{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T04:03:27Z","timestamp":1748145807593,"version":"3.41.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biogerontology"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1023\/a:1011541302289","type":"journal-article","created":{"date-parts":[[2002,12,23]],"date-time":"2002-12-23T10:55:34Z","timestamp":1040640934000},"page":"105-108","source":"Crossref","is-referenced-by-count":7,"title":["Pinealectomy-associated decrease in ribosomal gene activity in rats"],"prefix":"10.1007","volume":"2","author":[{"given":"Spencer Luiz Marques","family":"Pay\u00e3o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina Valetta","family":"de Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson Roberto","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina Pekelmann","family":"Markus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucile Maria Floeter","family":"Winter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00edlia de Arruda Cardoso","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"321766_CR1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000213786","volume":"42","author":"B Borsatto","year":"1996","unstructured":"Borsatto B andSmith M de AC (1996) Reduction of the activity of ribosomal genes with age in Down's syndrome. Gerontology 42: 147\u2013154","journal-title":"Gerontology"},{"key":"321766_CR2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1056\/NEJM199701163360306","volume":"336","author":"A Brzezinski","year":"1997","unstructured":"Brzezinski A (1997) Melatonin in humans. N Engl J Med 336: 186\u2013195","journal-title":"N Engl J Med"},{"key":"321766_CR3","first-page":"199","volume":"25","author":"Committee for a Standardized Karyotype of Rattus norvergicus","year":"1973","unstructured":"Committee for a Standardized Karyotype of Rattus norvergicus (1973) Standard karyotype of the Norway rat, Rattus norvergiccus. Cytogenet Cell Genet 25: 199\u2013205","journal-title":"Cytogenet Cell Genet"},{"key":"321766_CR4","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1006\/excr.1998.4124","volume":"242","author":"MD Gray","year":"1998","unstructured":"Gray MD,Wang L,Youssoufian H,Martin GM andOshima J (1998) Werner helicase is localized to transcriptionally active nucleoli of cycling cells. Exp Cell Res 242: 487\u2013494","journal-title":"Exp Cell Res"},{"key":"321766_CR5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ar.1091530103","volume":"153","author":"RA Hoffman","year":"1965","unstructured":"Hoffman RA andReiter RJ (1965) Rapid pinealectomy in hamster and other small rodents. Anat Rec 153: 19\u201322","journal-title":"Anat Rec"},{"key":"321766_CR6","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1128\/MCB.15.4.2051","volume":"15","author":"G Houge","year":"1995","unstructured":"Houge G,Robaye B,Eikhom TS,Golstein J,Mellgren G,Gjertsen BT,Lanotte M andDoskeland SO (1995) Fine mapping of 28S rRNA sites specifically cleaved in cells undergoing apoptosis. Mol Cell Biol 15: 2051\u20132062","journal-title":"Mol Cell Biol"},{"key":"321766_CR7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3109\/10520298509113926","volume":"60","author":"HR Hubell","year":"1985","unstructured":"Hubell HR (1985) Silver staining as an indicator of active ribosomal genes. Stain Technol 60: 285","journal-title":"Stain Technol"},{"key":"321766_CR8","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1007\/BF01953855","volume":"36","author":"H Howell","year":"1980","unstructured":"Howell H andBlack DA (1980) Controlled silver-staining of nucleolar organizers regions with a protective collidal developer: A1-step method. Experientia 36: 1014\u20131015","journal-title":"Experientia"},{"key":"321766_CR9","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/hdy.1988.18","volume":"60","author":"R Jimenez","year":"1988","unstructured":"Jimenez R,Burgos M andde la Guardia RD (1988) A study of the Ag-staining significance in mitotic NORs. Heredity 60: 125\u2013127","journal-title":"Heredity"},{"key":"321766_CR10","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/240412a0","volume":"240","author":"R Johnson","year":"1972","unstructured":"Johnson R andStrehler BL (1972) Loss of genes coding for ribosomal RNA in ageing brain cells. Nature 240: 412\u2013414","journal-title":"Nature"},{"key":"321766_CR11","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3109\/07435808109045744","volume":"8","author":"TS King","year":"1981","unstructured":"King TS,Richardson BA andReiter RJ (1981) Age-associated changes in pineal serotonin N-acetyltransferase activity and melatonin content in the male gerbil. Endocr Res Commun 8: 253\u2013282","journal-title":"Endocr Res Commun"},{"key":"321766_CR12","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1006\/geno.1999.5959","volume":"3","author":"S Kitao","year":"1999","unstructured":"Kitao S,Lindor NM,Shiratori M,Furuichi Y andShimamoto A (1999) Rothmund-Thompson syndrome responsible gene, RECQL4: genomic structure and products. Genomics 3: 268\u2013276","journal-title":"Genomics"},{"key":"321766_CR13","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0306-9877(95)90092-6","volume":"45","author":"CP Maurizi","year":"1995","unstructured":"Maurizi CP (1995) The mystery of Alzheimer's disease and its prevention by melatonin. Med Hypotheses 45: 339\u2013340","journal-title":"Med Hypotheses"},{"key":"321766_CR14","first-page":"490","volume":"29","author":"DA Miller","year":"1977","unstructured":"Miller DA,Tantravahi R,Dev VG andMiller OJ (1977) Frequency of satellite association