{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T10:55:22Z","timestamp":1768042522616,"version":"3.49.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2001,7]]},"DOI":"10.1023\/a:1017911211090","type":"journal-article","created":{"date-parts":[[2002,12,30]],"date-time":"2002-12-30T14:36:44Z","timestamp":1041259004000},"page":"45-54","source":"Crossref","is-referenced-by-count":134,"title":["The evaluation of human breast lesions with magnetic resonance imaging and proton magnetic resonance spectroscopy"],"prefix":"10.1007","volume":"68","author":[{"given":"Kim M.","family":"Cecil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell D.","family":"Schnall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan S.","family":"Siegelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"Lenkinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"353810_CR1","first-page":"147","volume":"354A","author":"ME Lippman","year":"1990","unstructured":"Lippman ME, Dickson RB: Growth control of normal and malignant breast epithelium. Prog Clin Biol Res 354A: 147-178, 1990","journal-title":"Prog Clin Biol Res"},{"key":"353810_CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF00683189","volume":"27","author":"RJ King","year":"1993","unstructured":"King RJ: William L. McGuire Memorial Symposium. Estrogen and progestin effects in human breast carcinogenesis. Breast Cancer Res Treat 27: 3-15, 1993","journal-title":"Breast Cancer Res Treat"},{"key":"353810_CR3","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/0006-291X(89)92413-3","volume":"159","author":"Y Berthois","year":"1989","unstructured":"Berthois Y, Dong XF, Martin PM: Regulation of epidermal growth factor-receptor by estrogen and antiestrogen in the human breast cancer cell line MCF-7. Biochem Biophys Res Commun 159: 126-131, 1989","journal-title":"Biochem Biophys Res Commun"},{"key":"353810_CR4","doi-asserted-by":"crossref","first-page":"21172","DOI":"10.1016\/S0021-9258(17)45342-7","volume":"265","author":"AJ Stewart","year":"1990","unstructured":"Stewart AJ, Johnson MD, May FE, Westley BR: Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells. J Biol Chem 265: 21172-21178, 1990","journal-title":"J Biol Chem"},{"key":"353810_CR5","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1210\/mend-2-6-543","volume":"2","author":"SE Bates","year":"1988","unstructured":"Bates SE, Davidson NE, Valverius EM, Freter CE, Dickson RB, Tam JP, Kudlow JE, Lippman ME, Salomon DS: Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance. Mol Endocrinol 2: 543-555, 1988","journal-title":"Mol Endocrinol"},{"key":"353810_CR6","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1210\/endo.137.5.8612509","volume":"137","author":"DM Ignar-Trowbridge","year":"1996","unstructured":"Ignar-Trowbridge DM, Pimentel M, Parker MG, McLachlan JA, Korach KS: Peptide growth factor cross-talk with the estrogen receptor requires the A\/B domain and occurs independently of protein kinase C or estradiol. Endocrinology 137: 1735-1744, 1996","journal-title":"Endocrinology"},{"key":"353810_CR7","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1002\/j.1460-2075.1996.tb00571.x","volume":"15","author":"G Bunone","year":"1996","unstructured":"Bunone G, Briand PA, Miksicek RJ, Picard D: Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 15: 2174-2183, 1996","journal-title":"EMBO J"},{"key":"353810_CR8","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1095\/biolreprod58.3.627","volume":"58","author":"CL Smith","year":"1998","unstructured":"Smith CL: Cross-talk between peptide growth factor and estrogen receptor signalling pathways. Biol Reprod 58: 627-632, 1998","journal-title":"Biol Reprod"},{"key":"353810_CR9","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1126\/science.1749936","volume":"254","author":"RF Power","year":"1991","unstructured":"Power RF, Mani SK, Codina J, Conneely