{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:47:26Z","timestamp":1790394446286,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2001,8,1]],"date-time":"2001-08-01T00:00:00Z","timestamp":996624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,8,1]],"date-time":"2001-08-01T00:00:00Z","timestamp":996624000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2001,8]]},"DOI":"10.1023\/a:1010622125040","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T22:31:49Z","timestamp":1040596309000},"page":"1757-1764","source":"Crossref","is-referenced-by-count":42,"title":["Coordinated Muc2 and Muc3 Mucin Gene Expression in Trichinella spiralis Infection in Wild-Type and Cytokine-Deficient Mice"],"prefix":"10.1007","volume":"46","author":[{"given":"Laurie L.","family":"Shekels","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth E.","family":"Anway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jizhen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm W.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Garside","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine E.","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel B.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"344392_CR1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1365-3024.1992.tb00462.x","volume":"14","author":"P Garside","year":"1992","unstructured":"Garside P, Grencis R, Mowat A: T lymphocyte dependent enteropathy in murine Trichinella spiralis infection.Parasite Immunol14:217\u2013225,1992","journal-title":"Parasite Immunol"},{"key":"344392_CR2","first-page":"480","volume":"81","author":"N Ishikawa","year":"1994","unstructured":"Ishikawa N, Horii Y, Oinuma T, Suganuma T, Nawa Y: Goblet cell mucins as the selective barrier for the intestinal helminths: T-cell-independent alteration of goblet cell mucins by immunologically \u201cdamaged\u201d Nippostrongylus worms and its signifi-cance on the challenge infection with homologous and heterologous parasites.Immunology81:480\u2013486,1994","journal-title":"Immunology"},{"key":"344392_CR3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/0016-5085(94)90057-4","volume":"107","author":"S-Y Chang","year":"1994","unstructured":"Chang S-Y, Dohrman AF, Basbaum CB, Ho SB, Toribara NW, Gum JR, Kim YS: Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer.Gastroenterology107:28\u201336,1994","journal-title":"Gastroenterology"},{"key":"344392_CR4","first-page":"641","volume":"53","author":"SB Ho","year":"1993","unstructured":"Ho SB, Niehans GA, Lyftogt C, Yan P-S, Cherwitz DL, Gum ET, Dahiya R, Kim YS:Heterogeneity of mucin gene expression in normal and neoplastic tissues.Cancer Res53:641\u2013651, 1993","journal-title":"Cancer Res"},{"key":"344392_CR5","doi-asserted-by":"crossref","first-page":"17833","DOI":"10.1016\/S0021-9258(17)32384-0","volume":"269","author":"H Ohmori","year":"1994","unstructured":"Ohmori H, Dohrman AF, Gallup M, Tsuda T, Kai H, Gum JR, Kim YS, Basbaum CB:Molecular cloning of the aminoterminal region of a rat MUC2 mucin gene homologue.J Biol Chem269:17833\u201317840,1994","journal-title":"J Biol Chem"},{"key":"344392_CR6","doi-asserted-by":"crossref","first-page":"5401","DOI":"10.1016\/S0021-9258(18)42780-9","volume":"267","author":"G Xu","year":"1992","unstructured":"Xu G, Huan L-J, Khatri IA, Wang D, Bennick A, Fahim REF, Forstner GG, Forstner JF: cDNA for the carboxyl-terminal region of a rat intestinal mucin-like peptide.J Biol Chem 267:5401\u20135407,1992","journal-title":"J Biol Chem"},{"key":"344392_CR7","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1042\/bj3301301","volume":"330","author":"LL Shekels","year":"1998","unstructured":"Shekels LL, Hunninghake DA, Tisdale AS, Gipson LK, Kieliszewski M, Kozak CA, Ho SB: Cloning and characterization of mouse intestinal MUC3 mucin: 39 sequence contains EGF-like domains.Biochem J 330:1301\u20131308,1998","journal-title":"Biochem J"},{"key":"344392_CR8","first-page":"728","volume":"263","author":"SC Crawley","year":"1999","unstructured":"Crawley SC, Gum JR, Hicks JW, Pratt WS, Aubert JP, Swallow DM, Kim YS:Genomic organization and structure of the 39 