of human chromosomes with amount of Ag-staining of the nucleolus organizer regions. Am J Hum Genet 29: 490\u2013502","journal-title":"Am J Hum Genet"},{"key":"321766_CR15","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000213569","volume":"40","author":"SLM Pay\u00e3o","year":"1994","unstructured":"Pay\u00e3o SLM,Smith M de AC,Kormann-Bortolotto MH andToniolo J (1994) Investigation of the nucleolar organizer regions in Alzheimer's disease. Gerontology 40: 13\u201317","journal-title":"Gerontology"},{"key":"321766_CR16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0047-6374(98)00095-5","volume":"105","author":"SLM Pay\u00e3o","year":"1998","unstructured":"Pay\u00e3o SLM,Smith M de AC,Winter LMF andBertolucci PHF (1998) Ribosomal RNA in Alzheimer's disease and ageing. Mech Ageing Dev 105: 265\u2013272","journal-title":"Mech Ageing Dev"},{"key":"321766_CR17","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1210\/edrv-12-2-151","volume":"12","author":"RJ Reiter","year":"1991","unstructured":"Reiter RJ (1991) Pineal melatonin: cell biology of its synthesis and of synthesis and of its physiological interactions. Endocr Rev 12: 151\u2013180","journal-title":"Endocr Rev"},{"key":"321766_CR18","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/bies.950140307","volume":"14","author":"RJ Reiter","year":"1992","unstructured":"Reiter RJ (1992) The aging pineal gland and its physiological consequences. BioEssays 14: 169\u2013175","journal-title":"BioEssays"},{"key":"321766_CR19","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0047-6374(99)00058-5","volume":"110","author":"RJ Reiter","year":"1999","unstructured":"Reiter RJ,Tan DX,Kim SJ,Manchester LC,Qi W,Garcia JJ,Cabrera JC,El-Sokkary G andRouvier-Garay V (1999) Augmentation of indices of oxidative damage in life melatonindeficient rats. Mech Aging Dev 110: 157\u2013173","journal-title":"Mech Aging Dev"},{"key":"321766_CR20","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1093\/hmg\/8.6.1125","volume":"6","author":"L Riou","year":"1999","unstructured":"Riou L,Zeng L,Chevallier LO,Stary A,Nikaido O,Taieb A,Weeda G,Mezzina M andSarasin A (1999) The relative expression of mutated XPB genes results in xeroderma pigmentosum\/ Cockaine's syndrome or trichothiodystrophy cellula phenotypes. Hum Mol Genet 6: 1125\u20131133","journal-title":"Hum Mol Genet"},{"key":"321766_CR21","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1159\/000132208","volume":"41","author":"M Sasaki","year":"1986","unstructured":"Sasaki M,Nishida C andKodama Y (1986) Characterization of silver-stained nucleolus organizer regions (Ag-NORs) in 16 inbred strains of the Norway rat, Rattus norvergicus. Cytogenet Cell Genet 41: 83\u201388","journal-title":"Cytogenet Cell Genet"},{"key":"321766_CR22","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/0006-8993(90)90214-V","volume":"528","author":"DJ Skene","year":"1990","unstructured":"Skene DJ,Vivien-Roels B,Sparks DL,Hunsaker JC,P\u00e9vet P,Ravid D andSwaab DF (1990) Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease. Brain Res 528: 170\u2013174","journal-title":"Brain Res"},{"key":"321766_CR23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1126\/science.273.5271.59","volume":"273","author":"RS Sohal","year":"1996","unstructured":"Sohal RS andWeindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273: 59\u201363","journal-title":"Science"},{"key":"321766_CR24","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0006-8993(91)91270-B","volume":"545","author":"K Stokkan","year":"1991","unstructured":"Stokkan K,Reiter RJ,Nonaka KO,Lerchl A,Yu BP (1991) Food restriction retards aging of the pineal gland. Brain Res 545: 66\u201372","journal-title":"Brain Res"},{"key":"321766_CR25","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0304-4165(99)00125-7","volume":"1472","author":"DX Tan","year":"1999","unstructured":"Tan DX,Manchester LC,Reiter RJ,Qi W,Zhang M,Weintraub ST,Cabrera J,Sainz RM,Mayo JC (1999) Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. Biochim Biophys Acta 1472: 206\u2013214","journal-title":"Biochim Biophys Acta"},{"key":"321766_CR26","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/B978-1-4832-3194-5.50009-8","volume-title":"Human Chromosomes Methodology","author":"JH Tjio","year":"1965","unstructured":"Tjio JH andWang J (1965) Direct chromosomes preparations of bone marrow cells. In: Yunes JJ (ed) Human Chromosomes Methodology, pp 51\u201356. New York Academic Press, New York"},{"key":"321766_CR27","first-page":"330","volume":"60","author":"CE Yu","year":"1997","unstructured":"Yu CE,Oshima J,Wijsman EM,Nakura J,Miki T,Piussan C,Matthews S,Fu H,Mulligan J,Martin GM, Schellenberg GD and the Werner's Syndrome Collaborative Group (1997) Mutations in the consensus helicase domains of theWerner syndrome gene. Am J Hum Genet 60: 330\u2013341","journal-title":"Am J Hum Genet"}],"container-title":["Biogerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1011541302289.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1011541302289\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1011541302289.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T07:47:27Z","timestamp":1748072847000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1011541302289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["321766"],"URL":"https:\/\/doi.org\/10.1023\/a:1011541302289","relation":{},"ISSN":["1389-5729","1573-6768"],"issn-type":[{"type":"print","value":"1389-5729"},{"type":"electronic","value":"1573-6768"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}