{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:59:57Z","timestamp":1791273597419,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[1999,2]]},"DOI":"10.1023\/a:1026654417697","type":"journal-article","created":{"date-parts":[[2003,11,6]],"date-time":"2003-11-06T12:29:30Z","timestamp":1068121770000},"page":"322-329","source":"Crossref","is-referenced-by-count":60,"title":["Glucagonlike Peptide-1 (GLP-1) Participation in Ileal Brake Induced by Intraluminal Peptones in Rat"],"prefix":"10.1007","volume":"44","author":[{"given":"Magda","family":"Giralt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patri","family":"Vergara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"295834_CR1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/BF01316798","volume":"38","author":"A Wettergren","year":"1993","unstructured":"Wettergren A, Schjoldager B, Mortensen PE, Myhre J, Christiansen J, Holst JJ: Truncated GLP-1 (proglucagon 78\u2013107\u2013amide) inhibits gastric and pancreatic functions in man. Dig Dis Sci 38:665\u2013673, 1993","journal-title":"Dig Dis Sci"},{"key":"295834_CR2","first-page":"84","volume":"109","author":"J Schirra","year":"1997","unstructured":"Schirra J, Kuwert P, Wank U, Leicht P, Arnold R, G\u00f6ke B, Katschinski M: Differential effects of subcutaneous GLP-1 on gastric emptying, antroduodenal motility, and pancreatic function in men. Proc Assoc Am Physicians 109:84\u201397, 1997","journal-title":"Proc Assoc Am Physicians"},{"key":"295834_CR3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0167-0115(98)00010-X","volume":"74","author":"M Giralt","year":"1998","unstructured":"Giralt M, Vergara P: Sympathetic pathways mediate GLP-1 actions in the gastrointestinal tract of the rat. Regul Pept 74:19\u201325, 1998","journal-title":"Regul Pept"},{"key":"295834_CR4","doi-asserted-by":"crossref","first-page":"3169","DOI":"10.1210\/endo-128-6-3169","volume":"128","author":"JN Roberge","year":"1991","unstructured":"Roberge JN, Brubaker PL: Secretion of proglucagon-derived peptides in response to intestinal luminal nutrients. Endocrinology 128:3169\u20133174, 1991","journal-title":"Endocrinology"},{"key":"295834_CR5","doi-asserted-by":"crossref","first-page":"892","DOI":"10.3109\/00365529509101597","volume":"30","author":"C Qualmann","year":"1995","unstructured":"Qualmann C, Nauck MA, Holst JJ, Orskov C, Cretzfeldt W: Glucagon-like peptide-1 (7\u201336 amide) secretion in response to luminal sucrose from the upper and lower gut. Scand J Gastroenterol 30:892\u2013896, 1995","journal-title":"Scand J Gastroenterol"},{"key":"295834_CR6","first-page":"G945","volume":"269","author":"J Wen","year":"1995","unstructured":"Wen J, Phillips SF, Sarr MG, Kost LJ, Holst JJ: PYY and GLP-1 contribute to feedback inhibition from the canine ileum and colon. Am J Physiol 269(Gastrointest Liver Physiol 32):G945\u2013G952, 1995","journal-title":"Am J Physiol"},{"key":"295834_CR7","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1210\/endo.135.6.7988423","volume":"135","author":"P Plaisancie","year":"1994","unstructured":"Plaisancie P, Bernard C, Chayvialle J-A, Cuber J-C: Regulation of glucagon-like peptide-1\u2013(7\u201336) amide secretion by intestinal neurotransmitters and hormones in the isolated vascularly perfused rat colon. Endocrinology 135:2398\u20132403, 1994","journal-title":"Endocrinology"},{"key":"295834_CR8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1365-2362.1992.tb01464.x","volume":"22","author":"R Eissele","year":"1992","unstructured":"Eissele R, G\u00f6ke R, Willemer S, Harthus H-P, Ve rmeer H, Arnold R, G\u00f6ke B: Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Invest 22:283\u2013291, 1992","journal-title":"Eur J Clin Invest"},{"key":"295834_CR9","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1007\/BF02064202","volume":"40","author":"P Layer","year":"1995","unstructured":"Layer P, Holst JJ, Grandt D, Goebell H: Ileal rele ase of glucagon-like peptide-1 (GLP-1). Association with inhibition of gastric acid secretion in humans. Dig Dis Sci 