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The aim of the present study was to examine the efficacy of a continuous subcutaneous glucose monitoring system (CGMS MiniMed), to determine the magnitude and significance of hypoglycaemia in GSD I and to evaluate the efficacy of its dietary treatment. Four children with GSD I were studied over a 72\u2010h period. Results indicated that the values recorded with continuous subcutaneous glucose monitoring were highly correlated with paired blood glucose values measured by glucometer. Significant periods of asymptomatic hypoglycaemia were noted, especially during night\u2010time. The study suggests that repeated continuous subcutaneous glucose monitoring may serve as a useful tool for the assessment of the long\u2010term management of GSD I patients.<\/jats:p>","DOI":"10.1023\/a:1013996325720","type":"journal-article","created":{"date-parts":[[2002,12,28]],"date-time":"2002-12-28T18:55:48Z","timestamp":1041101748000},"page":"863-869","source":"Crossref","is-referenced-by-count":42,"title":["Continuous glucose monitoring in children with glycogen storage disease type I"],"prefix":"10.1002","volume":"24","author":[{"given":"E.","family":"Hershkovitz","sequence":"first","affiliation":[{"name":"Pediatric Endocrine and Metabolic Unit Soroka Medical University Center  Beer Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Rachmel","sequence":"additional","affiliation":[{"name":"Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes Schneider Children's Medical Center of Israel  Petah\u2010Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Ben\u2010Zaken","sequence":"additional","affiliation":[{"name":"Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes Schneider Children's Medical Center of Israel  Petah\u2010Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Phillip","sequence":"additional","affiliation":[{"name":"Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes Schneider Children's Medical Center of Israel  Petah\u2010Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8227(99)00113-8"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.2.222"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198401193100306"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1006\/mgme.2000.3013"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)70326-3"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.74.6.546"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70091-8"},{"key":"e_1_2_1_9_1","first-page":"751","article-title":"The MiniMed continuous glucose monitoring system","volume":"12","author":"Mastrototaro J","year":"1999","journal-title":"J Pediatr Endocrinol Metab"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19971031)72:3<286::AID-AJMG6>3.0.CO;2-P"},{"key":"e_1_2_1_11_1","first-page":"E561","article-title":"Subcutaneous glucose predicts plasma glucose independent of insulin: implications for continuous monitoring","volume":"40","author":"Rebrin K","year":"1999","journal-title":"Am J Physiol"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70107-9"},{"key":"e_1_2_1_13_1","first-page":"A126","article-title":"Accurate determination of plasma glucose during hyper\u2010and hypoglycemia with a subcutaneous glucose sensor","volume":"49","author":"Steil M","year":"2000","journal-title":"Diabetes"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.19.1839"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/65.5.1507"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199908000-00008"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/52.6.1043"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/52.6.1051"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70103-1"}],"container-title":["Journal of Inherited Metabolic Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1023%2FA%3A1013996325720","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1023\/A%3A1013996325720","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T21:39:03Z","timestamp":1694813943000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1023\/A%3A1013996325720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1023\/A:1013996325720"],"URL":"https:\/\/doi.org\/10.1023\/a:1013996325720","archive":["Portico"],"relation":{},"ISSN":["0141-8955","1573-2665"],"issn-type":[{"value":"0141-8955","type":"print"},{"value":"1573-2665","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}