OM, O'Malley BW: Dopaminergic and ligand-independent activation of steroid hormone receptors. Science 254: 1636-1639, 1991","journal-title":"Science"},{"key":"353810_CR10","doi-asserted-by":"crossref","first-page":"8517","DOI":"10.1073\/pnas.91.18.8517","volume":"91","author":"SM Aronica","year":"1994","unstructured":"Aronica SM, Kraus WL, Katzenellenbogen BS: Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc Natl Acad Sci USA 91: 8517-8521, 1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"353810_CR11","doi-asserted-by":"crossref","first-page":"4658","DOI":"10.1073\/pnas.89.10.4658","volume":"89","author":"DM Ignar-Trowbridge","year":"1992","unstructured":"Ignar-Trowbridge DM, Nelson KG, Bidwell MC, Curtis SW, Washburn TF, McLachlan JA, Korach KS: Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor. Proc Natl Acad Sci USA 89: 4658-4662, 1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"353810_CR12","doi-asserted-by":"crossref","first-page":"12626","DOI":"10.1073\/pnas.93.22.12626","volume":"93","author":"SW Curtis","year":"1996","unstructured":"Curtis SW, Washburn T, Sewall C, DiAugustine R, Lindzey J, Couse JF, Korach KS: Physicological coupling of growth factor and steroid receptor signaling pathways: Estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor. Proc Natl Acad Sci USA 93: 12626-12630, 1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"353810_CR13","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1126\/science.270.5241.1491","volume":"270","author":"S Kato","year":"1995","unstructured":"Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H, Metzger D, Chambon P: Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270: 1491-1494, 1995","journal-title":"Science"},{"key":"353810_CR14","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1002\/j.1460-2075.1996.tb00471.x","volume":"15","author":"A Migliaccio","year":"1996","unstructured":"Migliaccio A, Di Domenico M, Castoria G, de Falco A, Bontempo P, Nola E, Auricchio F: Tyrosine kinase\/p21ras\/MAPkinase pathway activation by estradiol-receptor complex in MCF-7 cells. EMBO J 15: 1292-1300, 1996","journal-title":"EMBO J"},{"key":"353810_CR15","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1093\/emboj\/17.7.2008","volume":"17","author":"A Migliaccio","year":"1998","unstructured":"Migliaccio A, Piccolo D, Castori G, Di Domenico M, Bilanci A, Lombardi M, Gong WR, Beato M, Auricchio F: Activation of the Src\/p21(ras)\/Erk pathway by progesterone receptor via cross-talk with estrogen receptor. EMBO J 17: 2008-2018, 1998","journal-title":"EMBO J"},{"key":"353810_CR16","doi-asserted-by":"crossref","first-page":"4686","DOI":"10.1073\/pnas.96.8.4686","volume":"96","author":"T Improta-Brears","year":"1999","unstructured":"Improta-Brears T, Whorton AR, Codazzi F, York JD, Meyer T, McDonnell DP: Estrogen-induced activation of mitogenactivated protein kinase requires mobilization of intracellular calcium. Proc Natl Acad Sci USA 96: 4686-4691, 1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"353810_CR17","first-page":"5748","volume":"47","author":"OW Petersen","year":"1987","unstructured":"Petersen OW, Hoyer PE, Van Deurs B: Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. Cancer Res 47: 5748-5751, 1987","journal-title":"Cancer Res"},{"key":"353810_CR18","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF00689713","volume":"34","author":"A Molino","year":"1995","unstructured":"Molino A, Micciolo R, Turazza M, Bonetti F, Piubello Q, Corgnati A, Sperotto L, Martignoni G, Bonetti A, Nortilli R, Castelli P, Rodella S, Capelli P, Manfrin E, Pelosi G, Cetto GL: Estrogen receptors in 699 primary breast cancers: a comparison of immunohistochemical and biochemical methods. Breast Cancer Res Treat 34: 221-228, 1995","journal-title":"Breast Cancer Res Treat"},{"key":"353810_CR19","first-page":"6126","volume":"47","author":"SM