{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T16:51:02Z","timestamp":1789923062766,"version":"4.0.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Epidemiol"],"published-print":{"date-parts":[[2000,11]]},"DOI":"10.1023\/a:1010895227352","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T23:10:54Z","timestamp":1040598654000},"page":"1009-1016","source":"Crossref","is-referenced-by-count":8,"title":["Plasma retinol and tocopherol levels in Greek elderly population from an urban and a rural area: Associations with the dietary habits"],"prefix":"10.1007","volume":"16","author":[{"given":"M.","family":"Leotsinidis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Alexopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Schinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kardara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Kondakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"333037_CR1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/geronj\/16.3.247","volume":"16","author":"D Harrman","year":"1961","unstructured":"Harrman D. Prolongation of the normal lifespan and inhibition of spontaneous cancer by antioxidants. J Gerontol 16 1961; 16: 247\u2013254.","journal-title":"J Gerontol 16"},{"key":"333037_CR2","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1093\/ajcn\/45.5.1368","volume":"45","author":"KF Gey","year":"1987","unstructured":"Gey KF, Brubacher GB, Stahelin HB. Plasma levels of antioxidant vitamins in relation to ischemic heart disease. Am J Clin Nutr 1987; 45: 1368\u20131377.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR3","doi-asserted-by":"crossref","first-page":"S326","DOI":"10.1093\/ajcn\/53.1.326S","volume":"53","author":"KF Gey","year":"1991","unstructured":"Gey KF, Puska P, Jordan P, Moser UK. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. Am J Clin Nutr 1991; 53: S326-S334.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR4","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1056\/NEJM199305203282004","volume":"328","author":"EB Rimm","year":"1993","unstructured":"Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willet WC. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 1993; 328: 1450\u20131456.","journal-title":"N Engl J Med"},{"key":"333037_CR5","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1093\/ije\/21.4.625","volume":"21","author":"J Chen","year":"1992","unstructured":"Chen J, Geissler C, Parpia B, Li J, Campell TC. Antioxidant status and cancer mortality in China. Int J Epidemiol 1992; 21: 625\u2013635.","journal-title":"Int J Epidemiol"},{"key":"333037_CR6","first-page":"411","volume":"62","author":"M Meydani","year":"1992","unstructured":"Meydani M. Vitamin E requirement in relation to dietary fish oil and oxidative stress in elderly. EXS 1992; 62: 411\u2013418.","journal-title":"EXS"},{"key":"333037_CR7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/jn\/126.1.129","volume":"126","author":"WE Brady","year":"1996","unstructured":"Brady WE, Marles-Perlman JA, Bower P, Stacewicz-Sapumtzakis M. Human serum carotenoid concentrations are related to physiologic and lifestyle factors. J Nutr 1996; 126: 129\u2013137.","journal-title":"J Nutr"},{"key":"333037_CR8","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/oxfordjournals.aje.a114771","volume":"127","author":"B Olmedilla","year":"1988","unstructured":"Olmedilla B, Granado F, Blanco I, Rojas-Hidalgo E. Seasonal and sex-related variations in six serum carotenoids, retinol and \u03b1-tocopherol in older adults. Am J Epidemiol 1988; 127: 114\u2013123.","journal-title":"Am J Epidemiol"},{"key":"333037_CR9","first-page":"63","volume":"45","author":"Euronut SENECA investigators.","year":"1991","unstructured":"Euronut SENECA investigators. Nutritional status: Blood vitamins A, E, B6, B12, folic acid and carotene. Eur J Clin Nutr 1991; 45: 63\u201382.","journal-title":"Eur J Clin Nutr"},{"key":"333037_CR10","first-page":"349","volume":"57","author":"M Porrini","year":"1987","unstructured":"Porrini M, Simonetti P, Ciappellano S, Testolin G. Vitamin A, E and C nutriture of elderly people in North Italy. Int J Vit Nutr Res 1987; 57: 349\u2013355.","journal-title":"Int J Vit Nutr Res"},{"key":"333037_CR11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0003-2697(85)90321-5","volume":"145","author":"KW Miller","year":"1985","unstructured":"Miller KW, Yang CS. An isocratic