{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:10:09Z","timestamp":1790507409939,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Epidemiol"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1023\/a:1010979522339","type":"journal-article","created":{"date-parts":[[2002,12,22]],"date-time":"2002-12-22T23:10:54Z","timestamp":1040598654000},"page":"77-84","source":"Crossref","is-referenced-by-count":17,"title":["The distribution in specific IgE and the prevalence of allergic symptoms in25\u201364-years old inhabitants of an eastern and a western German city \u2013 Results from Augsburg and Erfurt"],"prefix":"10.1007","volume":"17","author":[{"given":"B.","family":"Filipiak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Heinrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.-E.","family":"Wichmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"351707_CR1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1183\/09031936.94.07050954","volume":"7","author":"P Burney","year":"1994","unstructured":"Burney P, et al. for ECRHS. The European Community Respiratory Health Survey. European study protocols. Eur Respir J 1994; 7: 954-960.","journal-title":"Eur Respir J"},{"key":"351707_CR2","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1183\/09031936.96.09040687","volume":"9","author":"P Burney","year":"1996","unstructured":"Burney P, et al. for ECRHS. Variations in the prevalence of respiratory symptoms, selfreported asthma attacks, and the use of asthma medication in the European Community Respiratory Health Survey (ECRHS). Eur Respir J 1996; 9: 687-695.","journal-title":"Eur Respir J"},{"key":"351707_CR3","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0091-6749(97)70048-4","volume":"99","author":"P Burney","year":"1997","unstructured":"Burney P, et al. for ECRHS. The distribution of total and specific serum IgE in the European Community Respiratory Health Survey. J Allergy Clin Immunol 1997; 99: 314-322.","journal-title":"J Allergy Clin Immunol"},{"key":"351707_CR4","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1183\/09031936.96.09122541","volume":"9","author":"D Nowak","year":"1996","unstructured":"Nowak D, Heinrich J, J\u00f6rres R, et al. Prevalence of respiratory symptoms, bronchial hyperresponsiveness and atopy among adults: West and East Germany. Eur Respir J 1996; 9: 2541-2552.","journal-title":"Eur Respir J"},{"key":"351707_CR5","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/S0140-6736(97)07302-9","volume":"351","author":"R Beasley","year":"1998","unstructured":"Beasley R, Keil U, von Mutius E, Pearce N for ISAAC. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 1998; 351: 1225-1232.","journal-title":"Lancet"},{"key":"351707_CR6","first-page":"104","volume":"41","author":"WHO MONICA Project Principal Investigators.","year":"1988","unstructured":"WHO MONICA Project Principal Investigators (prep. by Tunstall-Pedoe, H). The World Health Organization MONICA Project. A major international collaboration. J Clin Epidemiol 1988; 41: 104-114.","journal-title":"J Clin Epidemiol"},{"key":"351707_CR7","series-title":"GSF-Bericht","volume-title":"Data-Book. MONICA Project Augsburg","author":"B Filipiak","year":"1997","unstructured":"Filipiak B, Schneider A, D\u00f6ring A, Sticber J, Keil U. Trends in cardiovascular risk factors from survey 1984\/85 to 1994\/95. Data-Book. MONICA Project Augsburg. GSF-Bericht 27\/97. Neuherberg: GSF, 1997."},{"key":"351707_CR8","first-page":"539","volume":"11","author":"J Heinrich","year":"1995","unstructured":"Heinrich J, Beck E, Wassmer G, Wichmann HE. Die H\u00e4ufigkeit von Asthma, Atemwegssymptomen und von allergischer Rhinitis bei Erwachsenen in einer ostdeutschen Gro\u00dfstadt. Allergologie 1995; 11: 539-646.","journal-title":"Allergologie"},{"key":"351707_CR9","volume-title":"Methods in Epidemiology","author":"J. Fleiss","year":"1980","unstructured":"Fleiss J. Methods in Epidemiology. New York: Wily, 1980."},{"key":"351707_CR10","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1023\/A:1007465205976","volume":"14","author":"J Heinrich","year":"1998","unstructured":"Heinrich J, Richter K, Magnussen H, Wichmann HE. Is the prevalence of atopic diseases in East and West Germany already converging? Eur J Epidemiol 1998; 14: 239-245.","journal-title":"Eur J Epidemiol"},{"key":"351707_CR11","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1183\/09031936.94.07122139","volume":"7","author":"R de Marco","year":"1994","unstructured":"de Marco R, Verlato G, Zanolin E, Bugiani M, Drane JW. Nonresponse bias in EC Respiratory Health Survey in Italy. Eur Respir J 1994; 7: 2139-2145.","journal-title":"Eur