Thorpe","year":"1987","unstructured":"Thorpe SM, Rose C, Rasmussen BB, Mouridsen HT, Bayer T, Keiding N: Prognostic value of steroid hormone receptors: multivariate analysis of systemically untreated patients with node negative primary breast cancer. Cancer Res 47: 6126-6133, 1987","journal-title":"Cancer Res"},{"key":"353810_CR20","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF02623578","volume":"23","author":"P Briand","year":"1987","unstructured":"Briand P, Petersen OW, Van Deurs B: A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium. In Vitro Cell Dev Biol 23: 181-188, 1987","journal-title":"Vitro Cell Dev Biol"},{"key":"353810_CR21","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0303-7207(96)03793-8","volume":"119","author":"BK Lundholt","year":"1996","unstructured":"Lundholt BK, Madsen MW, Lykkesfeldt AE, Petersen OW, Briand P: Characterization of a nontumorigenic human breast epithelial cell line stably transfected with the human estro gen receptor (ER) cDNA. Mol Cell Endocrinol 119: 47-59, 1996","journal-title":"Mol Cell Endocrinol"},{"key":"353810_CR22","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/0753-3322(96)82677-1","volume":"49","author":"F May","year":"1995","unstructured":"May F, Westley B: Estrogen regulated messenger RNAs in human breast cancer cells. Biomed Pharmacother 49: 400-414, 1995","journal-title":"Biomed Pharmacother"},{"key":"353810_CR23","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0960-0760(94)90035-3","volume":"51","author":"AS Levenson","year":"1994","unstructured":"Levenson AS, Jordan VC: Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines. J Steroid Biochem Mol Biol 51: 229-239, 1994","journal-title":"J Steroid Biochem Mol Biol"},{"key":"353810_CR24","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/S0140-6736(85)91385-6","volume":"1","author":"JR Sainsbury","year":"1985","unstructured":"Sainsbury JR, Farndon JR, Sherbet GV, Harris AL: Epidermalgrowth-factor receptors and oestrogen receptors in human breast cancer. Lancet 1: 364-366, 1985","journal-title":"Lancet"},{"key":"353810_CR25","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1210\/mend-1-3-216","volume":"1","author":"NE Davidson","year":"1987","unstructured":"Davidson NE, Gelmann EP, Lippman ME, Dickson RB: Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. Mol Endocrinol 1: 216-223, 1987","journal-title":"Mol Endocrinol"},{"key":"353810_CR26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0303-7207(99)00099-4","volume":"153","author":"P Briand","year":"1999","unstructured":"Briand P, Lundholt BK, Skouv J, Lykkesfeldt AE: Growth response of breast epithelial cells to estrogen is influenced by EGF. Mol Cell Endocrinol 153: 1-9, 1999","journal-title":"Mol Cell Endocrinol"},{"key":"353810_CR27","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/jnci\/51.5.1409","volume":"51","author":"HD Soule","year":"1973","unstructured":"Soule HD, Vazguez J, Long A, Albert S, Brennan M: A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51: 1409-1416, 1973","journal-title":"J Natl Cancer Inst"},{"key":"353810_CR28","first-page":"85","volume":"6","author":"P Briand","year":"1986","unstructured":"Briand P, Lykkesfeldt AE: Long-term cultivation of a human breast cancer cell line, MCF-7, in a chemically defined medium. Effect of estradiol. Anticancer Res 6: 85-90, 1986","journal-title":"Anticancer Res"},{"key":"353810_CR29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1210\/mend-3-1-203","volume":"3","author":"EM Valverius","year":"1989","unstructured":"Valverius EM, Bates SE, Stampfer MR, Clark R, McCormick F, Salomon DS, Lippman ME, Dickson RB: Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells. Mol Endocrinol 3: 203-214, 1989","journal-title":"Mol Endocrinol"},{"key":"353810_CR30","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1126\/science.2992089","volume":"229","author":"CR