region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin. BBRC263:728\u2013736,1999","journal-title":"BBRC"},{"key":"344392_CR9","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1002\/(SICI)1521-4141(199809)28:09<2672::AID-IMMU2672>3.0.CO;2-F","volume":"28","author":"C Lawerence","year":"1998","unstructured":"Lawerence C, Paterson J, Higgins L, MacDonald T, Kennedy M, Garside P: IL-4-regulated enteropathy in an intestinal nematode infection.Eur J Immunol 28:2672\u20132684,1998","journal-title":"Eur J Immunol"},{"key":"344392_CR10","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/S0046-8177(82)80075-0","volume":"13","author":"A Shamsuddin","year":"1982","unstructured":"Shamsuddin A, Phelps P, and Trump B: Human large intestinal epithelium: Light microscopy, histochemistry and ultrastructure. Hum Pathol13:790\u2013795,1982","journal-title":"Hum Pathol"},{"key":"344392_CR11","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1080\/00016489950180432","volume":"119","author":"J Lin","year":"1999","unstructured":"Lin J, Kawano H, Paparella MM, Ho SB: Improved RNA analysis for immediate autopsy of temporal bone soft tissue. Acta Otolaryngol.119:787\u2013795,1999","journal-title":"Acta Otolaryngol."},{"key":"344392_CR12","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1177\/40.8.1352315","volume":"40","author":"JH Carter","year":"1992","unstructured":"Carter JH, Richmond RE, Carter HW, Potter CI, Daniel FB, DeAngelo AB: Quantitative image cytometry of hepatocytes expressing gamma-glutamyl transpeptidase and glutathione Stransferase in diethylnitrosamine-initiated rats treated with phenobarbital and\/or phthalate esters.Journal of Histochemistry and Cytochemistry 40:1105\u20131115,1992","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"344392_CR13","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1165\/ajrcmb.16.4.9115759","volume":"16","author":"UA Temann","year":"1997","unstructured":"Temann UA, Prasad B, Gallup MW, Basbaum C, Ho SB, Flavell RA, Rankin JA: A novel role for murine IL-4 in vivo: Induction of MUC5AC gene expression and mucin hypersecretion. Am. J Cell Mol Biol16:471\u2013478,1997","journal-title":"Am. J Cell Mol Biol"},{"key":"344392_CR14","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1084\/jem.186.10.1737","volume":"186","author":"L Cohn","year":"1997","unstructured":"Cohn L, Homer RJ, Marinov A, Rankin J, Bottomly T: Induction of airway mucus production by T helper (Th2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production.J Exp Med186:1737\u20131747,1997","journal-title":"J Exp Med"},{"key":"344392_CR15","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0008-8749(91)90364-H","volume":"136","author":"V Cohan","year":"1991","unstructured":"Cohan V, Scott A, Dinarello C: Interleukin-1 is a mucus secretagogue.Cell Immunol136:425\u2013434,1991","journal-title":"Cell Immunol"},{"key":"344392_CR16","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1006\/cimm.1993.1243","volume":"151","author":"JW Arnold","year":"1993","unstructured":"Arnold JW, Klimpel GR, Niesel DW:Tumor necrosis factor (TNF alpha) regulates intestinal mucous production during salmonellosis.Cell Immunol151:336\u2013344,1993","journal-title":"Cell Immunol"},{"key":"344392_CR17","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1053\/gast.1997.v113.pm9247474","volume":"113","author":"N Ishikawa","year":"1997","unstructured":"Ishikawa N, Wakelin D, Mahida Y: Role of T helper 2 cells in intestinal goblet cell hyperplasia in mice infected with Trichinella spiralis.Gastroenterology 113:542\u2013549,1997","journal-title":"Gastroenterology"},{"key":"344392_CR18","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1126\/science.282.5397.2261","volume":"282","author":"G Grunig","year":"1998","unstructured":"Grunig G, Warnock M, Wakil A, Venkayya R, Brombacher F, Rennick D, Sheppard D, Mohrs M, Donaldson D, Locksley R, et al:Requirement for IL-13 independently of IL-4 in experimental asthma. Science282:2261\u20132263,1998","journal-title":"Science"},{"key":"344392_CR19","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0960-9822(98)70134-4","volume":"8","author":"G McKenzie","year":"1998","unstructured":"McKenzie G, Bancroft A, Grencis R, McKenzie A: A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Curr