{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:51:12Z","timestamp":1761511872467,"version":"3.41.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1997,4,1]],"date-time":"1997-04-01T00:00:00Z","timestamp":859852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1997,4,1]],"date-time":"1997-04-01T00:00:00Z","timestamp":859852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Autism Dev Disord"],"published-print":{"date-parts":[[1997,4]]},"DOI":"10.1023\/a:1025839807431","type":"journal-article","created":{"date-parts":[[2003,10,24]],"date-time":"2003-10-24T19:29:37Z","timestamp":1067023777000},"page":"155-163","source":"Crossref","is-referenced-by-count":25,"title":["CSF \u03b2-Endorphin Levels in Patients with Infantile Autism"],"prefix":"10.1007","volume":"27","author":[{"given":"Shinichiro","family":"Nagamitsu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toyojiro","family":"Matsuishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiro","family":"Kisa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironori","family":"Komori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahito","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yushiro","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etsuo","family":"Ohtaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohisa","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"424523_CR1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0166-2236(85)90012-8","volume":"8","author":"Y. Agid","year":"1985","unstructured":"Agid, Y., & Javoy-Agid, F. (1985). Peptides and Parkinson's disease. Trends in Neurosciences, 8, 30\u201335.","journal-title":"Trends in Neurosciences"},{"key":"424523_CR2","first-page":"38","volume-title":"Diagnostic and statistical manual of mental disorder","author":"American Psychiatric Association.","year":"1987","unstructured":"American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorder (3rd ed., rev., pp. 38\u201339). Washington, DC: Author.","edition":"3rd ed., rev."},{"key":"424523_CR3","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1016\/0024-3205(86)90579-5","volume":"38","author":"T. Barreca","year":"1986","unstructured":"Barreca, T., Siani, C., Franceschini, R., Francaviglia, N., Messina, V, Perria, C, & Rolandia, E. (1986). Diurnal beta-endorphin changes in human cerebrospinal fluid. Life Sciences, 38, 2263\u20132267.","journal-title":"Life Sciences"},{"key":"424523_CR4","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/BF02172101","volume":"24","author":"S. L. Black","year":"1994","unstructured":"Black, S. L. (1994). Naltrexone in infantile autism. Journal of Autism and Developmental Disorders, 24, 236\u2013239.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"424523_CR5","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1126\/science.185694","volume":"194","author":"E. Bloom","year":"1976","unstructured":"Bloom, E., Segal, D., Ling, N., & Guillemin, R. (1976). Endorphins: profound behavioral effects in rats suggest new etiological factors in mental illness. Science, 194, 630\u2013632","journal-title":"Science"},{"key":"424523_CR6","first-page":"1024","volume":"1","author":"W. Domscher","year":"1979","unstructured":"Domscher, W., Dickschas, A., & Mitznegg, P. (1979). CSF \u03b2-endorphin in schizophrenia [Letter to editor]. Lancet, 1, 1024.","journal-title":"Lancet"},{"key":"424523_CR7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1177\/088307389100600310","volume":"6","author":"B. Echenne","year":"1991","unstructured":"Echenne, B., Bressot, N., Bassir, M., Daures, J. P., & Rabinowitz, A. (1991). Cerebrospinal fluid \u03b2-endorphin and cortisol study in Rett syndrome. Journal of Child Neurology, 6, 257\u2013262.","journal-title":"Journal of Child Neurology"},{"key":"424523_CR8","first-page":"221","volume":"29","author":"M. Ernst","year":"1993","unstructured":"Ernst, M., Devi, L., Silva, R. R., Gonzalez, N. M., Small, A. M., Malone, R. P., & Campbell, M. (1993). Plasma beta-endorphin levels, naltrexone, and haloperidol in autistic children. Psychopharmacology Bulletin, 29, 221\u2013227.","journal-title":"Psychopharmacology Bulletin"},{"key":"424523_CR9","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0387-7604(12)80185-9","volume":"12","author":"C. Gillberg","year":"1990","unstructured":"Gillberg, C., Terenius, L., Hagberg, B., Witt-Engerstr\u00f6m, I., & Eriksson, I. (1990). CSF beta-endorphins in childhood neuropsychiatric disorders. Brain and