Respir J"},{"key":"351707_CR12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1515\/REVEH.1996.11.3.119","volume":"11","author":"MJ Trepka","year":"1996","unstructured":"Trepka MJ, Heinrich J, Wichmann HE. The epidemiology of atopic diseases in Germany: An East-West comparison. Rev Environ Health 1996; 11: 119-131.","journal-title":"Rev Environ Health"},{"key":"351707_CR13","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1164\/ajrccm.149.2.8306030","volume":"149","author":"E von Mutius","year":"1994","unstructured":"von Mutius E, Martinez FD, Fritsch C, Nicolai T, R\u00f6ll G, Thiemann HH. Prevalence of asthma and atopy in two areas of West and East Germany. Am J Respir Crit Care Med 1994; 149: 358-364.","journal-title":"Am J Respir Crit Care Med"},{"key":"351707_CR14","first-page":"25","volume-title":"New Trends in Allergy IV","author":"U Kr\u00e4mer","year":"1996","unstructured":"Kr\u00e4mer U, Behrendt H, Ring J. Air pollution as a risk factor for allergy \u2014 The east-west German experience. In: Ring J (ed.), New Trends in Allergy IV, Berlin: Springer, 1996: 25-35."},{"key":"351707_CR15","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1111\/j.1365-2222.1997.tb01228.x","volume":"27","author":"T Nicolai","year":"1997","unstructured":"Nicolai T, Bellach B, V Mutius E, Thefeld W, Hoffmeister H. Increased prevalence of sensitization against aeroallergens in adults in West and East Germany. Clin Exp Allergy 1997; 27: 886-892.","journal-title":"Clin Exp Allergy"},{"key":"351707_CR16","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/j.1365-2222.1994.tb01805.x","volume":"24","author":"L Braback","year":"1994","unstructured":"Braback L, Breborowicz A, Dreborg S, Knutsson A, Pieklik H, Bj\u00f6rksten B. Atopic sensitization and respiratory symptoms among Polish and Swedish school children. Clin Exp Allergy 1994; 24: 826-835.","journal-title":"Clin Exp Allergy"},{"key":"351707_CR17","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1046\/j.1365-2222.1998.00366.x","volume":"28","author":"R J\u00f6gi","year":"1998","unstructured":"J\u00f6gi R, Janson C, Bj\u00f6rnsson E, Boman G, Bj\u00f6rksten B. Atopy and allergic disorders among adults in Tartu, Estonia compared with Uppsala, Sweden. Clin Exp Allergy 1998; 28: 1072-1080.","journal-title":"Clin Exp Allergy"},{"key":"351707_CR18","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/j.1365-2222.1996.tb00587.x","volume":"26","author":"HE. Wichmann","year":"1996","unstructured":"Wichmann HE. Possible explanation for the different trends of asthma and allergy in East and West Germany. Clin Exp Allergy 1996; 26: 621-623.","journal-title":"Clin Exp Allergy"},{"key":"351707_CR19","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1046\/j.1365-2222.1998.00373.x","volume":"28","author":"D Nowak","year":"1998","unstructured":"Nowak D, Wichmann HE, Magnussen H. Asthma and atopy in western and eastern communities current status and open questions. Clin Exp Allergy 1998; 28: 1043-1046.","journal-title":"Clin Exp Allergy"},{"key":"351707_CR20","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0140-6736(98)06329-6","volume":"353","author":"U Kr\u00e4mer","year":"1999","unstructured":"Kr\u00e4mer U, Heinrich J, Wjst M, Wichmann HE. Age of entry to day nursery and allergy in later childhood. Lancet 1999; 353: 450-454.","journal-title":"Lancet"},{"key":"351707_CR21","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1016\/S0140-6736(99)01609-8","volume":"353","author":"SK Weiland","year":"1999","unstructured":"Weiland SK, von Mutius E, H\u00fcsing A, Asher MI. Intake of trans fatty acids and prevalence of childhood asthma and allergies in Europe. ISAAC Steering Committee. Research Letter. Lancet 1999; 353: 2040-2041.","journal-title":"Lancet"},{"key":"351707_CR22","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1016\/S0140-6736(05)78777-8","volume":"351","author":"J Heinrich","year":"1998","unstructured":"Heinrich J, Wjst M. Increase of allergy in East Germany, Letter. Lancet 1998; 351: 1813.","journal-title":"Lancet"},{"key":"351707_CR23","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/S0140-6736(97)10100-3","volume":"351","author":"E von Mutius","year":"1998","unstructured":"von Mutius E, Weiland SK, Fritzsch C, Duhme H, Keil U. Increasing prevalence of hay fever and atopy among children in Leipzig, East Germany. Lancet 1998; 351: 862-866.","journal-title":"Lancet"},{"key":"351707_CR24","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1034\/j.1399-3003.1999.14d23.x","volume":"14","author":"SK Weiland","year":"1999","unstructured":"Weiland SK, von Mutius E, Hirsch T, et al. Prevalence of