{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:23:40Z","timestamp":1790421820094,"version":"4.1.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[1998,3]]},"DOI":"10.1023\/a:1018839930552","type":"journal-article","created":{"date-parts":[[2003,2,19]],"date-time":"2003-02-19T16:23:59Z","timestamp":1045671839000},"page":"652-662","source":"Crossref","is-referenced-by-count":17,"title":["In Vivo Alterations of Fluid and Electrolyte Fluxes in Rat Colon by Gamma Irradiation"],"prefix":"10.1007","volume":"43","author":[{"given":"Isabelle","family":"Dublineau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Ksas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyne","family":"Aigueperse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Gourmelon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina M.","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"294564_CR1","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1085\/jgp.43.3.555","volume":"43","author":"PF Curran","year":"1960","unstructured":"Curran PF, Schwartz GF: Na, Cl and water transport by rat colon. J Gen Physiol 43:555-571, 1960","journal-title":"J Gen Physiol"},{"key":"294564_CR2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1113\/jphysiol.1967.sp008380","volume":"193","author":"CJ Edmonds","year":"1967","unstructured":"Edmonds CJ: Transport of sodium and secretion of potassium and bicarbonate by the colon of normal and sodium-depleted rats. J Physiol 193:589-602, 1967","journal-title":"J Physiol"},{"key":"294564_CR3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0016-5085(69)80071-5","volume":"56","author":"GJ Devroede","year":"1969","unstructured":"Devroede GJ, Phillips SF: Conservation of sodium, chloride and water by the human colon. Gastroenterology 56:101-109, 1969","journal-title":"Gastroenterology"},{"key":"294564_CR4","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/978-3-642-77118-7_6","volume":"16","author":"VM Rajendran","year":"1993","unstructured":"Rajendran VM, Binder HJ: Ion transport in rat colon. Adv Comp Environ Physiol 16:113-137, 1993","journal-title":"Adv Comp Environ Physiol"},{"key":"294564_CR5","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1172\/JCI105781","volume":"47","author":"JS Fordtran","year":"1968","unstructured":"Fordtran JS, Rector FC, Carter NW: Theme chanisms of sodium absorption in the human small intestine. J Clin Invest 47:884-900, 1968","journal-title":"J Clin Invest"},{"key":"294564_CR6","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1113\/jphysiol.1993.sp019485","volume":"460","author":"KC Pedley","year":"1993","unstructured":"Pedley KC, Naftalin RJ: Evidence from fluore scence microscopy and comparative studies that rat, ovine and bovine colonic crypts are absorptive. J Physiol 460:525-547, 1993","journal-title":"J Physiol"},{"key":"294564_CR7","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1172\/JCI118294","volume":"96","author":"SK Singh","year":"1995","unstructured":"Singh SK, Binder HJ, Boron WF, Geibel JP: Fluid absorption in isolated perfused colonic crypts. J Clin Invest 96:2373-2379, 1995","journal-title":"J Clin Invest"},{"key":"294564_CR8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2307\/3570366","volume":"5","author":"RA Conard","year":"1956","unstructured":"Conard RA: Some effects of ionizing radiation on the physiology of the gastrointestinal tract: A review. Radiat Res 5:167- 188, 1956","journal-title":"Radiat Res"},{"key":"294564_CR9","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/0163-7258(88)90038-1","volume":"39","author":"P Geraci","year":"1988","unstructured":"Geraci P, Jackson KL, Mariano MS: Protection against the derangements associated with acute intestinal death. Pharmacol Ther 39:45-57, 1988","journal-title":"Pharmacol Ther"},{"key":"294564_CR10","first-page":"135","volume-title":"Military Radiobiology","author":"PJ Gunter-Smith","year":"1987","unstructured":"Gunter-Smith PJ: Effect of ionizing radiation on gastrointestinal physiology. InMilitary Radiobiology. JJ Conklin, PL Walker (eds). Orlando, Academic Press, 1987, pp 135-152"},{"key":"294564_CR11","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2307\/3570211","volume":"4","author":"H Quastler","year":"1956","unstructured":"Quastler H: The nature of intestinal radiation death. Radiat Res 4:303-320, 1956","journal-title":"Radiat Res"},{"key":"294564_CR12","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1080\/09553009014552281","volume":"58","author":"CS