Development, 12 88\u201392.","journal-title":"Brain and Development"},{"key":"424523_CR10","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1001\/archpsyc.1985.01790310042005","volume":"42","author":"C. Gillberg","year":"1985","unstructured":"Gillberg, C., Terenius, L, & L\u00f6nnerholm, G. (1985). Endorphin activity in childhood psychosis. Archives of General Psychiatry, 42, 780\u2013783.","journal-title":"Archives of General Psychiatry"},{"key":"424523_CR11","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF01400529","volume":"91","author":"A. Gjerris","year":"1988","unstructured":"Gjerris, A., Gjerris, F., Sorensen, S. P., Sorensen, B. E., Christensen, J. N., Fahrenkrug, J., & Rehfeld, F. J. (1988). Do concentrations of neurotransmitters measured in lumbar cerebrospinal fluid reflect the concentrations at brain level? Acta Neurochirurgica (Wien), 91, 55\u201359.","journal-title":"Acta Neurochirurgica (Wien)"},{"key":"424523_CR12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0887-8994(89)90031-3","volume":"5","author":"B. A. Hagberg","year":"1989","unstructured":"Hagberg, B. A. (1989). Rett syndrome: Clinical peculiarities, diagnostic approach, and possible cause. Pediatric Neurology, 5, 75\u201383.","journal-title":"Pediatric Neurology"},{"key":"424523_CR13","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1001\/archpsyc.1977.01770170031002","volume":"34","author":"H. G. Hanley","year":"1977","unstructured":"Hanley, H. G., Stahl, S. M., & Freedman, D. X. (1977). Hyperserotonemia and amine metabolites in autistic and retarded children. Archives of General Psychiatry, 34, 44\u201348.","journal-title":"Archives of General Psychiatry"},{"key":"424523_CR14","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0166-2236(85)90048-7","volume":"8","author":"H. Khachaturian","year":"1985","unstructured":"Khachaturian, H., Lewis, M., Sch\u00e4fer, M., & Watson, S. (1985). Anatomy of the CNS opioid systems. Trends in Neurosciences, 8, 111\u2013119.","journal-title":"Trends in Neurosciences"},{"key":"424523_CR15","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1159\/000126258","volume":"56","author":"A. Kjaer","year":"1992","unstructured":"Kjaer, A., Knigge, U., Bach, F. W, & Warberg, J. (1992). Histamine and stress-induced secretion of ACTH and beta-endorphin: Involvement of corticotropin-releasing hormone and vasopressin. Neuroendocrinology, 56, 419\u2013428.","journal-title":"Neuroendocrinology"},{"key":"424523_CR16","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0140-6736(88)91525-5","volume":"1","author":"M. Leboyer","year":"1988","unstructured":"Leboyer, M., Bouvard, M. P., & Dugas, M. (1988). Effects of naltrexone on infantile autism. Lancet, 1, 715.","journal-title":"Lancet"},{"key":"424523_CR17","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/BF01058158","volume":"22","author":"M. Leboyer","year":"1992","unstructured":"Leboyer, M., Bouvard, M. P., Launay, J. M., Tabuteau, F., Waller, D., Dugas, M., Kerdelhue, B., Lensing, P., & Panksepp, J. (1992). Brief report: A double-blind study of naltrexone in infantile autism. Journal of Autism and Developmental Disorders, 22, 309\u2013319.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"424523_CR18","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/ana.410360317","volume":"35","author":"T Matsuishi","year":"1994","unstructured":"Matsuishi, T, Sakai, T, Nagamitsu, S., Komori, H., Iwashita, H., & Kato, H. (1994). Decreased cerebrospinal fluid levels of \u03b2-endorphin in Japanese patients with Joseph disease. Annals of Neurology, 35, 441\u2013443.","journal-title":"Annals of Neurology"},{"key":"424523_CR19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/oxfordjournals.bmb.a071795","volume":"39","author":"D. S. McQueen","year":"1983","unstructured":"McQueen, D. S. (1983). Opioid peptide interactions with respiratory and circulatory systems. British Medical Bulletin, 39, 77\u201382.","journal-title":"British Medical Bulletin"},{"key":"424523_CR20","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1212\/WNL.42.2.357","volume":"42","author":"C. E. Myer","year":"1992","unstructured":"Myer, C. E., Tripathi, L. H., Brase, A. D., & Dewey, L. W. (1992). Elevated CSF beta-endorphin immunoreactivity in Rett syndrome: Report of 158 cases and comparison with leukemic children. Neurology, 42, 357\u2013360.","journal-title":"Neurology"},{"key":"424523_CR21","doi-asserted-by":"crossref","first-page":"233","DOI":"10.2739\/kurumemedj.40.233","volume":"40","author":"S. Nagamitsu","year":"1993","unstructured":"Nagamitsu, S. (1993). CSF beta-endorphin levels in pediatric neurologic disorders. Kurume Medical Journal, 40, 233\u2013241.","journal-title":"Kurume Medical Journal"},{"key":"424523_CR22","volume-title":"Theory in psychopharmacology","author":"J. Panksepp","year":"1981","unstructured":"Panksepp, J. (1981). Brain opioids\u2014A neurochemical substrate for narcotic and social dependence. In S. J. Cooper (Ed.), Theory in psychopharmacology (Vol. 1). London: Academic Press."