{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T06:54:05Z","timestamp":1780556045163,"version":"3.54.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biometals"],"published-print":{"date-parts":[[1998,3]]},"DOI":"10.1023\/a:1009266705308","type":"journal-article","created":{"date-parts":[[2003,3,28]],"date-time":"2003-03-28T22:25:21Z","timestamp":1048890321000},"page":"1-12","source":"Crossref","is-referenced-by-count":25,"title":["Selective growth promotion and growth inhibition of Gram-negative and Gram-positive bacteria by synthetic siderophore-\u03b2-lactam conjugates"],"prefix":"10.1007","volume":"11","author":[{"given":"Ute","family":"M\u00f6llmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric K.","family":"Dolence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia A.","family":"Dolence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuka","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin J.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Reissbrodt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"170413_CR1","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1021\/jm00107a013","volume":"34","author":"EK Dolence","year":"1991","unstructured":"Dolence EK, Lon CE, Miller MJ. 1991a Synthesis and siderophore activity of albomycin-like peptides derived from N\n5-acetyl-N\n5-hydroxy-L-ornithine. J Med Chem\n34, 956\u2013968.","journal-title":"J Med Chem"},{"key":"170413_CR2","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1021\/jm00107a014","volume":"34","author":"EK Dolence","year":"1991","unstructured":"Dolence EK, Minnick AA, Lin CE, Miller MJ, Payne SM. 1991b Synthesis, siderophore and antibacterial activity of N\n5-acetyl-N\n5-hydroxy-L-ornithine derived siderophore-\u03b2-lactam conjugates: iron transport mediated drug delivery. J Med Chem\n34, 968\u2013978.","journal-title":"J Med Chem"},{"key":"170413_CR3","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1021\/bi00831a002","volume":"8","author":"JL Corbin","year":"1969","unstructured":"Corbin JL, Bulen W. 1969 The isolation and identification of 2,3 dihydroxybenzoic acid and 2-N,6-N-(2,3-dihydroxybenzoyl)-L-lysine formed by iron-deficient Azobacter vinelandii. Biochemistry\n8, 757\u2013764.","journal-title":"Biochemistry"},{"key":"170413_CR4","doi-asserted-by":"crossref","first-page":"7652","DOI":"10.1021\/jo00079a007","volume":"58","author":"A Ghosh","year":"1993","unstructured":"Ghosh A, Miller MJ. 1993 Synthesis of novel citrate-based siderophores and siderophore-\u03b2-lactam conjugates. Iron transport-mediated drug delivery systems. J Org Chem\n58 7652\u20137659.","journal-title":"J Org Chem"},{"key":"170413_CR5","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1021\/jo00084a018","volume":"59","author":"M Ghosh","year":"1994","unstructured":"Ghosh M, Miller MJ. 1994 Iron transport-mediated drug delivery: synthesis and biological evaluation of cyanuric acid-based siderophore analogs and \u03b2-lactam conjugates. J Org Chem\n59, 1020\u20131026.","journal-title":"J Org Chem"},{"key":"170413_CR6","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/S1074-5521(96)90167-2","volume":"3","author":"A Ghosh","year":"1996","unstructured":"Ghosh A, Ghosh M, Niu C, Malouin F, M\u00f6llmann U, Miller MJ. 1996 Iron transport-mediated drug delivery. Synthesis and biological evaluation of spermidine-based mixed catechol and hydroxamate-containing siderophore \u03b2-lactam conjugates. Chemistry and Biology\n3, 1011\u20131019.","journal-title":"Chemistry and Biology"},{"key":"170413_CR7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1021\/bc00010a013","volume":"2","author":"JA McKee","year":"1991","unstructured":"McKee JA, Sharma SK, Miller MJ. 1991 Iron transport mediated drug delivery systems: synthesis and antibacterial activity of spermidine\u2013 and lysine-based siderophone \u03b2-lactam conjugate. Bioconjugates Chem\n2, 281\u2013291","journal-title":"Bioconjugates Chem"},{"key":"170413_CR8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1021\/ar00029a003","volume":"26","author":"MJ Miller","year":"1993","unstructured":"Miller MJ, Malouin F. 1993 Microbial iron chelators as drug delivery agents: the rational design and synthesis of siderophore-drug conjugates. Accts Chem Res\n26, 241\u2013249.","journal-title":"Accts Chem Res"},{"key":"170413_CR9","first-page":"275","volume-title":"The Development of Iron Chelators for Clinical Use","author":"MJ Miller","year":"1994","unstructured":"Miller MJ, Malouin R. 1994 Siderophore-mediated drug delivery: the design, synthesis and study of siderophore-antibiotic and antifungal conjugates. In: Bergeron R, Brittenham GM, eds. The Development of Iron Chelators for Clinical Use. Boca Raton: CRC Press, 275\u2013306."