{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:34:27Z","timestamp":1791221667940,"version":"4.1.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1997,5,1]],"date-time":"1997-05-01T00:00:00Z","timestamp":862444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1997,5,1]],"date-time":"1997-05-01T00:00:00Z","timestamp":862444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[1997,5]]},"DOI":"10.1023\/a:1018477809755","type":"journal-article","created":{"date-parts":[[2003,2,6]],"date-time":"2003-02-06T22:39:40Z","timestamp":1044571180000},"page":"524-528","source":"Crossref","is-referenced-by-count":19,"title":["Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring"],"prefix":"10.1007","volume":"8","author":[{"given":"Tomoko","family":"Fujii","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"171108_CR1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1080\/03610737608257179","volume":"2","author":"JC Martin","year":"1976","unstructured":"Martin JC, Martin DC, Radow B, Sigman G. Growth, development and activity in rat offspring following maternal drug exposure. Exper Aging Res 1976; 2: 235\u201351.","journal-title":"Exper Aging Res"},{"key":"171108_CR2","first-page":"238","volume-title":"Functional Teratogenesis: Func-tional Effects on the Offspring After Parental Drug Exposure","year":"1987","unstructured":"Fujii T, Adams PM, eds. Functional Teratogenesis: Func-tional Effects on the Offspring After Parental Drug Exposure. Tokyo, Japan: Teikyo University Press, 1987: 238."},{"key":"171108_CR3","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1254\/fpj.98.6_419","volume":"98","author":"T. Fujii","year":"1991","unstructured":"Fujii T. Integrative assessment of the developmental phar-macology and developmental toxicology, with special reference to the brain. Folia pharmacol japon1991; 98: 419\u201334.","journal-title":"Folia pharmacol japon"},{"key":"171108_CR4","first-page":"800","volume-title":"Toxicology from Discovery and Experimentation to the Hu-man Perspective","year":"1992","unstructured":"Chambers PL, Chambers CM, Bolt HM, Preziosi P, eds. Toxicology from Discovery and Experimentation to the Hu-man Perspective. Amsterdam, The Netherlands: Elsevier, 1992: 800."},{"key":"171108_CR5","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0140-6736(73)91291-9","volume":"i","author":"KL Jones","year":"1973","unstructured":"Jones KL, Smith DW, Ulleland CN, Streissguth AP. Pattern of malformation in offspring of chronic alcoholic mother. Lancet 1973; i: 1267\u201371.","journal-title":"Lancet"},{"key":"171108_CR6","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1126\/science.7350658","volume":"207","author":"C Kellogg","year":"1979","unstructured":"Kellogg C, Tervo D, Ison J, Parisi T, Miller RK. Prenatal exposure to diazepam alters behavioral development in rats. Science 1979; 207: 205\u20137.","journal-title":"Science"},{"key":"171108_CR7","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1126\/science.7200262","volume":"216","author":"C Gupta","year":"1982","unstructured":"Gupta C, Jaffe SJ, Shapiro BH. Prenatal exposure to phe-nobarbital permanently decreases testosterone and causes reproductive dysfunction. Science 1982; 216: 640\u20132.","journal-title":"Science"},{"key":"171108_CR8","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1159\/000457061","volume":"8","author":"T Fujii","year":"1985","unstructured":"Fujii T, Ohtaki Y. Sex-related hyperthermic response to chlorpromazine in the offspring of rats treated with imi-pramine. Dev Pharmacol Ther 1985; 8: 364\u201373.","journal-title":"Dev Pharmacol Ther"},{"key":"171108_CR9","first-page":"125","volume":"18","author":"MT Lin","year":"1979","unstructured":"Lin MT, Chern YF, Chow CF, Li YP. Effects of brain serotonin alterations on hypothermia produced by chlor-promazine in rats. Pharmacology 1979; 18: 125\u201335.","journal-title":"Pharmacology"},{"key":"171108_CR10","first-page":"677","volume":"7","author":"M Mirmiran","year":"1985","unstructured":"Mirmiran M, Brenner E, VanDerGugten J, Swaab DF. Neurochemical and electrophysiological disturbances mediate developmental behavioral alterations produced by medicines. Neurobehav Toxicol Teratol 1985; 7: 677\u201383.","journal-title":"Neurobehav Toxicol Teratol"},{"key":"171108_CR11","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0091-3057(90)90143-6","volume":"36","author":"H Nakanishi","year":"1990","unstructured":"Nakanishi H, Fujii T. Behavioral changes in juvenile rats after prenatal exposure to ethosuximide. Pharmacol Biochem Behav 1990; 36: 163\u20138.","journal-title":"Pharmacol Biochem Behav"},{"key":"171108_CR12","first-page":"187","volume-title":"Antiepileptic Drugs and Pregnancy","author":"Y Nomura","year":"1984","unstructured":"Nomura Y, Tak\u00e8re Y, Nomura Y, Shinagawa S, Kaneko S, Sato T. The physical and mental development of infants born to mothers treated with antiepileptic drugs. In: Sato S, Shinagawa S, eds. Antiepileptic Drugs and Pregnancy. Amsterdam, The Netherlands: Excerpta Medica, 1984: 187\u201395."