King","year":"1985","unstructured":"King CR, Kraus MH, Aaronson SA: Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 229: 974-976, 1985","journal-title":"Science"},{"key":"353810_CR31","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/path.1711640306","volume":"164","author":"J Bartek","year":"1991","unstructured":"Bartek J, Vojtesek B, Staskova Z, Bartkova J, Kerekes Z, Rejthar A, Kovarik J: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J Pathol 164: 215-224, 1991","journal-title":"J Pathol"},{"key":"353810_CR32","first-page":"1210","volume":"52","author":"MW Madsen","year":"1992","unstructured":"Madsen MW, Lykkesfeldt AE, Laursen I, Nielsen KV, Briand P: Altered gene expression of c-myc, epidermal growth factor receptor, transforming growth factor-alpha, and c-erb-B2 in an immortalized human breast epithelial cell line, HMT-3522, is associated with decreased growth factor requirements. Cancer Res. 52: 1210-1217, 1992","journal-title":"Cancer Res"},{"key":"353810_CR33","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1210\/endo.137.7.8770893","volume":"137","author":"RI Yarden","year":"1996","unstructured":"Yarden RI, Lauber AH, El-Ashry D, Chrysogelos SA: Bimodal regulation of epidermal growth factor receptor by estrogen in breast cancer cells. Endocrinology 137: 2739-2747, 1996","journal-title":"Endocrinology"},{"key":"353810_CR34","first-page":"3947","volume":"50","author":"LD Read","year":"1990","unstructured":"Read LD, Keith D, Slamon DJ, Katzenellenbogen BS: Hormonal modulation of HER-2\/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines. Cancer Res 50: 3947-3951, 1990","journal-title":"Cancer Res"},{"key":"353810_CR35","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/0006-291X(90)90853-F","volume":"166","author":"SJ Decker","year":"1990","unstructured":"Decker SJ: Epidermal growth factor and transforming growth factor-alpha induce differential processing of the epidermal growth factor receptor. Biochem Biophys Res Commun 166: 615-621, 1990","journal-title":"Biochem Biophys Res Commun"},{"key":"353810_CR36","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0092-8674(90)90801-K","volume":"61","author":"A Ullrich","year":"1990","unstructured":"Ullrich A, Schlessinger J: Signal transduction by receptors with tyrosine kinase activity. Cell 61: 203-212, 1990","journal-title":"Cell"},{"key":"353810_CR37","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1093\/emboj\/16.7.1647","volume":"16","author":"D Graus-Porta","year":"1997","unstructured":"Graus-Porta D, Beerli RR, Daly JM, Hynes NE: ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16: 1647-1655, 1997","journal-title":"EMBO J"},{"key":"353810_CR38","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1002\/ijc.2910440604","volume":"44","author":"CR De Potter","year":"1989","unstructured":"De Potter CR, Quatacker J, Maertens G, Van Daele S, Pauwels C, Verhofstede C, Eechaute W, Roels H: The subcellular localization of the neu protein in human normal and neoplastic cells. Int J Cancer 44: 969-974, 1989","journal-title":"Int J Cancer"},{"key":"353810_CR39","first-page":"7193","volume":"48","author":"C Malet","year":"1988","unstructured":"Malet C, Gompel A, Spritzer P, Bricout N, Yaneva H, Mowszowicz I, Kuttenn F, Mauvais-Jarvis P: Tamoxifen and hydroxytamoxifen isomers versus estradiol effects on normal human breast cells in culture. Cancer Res 48: 7193-7199, 1988","journal-title":"Cancer Res"},{"key":"353810_CR40","first-page":"5733","volume":"44","author":"M Chambon","year":"1984","unstructured":"Chambon M, Cavalie-Barthez G, Veith F, Vignon F, Hallowes R, Rochefort H: Effect of estradiol on nonmalignant human mammary cells in primary culture. Cancer Res 44: 5733-5743, 1984","journal-title":"Cancer Res"},{"key":"353810_CR41","first-page":"1263","volume":"5","author":"DL Miller","year":"1994","unstructured":"Miller