{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T07:06:13Z","timestamp":1771484773936,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Thromb Thrombolysis"],"published-print":{"date-parts":[[2001,4]]},"DOI":"10.1023\/a:1011280801335","type":"journal-article","created":{"date-parts":[[2002,12,23]],"date-time":"2002-12-23T04:18:21Z","timestamp":1040617101000},"page":"155-162","source":"Crossref","is-referenced-by-count":7,"title":["Usefulness of Combining Necrosis and Platelet Markers in Triaging Patients Presenting with Chest Pain to the Emergency Department"],"prefix":"10.1007","volume":"11","author":[{"given":"Victor L.","family":"Serebruany","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas J.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girish V.","family":"Nair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew F.","family":"Meister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Gurbel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"338786_CR1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0009-8981(97)00250-7","volume":"272","author":"R. Roberts","year":"1998","unstructured":"Roberts R. Early diagnosis of myocardial infarction with MB CK isoforms. Clin Chim Acta 1998;272:33\u201345.","journal-title":"Clin Chim Acta"},{"key":"338786_CR2","first-page":"122","volume":"32","author":"T Millane","year":"1998","unstructured":"Millane T, Hearing SD, Jones PE, Brooks NH. Two ECGs and a history: a guide to early hospital discharge of patients with \u2018chest pain cause\u2019. J R Coll Physicians Lond 1998;32:122\u2013124.","journal-title":"J R Coll Physicians Lond"},{"key":"338786_CR3","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0196-0644(05)80057-5","volume":"21","author":"JR Hedges","year":"1992","unstructured":"Hedges JR, Young GP, Henkel GF, Gibler WB, Green TR, Swanson JR. Serial ECGs are less accurate than serial CK-MB results for emergency department diagnosis of myocardial infarction. Ann Emerg Med 1992;21:1445\u20131450.","journal-title":"Ann Emerg Med"},{"key":"338786_CR4","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1161\/01.CIR.92.12.3401","volume":"92","author":"RJ de Winter","year":"1995","unstructured":"de Winter RJ, Koster RW, Sturk A, Sanders GT. Value of myoglobin, troponin T, and CK-MB mass in ruling out an acute myocardial infarction in the emergency room. Circulation 1995;92:3401\u20133407.","journal-title":"Circulation"},{"key":"338786_CR5","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0196-0644(98)70200-8","volume":"31","author":"MC Kontos","year":"1998","unstructured":"Kontos MC, Arrowood JA, Paulsen WH, Nixon JV. Early echocardiography can predict cardiac events in emergency department patients with chest pain. Ann Emerg Med 1998;31:550\u2013557.","journal-title":"Ann Emerg Med"},{"key":"338786_CR6","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0009-8981(97)00254-4","volume":"272","author":"J. Mair","year":"1998","unstructured":"Mair J. Glycogen phosphorylase isoenzyme BB to diagnose ischaemic myocardial damage. Clin Chim Acta 1998;272:79\u201386.","journal-title":"Clin Chim Acta"},{"key":"338786_CR7","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1053\/hj.1999.v137.92412","volume":"137","author":"A Falahati","year":"1999","unstructured":"Falahati A, Sharkey SW, Christensen D, McCoy M, Miller EA, Murakami MA, Apple FS. Implementation of serum cardiac troponin I as marker for detection of acute myocardial infarction. Am Heart J 1999;137:332\u2013337.","journal-title":"Am Heart J"},{"key":"338786_CR8","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1161\/01.CIR.99.13.1671","volume":"99","author":"J Zimmerman","year":"1999","unstructured":"Zimmerman J, Fromm R, Meyer D, et al. Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation 1999;99:1671\u20131677.","journal-title":"Circulation"},{"key":"338786_CR9","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1056\/NEJM199409013310901","volume":"331","author":"PR Puleo","year":"1994","unstructured":"Puleo PR, Meyer D, Wahten C, et al. Use of a rapid assay of subforms of creatine kinase MB to diagnose or rule out acute myocardial infarction. N Engl J Med 1994;331:561\u2013566.","journal-title":"N Engl J Med"},{"key":"338786_CR10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0735-1097(99)00175-8","volume":"34","author":"JE Hollander","year":"1999","unstructured":"Hollander JE, Muttreja MR, Dalesandro MR, Shofer FS. Risk stratification of emergency department patients with acute coronary syndromes using P-selectin. J Am Coll Cardiol 1999;34:95\u2013105.","journal-title":"J Am Coll