Biol8:339\u2013342,1998","journal-title":"Curr Biol"},{"key":"344392_CR20","doi-asserted-by":"crossref","first-page":"000","DOI":"10.1165\/ajrcmb.20.3.3393","volume":"20","author":"B Fischer","year":"1999","unstructured":"Fischer B, Rochelle L, Voynow J, Akley N, Adler K: Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guinea pig tracheal epithelial cells in vitro. Am J Respir Cell Mol Biol 20:000, 1999","journal-title":"Am J Respir Cell Mol Biol"},{"key":"344392_CR21","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1042\/bj3230521","volume":"323","author":"JE Branka","year":"1997","unstructured":"Branka JE, Vallette G, Jarry A, and Laboisse CL: Stimulation of mucin exocytosis from human epithelial cells by nitric oxide: Evidence for a cGMP-dependent and a cGMP-independent pathway. Biochem J 323:521\u2013528, 1997","journal-title":"Biochem J"},{"key":"344392_CR22","doi-asserted-by":"crossref","unstructured":"Lawrence CE, Paterson JCM, Wei X-Q, Liew F-Y, Garside P, Kennedy MW: Nitric oxide mediates intestinal pathology but not immune expulsion during Trichinella spiralis infection in mice.J Immunol2000 (in press)","DOI":"10.4049\/jimmunol.164.8.4229"},{"key":"344392_CR23","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/S0016-5085(96)70009-4","volume":"111","author":"A Belley","year":"1996","unstructured":"Belley A, Keller K, Grove J, Chadee K: Interaction of LS174T human colon cancer cell mucins with Entamoeba histolytica: An in vitro model for colonic disease.Gastroenterology111:1484\u20131492,1996","journal-title":"Gastroenterology"},{"key":"344392_CR24","first-page":"83","volume":"261","author":"SJ Williams","year":"1999","unstructured":"Williams SJ, Munster DJ, Quin RJ, Gotley DC, McGuckin MA: The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.BBRC 261:83\u201389,1999","journal-title":"BBRC"},{"key":"344392_CR25","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1042\/bj3380325","volume":"338","author":"N Moniaux","year":"1999","unstructured":"Moniaux N, Nollet S, Porchet N, Degand P, Laine A, Aubert JP: Complete sequence of the human mucin MUC4: A putative cell membrane-associated mucin.Biochem J338:325\u2013333,1999","journal-title":"Biochem J"},{"key":"344392_CR26","doi-asserted-by":"crossref","first-page":"16341","DOI":"10.1016\/S0021-9258(18)42007-8","volume":"267","author":"Z Sheng","year":"1992","unstructured":"Sheng Z, Wu K, Carraway K, Fregien N: Molecular cloning of the transmembrane component of the 13762 mammary adenocarcinoma sialomucin complex: A new member of the epidermal growth factor superfamily.J Biol Chem 267:16341\u201316346, 1992","journal-title":"J Biol Chem"},{"key":"344392_CR27","doi-asserted-by":"crossref","first-page":"11950","DOI":"10.1016\/S0021-9258(17)32665-0","volume":"269","author":"K Wu","year":"1994","unstructured":"Wu K, Fregien N, Carraway KL: Molecular cloning and sequencing of the mucin subunit of a heterodimeric, bifunctional cell surface glycoprotein complex of ascites rat mammary adenocarcinoma cell.J Biol Chem 269:11950\u201311955,1994","journal-title":"J Biol Chem"},{"key":"344392_CR28","doi-asserted-by":"crossref","first-page":"33476","DOI":"10.1074\/jbc.271.52.33476","volume":"271","author":"EA Rossi","year":"1996","unstructured":"Rossi EA, McNeer RR, Price-Schiavi S, Van den Brande JMH, Komatsu M, Thompson JF, Carraway CAC, Fregien NL, Carraway KL: Sialomucin complex, a heterodimeric glycoprotein complex: expression as a soluble secretable form in lactating mammary gland and colon.J Biol Chem271:33476\u201333485, 1996","journal-title":"J Biol Chem"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1010622125040.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1010622125040\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1010622125040.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T04:08:05Z","timestamp":1753762085000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1010622125040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8]]},"references-count":28,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2001,8]]}},"alternative-id":["344392"],"URL":"https:\/\/doi.org\/10.1023\/a:1010622125040","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,8]]}}}