{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:41:58Z","timestamp":1777441318301,"version":"3.51.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1999,8,1]],"date-time":"1999-08-01T00:00:00Z","timestamp":933465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1999,8,1]],"date-time":"1999-08-01T00:00:00Z","timestamp":933465600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[1999,8]]},"DOI":"10.1023\/a:1008989103809","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T17:46:35Z","timestamp":1040579195000},"page":"417-421","source":"Crossref","is-referenced-by-count":30,"title":["A case\u2013control study on family history of liver cancer as a risk factor for hepatocellular carcinoma in North Italy"],"prefix":"10.1007","volume":"10","author":[{"given":"Francesco","family":"Donato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"Gelatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Chiesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Albertini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Bucella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Boffetta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Tagger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Lisa","family":"Ribero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Portera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Fasola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Nardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"233918_CR1","series-title":"IARC Monographs","volume-title":"Alcohol drinking","author":"International Agency for Research on Cancer","year":"1988","unstructured":"International Agency for Research on Cancer (IARC) (1988) Alcohol drinking. Lyon: International Agency for Research on Cancer, IARC Monographs, Lyon, 44."},{"key":"233918_CR2","unstructured":"International Agency for Research on Cancer (IARC) (1994) Hepatitis Viruses. IARC monographs on the evaluation of carcinogenic risks to humans, Lyon, 59."},{"key":"233918_CR3","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1093\/jnci\/86.21.1600","volume":"86","author":"DE Goldgar","year":"1994","unstructured":"Goldgar DE, Easton DF, Cannon-Albright LA, Skolnick MH (1994) Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands. J Natl Cancer Inst\n86: 1600-1608.","journal-title":"J Natl Cancer Inst"},{"key":"233918_CR4","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/(SICI)1097-0215(19981005)78:2<172::AID-IJC9>3.0.CO;2-W","volume":"78","author":"K Hemminki","year":"1998","unstructured":"Hemminki K, Vaittinen P, Kyyronen P (1998) Age-specific familial risks in common cancer of the offspring. Int J Cancer, 78: 172-175.","journal-title":"Int J Cancer"},{"key":"233918_CR5","first-page":"128","volume":"59","author":"C-J Chen","year":"1996","unstructured":"Chen C-J, Yu MW, Liaw YF, et al. (1996) Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma. Am J Hum Genet\n59: 128-134.","journal-title":"Am J Hum Genet"},{"key":"233918_CR6","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/00008571-199612000-00003","volume":"6","author":"JA Agundez","year":"1996","unstructured":"Agundez JA, Olivera M, Ladero JM, et al. (1996) Increased risk for hepatocellular carcinoma in NAT2-slow acetylators and CYP2D6-rapid metabolizers. Pharmacogenetics\n6: 501-512.","journal-title":"Pharmacogenetics"},{"key":"233918_CR7","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1073\/pnas.92.6.2384","volume":"92","author":"KA McGlynn","year":"1995","unstructured":"McGlynn KA, Rosvold EA, Lutsbader ED, et al. (1995) Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc Natl Acad Sci USA\n92: 2384-2387.","journal-title":"Proc Natl Acad Sci USA"},{"key":"233918_CR8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/gepi.1370080206","volume":"8","author":"SR Alberts","year":"1991","unstructured":"Alberts SR, Lanier AP, McMahon BJ, et al. (1991) Clustering of hepatocellular carcinoma in Alaska Native families. Genet Epidemiol\n8: 127-139.","journal-title":"Genet Epidemiol"},{"key":"233918_CR9","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ijc.2910300109","volume":"30","author":"HW Hann","year":"1982","unstructured":"Hann HW, Kim CY, London WT, Whitford P, Blumberg BS (1982) Hepatitis B virus and primary hepatocellular carcinoma: family studies in Korea. Int J Cancer\n30: 47-51.","journal-title":"Int J Cancer"},{"key":"233918_CR10","first-page":"207","volume":"20","author":"N N'Dri","year":"1991","unstructured":"N'Dri N, Hadengue A, Benhamou JP (1991) Familial hepatocellular carcinoma in B or non-A non-B cirrhosis. Report of 4 families. Presse Med\n20: 207-209.","journal-title":"Presse Med"},{"key":"233918_CR11","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/ijc.2910510402","volume":"51","author":"K Tanaka","year":"1992","unstructured":"Tanaka K, Hirohata T, Takeshita S, et al. (1992) Hepatitis B virus, cigarette smoking and alcohol consumption in the development of hepatocellular carcinoma: a case-control study in Fukuoka, Japan. Int J Cancer\n51: 509-514.","journal-title":"Int J Cancer"},{"key":"233918_CR12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/ijc.2910450205","volume":"45","author":"H Tsukuma","year":"1990","unstructured":"Tsukuma H, Hiyama T, Oshima A, et al. (1990) A case-control study of hepatocellular carcinoma in Osaka, Japan. Int J Cancer\n45: 231-236.","journal-title":"Int J Cancer"},{"key":"233918_CR13","first-page":"209","volume":"3","author":"E Fernandez","year":"1994","unstructured":"Fernandez E, La Vecchia C, D'Avanzo B, Negri E, Franceschi S (1994) Family history and the risk of liver, gallbladder, and pancreatic cancer. Cancer Epidemiol Biomarker Prev\n3: 209-212.","journal-title":"Cancer Epidemiol Biomarker