Cardiol"},{"key":"338786_CR11","doi-asserted-by":"crossref","unstructured":"Gurbel PA, Kereiakes DJ, Dalesandro MR, Bahr RD, O'Connor CM, Serebruany VL. The role of soluble and platelet-bound P-selectin in discriminating cardiac from non-cardiac chest pain at presentation in the emergency department. Amer Heart J 2000;(in press).","DOI":"10.1067\/mhj.2000.101109"},{"key":"338786_CR12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0049-3848(99)00063-8","volume":"96","author":"VL Serebruany","year":"1999","unstructured":"Serebruany VL, Kereiakes DJ, Dalesandro MR, Gurbel PA. Model of flow cytometer markedly affects platelet-bound P-selectin expression in patients with chest pain. Are we comparing apples with oranges? Thromb Res 1999;96:51\u201356.","journal-title":"Thromb Res"},{"key":"338786_CR13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/radiology.143.1.7063747","volume":"143","author":"JA Hanley","year":"1982","unstructured":"Hanley JA, McNeil BJ. The meaning and use of the area under the receiver operating characteristic (ROC) curve. Radiology 1982;143:29\u201336.","journal-title":"Radiology"},{"key":"338786_CR14","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1161\/01.CIR.59.3.607","volume":"59","author":"World Health Organization.","year":"1979","unstructured":"World Health Organization. Report of the Joint International Society and Federation of Cardiology\/World Health Organization Task Force on Standardization of Clinical Nomenclature. Nomenclature and criteria for diagnosis of ischemic heart disease. Circulation 1979;59:607\u2013609.","journal-title":"Circulation"},{"key":"338786_CR15","doi-asserted-by":"crossref","first-page":"957","DOI":"10.7326\/0003-4819-110-12-957","volume":"110","author":"TH Lee","year":"1989","unstructured":"Lee TH, Weisberg MC, Brand DA, Rouan GW, Goldman L. Candidates for thrombolysis among emergency room patients with acute chest pain: potential true-and false-positive rates. Ann Intern Med 1989;110:957\u2013962.","journal-title":"Ann Intern Med"},{"key":"338786_CR16","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/S0002-9343(89)80603-5","volume":"87","author":"SR Weingarten","year":"1989","unstructured":"Weingarten SR, Ermann B, Riedinger MS, Shah PK, Ellrodt AG. Selecting the best triage rule for patients hospitalized with chest pain. Am J Med 1989;87:494\u2013500.","journal-title":"Am J Med"},{"key":"338786_CR17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1146\/annurev.med.45.1.31","volume":"45","author":"Y Rozenman","year":"1994","unstructured":"Rozenman Y, Gotsman MS. The earliest diagnosis of acute myocardial infarction. Ann Rev Med 1994;45:31\u201344.","journal-title":"Ann Rev Med"},{"key":"338786_CR18","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/S0735-1097(96)00392-0","volume":"28","author":"TJ Ryan","year":"1996","unstructured":"Ryan TJ, Anderson JL, Antman EM, et al. ACC\/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol 1996;28:1328\u20131428.","journal-title":"J Am Coll Cardiol"},{"key":"338786_CR19","unstructured":"The Cardiology Roundtable: Perfecting MI ruleout. Best practices for emergency evaluation of chest pain. Washington, DC: The Advisory Board Co., 1994:15."},{"key":"338786_CR20","first-page":"18","volume":"Suppl","author":"RH Christenson","year":"1997","unstructured":"Christenson RH, Newby LK, Ohman EM. Cardiac markers in the assessment of acute coronary syndromes. Md Med J 1997;Suppl:18\u201324.","journal-title":"Md Med J"},{"key":"338786_CR21","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/oxfordjournals.eurheartj.a062551","volume":"9","author":"HA Katus","year":"1998","unstructured":"Katus HA, Diederich KW, Scheffold T, Vellner M, Schwarz F, Kubler W. Non-invasive assessment of infarct reperfusion: the predictive power of the time to peak value of myoglobin, CKMB, and CK in serum. Eur Heart J 1998;9:619\u2013624.","journal-title":"Eur Heart J"},{"key":"338786_CR22","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/0002-9149(82)90459-3","volume":"50","author":"CW Pumphrey","year":"1982","unstructured":"Pumphrey CW, Dawes J. Plasma beta-thromboglobulin as a measure of platelet activity. Effect of risk factors and findings in ischemic heart disease and after acute myocardial infarction. Am J Cardiol 1982;50:1258\u20131261.","journal-title":"Am J Cardiol"},{"key":"338786_CR23","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1055\/s-0038-1657241","volume":"48","author":"A Hughes","year":"1982","unstructured":"Hughes A, Daunt S, Vass G, Wickes J. In vivo platelet activation following myocardial infarction and acute coronary ischemia. Thromb Haemost 