high-performance liquid chromatography method for the simultaneous analysis of plasma retinol, \u03b1-tocopherol and various carotenoids. Anal Biochem 1985; 145: 21\u201326.","journal-title":"Anal Biochem"},{"key":"333037_CR12","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ije\/26.2.307","volume":"26","author":"Y Kitamura","year":"1997","unstructured":"Kitamura Y, Tanaka K, Kiyohara C, et al. Relationship of alcohol use and dietary habits with serum carotenoids, retinol and \u03b1-tocopherol among Japanese smokers. Int J Epidemiol 1997; 26: 307\u2013314.","journal-title":"Int J Epidemiol"},{"key":"333037_CR13","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1093\/oxfordjournals.aje.a115577","volume":"131","author":"I Romieu","year":"1990","unstructured":"Romieu I, Stampfer MJ, Stryker WS, et al. Food predictors of plasma b-carotene and a-tocopherol: Validation of a food frequency questionnaire. Am J Epidemiol 1990; 131: 864\u2013876.","journal-title":"Am J Epidemiol"},{"key":"333037_CR14","first-page":"151","volume":"65","author":"V Azais-Braesco","year":"1995","unstructured":"Azais-Braesco V, Moriniere C, Guesne B, et al. Vitamin A status in the institutionalized elderly. Critical analysis of four evaluation criteria: Dietary vitamin A intake, serum retinol, relative dose-response test (RDR) and impression cytology with transfer (ICT). Int J Vit Nutr Res 1995; 65: 151\u2013161.","journal-title":"Int J Vit Nutr Res"},{"key":"333037_CR15","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/978-94-011-7321-6_18","volume-title":"The Vitamins: Their Role in Medical Practice","author":"J Marks","year":"1985","unstructured":"Marks J. The Vitamins: Their Role in Medical Practice. NY: MTP Press, 1985, pp 111\u2013112."},{"key":"333037_CR16","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/ajcn\/49.2.358","volume":"49","author":"A Bendich","year":"1989","unstructured":"Bendich A, Langseth L. Safety of Vitamin A. Am J Clin Nutr 1989; 49: 358\u2013371.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR17","doi-asserted-by":"crossref","first-page":"B98","DOI":"10.1093\/geronj\/47.3.B98","volume":"47","author":"M Panemangalore","year":"1992","unstructured":"Panemangalore M, Lee JC. Evaluation of the indices of retinol and a-tocopherol status in free living elderly. J Gerontol 1992; 47: B98-B104.","journal-title":"J Gerontol"},{"key":"333037_CR18","first-page":"175","volume":"43","author":"B Herberth","year":"1989","unstructured":"Herberth B, Chavance M, Musse N, Mejean L. Dietary intake and other determinants of blood vitamins in an elderly population. Eur J Clin Nutr 1989; 43: 175\u2013186.","journal-title":"Eur J Clin Nutr"},{"key":"333037_CR19","unstructured":"Heseker H, Schneider R, Moch KJ, Kohlmeier M, Kubler W. Vitamins status of adults in the Federal Republic of Germany. Vera Schriftenreihe-Band IV. Niederkleen, Germany. 1992 Wissenschaflicher Fachverlag Dr Fleck."},{"key":"333037_CR20","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1093\/ajcn\/60.2.176","volume":"60","author":"J Hallfrisch","year":"1994","unstructured":"Hallfrisch J, Muller D, Singh V. Vitamin A and E intakes and plasma concentrations of retinol, b-carotene, and a-tocopherol in men and women of the Baltimore longitudinal study of aging. Am J Clin Nutr 1994; 60: 176\u2013182.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR21","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1093\/jn\/117.4.636","volume":"117","author":"SM Pilch","year":"1987","unstructured":"Pilch SM. Analysis of vitamin A data from the Health and Examination Surveys. J Nutr 1987; 117: 636\u2013640.","journal-title":"J Nutr"},{"key":"333037_CR22","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1093\/ajcn\/46.6.989","volume":"46","author":"PJ Garry","year":"1987","unstructured":"Garry PJ, Hunt WC, Brandrofchack JL, Vanderjagt D, Goodwin JS. Vitamin A intake and plasma retinol levels in healthy elderly men and women. Am J Clin Nutr 1987; 46: 989\u2013994.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR23","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1093\/ajcn\/57.2.182","volume":"57","author":"PF Jacques","year":"1993","unstructured":"Jacques PF, Sulsky SI, Sadowski JA, Phillips JCC, Rush D, Willett WC. Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micronutrient status. Am J Clin Nutr 1993; 57: 182\u2013189.