{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:25:24Z","timestamp":1761560724578,"version":"3.41.2"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2002,2,1]],"date-time":"2002-02-01T00:00:00Z","timestamp":1012521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2002,2,1]],"date-time":"2002-02-01T00:00:00Z","timestamp":1012521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2002,2]]},"DOI":"10.1023\/a:1013749501241","type":"journal-article","created":{"date-parts":[[2002,12,23]],"date-time":"2002-12-23T17:20:10Z","timestamp":1040664010000},"page":"265-273","source":"Crossref","is-referenced-by-count":15,"title":["Control of Nocturnal Gastric Acidity: A Role for Low Dose Bedtime Ranitidine to Supplement Daily Omeprazole"],"prefix":"10.1007","volume":"47","author":[{"given":"Malcolm","family":"Robinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Rodriguez-Stanley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur A.","family":"Ciociola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Filinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sattar","family":"Zubaidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Philip B.","family":"Miner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry D.","family":"Gardner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"367745_CR1","first-page":"1102","volume":"87","author":"JR Jamieson","year":"1992","unstructured":"Jamieson JR, Stein HJ, DeMeester TR, Bonavina L, Schwizer W, Hinder RA, Albertucci M: Ambulatory 24-H esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity, and reproducibility. Am J Gastroenterol 87:1102\u20131111, 1992","journal-title":"Am J Gastroenterol"},{"key":"367745_CR2","first-page":"1071","volume":"87","author":"EMM Quigley","year":"1992","unstructured":"Quigley EMM: 24-H pH monitoring for gastroesophageal re-flux disease: already standard but not yet gold? Am J Gastroenterol 87:1071\u20131075, 1992","journal-title":"Am J Gastroenterol"},{"issue":"suppl1","key":"367745_CR3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000200917","volume":"51","author":"NJV Bell","year":"1992","unstructured":"Bell NJV, Burget D, Howden CW, Wilkinson J, Hunt RH: Appropriate acid suppression for the management of gastroesophageal reflux disease. Digestion 51(suppl 1):59\u201367, 1992","journal-title":"Digestion"},{"issue":"suppl1","key":"367745_CR4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-2036.1995.tb00777.x","volume":"9","author":"RH Hunt","year":"1995","unstructured":"Hunt RH: The relationship between the control of pH and healing and symptom relief in gastro-oesophageal reflux disease. Aliment Pharmacol Ther 9(suppl 1):3\u20137, 1995","journal-title":"Aliment Pharmacol Ther"},{"key":"367745_CR5","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2165\/00003088-199631050-00005","volume":"31","author":"JG Hatlebakk","year":"1996","unstructured":"Hatlebakk JG, Berstad A: Pharmacokinetic optimisation in the treatment of gastro-oesophageal reflux disease. Clin Pharmacokinet 31:386\u2013406, 1996","journal-title":"Clin Pharmacokinet"},{"key":"367745_CR6","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1159\/000007521","volume":"59","author":"J Dent","year":"1998","unstructured":"Dent J: Gastro-oesophageal reflux disease. Digestion 59:433\u2013445, 1998","journal-title":"Digestion"},{"key":"367745_CR7","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/S0016-5085(98)70010-1","volume":"115","author":"PL Peghini","year":"1998","unstructured":"Peghini PL, Katz PO, Castell DO: Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: A controlled study in normal subjects. Gastroenterology 115:1335\u20131339, 1998","journal-title":"Gastroenterology"},{"key":"367745_CR8","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1572-0241.1998.221_a.x","volume":"93","author":"PL Peghini","year":"1998","unstructured":"Peghini PL, Katz PO, Bracy NA, Castell DO: Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors. Am J Gastroenterol 93:763\u2013767, 1998","journal-title":"Am J Gastroenterol"},{"key":"367745_CR9","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1046\/j.1365-2036.1998.00419.x","volume":"12","author":"PO Katz","year":"1998","unstructured":"Katz PO, Anderson C, Khoury R, Castell DO: Gastrooesophageal reflux associated with nocturnal gastric acid breakthrough on proton pump inhibitors. Aliment Pharmacol Ther 12:1231\u20131234, 1998","journal-title":"Aliment Pharmacol Ther"},{"key":"367745_CR10","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1046\/j.1365-2036.1998.00426.x","volume":"11","author":"JG Hatlebakk","year":"1998","unstructured":"Hatlebakk JG, Katz PO, Kuo B, Castell DO: Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40 mg daily. Aliment Pharmacol Ther 11:1235\u20131240, 1998","journal-title":"Aliment Pharmacol Ther"},{"key":"367745_CR11","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1046\/j.1365-2036.1999.00499.x","volume":"13","author":"RM Khoury","year":"1999","unstructured":"Khoury RM, Katz PO, Hammod R, Castell DO: Bedtime ranitidine does not eliminate the need for a second daily dose of omeprazole to suppress nocturnal gastric pH. Aliment Pharmacol Ther 13:675\u2013678, 1999","journal-title":"Aliment Pharmacol Ther"},{"key":"367745_CR12","doi-asserted-by":"crossref","first-page":"A15","DOI":"10.1016\/S0016-5085(00)82128-9","volume":"118","author":"DL Earnest","year":"2000","unstructured":"Earnest DL, Sacks FD, Decktor DL, Levy SJ: Heartburn\/stomach symptoms during chronic proton pump inhibitor therapy: Evidence for occasional symptom breakthrough. Gastroenterology 118:A15, 