1982;48:133\u2013135.","journal-title":"Thromb Haemost"},{"key":"338786_CR24","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1161\/01.CIR.92.7.1693","volume":"92","author":"H Ikeda","year":"1995","unstructured":"Ikeda H, Takajo Y, Ichiki K, et al. Increased soluble form of P-selectin in patients with unstable angina. Circulation 1995;92:1693\u20131696.","journal-title":"Circulation"},{"key":"338786_CR25","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00004872-199816010-00008","volume":"16","author":"MC Verhaar","year":"1998","unstructured":"Verhaar MC, Beutler JJ, Gaillard CA, Koomans HA, Fijnheer R, Rabelink TJ. Progressive vascular damage in hypertension is associated with increased levels of circulating P-selectin. J Hypertens 1998;16:45\u201350.","journal-title":"J Hypertens"},{"key":"338786_CR26","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1161\/01.CIR.92.7.1726","volume":"92","author":"K Kaikita","year":"1995","unstructured":"Kaikita K, Ogawa H, Yasue H, et al. Soluble P-selectin is released into the coronary circulation after coronary spasm. Circulation 1995;92:1726\u20131730.","journal-title":"Circulation"},{"key":"338786_CR27","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0049-3848(97)00263-6","volume":"88","author":"PA Gurbel","year":"1997","unstructured":"Gurbel PA, Serebruany VL. Myths and realities of plasma P-selectin levels in patients with acute myocardial infarction. Thromb Res 1997;88:343\u2013344.","journal-title":"Thromb Res"},{"key":"338786_CR28","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1161\/01.ATV.16.1.51","volume":"16","author":"EJ Langford","year":"1996","unstructured":"Langford EJ, Wainwright RJ, Martin JF. Platelet activation in acute myocardial infarction and unstable angina is inhibited by nitric oxide donors. Arterioscl Thromb Vasc Biol 1996;16:51\u201355.","journal-title":"Arterioscl Thromb Vasc Biol"},{"key":"338786_CR29","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/00019501-199404000-00010","volume":"5","author":"RC Becker","year":"1994","unstructured":"Becker RC, Tracy RP, Bovill EG, Mann KG, Ault K. The clinical use of flow cytometry for assessing platelet activation in acute coronary syndromes. TIMI-III Thrombosis and Anticoagulation Group. Cor Artery Dis 1994;5:339\u2013345.","journal-title":"Cor Artery Dis"},{"key":"338786_CR30","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/S0002-9149(96)00861-2","volume":"79","author":"N Tenaglia","year":"1997","unstructured":"Tenaglia N, Buda AJ, Wilkins RG, et al. Levels of expression of P-selectin, E-selectin, and intercellular adhesion molecule-1 in coronary atherectomy specimens from patients with stable and unstable angina pectoris. Am J Cardiol 1997;79:742\u2013747.","journal-title":"Am J Cardiol"},{"key":"338786_CR31","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1093\/clinchem\/44.8.1855","volume":"44","author":"RH Christenson","year":"1998","unstructured":"Christenson RH, Azzazy HM. Biochemical markers of the acute coronary syndromes. Clin Chem 1998;44:1855\u20131864.","journal-title":"Clin Chem"},{"key":"338786_CR32","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1161\/01.ATV.17.10.2044","volume":"17","author":"CJ Knight","year":"1997","unstructured":"Knight CJ, Panesar M, Wright C, et al. Altered platelet function detected by flow cytometry. Effects of coronary artery disease and age. Arterioscler Thromb Vasc Biol 1997;17:2044\u20132053.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"338786_CR33","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S0022-5223(97)70231-9","volume":"113","author":"DP Taggart","year":"1997","unstructured":"Taggart DP, Hadjinikolas L, Hooper JM, et al. Effects of age and ischemic times on biochemical evidence of myocardial injury after pediatric cardiac operations. J Thor Cardiovasc Surg 1997;113:728\u2013735.","journal-title":"J Thor Cardiovasc Surg"}],"container-title":["Journal of Thrombosis and Thrombolysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1011280801335.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1011280801335\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1011280801335.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T07:12:56Z","timestamp":1754637176000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1011280801335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,4]]}},"alternative-id":["338786"],"URL":"https:\/\/doi.org\/10.1023\/a:1011280801335","relation":{},"ISSN":["0929-5305","1573-742X"],"issn-type":[{"value":"0929-5305","type":"print"},{"value":"1573-742X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,4]]}}}