{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:19:20Z","timestamp":1774916360187,"version":"3.50.1"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1997,2,1]],"date-time":"1997-02-01T00:00:00Z","timestamp":854755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1997,2,1]],"date-time":"1997-02-01T00:00:00Z","timestamp":854755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharm Res"],"published-print":{"date-parts":[[1997,2]]},"DOI":"10.1023\/a:1012056928780","type":"journal-article","created":{"date-parts":[[2002,12,23]],"date-time":"2002-12-23T06:56:00Z","timestamp":1040626560000},"page":"208-212","source":"Crossref","is-referenced-by-count":5,"title":["The Equivalent Bronchodilator Effects of Salbutamol Formulated in Chlorofluorocarbon and Hydrofluoroalkane-134a Metered Dose Inhalers on the Histamine-Induced Pulmonary Response in Dogs"],"prefix":"10.1007","volume":"14","author":[{"given":"Mari","family":"Nogami-Itoh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuhisa","family":"Yakuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Hammerbeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard L.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiko","family":"Takeyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"304117_CR1","unstructured":"Montreal Protocol. Sept. 16, 1987, 26 ILM 1541 (1987)."},{"key":"304117_CR2","first-page":"A58","volume":"151","author":"E. R. Bleecker","year":"1995","unstructured":"E. R. Bleecker, N. M. Klinger, B. P. Ekholm, and D. G. Tinkelman. Am. J. Respir. Crit. Care Med.\n151:A58 (1995).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"304117_CR3","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1089\/jam.1995.8.Suppl_1.S-41","volume":"8","author":"M. Jenkins","year":"1995","unstructured":"M. Jenkins. J. Aerosol Med.\n8:541\u2013547 (1995).","journal-title":"J. Aerosol Med."},{"key":"304117_CR4","first-page":"A58","volume":"151","author":"R. Ruffin","year":"1995","unstructured":"R. Ruffin, C. Mitchell, P. Thompson, D. Harle, A. Cline, and B. P. Ekholm. Am. J. Respir. Crit. Care Med.\n151:A58 (1995).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"304117_CR5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/BF01861842","volume":"195","author":"H. Konzett","year":"1940","unstructured":"H. Konzett, and R. Rossler. Arch. Exp. Path. Pharmak.\n195:71\u201374 (1940).","journal-title":"Arch. Exp. Path. Pharmak."},{"key":"304117_CR6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1476-5381.1969.tb07975.x","volume":"35","author":"V. A. Cullum","year":"1969","unstructured":"V. A. Cullum, J. B. Farmer, D. Jack and G. P. Levy. Br. J. Pharmacol.\n35:141\u2013151 (1969).","journal-title":"Br. J. Pharmacol."},{"key":"304117_CR7","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S0022-3565(25)30963-8","volume":"202","author":"Y. Yabuuchi","year":"1977","unstructured":"Y. Yabuuchi, S. Yamashita, and S. Tei. J. Pharmacol. Exp. Ther.\n202:326\u2013336 (1977).","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"304117_CR8","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1139\/y92-080","volume":"70","author":"E. E. Daniel","year":"1992","unstructured":"E. E. Daniel, A. P. Abela, L. J. Janssen, and P. M. O'Byrne. Can. J. Physiol. Pharmacol.\n70:624\u2013634 (1992).","journal-title":"Can. J. Physiol. Pharmacol."}],"container-title":["Pharmaceutical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1012056928780.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1012056928780\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1012056928780.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T06:34:46Z","timestamp":1754030086000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1012056928780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,2]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,2]]}},"alternative-id":["304117"],"URL":"https:\/\/doi.org\/10.1023\/a:1012056928780","relation":{},"ISSN":["0724-8741","1573-904X"],"issn-type":[{"value":"0724-8741","type":"print"},{"value":"1573-904X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,2]]}}}