},{"key":"171108_CR13","doi-asserted-by":"crossref","first-page":"140","DOI":"10.2183\/pjab.62.140","volume":"62B","author":"T Fujii","year":"1986","unstructured":"Fujii T, Hara N, Kuga Y. Maternal exposure of rats to sodium valproate develops tolerance to valproate itself in the offspring. Proc Japan Acad 1986; 62B: 140\u20133.","journal-title":"Proc Japan Acad"},{"key":"171108_CR14","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/0361-9230(83)90144-2","volume":"10","author":"JA Wallace","year":"1983","unstructured":"Wallace JA, Lauder JM. Development of serotonergic sys-tem in the rat embryo: An immunocytochemical study. Brain Res Bull 1983; 10: 459\u201379.","journal-title":"Brain Res Bull"},{"key":"171108_CR15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1471-4159.1973.tb04225.x","volume":"27","author":"JT Coyle","year":"1973","unstructured":"Coyle JT, Henry D. Catecholamines in fetal and newborn rat brain. J Neurochem 1973; 27: 61\u20137.","journal-title":"J Neurochem"},{"key":"171108_CR16","first-page":"125","volume-title":"Functional Neuroteratology of Short-termExposure to Drugs","author":"T Fujii","year":"1991","unstructured":"Fujii T, Kusama Y. Long-lasting effects on the brain of a single exposure to non-neuroactive compounds: Anticancer and immunosuppressive agents. In: Fujii T, Boer GJ, eds. Functional Neuroteratology of Short-termExposure to Drugs. Tokyo, Japan: Teikyo University Press, 1991: 125\u201339."},{"key":"171108_CR17","first-page":"411","volume-title":"Goodman and Gilman's The Pharmacological Basis of Therapeutics","year":"1996","unstructured":"Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th Ed. Hardman TG, Limbird LB, eds. New York, NY (USA): MacGraw-Hill, 1996: 411.","edition":"9th Ed."},{"key":"171108_CR18","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1469-8749.1980.tb04363.x","volume":"22","author":"RM. Rodier","year":"1980","unstructured":"Rodier RM. Chronology of neuron development: Animal studies and their clinical implications. Dev Med Child Neurol 1980; 22: 525\u201345.","journal-title":"Dev Med Child Neurol"},{"key":"171108_CR19","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/0277-5379(88)90302-1","volume":"24","author":"JM Kaldor","year":"1988","unstructured":"Kaldor JM, Day NE, Hemminki K. Quantifying the carcinogenicity of antineoplastic drugs. Eur J Cancer Clin Oncol 1988; 24: 703\u201311.","journal-title":"Eur J Cancer Clin Oncol"},{"key":"171108_CR20","first-page":"7","volume":"41","author":"T. Watanabe","year":"1990","unstructured":"Watanabe T. Chemicals and carcinogenicity. J Practical Pharmacy 1990; 41: 7\u201329.","journal-title":"J Practical Pharmacy"},{"key":"171108_CR21","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0278-6915(90)90108-Y","volume":"28","author":"E Ebert","year":"1990","unstructured":"Ebert E, Leist KH, Mayer D. Summary of safety evaluation toxicity studies of glufosinate ammonium. Fd Chem Toxic 1990; 28: 339\u201349.","journal-title":"Fd Chem Toxic"},{"key":"171108_CR22","first-page":"286","volume-title":"1994 Report of Comprehensive Research on the Human and Earth","author":"T. Fujii","year":"1994","unstructured":"Fujii T. Biochemical and pharmacological assessment of transgenerational and latent functional disorders induced by man-made toxic agents. 1994 Report of Comprehensive Research on the Human and Earth, in Aid of Ministry of Education, Science, Sports and Culture. Tokyo, Japan, 1994: 286\u20138."}],"container-title":["Cancer Causes & Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1018477809755.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1018477809755\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1018477809755.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T18:28:09Z","timestamp":1750962489000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1018477809755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,5]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,5]]}},"alternative-id":["171108"],"URL":"https:\/\/doi.org\/10.1023\/a:1018477809755","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,5]]}}}