-5085(94)90225-9","volume":"107","author":"R Hamelin","year":"1994","unstructured":"Hamelin R, Flejou JF, Muzeau F, Potet F, Laurent-Puig P, Fekete F, Thomas G (1994) TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barret's esophagus. Gastroenterology\n107: 1012-1017.","journal-title":"Gastroenterology"},{"key":"202667_CR27","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/0016-5085(94)90415-4","volume":"106","author":"K Neshat","year":"1994","unstructured":"Neshat K, Sanchez CA, Galipeau PC, Blount PL, Levine DS, Joslyn G, Reid BJ (1994) p53 mutations in Barrett's adenocarcinoma and high grade dysplasia. Gastroenterology\n106: 1589-1595.","journal-title":"Gastroenterology"},{"key":"202667_CR28","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0022-5223(96)70441-5","volume":"111","author":"PM Schneider","year":"1996","unstructured":"Schneider PM, Casson AG, Levin B, Garewal HS, Hoelscher AH, Becker K, Dittler HJ, Cleary KR, Troster M, Siewert JR, Roth JA (1996) Mutations of p53 in Barrett's esophagus and Barrett's cancer: prospective study of ninety-eight cases. J Thor Cardiac Surg\n111: 323-331.","journal-title":"J Thor Cardiac Surg"},{"key":"202667_CR29","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1097\/00000478-199600001-00003","volume":"20","author":"E Solcia","year":"1996","unstructured":"Solcia E, Fiocca R, Luinetti O, Vilani L, Padovan L, Calistri D, Ranzani GN, Chiavalli A, Capella C (1996) Intestinal and diffuse gastric cancers arise on a different background of Helicobacter pylori gastritis through different gene involvement. Am J Surg Path\n20: S8-S22.","journal-title":"Am J Surg Path"},{"key":"202667_CR30","first-page":"97","volume":"7","author":"DC Farrow","year":"1998","unstructured":"Farrow DC, Vaughn TL, Hansten PD, Stanford JL, Risch HA, Gammon MD, Chow WH, Dubrow R, Ahsan H, Mayne ST, Schoenberg JB, West AB, Rotterdam H, Fraumeni JF, Bolt WJ (1998) Use of aspirin and other nonsteroidal anti-inflammatory drugs and the risk of esophageal and gastric cancer. Cancer Epidemiol Biomarkers Prev\n7: 97-102.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"202667_CR31","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3109\/00365529709007676","volume":"32","author":"C Martin-de-Argila","year":"1997","unstructured":"Martin-de-Argila C, Boixida D, Redondo I, Alverez I, Gisbert JP, Garcia Plaza A, Canton R (1997) Relation between histologic subtypes and location of gastric cancer and Helicobacter pylori. Scand J Gastroenterol\n32: 303-307.","journal-title":"Scand J Gastroenterol"},{"key":"202667_CR32","first-page":"588","volume":"58","author":"W-H Chow","year":"1998","unstructured":"Chow W-H, Blaser M, Blot W, Gammon MD, Vaughn TL, Risch HA, Perez-Perez GL, Schoenberg JB, Stanford JL, Rotterdam H, West AB, Fraumeni JF (1998) An inverse relation between cagA\n+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma. Cancer Res\n58: 588-590.","journal-title":"Cancer Res"},{"key":"202667_CR33","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/S0016-5085(97)70024-6","volume":"112","author":"J Labenz","year":"1997","unstructured":"Labenz J, Blum AL, Bayerdorffer E, Meining A, Stolte M, Borsch G (1997) Curing Helicobacter pylori infection in patients with duodenal ulcer may provoke reflux esophagitis. Gastroenterology\n112: 1442-1447.","journal-title":"Gastroenterology"},{"key":"202667_CR34","first-page":"2019","volume":"113","author":"B Jaup","year":"1997","unstructured":"Jaup B (1997) Gastroesophageal reflux after cure of H. pylori infection. Gastroenterology\n113: 2019.","journal-title":"Gastroenterology"}],"container-title":["Cancer Causes &amp; Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1008899111209.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1008899111209\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1008899111209.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T14:37:16Z","timestamp":1750948636000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1008899111209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,6]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,6]]}},"alternative-id":["202667"],"URL":"https:\/\/doi.org\/10.1023\/a:1008899111209","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,6]]}}}