},{"key":"424523_CR23","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/978-1-4899-1992-2_19","volume-title":"Neurobiological issues in autism","author":"J. Panksepp","year":"1987","unstructured":"Panksepp, J., & Sahley, T. L. (1987). Possible brain opioid involvement in disrupted social intent and language development of autism. In E. Schopler & G. Mesibov (Eds.), Neurobiological issues in autism (pp. 357\u2013373). New York: Plenum Press."},{"key":"424523_CR24","volume-title":"The psychobiology of attachment","author":"J. Panksepp","year":"1985","unstructured":"Panksepp, J., Siviy, S. M., & Normansell, L. A. (1985). Brain opioids and social emotions. In M. Reite & T. Fields (Eds.), The psychobiology of attachment. New York: Academic Press."},{"key":"424523_CR25","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1177\/0883073888003001S12","volume":"3","author":"A. Percy","year":"1988","unstructured":"Percy, A., Zoghbi, H., Lewis, K., & Jankovic, J. (1988). Rett syndrome: Qualitative and quantitative differentiation from autism. Journal of Child Neurology, 3, 65\u201367.","journal-title":"Journal of Child Neurology"},{"key":"424523_CR26","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF01495056","volume":"17","author":"T. L. Sahley","year":"1987","unstructured":"Sahley, T. L., & Panksepp, J. (1987). Brain opioids and autism: An updated analysis of possible linkages. Journal of Autism and Developmental Disorders, 17, 201\u2013216.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"424523_CR27","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/BF02207000","volume":"21","author":"C. A. Sandman","year":"1991","unstructured":"Sandman, C. A., Barron, J. L., Chicz-DeMet, A., & Demet, E. M. (1991). Brief report: Plasma \u03b2-endorphin and cortisol levels in autistic patients. Journal of Autism and Developmental Disorders, 21, 83\u201387.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"424523_CR28","first-page":"1","volume-title":"Childhood developmental evaluation test for subjects 3 to 7 years old","author":"M. Tsumori","year":"1965","unstructured":"Tsumori, M., & Isobe, K. (1965). Childhood developmental evaluation test for subjects 3 to 7 years old (pp. 1\u2013218). Tokyo: Dai Nippon Tosho Corp."},{"key":"424523_CR29","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1055\/s-2008-1071393","volume":"11","author":"B. G. Winsberg","year":"1980","unstructured":"Winsberg, B. G., Sverd, J., Castell, S., Hurwic, M., & Perel, J. M. (1980). Estimation of monoamine and cyclic-AMP turnover and aminoacid concentrations of spinal fluid in autistic children. Neuropediatrics, 11, 250\u2013255.","journal-title":"Neuropediatrics"},{"key":"424523_CR30","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0167-0115(83)90009-5","volume":"6","author":"Y. Yamamoto","year":"1983","unstructured":"Yamamoto, Y., Yanaihara, C, Katsumaru, Y., Mochizuki, T., Tobe, A., Egawa, M., Imura, H., Numa, S., & Yanaihara, N. (1983). Synthesis of porcine leumorphin and some of its biological activity. Regulatory Peptides, 6, 163\u2013168.","journal-title":"Regulatory Peptides"}],"container-title":["Journal of Autism and Developmental Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1025839807431.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1025839807431\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1025839807431.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T11:39:43Z","timestamp":1748864383000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1025839807431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,4]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,4]]}},"alternative-id":["424523"],"URL":"https:\/\/doi.org\/10.1023\/a:1025839807431","relation":{},"ISSN":["0162-3257","1573-3432"],"issn-type":[{"type":"print","value":"0162-3257"},{"type":"electronic","value":"1573-3432"}],"subject":[],"published":{"date-parts":[[1997,4]]}}}