Prev"},{"key":"233918_CR14","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1002\/hep.510290330","volume":"29","author":"M-W Yu","year":"1999","unstructured":"Yu M-W, Yang S-Y, Chiu Y-H, Chiang Y-C, Liaw Y-F, Chen C-J (1999) A p53 genetic polymorphism as a modulator of hepatocellular carcinoma in relation to chronic liver disease, familial tendency, and cigarette smoking in hepatitis B carriers. Hepatology\n29: 697-702.","journal-title":"Hepatology"},{"key":"233918_CR15","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/hep.510240108","volume":"24","author":"C-J Chen","year":"1996","unstructured":"Chen C-J, Wang L-Y, Lu S-N, et al. (1996) Elevated aflatoxin exposure and increased risk of hepatocellular carcinoma. Hepatology\n24: 38-42.","journal-title":"Hepatology"},{"key":"233918_CR16","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1159\/000150426","volume":"38","author":"WT London","year":"1995","unstructured":"London WT, Evans AA, McGlynn K, et al. (1995) Viral, host and environmental risk factors for hepatocellular carcinoma: a prospective study in Haimenn City, China. Intervirology\n38: 155-161.","journal-title":"Intervirology"},{"key":"233918_CR17","first-page":"559","volume-title":"Cancer Epidemiology and Prevention","author":"LC Strong","year":"1996","unstructured":"Strong LC, Amos CI (1996) Inherited susceptibility. In: Schottenfeld D, Fraumeni JF, Jr (eds.) Cancer Epidemiology and Prevention. New York: Oxford University Press, pp. 559-586."},{"key":"233918_CR18","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/hep.510260308","volume":"26","author":"F Donato","year":"1997","unstructured":"Donato F, Tagger A, Chiesa R, et al. (1997) Hepatitis B and C virus infection, alcohol drinking and hepatocellular carcinoma: a case-control study in Italy. Hepatology\n26: 579-584.","journal-title":"Hepatology"},{"key":"233918_CR19","first-page":"127","volume":"6","author":"G Corrao","year":"1994","unstructured":"Corrao G, Busellu G, Valenti M, Torchio P, Galatola G, Di Orio F (1994) Reproducibility of measuring lifetime alcohol consumption by a simple interview-administered questionnaire. Alcologia\n6: 127-135.","journal-title":"Alcologia"},{"key":"233918_CR20","volume-title":"Applied Logistic Regression","author":"DW Hosmer","year":"1989","unstructured":"Hosmer DW, Lemeshow S (1989) Applied Logistic Regression. New York: John Wiley & Sons."},{"key":"233918_CR21","volume-title":"Modern Epidemiology","author":"KJ Rothman","year":"1986","unstructured":"Rothman KJ (1986) Modern Epidemiology. Boston: Little, Brown & Co."},{"key":"233918_CR22","volume-title":"BMDP Statistical Software Manual","author":"WJ Dixon","year":"1990","unstructured":"Dixon WJ, Brown MB, Engelman L, Iennrich NI (1990) BMDP Statistical Software Manual. Los Angeles: University of California Press."},{"key":"233918_CR23","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1001\/jama.1995.03530180053030","volume":"274","author":"K Nakashima","year":"1995","unstructured":"Nakashima K, Ikematsu H, Hayashi J, Kishihara Y, Mitsutake A, Kashiwagi S (1995) Intrafamilial transmission of hepatitis C virus among the population of an endemic area of Japan. JAMA\n274: 1459-1461.","journal-title":"JAMA"},{"key":"233918_CR24","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1017\/S0033291700013192","volume":"20","author":"KR Merikangas","year":"1990","unstructured":"Merikangas KR (1990) The genetic epidemiology of alcoholism. Psychol Med\n20: 11-22.","journal-title":"Psychol Med"},{"key":"233918_CR25","first-page":"166","volume":"19","author":"AC Heath","year":"1995","unstructured":"Heath AC (1995) Genetic influences on alcoholism risk. Alcohol Health Res World\n19: 166-171.","journal-title":"Alcohol Health Res World"},{"key":"233918_CR26","first-page":"88","volume":"49","author":"F-M Shen","year":"1991","unstructured":"Shen F-M, Lee MK, Gong H-M, Cai X-Q, King M-C (1991) Complex segregation analysis of primary hepatocellular carcinoma in Chinese families: interaction of inherited susceptibility and hepatitis B viral infection. Am J Hum Genet\n49: 88-93.","journal-title":"Am J Hum Genet"},{"key":"233918_CR27","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0168-8278(96)80068-7","volume":"25","author":"JD Collier","year":"1996","unstructured":"Collier JD, Bassendine MF, Burt AD, Major GN (1996) Characterisation of the DNA repair enzyme for O6-methylguanine in cirrhosis. J Hepatol\n25: 158-165.","journal-title":"J Hepatol"},{"key":"233918_CR28","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/oxfordjournals.aje.a009259","volume":"146","author":"RA Kerber","year":"1997","unstructured":"Kerber RA, Slattery ML (1997) Comparison of self-reported and database-linked family history of cancer data in a case-control study. Am J Epidemiol\n146: 244-248.","journal-title":"Am J Epidemiol"},{"key":"233918_CR29","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/ije\/19.4.1107","volume":"19","author":"CD Drews","year":"1990","unstructured":"Drews CD, Greenland S (1990) The impact of differential recall on the results of case-control studies. Int J Epidemiol\n19: 1107-1112.","journal-title":"Int J Epidemiol"}],"container-title":["Cancer Causes &amp; Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1008989103809.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1008989103809\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1008989103809.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T18:14:38Z","timestamp":1750961678000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1008989103809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,8]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,8]]}},"alternative-id":["233918"],"URL":"https:\/\/doi.org\/10.1023\/a:1008989103809","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,8]]}}}