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR24","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1093\/ajcn\/48.6.1490","volume":"48","author":"AC Looker","year":"1988","unstructured":"Looker AC, Johnson CL, Underwood BA. Serum retinol levels of persons aged 4\u201374 years from three Hispanic groups. Am J Clin Nutr 1988; 48: 1490\u20131496.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/ajcn\/49.1.112","volume":"49","author":"SD Krasinski","year":"1989","unstructured":"Krasinski SD, Rusell RM, Otradovec CL. Relationship of vitamin A and E intake to fasting plasma retinol, retinol binding protein, retinyl esters, carotene, \u03b1-tocopherol and cholesterol among elderly people and young adults: Increased plasma retinyl esters among vitamin A supplement users. Am J Clin Nutr 1989; 49: 112\u2013120.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR26","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/ajcn\/30.3.431","volume":"30","author":"I Harrell","year":"1997","unstructured":"Harrell I, Cervone N. Vitamin status of older women. Am J Clin Nutr 1997; 30: 431\u2013440.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR27","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1093\/ajcn\/66.4.950","volume":"66","author":"S Vogel","year":"1997","unstructured":"Vogel S, Contois J, Tucker K, Wilson P, Schaefer E, Keefe-Lammi CJ. Plasma retinol and plasma and lipoprotein tocopherol and carotenoid concentrations in health elderly participants of the Framingham Heart Study. Am J Clin Nutr 1997; 66: 950\u2013958.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR28","first-page":"71","volume":"66","author":"AL Monget","year":"1996","unstructured":"Monget AL, Galan P, Preziosi P, et al. Micronutrients status in elderly population. Int J Vit Nutr Res 1996; 66: 71\u201376.","journal-title":"Int J Vit Nutr Res"},{"key":"333037_CR29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0009-8981(90)90128-F","volume":"194","author":"Y Ito","year":"1990","unstructured":"Ito Y, Ochiai J, Sasaki R, et al. Serum concentrations of carotenoids, retinol and a-tocopherol in healthy persons determined by HPLC. Clinica Chimica Acta 1990; 194: 131\u2013144.","journal-title":"Clinica Chimica Acta"},{"key":"333037_CR30","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/oxfordjournals.aje.a114771","volume":"127","author":"GW Comstock","year":"1987","unstructured":"Comstock GW, Menkes MS, Schober SE, Vuilleumier JP, Helsing KJ. Serum levels of retinol, b-carotene and \u03b1-tocopherol in older adults. Am J Epidemiol 1987; 127: 114\u2013123.","journal-title":"Am J Epidemiol"},{"key":"333037_CR31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00043798-199406000-00003","volume":"1","author":"A Trichopoulou","year":"1994","unstructured":"Trichopoulou A, Lagiou P, Trichopoulos D. Traditional Greek diet and coronary heart disease. J Cardiovascular Risk 1994; 1: 9\u201315.","journal-title":"J Cardiovascular Risk"},{"key":"333037_CR32","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/00007611-198710000-00004","volume":"80","author":"MP Thompson","year":"1987","unstructured":"Thompson MP, Mongan PF, Miller MD, Creten D. Comparison of dietary intake of urban and rural elderly patients in family practice centers. Southern Med J 1987; 80: 1216\u20131219.","journal-title":"Southern Med J"},{"key":"333037_CR33","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1080\/07315724.1987.10720192","volume":"6","author":"MF Vandewoude","year":"1987","unstructured":"Vandewoude MF, Vandewoude MG. Vitamin E status in normal population: The influence of age. J Am Coll Nutr 1987; 6: 307\u2013311.","journal-title":"J Am Coll Nutr"},{"key":"333037_CR34","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/oxfordjournals.aje.a114788","volume":"127","author":"P Knekt","year":"1988","unstructured":"Knekt P, Aromaa A, Maatela J. Serum vitamin E and risk of cancer among Finnish men during a 10-year follow-up. Am J Epidemiol 1988; 127: 28\u201341.","journal-title":"Am J Epidemiol"},{"key":"333037_CR35","first-page":"412","volume":"53","author":"P Hooper","year":"1983","unstructured":"Hooper P, Hooper E, Hunt W, Garry P, Goodwin J. Vitamins, lipids and lipoproteins in a health elderly population. Int J Vit Nutr Res 1983; 53: 412\u2013419.","journal-title":"Int J Vit Nutr Res"},{"key":"333037_CR36","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1093\/ageing\/8.3.177","volume":"8","author":"CJ Bates","year":"1979","unstructured":"Bates CJ, Burr MK, Leger AS. Vitamin C, high density lipoproteins and heart disease in elderly subjects. Age Ageing 1979; 8: 177\u2013182.","journal-title":"Age Ageing"},{"key":"333037_CR37","first-page":"399","volume":"36C","author":"ML Burr","year":"1982","unstructured":"Burr ML, Bates CJ, Sweetnam PM, Barasi ME. Plasma ascorbate and HDL-cholesterol in women. Hum Nutr Clin Nutr 1982; 36C: 399\u2013400.","journal-title":"Hum Nutr Clin Nutr"},{"key":"333037_CR38","first-page":"406","volume":"49","author":"E Ginter","year":"1979","unstructured":"Ginter E, Kubec FJ, Vozar J, Boker P. Natural hypocholesterolemic agent: Pectin plus ascorbic acid. Int J Vitam Nutr Res 1979; 49: 406\u2013412.","journal-title":"Int J Vitam Nutr Res"},{"key":"333037_CR39","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1093\/ajcp\/77.1.86","volume":"77","author":"DR Howard","year":"1982","unstructured":"Howard DR, Rundell CA, Batsakis JG. Vitamin E does not modify HDL-cholesterol. Am J Clin Pathol 1982; 77: 86\u201389.","journal-title":"Am J Clin Pathol"},{"key":"333037_CR40","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1093\/ajcn\/34.10.2088","volume":"34","author":"GE Johnson","year":"1981","unstructured":"Johnson GE, Obenshain SS. Nonresponsiveness of serum high-density lipoprotein-cholesterol to high dose ascorbic acid administration in normal men. Am J Clin Nutr 1981; 34: 2088\u20132091.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR41","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/ajcp\/76.6.843","volume":"76","author":"PL Schwartz","year":"1981","unstructured":"Schwartz PL, Rutherford IM. The effect of tocopherol on high-density lipoprotein cholesterol. Am J Clin Pathol 1981; 76: 843\u2013845.","journal-title":"Am J Clin Pathol"},{"key":"333037_CR42","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/ajcn\/28.6.584","volume":"28","author":"VE Peterson","year":"1975","unstructured":"Peterson VE, Crapo PA, Weininger J, Ginsberg H, Olefsky L. Quantification of plasma cholesterol and triglyceride levels in hypercholesterolemic subjects receiving ascorbic acid supplements. Am J Clin Nutr 1975; 28: 584\u2013587.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR43","first-page":"297","volume":"5","author":"LA Kaplan","year":"1987","unstructured":"Kaplan LA, Stein EA, Willett WC, Stampfer MJ, Stryker WS. Reference ranges of retinol, tocopherols, lycopene and a-and b-carotene in plasma by simultaneous HPLC analysis. Clin Physiol Biochem 1987; 5: 297\u2013304.","journal-title":"Clin Physiol Biochem"},{"key":"333037_CR44","first-page":"266","volume":"53","author":"JP Vuilleumier","year":"1983","unstructured":"Vuilleumier JP, Keller HE, Gysel D. Clinical chemical methods for the routine assessment of the vitamin status in human populations. Part I: The fat soluble vitamins A and E and \u03b2-carotene. Int J Vit Nutr Res 1983; 53: 266\u2013272.","journal-title":"Int J Vit Nutr Res"},{"key":"333037_CR45","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1093\/ajcn\/35.5.1142","volume":"35","author":"BB Bowman","year":"1982","unstructured":"Bowman BB, Rosenberg IH. Assessment of the nutritional status of the elderly. Am J Clin Nutr 1982; 35: 1142\u20131151.","journal-title":"Am J Clin Nutr"},{"key":"333037_CR46","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/ageing\/20.6.413","volume":"20","author":"M Succari","year":"1991","unstructured":"Succari M, Garric B, Ponteziere C, Miocque M, Cals MJ. Influence of sex and age on vitamin A and E status. Age Ageing 1991; 20: 413\u2013416.","journal-title":"Age Ageing"}],"container-title":["European Journal of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1010895227352.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1010895227352\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1010895227352.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T05:02:35Z","timestamp":1753851755000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1010895227352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":46,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["333037"],"URL":"https:\/\/doi.org\/10.1023\/a:1010895227352","relation":{},"ISSN":["0393-2990","1573-7284"],"issn-type":[{"value":"0393-2990","type":"print"},{"value":"1573-7284","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,11]]}}}