40:1074\u20131082, 1995","journal-title":"Dig Dis Sci"},{"key":"295834_CR10","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/BF01317060","volume":"29","author":"C Eeckhout","year":"1984","unstructured":"Eeckhout C, De Wever I, Vantrappen G: Intestinal motility after infusion of arachis oil into duodenum and ileum of dogs. Dig Dis Sci 29:164\u2013170, 1984","journal-title":"Dig Dis Sci"},{"key":"295834_CR11","first-page":"G671","volume":"254","author":"R Heddle","year":"1988","unstructured":"Heddle R, Dent J, Read NW, Houghton LA, Toouli J, Horowitz M, Maddern GJ, Downton J: Antropyloro-duodenal motor responses to intraduodenal lipid infusion in healthy volunteers. Am J Physiol 254(Gastrointest Liver Physiol 17):G671\u2013G679, 1988","journal-title":"Am J Physiol"},{"key":"295834_CR12","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/S0022-3565(25)12076-4","volume":"275","author":"A Rodr\u00edguez-Membrilla","year":"1995","unstructured":"Rodr\u00edguez-Membrilla A, Mart\u00ednez V, Vergara P: Peripheral and central CCK receptors regulate postprandial intestinal motility in the rat. J Pharmacol Exp Ther 275:486\u2013493, 1995","journal-title":"J Pharmacol Exp Ther"},{"key":"295834_CR13","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0031-6997(25)07049-8","volume":"16","author":"HW Kosterlitz","year":"1964","unstructured":"Kosterlitz HW, Lees GM: Pharmacological analysis of intrinsic intestinal reflexes. Pharmacol Rev 16:301\u2013339, 1964","journal-title":"Pharmacol Rev"},{"key":"295834_CR14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1113\/jphysiol.1975.sp010891","volume":"246","author":"CF Code","year":"1975","unstructured":"Code CF, Marlett JA: The interdigestive myoelectric complex of the stomach and small bowel of dogs. J Physiol London 246:289\u2013309, 1975","journal-title":"J Physiol London"},{"key":"295834_CR15","first-page":"377","volume":"54","author":"D D'Alessio","year":"1993","unstructured":"D'Alessio D, Thirlby R, Laschansky E, Zebroski H, Ensinck J: Response of tGLP-1 to nutrients in humans. Digestion 54:377\u2013379, 1993","journal-title":"Digestion"},{"key":"295834_CR16","first-page":"363","volume":"54","author":"PL Brubaker","year":"1993","unstructured":"Brubaker PL, Roberge JN: Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide through a novel enteroendocrine loop. Digestion 54:363\u2013365, 1993","journal-title":"Digestion"},{"key":"295834_CR17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1677\/joe.0.1380159","volume":"138","author":"RM Elliot","year":"1993","unstructured":"Elliot RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V: Glucagon-like peptide-1 (7\u201336)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: Acute post-prandial and 24\u2013h secretion patterns. J Endocrinol 138:159\u2013166, 1993","journal-title":"J Endocrinol"},{"key":"295834_CR18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000201118","volume":"55","author":"K Sugiyama","year":"1994","unstructured":"Sugiyama K, Manaka H, Kato T, Yamatani K, Tominaga M, Sasaki H: Stimulation of trucated glucagon-like peptide-1 release from isolated perfused canine ileum by glucose absorption. Digestion 55:24\u201328, 1994","journal-title":"Digestion"},{"key":"295834_CR19","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1113\/expphysiol.1983.sp002757","volume":"68","author":"O Keinke","year":"1983","unstructured":"Keinke O, Ehrlein HJ: Effect of oleic acid on canine gastroduodenal motility, pyloric diameter and gastric emptying. Q J Exp Physiol 68:675\u2013686, 1983","journal-title":"Q J Exp Physiol"},{"key":"295834_CR20","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/0016-5085(84)90411-6","volume":"86","author":"NW Read","year":"1984","unstructured":"Read NW, Mcfarlane A, Kinsman RI, Bates TE, Blackhall NW, Farrar GBJ, Hall JC, Moss G, Morris AP, O'Neill B, Welch I, Lee Y, Bloom SR: Effect of infusion of nutrient solutions into the ileum on gastrointestinal transit and plasma levels of neurotensin and enteroglucagon. Gastroenterology 86:274\u2013280, 1984","journal-title":"Gastroenterology"},{"key":"295834_CR21","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0016-5085(88)90428-3","volume":"94","author":"I Welch","year":"1988","unstructured":"Welch I, Cunningham KM, Read NW: Regulation of gastric emptying by ileal nutrients in humans. Gastroenterology 94:401\u2013404, 1988","journal-title":"Gastroenterology"},{"key":"295834_CR22","first-page":"G78","volume":"259","author":"ML Siegle","year":"1990","unstructured":"Siegle ML, Schmid HR, Ehrlein HJ: Effects of ileal infusions of nutrients on motor patterns of canine small intestine. Am J Physiol 259(Gastrointest Liver Physiol 22):G78\u2013G85, 1990","journal-title":"Am J Physiol"},{"key":"295834_CR23","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0016-5085(83)80079-1","volume":"85","author":"GM Fried","year":"1983","unstructured":"Fried GM, Ogden WD, Swerczek J, Greeley GH, Rayford PL, Thompson JC: Rele ase of cholecystokinin in conscious dogs: Correlation with simultaneous measurements of gallbladder pressure and pancreatic protein secretion. Gastroenterology 85:1113\u20131119, 1983","journal-title":"Gastroenterology"},{"key":"295834_CR24","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00006676-199701000-00012","volume":"14","author":"R Guimbaud","year":"1997","unstructured":"Guimbaud R, Moreau JA, Bouisson M, Durand S, Escourrou J, Vaysse N, Frexinos J: Intraduodenal free fatty acids rather than triglycerides are responsible for the release of CCK in humans. Pancreas 14:76\u201382, 1997","journal-title":"Pancreas"},{"key":"295834_CR25","first-page":"G243","volume":"251","author":"RA Liddle","year":"1986","unstructured":"Liddle RA, Green GM, Conrad CK, Williams JA: Proteins but not amino acids, carbohydrates, or fats stimulate cholecystokinin secretion in the rat. Am J Physiol 251(Gastrointest Liver Physiol 14):G243\u2013G248, 1986","journal-title":"Am J Physiol"},{"key":"295834_CR26","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/0016-5085(93)90890-O","volume":"105","author":"L Pironi","year":"1993","unstructured":"Pironi L, Stanghellini V, Miglioli M, Corinaldesi R, De Giorgio R, Ruggeri E, Tosetti C, Poggliolo G, Morselli Labate AM, Monetti N, Gozzetti G, Barbara L, Go VLW: Fat-induced ileal brake in humans: a dose-dependent phenomenon correlated to the plasma levels of peptide YY. Gastroenterology 105:733\u2013739, 1993","journal-title":"Gastroenterology"},{"key":"295834_CR27","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3109\/00365528509089699","volume":"20","author":"A Al-Saffar","year":"1985","unstructured":"Al-Saffar A, Hellstrom PM, Nylander G: Correlation between peptide YY-induced myoelectric activity and transit of small intestinal contents in rat. Scand J Gastroenterol 20:577\u2013582, 1985","journal-title":"Scand J Gastroenterol"},{"key":"295834_CR28","first-page":"487","volume":"31","author":"JC Brown","year":"1975","unstructured":"Brown JC, Dryburgh JR, Ross SA, Dupre J: Identification and actions of gastric inhibitory polypeptide. Recent Prog Horm Res 31:487\u2013532, 1975","journal-title":"Recent Prog Horm Res"},{"key":"295834_CR29","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1476-5381.1992.tb09050.x","volume":"105","author":"NJ Brown","year":"1992","unstructured":"Brown NJ, Rumsey RDE, Bogentoft C, Read NW: The effect of adrenoceptor antagonists on the ileal brake mechanism in the rat. Br J Pharmacol 105:751\u2013755, 1992","journal-title":"Br J Pharmacol"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1026654417697.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1026654417697\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1026654417697.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T03:15:16Z","timestamp":1752462916000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1026654417697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,2]]}},"alternative-id":["295834"],"URL":"https:\/\/doi.org\/10.1023\/a:1026654417697","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,2]]}}}