},{"key":"170413_CR10","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0304-4165(72)90241-3","volume":"279","author":"C Ratledge","year":"1972","unstructured":"Ratledge C, Marshall BJ. 1972 Iron transport in Mycobacterium smegmatis: the role of mycobactin. Biochim Biophys Acta\n279, 58\u201374.","journal-title":"Biochim Biophys Acta"},{"key":"170413_CR11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF00205854","volume":"6","author":"R Reissbrodt","year":"1993","unstructured":"Reissbrodt R, Heinisch L, M\u00f6llmann U, Rabsch W, Ulbricht H. 1993 Growth promotion of synthetic catecholate derivatives on Gram-negative bacteria. BioMetals\n6, 155\u2013162.","journal-title":"BioMetals"},{"key":"170413_CR12","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1023\/A:1018327122629","volume":"10","author":"R Reissbrodt","year":"1997","unstructured":"Reissbrodt R, Ramiandrasoa F, Bricard L, Kunesch G. 1997 Siderophore activity of chemically synthesized dihydroxybenzoyl derivatives of spermidines and of cystamide. BioMetals\n10, 95\u2013103.","journal-title":"BioMetals"},{"key":"170413_CR13","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1128\/AAC.10.2.215","volume":"10","author":"MH Richmond","year":"1976","unstructured":"Richmond MH, Clark DC, Wotton S. 1976 Indirect method of assessing the penetration of \u03b2-lactamase-nonsusceptible penicillins and cephalosporins in Escherichia coli strains. Antimicrob Agents Chemother\n10, 215\u2013218.","journal-title":"Antimicrob Agents Chemother"},{"key":"170413_CR14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1128\/AAC.31.4.497","volume":"31","author":"NA Watanabe","year":"1987","unstructured":"Watanabe NA, Nagasu T, Katsu K, Kyosuke K. 1987 E-0702, a new cephalosporin, is incorporated into E. coli cells via the TonB-dependent iron transport system. Antimicrob Agents Chemotherap\n31 497\u2013504.","journal-title":"Antimicrob Agents Chemotherap"},{"key":"170413_CR15","volume-title":"Iron Transport in Microbes, Plants and Animals","author":"G Winkelmann","year":"1987","unstructured":"Winkelmann, G, van der Helm D, Neilands J. 1987 Iron Transport in Microbes, Plants and Animals. VCH Verlagsgesellschaft mbH Weinheim: Germany."},{"key":"170413_CR16","volume-title":"CRC Handbook of Microbial Iron Chelates","author":"G. Winkelmann","year":"1991","unstructured":"Winkelmann G. 1991 Specificity of iron transport in bacteria and fungi. In: Winkelmann G, ed. CRC Handbook of Microbial Iron Chelates. Boca Raton: CRC Press."},{"key":"170413_CR17","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1574-6976.1993.tb00026.x","volume":"12","author":"KG Wooldridge","year":"1993","unstructured":"Wooldridge KG, Williams PH. 1993 Iron uptake mechanisms of pathogenic bacteria. FEMS Microbial Rev\n12, 325\u2013348.","journal-title":"FEMS Microbial Rev"},{"key":"170413_CR18","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF00418640","volume":"36","author":"H Z\u00e4hner","year":"1960","unstructured":"Z\u00e4hner H, Hutter R, Bachmann E. 1960 Zur Kenntnis der Sideromycinwirkung. Arch Mikrobiol\n36, 325\u2013349.","journal-title":"Arch Mikrobiol"},{"key":"170413_CR19","first-page":"131","volume":"17","author":"W. Zimmermann","year":"1979","unstructured":"Zimmermann W. 1979 Penetration through the Gramnegative cell wall: a co-determinant of the efficacy of blactam antibiotics. J Clin Pharmacol Biopharm\n17, 131\u2013134.","journal-title":"J Clin Pharmacol Biopharm"}],"container-title":["Biometals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1009266705308.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1009266705308\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1009266705308.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T17:25:58Z","timestamp":1749576358000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1009266705308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,3]]}},"alternative-id":["170413"],"URL":"https:\/\/doi.org\/10.1023\/a:1009266705308","relation":{},"ISSN":["0966-0844","1572-8773"],"issn-type":[{"value":"0966-0844","type":"print"},{"value":"1572-8773","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,3]]}}}