Potten","year":"1990","unstructured":"Potten CS: A comprehensive study of the radiobiological response of the murine (BDF1) intestine. Int J Radiat Biol 58:925-973, 1990","journal-title":"Int J Radiat Biol"},{"key":"294564_CR13","doi-asserted-by":"crossref","first-page":"G540","DOI":"10.1152\/ajpcell.1986.250.4.C540","volume":"250","author":"PJ Gunter-Smith","year":"1986","unstructured":"Gunter-Smith PJ: Gamma radiation affects active electrolyte transport by rabbit ileum: Basal Na and Cl transport. Am J Physiol 250:G540-G545, 1986","journal-title":"Am J Physiol"},{"key":"294564_CR14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.2307\/3577348","volume":"117","author":"PJ Gunter-Smith","year":"1989","unstructured":"Gunter-Smith PJ: Gamma radiation affects active electrolyte transport by rabbit ileum. II. Correlation of alanine and theophylline response with morphology. Radiat Res 117:419-432, 1989","journal-title":"Radiat Res"},{"key":"294564_CR15","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/0016-5085(94)90589-4","volume":"106","author":"WK MacNaughton","year":"1994","unstructured":"MacNaughton WK, Leach KE, Prud'homme-Lalonde L, Ho W, Sharkey KA: Ionizing radiation reduces neurally evoked electrolyte transport in rat ileum through a mast-cell-dependent mechanism. Gastroenterology 106:324-335, 1994","journal-title":"Gastroenterology"},{"key":"294564_CR16","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/0016-5085(78)90246-9","volume":"74","author":"JC Debongnie","year":"1978","unstructured":"Debongnie JC, Philipps SF: Capacity of the human colon to absorb fluid. Gastroenterology 74:698-703, 1978","journal-title":"Gastroenterology"},{"key":"294564_CR17","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1113\/jphysiol.1994.sp020214","volume":"477","author":"PS Zammit","year":"1994","unstructured":"Zammit PS, Mendizabal M, Naftalin RJ: Effects on fluid and Na+ flux of varying luminal hydraulic resistance in rat colon in vivo. J Physiol 477:539-548, 1994","journal-title":"J Physiol"},{"key":"294564_CR18","unstructured":"Lebrun F, Francois A, Vergnet M, Aigueperse J, Gourmelon P & Griffiths NM: (Abstract) Modification of rat intestinal muscarinic cholinergic receptors by ionizing radiation. Proceedings of the International Congress on Radiation Protection, Vienna, April, P24-21, 1996"},{"key":"294564_CR19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/B978-0-12-035412-2.50006-0","volume":"12","author":"A Becciolini","year":"1987","unstructured":"Becciolini A: Relative radiosensitivities of the small and large intestine. Adv Radiat Biol 12:83-128, 1987","journal-title":"Adv Radiat Biol"},{"key":"294564_CR20","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF02889015","volume":"32","author":"JP Sunter","year":"1979","unstructured":"Sunter JP, Watson AJ, Wright NA, Appleton DR: Cell proliferation at different sites along the length of the rat colon. Virchows Arch B Cell Pathol 32:75-87, 1979","journal-title":"Virchows Arch B Cell Pathol"},{"key":"294564_CR21","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1259\/0007-1285-44-524-599","volume":"44","author":"RF Hagemann","year":"1971","unstructured":"Hagemann RF, Lesher S: Irradiation of the G.I. tract: compensatory responses of stomach, jejunum and colon. Br J Radiol 44:599-602, 1971","journal-title":"Br J Radiol"},{"key":"294564_CR22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF01308173","volume":"37","author":"LR Empey","year":"1992","unstructured":"Empey LR, Papp JD, Jewell LD, Fedorak RN: Mucosal protective effects of vitamin E and misoprostol during acute radiation-induced enteritis in rats. Dig Dis Sci 37:205-214, 1992","journal-title":"Dig Dis Sci"},{"issue":"suppl","key":"294564_CR23","first-page":"A303","volume":"104","author":"WK MacNaughton","year":"1995","unstructured":"MacNaughton WK, Leach KE: Ionizing radiation-induced intestinal hypersecretion is region-specific and 5-HT3-dependent. Gastroenterology 104(suppl):A303, 1995","journal-title":"Gastroenterology"},{"key":"294564_CR24","first-page":"216","volume-title":"Gastrointestinal Radiation Injury","author":"MF Sullivan","year":"1966","unstructured":"Sullivan MF: Sodium, water and B12 absorption in irradiated rats: Influence of bile. InGastrointestinal Radiation Injury. MF Sullivan (ed). New York, Excerpta Medica, 1966, pp 216-226"},{"key":"294564_CR25","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.1016\/0024-3205(78)90197-2","volume":"23","author":"RI