respiratory and atopic disorders among children in the East and West of Germany five years after unification. Eur Respir J 1999; 14: 862-870.","journal-title":"Eur Respir J"},{"key":"351707_CR25","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1159\/000237398","volume":"111","author":"B W\u00fcthrich","year":"1996","unstructured":"W\u00fcthrich B, Schindler C, Medici TC, Zellweger JP, Leuenberger P and the SAPALDIA-team. IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population. Int Arch Allergy Immunol 1996; 111: 396-402.","journal-title":"Int Arch Allergy Immunol"},{"key":"351707_CR26","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0954-6111(95)90136-1","volume":"89","author":"F Neukirch","year":"1995","unstructured":"Neukirch F, Pin I, et al. Prevalence of asthma and asthma-like symptoms in three French cities. Respir Med 1995; 89: 685-692.","journal-title":"Respir Med"},{"key":"351707_CR27","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/S0091-6749(96)80066-2","volume":"97","author":"JHJ Droste","year":"1996","unstructured":"Droste JHJ, Kerkhoff M, de Monchy JGR, Schouten JP, Rijcken B and the Dutch ECRHS Group. Association of skin test reactivity, specific IgE, total IgE, and eosinophils with nasal symptoms in a community-based population study. J Allergy Clin Immunol 1996; 97: 922-932.","journal-title":"J Allergy Clin Immunol"},{"key":"351707_CR28","first-page":"770","volume":"51","author":"M Kerkhof","year":"1996","unstructured":"Kerkhof M, Droste JH, de Monchy JG, Schouten JP, Rijcken B. Distribution of total IgE and specific IgE to common aeroallergens by sex and age, and their relationship to each other in a random sample of the Dutch general population aged 20\u201370 years. Dutch ECRHS Group, European Community Respiratory Health Study. Allergy 1996; 51: 770-776.","journal-title":"Allergy"},{"key":"351707_CR29","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/j.1365-2222.1994.tb00950.x","volume":"44","author":"E Omenaas","year":"1994","unstructured":"Omenaas E, Bakke P, Elsayed S, Hanoa R, Gulsvik A. Total and specific IgE levels in adults relationship to sex, age and environmental factors. Clin Exp Allergy 1994; 44: 530-539.","journal-title":"Clin Exp Allergy"},{"key":"351707_CR30","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1183\/09031936.97.10071460","volume":"10","author":"MH Wieringa","year":"1997","unstructured":"Wieringa MH, Weyler JJ, Van Bastelaer FJ, Nelen VJ, Van Sprundel MP, Vermeire PA. Higher asthma occurrence in a urban than a suburban area: Role of house dust mite skin allergy. Eur Respir J 1997; 10: 1460-1466.","journal-title":"Eur Respir J"},{"key":"351707_CR31","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1398-9995.1996.tb00094.x","volume":"51","author":"R J\u00f6gi","year":"1996","unstructured":"J\u00f6gi R, Janson C, Bj\u00f6rnsson E, Boman G, Bj\u00f6rksten B. The prevalence of asthmatic respiratory symptoms among adults in Estonian and Swedish university cities. Allergy 1996; 51: 331-336.","journal-title":"Allergy"},{"key":"351707_CR32","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0091-6749(87)90286-7","volume":"80","author":"PJ Gergen","year":"1987","unstructured":"Gergen PJ, Turkeltaub PC, Kovar MG. The prevalence of allergic skin test reactivity to eight common aeroallergens in the U.S. population: Results from the second National Health and Nutrition examination Survey. J Allergy Clin Immunol 1987; 80: 669-679.","journal-title":"J Allergy Clin Immunol"},{"key":"351707_CR33","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1001\/archinte.1991.00400030053009","volume":"151","author":"PJ Gergen","year":"1991","unstructured":"Gergen PJ, Turkeltaub PC. The association of allergen skin test reactivity and respiratory disease among whites in the US population. Data from the second National Health and Nutrition examination Survey 1976 to 1980. Arch Intern Med 1991; 151: 487-492.","journal-title":"Arch Intern Med"}],"container-title":["European Journal of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1010979522339.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1010979522339\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1010979522339.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T05:16:46Z","timestamp":1753852606000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1010979522339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["351707"],"URL":"https:\/\/doi.org\/10.1023\/a:1010979522339","relation":{},"ISSN":["0393-2990","1573-7284"],"issn-type":[{"value":"0393-2990","type":"print"},{"value":"1573-7284","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}