DL, El-Ashry D, Cheville AL, Liu Y, McLeskey SW, Kern FG: Emergence of MCF-7 cells overexpressing a transfected epidermal growth factor receptor (EGFR) under estrogen-depleted conditions: evidence for a role of EGFR in breast cancer growth and progression. Cell Growth Differ 5: 1263-1274, 1994","journal-title":"Cell Growth Differ"},{"key":"353810_CR42","first-page":"5082","volume":"52","author":"T van Agthoven","year":"1992","unstructured":"van Agthoven T, van Agthoven TL, Portengen H, Foekens JA, Dorssers LC: Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells. Cancer Res 52: 5082-5088, 1992","journal-title":"Cancer Res"},{"key":"353810_CR43","first-page":"903","volume":"8","author":"A deFazio","year":"1997","unstructured":"deFazio A, Chiew YE, McEvoy M, Watts CKW, Sutherland RL: Antisense estrogen receptor RNA expression increases epidermal growth factor receptor gene expression in breast cancer cells. Cell Growth Differ 8: 903-911, 1997","journal-title":"Cell Growth Differ"},{"key":"353810_CR44","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1210\/mend-5-4-514","volume":"5","author":"RH Raja","year":"1991","unstructured":"Raja RH, Paterson AJ, Shin TH, Kudlow JE: Transcriptional regulation of the human transforming growth factor-alpha gene. Mol Endocrinol 5: 514-520, 1991","journal-title":"Mol Endocrinol"},{"key":"353810_CR45","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0960-0760(92)90183-J","volume":"43","author":"M De Bortoli","year":"1992","unstructured":"De Bortoli M, Dati C, Antoniotti S, Maggiora P, Sapei ML: Hormonal regulation of c-erbB-2 oncogene expression in breast cancer cells. J Steroid Biochem Mol Biol 43: 21-25, 1992","journal-title":"J Steroid Biochem Mol Biol"},{"key":"353810_CR46","first-page":"511","volume":"7","author":"ES Kornilova","year":"1992","unstructured":"Kornilova ES, Taverna D, Hoeck W, Hynes NE: Surface expression of erbB-2 prote in is post-transcriptionally regulated in mammary epithelial cells by epidermal growth factor and by the culture density. Oncogene 7: 511-519, 1992","journal-title":"Oncogene"},{"key":"353810_CR47","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1038\/bjc.1994.454","volume":"70","author":"S Antoniotti","year":"1994","unstructured":"Antoniotti S, Taverna D, Maggiora P, Sapei ML, Hynes NE, De Bortoli M: Oestrogen and epidermal growth factor downregulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms. Br J Cancer 70: 1095-1101, 1994","journal-title":"Br J Cancer"},{"key":"353810_CR48","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1006\/bbrc.1997.6746","volume":"235","author":"H Endoh","year":"1997","unstructured":"Endoh H, Sasaki H, Maruyama K, Takeyama K, Waga I, Shimizu T, Kato S, Kawashima H: Rapid activation of MAP kinase by estrogen in the bone cell line. Biochem Biophys Res Commun 235: 99-102, 1997","journal-title":"Biochem Biophys Res Commun"},{"key":"353810_CR49","first-page":"99","volume":"11","author":"EK Lobenhofer","year":"2000","unstructured":"Lobenhofer EK, Huper G, Iglehart JD, Marks JR: Inhibition of mitogen-activated prote in kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis. Cell Growth Differ 11: 99-110, 2000","journal-title":"Cell Growth Differ"},{"key":"353810_CR50","doi-asserted-by":"crossref","first-page":"11435","DOI":"10.1016\/S0021-9258(18)82142-1","volume":"268","author":"CF Zheng","year":"1993","unstructured":"Zheng CF, Guan KL: Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. J Biol Chem 268: 11435-11439, 1993","journal-title":"J Biol Chem"},{"key":"353810_CR51","doi-asserted-by":"crossref","first-page":"6808","DOI":"10.1073\/pnas.92.15.6808","volume":"92","author":"S Xu","year":"1995","unstructured":"Xu S, Robbins D, Frost J, Dang A, Lange-Carter C, Cobb MH: MEKK1 phosphorylates MEK1 andMEK 2 but does not cause activation of mitogen-activated protein kinase. Proc Natl