Walker","year":"1978","unstructured":"Walker RI, Porvaznik M: Association of leukopenia and intestinal permeability with radiation-induced sensitivity to endotoxin. Life Sci 23:2315-2322, 1978","journal-title":"Life Sci"},{"key":"294564_CR26","doi-asserted-by":"crossref","first-page":"233","DOI":"10.2307\/3575041","volume":"78","author":"M Porvaznik","year":"1979","unstructured":"Porvaznik M: Tight junction disruption and recovery after sublethal \u03b3 irradiation. Radiat Res 78:233-250, 1979","journal-title":"Radiat Res"},{"key":"294564_CR27","first-page":"3P","volume":"482P","author":"RJ Naftalin","year":"1995","unstructured":"Naftalin RJ, Pedley KC: The pericryptal fibroblast layer in rat descending colon sustains large transcryptal Na+ gradients. J Physiol 482P:3P, 1995","journal-title":"J Physiol"},{"key":"294564_CR28","doi-asserted-by":"crossref","first-page":"361","DOI":"10.2307\/3570474","volume":"8","author":"KL Jackson","year":"1958","unstructured":"Jackson KL, Rhodes R, Entenman C: Electrolyte excretion in the rat after severe intestinal damage by x-irradiation. Radiat Res 8:361-373, 1958","journal-title":"Radiat Res"},{"key":"294564_CR29","first-page":"683","volume":"69","author":"BT Jackson","year":"1976","unstructured":"Jackson BT: Bowel damage from radiation. Proc R Soc Med 69:683-686, 1976","journal-title":"Proc R Soc Med"},{"key":"294564_CR30","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1136\/gut.11.1.27","volume":"11","author":"J Harris","year":"1970","unstructured":"Harris J, Shields R: Absorption and secretion of water and electrolytes by the intact human colon in diffuse untreated proctocolitis. Gut 11:27-33, 1970","journal-title":"Gut"},{"key":"294564_CR31","unstructured":"Linard C, Esposito V, Aigueperse J, Gourmelon P: Influence of irradiation on gastrin releasing peptide. In10th International Congress of Radiation Research Congress Proceedings. U Hagen, H Jung, C Streffer (eds). 1995, P15-8"},{"key":"294564_CR32","doi-asserted-by":"crossref","first-page":"C848","DOI":"10.1152\/ajpcell.1996.270.3.C848","volume":"270","author":"TR Traynor","year":"1996","unstructured":"Traynor TR, O'Grady SM: Regulation of colonic ion transport by GRP. I GRP stimulates transepithelial K and Na secretion. Am J Physiol 270:C848-C858, 1996","journal-title":"Am J Physiol"},{"key":"294564_CR33","unstructured":"Fran\u00e7ois A, Aigueperse J, Gourmelon P, MacNaughton WK, Griffiths NM: Exposure to ionizing radiation modifies neurallyevoked electrolyte transport and some inflammatory responses in rat colon in vitro. Int J Radiat Biol (in press)."},{"key":"294564_CR34","doi-asserted-by":"publisher","first-page":"7460","DOI":"10.1074\/jbc.271.13.7460","volume":"271","author":"G Z\u00fcnd","year":"1996","unstructured":"Z\u00fcnd G, Madara JL, Dzus AL, Awtrey CS, Colgan SP: Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion. J Biol Chem 271:7460-7464, 1996","journal-title":"J Biol Chem"},{"key":"294564_CR35","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1007\/BF01296667","volume":"32","author":"RW Summers","year":"1987","unstructured":"Summers RW, Flatt AJ, Prihoda MJ, Mitros FA: Effect of irradiation on morphology and motility of canine small intestine. Dig Dis Sci 32:1402-1410, 1987","journal-title":"Dig Dis Sci"},{"key":"294564_CR36","first-page":"G518","volume":"263","author":"MF Otterson","year":"1992","unstructured":"Otterson MF, Sarna SK, Leming SC, Moulder JE, Fink JG: Effects of fractionated doses of ionizing radiation on colonic motor activity. Am J Physiol 263:G518-G526, 1992","journal-title":"Am J Physiol"},{"key":"294564_CR37","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1007\/BF02100119","volume":"41","author":"A Krantis","year":"1996","unstructured":"Krantis A, Rana K, Harding RK: The effects of \u03b3-radiation on intestinal motor activity and fecal pellet expulsion in the guinea pig. Dig Dis Sci 41:2307-2316, 1996","journal-title":"Dig Dis Sci"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1018839930552.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1018839930552\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1018839930552.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T02:53:18Z","timestamp":1752461598000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1018839930552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,3]]}},"alternative-id":["294564"],"URL":"https:\/\/doi.org\/10.1023\/a:1018839930552","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,3]]}}}