2000","journal-title":"Gastroenterology"},{"key":"367745_CR13","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0016-5085(19)34564-0","volume":"49","author":"EW Moore","year":"1965","unstructured":"Moore EW, Scarlata RW: The determination of gastric acidity by the glass electrode. Gastroenterology 49:178\u2013188, 1965","journal-title":"Gastroenterology"},{"key":"367745_CR14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0016-5085(70)80035-X","volume":"58","author":"GM Makhlouf","year":"1970","unstructured":"Makhlouf GM, Blum AL, Moore EW: Undissociated acidity of human gastric juice. Gastroenterology 58:345\u2013351, 1970","journal-title":"Gastroenterology"},{"key":"367745_CR15","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1046\/j.1365-2036.1997.00227.x","volume":"11","author":"CE Grimley","year":"1997","unstructured":"Grimley CE, Constantinides S, Snell CC, Mills JG, Nwokolo CU: Inhibition of intragastric acidity in healthy subjects dosed with ranitidine 75 mg: A comparative study with cimetidine and placebo. Aliment Pharmacol Ther 11:875\u2013879, 1997","journal-title":"Aliment Pharmacol Ther"},{"key":"367745_CR16","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1111\/j.1572-0241.2001.03790.x","volume":"96","author":"JD Gardner","year":"2001","unstructured":"Gardner JD, Rodriguez-Stanley S, Robinson M: Integrated acidity and the pathophysiology of GERD. Am J Gastroenterol 96:1363\u20131370, 2001","journal-title":"Am J Gastroenterol"},{"key":"367745_CR17","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/0016-5085(91)90062-P","volume":"101","author":"B Hirschowitz","year":"1991","unstructured":"Hirschowitz B: A critical analysis, with appropriate controls, of gastric acid and pepsin secretion in clinical esophagitis. Gastroenterology 101:1149\u20131158, 1991","journal-title":"Gastroenterology"},{"key":"367745_CR18","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1007\/BF02071389","volume":"41","author":"B Hirschowitz","year":"1996","unstructured":"Hirschowitz B: Gastric secretion of acid and pepsin in patients with esophageal stricture and appropriate controls. Dig Dis Sci 41:2115\u20132122, 1996","journal-title":"Dig Dis Sci"},{"key":"367745_CR19","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1007\/BF02088563","volume":"41","author":"B Hirschowitz","year":"1996","unstructured":"Hirschowitz B: Gastric acid and pepsin secretion in patients with Barrett's esophagus and appropriate controls. Dig Dis Sci 41:1384\u20131391, 1996","journal-title":"Dig Dis Sci"},{"key":"367745_CR20","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/0016-5085(90)90285-9","volume":"98","author":"MJ Collen","year":"1990","unstructured":"Collen MJ, Lewis JH, Benjamin SB: Gastric acid hypersecretion in gastroesophageal reflux disease. Gastroenterology 98:654\u2013661, 1990","journal-title":"Gastroenterology"},{"key":"367745_CR21","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1007\/BF01307581","volume":"37","author":"MJ Collen","year":"1992","unstructured":"Collen MJ, Johnson DA: Correlation between basal acid output and daily ranitidine dose required for therapy in Barrett's esophagus. Dig Dis Sci 37:570\u2013576, 1992","journal-title":"Dig Dis Sci"},{"key":"367745_CR22","doi-asserted-by":"crossref","first-page":"837","DOI":"10.3109\/00365528609011128","volume":"21","author":"K-E Johansson","year":"1986","unstructured":"Johansson K-E, Ask P, Boeryd B, Fransson S-G, Tibbling L: Oesophagitis, signs of reflux, and gastric acid secretion in patients with symptoms of gastro-oesophageal reflux disease. Scand J Gastroenterol 21:837\u2013847, 1986","journal-title":"Scand J Gastroenterol"},{"key":"367745_CR23","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1172\/JCI107226","volume":"52","author":"JS Fordtran","year":"1973","unstructured":"Fordtran JS, Walsh JH: Gastric acid secretion rate and buffer content of the stomach after eating. J Clin Invest 52:645\u2013657, 1973","journal-title":"J Clin Invest"},{"key":"367745_CR24","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/0016-5085(86)91106-6","volume":"90","author":"M Feldman","year":"1986","unstructured":"Feldman M, Richardson CT: Total 24-hour gastric acid secretion in patients with duodenal ulcer. Gastroenterology 90:540\u2013544, 1986","journal-title":"Gastroenterology"},{"key":"367745_CR25","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0016-5085(19)34435-X","volume":"51","author":"GM Makhlouf","year":"1966","unstructured":"Makhlouf GM, McManus JPA, Card WI: A quantitative statement of the two-component hypothesis of gastric secretion. Gastroenterology 51:149\u2013171, 1966","journal-title":"Gastroenterology"},{"key":"367745_CR26","first-page":"595","volume-title":"Physiology of the Gastrointestinal Tract","author":"J Christensen","year":"1987","unstructured":"Christensen J: Motor functions of the pharynx and esophagus. Physiology of the Gastrointestinal Tract, Johnson LR, (ed), Vol 1, second ed. New York, Raven Press, 1987, pp 595\u2013612","edition":"second ed."}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1013749501241.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1013749501241\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1013749501241.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T03:44:37Z","timestamp":1753760677000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1013749501241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,2]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,2]]}},"alternative-id":["367745"],"URL":"https:\/\/doi.org\/10.1023\/a:1013749501241","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"type":"print","value":"0163-2116"},{"type":"electronic","value":"1573-2568"}],"subject":[],"published":{"date-parts":[[2002,2]]}}}