Acad Sci USA 92: 6808-6812, 1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"353810_CR52","doi-asserted-by":"crossref","first-page":"13050","DOI":"10.1016\/S0021-9258(19)38617-X","volume":"268","author":"I Griswold-Prenner","year":"1993","unstructured":"Griswold-Prenner I, Carlin CR, Rosner MR: Mitogenactivated protein kinase regulates the epidermal growth factor receptor through activation of a tyrosine phosphatase. J Biol Chem 268: 13050-13054, 1993","journal-title":"J Biol Chem"},{"key":"353810_CR53","doi-asserted-by":"crossref","first-page":"24839","DOI":"10.1074\/jbc.273.38.24839","volume":"273","author":"H Keilhack","year":"1998","unstructured":"Keilhack H, Tenev T, Nyakatura E, Godovac-Zimmermann J, Nielsen L, Seedorf K, Bohmer FD: Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling. J Biol Chem 273: 24839-24846, 1998","journal-title":"J Biol Chem"},{"key":"353810_CR54","doi-asserted-by":"crossref","first-page":"5966","DOI":"10.1074\/jbc.272.9.5966","volume":"272","author":"T Tenev","year":"1997","unstructured":"Tenev T, Keilhack H, Tomic S, Stoyanov B, Stein-Gerlach M, Lammers R, Krivtsov AV, Ullrich A, Bohmer FD: Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptordirected activity to SHP-1\/SHP-2 chimera. J Biol Chem 272: 5966-5973, 1997","journal-title":"J Biol Chem"},{"key":"353810_CR55","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1096\/fasebj.9.5.7896011","volume":"9","author":"TC Pappas","year":"1995","unstructured":"Pappas TC, Gametchu B, Watson CS: Membrane estrogen receptors identified by multiple antibody labeling and impededligand binding. FASEB J 9: 404-410, 1995","journal-title":"FASEB J"},{"key":"353810_CR56","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/S1043-2760(99)00192-7","volume":"10","author":"ER Levin","year":"1999","unstructured":"Levin ER: Cellular functions of the plasma membrane estrogen receptor. Trends Endocrinol Metab 10: 374-377, 1999","journal-title":"Trends Endocrinol Metab"},{"key":"353810_CR57","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S1043-2760(99)00190-3","volume":"10","author":"MJ Kelly","year":"1999","unstructured":"Kelly MJ, Wagner EJ: Estrogen modulation of G-proteincoupled receptors. Trends Endocrinol Metab 10: 369-374, 1999","journal-title":"Trends Endocrinol Metab"},{"key":"353810_CR58","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/379557a0","volume":"379","author":"H Daub","year":"1996","unstructured":"Daub H, Weiss FU, Wallasch C, Ullrich A: Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379: 557-560, 1996","journal-title":"Nature"},{"key":"353810_CR59","first-page":"307","volume":"13","author":"M Razandi","year":"1999","unstructured":"Razandi M, Pedram A, Greene GL, Levin ER: Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ER alpha and ER beta expressed in Chinese hamster ovary cells. Mol Endocrinol 13: 307-319, 1999","journal-title":"Mol Endocrinol"},{"key":"353810_CR60","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1023\/A:1018718117113","volume":"3","author":"E Anderson","year":"1998","unstructured":"Anderson E, Clarke RB, Howell A: Estrogen responsiveness and control of normal human breast proliferation. J Mammary Gland Biol Neoplasia 3: 23-35, 1998","journal-title":"J Mammary Gland Biol Neoplasia"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1017911211090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1017911211090\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1023\/A:1017911211090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1017911211090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T04:16:45Z","timestamp":1750479405000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1017911211090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["353810"],"URL":"https:\/\/doi.org\/10.1023\/a:1017911211090","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,7]]}}}