{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:34:18Z","timestamp":1761057258327,"version":"3.43.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1997,11,1]],"date-time":"1997-11-01T00:00:00Z","timestamp":878342400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1997,11,1]],"date-time":"1997-11-01T00:00:00Z","timestamp":878342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plant Mol Biol"],"published-print":{"date-parts":[[1997,11]]},"DOI":"10.1023\/a:1005884304303","type":"journal-article","created":{"date-parts":[[2002,12,21]],"date-time":"2002-12-21T18:56:21Z","timestamp":1040496981000},"page":"623-632","source":"Crossref","is-referenced-by-count":26,"title":["Heteromeric assembly of the cytosolic glutamine synthetase polypeptides of Medicago truncatula: complementation of a glnA Escherichia coli mutant with a plant domain-swapped enzyme"],"prefix":"10.1007","volume":"35","author":[{"given":"Helena","family":"Carvalho","sequence":"first","affiliation":[]},{"given":"Claudio","family":"Sunkel","sequence":"additional","affiliation":[]},{"given":"Roberto","family":"Salema","sequence":"additional","affiliation":[]},{"given":"Julie V.","family":"Cullimore","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"144517_CR1","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/323304a0","volume":"323","author":"RJ Almassy","year":"1986","unstructured":"Almassy RJ, Janson CA, Hamlin N, Xuong NH, Eisenberg D: Novel subunit-subunit interactions in the structure of glutamine synthetase. Nature 323: 304\u2013309 (1986).","journal-title":"Nature"},{"key":"144517_CR2","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/j.1432-1033.1994.00491.x","volume":"225","author":"C Appert","year":"1994","unstructured":"Appert C, Logemann E, Hahlbrock K, Schmid J, Amrhein N: Structural and catalytic properties of the four phenylalanine ammonia-lyase isoenzymes from parsley (Petroselinum crispum Nym.). Eur J Biochem 225: 491\u2013499 (1994).","journal-title":"Eur J Biochem"},{"key":"144517_CR3","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/BF00397582","volume":"179","author":"MJ Bennett","year":"1989","unstructured":"Bennett MJ, Cullimore JV: Glutamine synthetase isoenzymes of Phaseolus vulgaris L.: subunit composition in developing root nodules and plumules. Planta 179: 433\u2013440 (1989).","journal-title":"Planta"},{"key":"144517_CR4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1432-1033.1990.tb19340.x","volume":"193","author":"MJ Bennett","year":"1990","unstructured":"Bennett MJ, Culllmore JV: Expression of three plant glutamine synthetase cDNA in E. coli. Formation of catalytically active isoenzymes, and complementation of a glnA mutant. Eur J Biochem 193: 319\u2013324 (1990).","journal-title":"Eur J Biochem"},{"key":"144517_CR5","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1990","unstructured":"Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal Biochem 72: 248\u2013252 (1990).","journal-title":"Anal Biochem"},{"key":"144517_CR6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/BF00390175","volume":"150","author":"JV Cullimore","year":"1980","unstructured":"Cullimore JV, Sims AP: An association between photorespiration and protein catabolism: studies in Chlamydomonas. Planta 150: 392\u2013396 (1980).","journal-title":"Planta"},{"key":"144517_CR7","first-page":"155","volume":"31","author":"JV Cullimore","year":"1982","unstructured":"Cullimore JV, Lea PJ, Miflin BJ: Multiple forms of glutamine synthetase in the plant fraction of Phaseolus root nodules. Isr J Bot 31: 155\u2013162 (1982).","journal-title":"Isr J Bot"},{"key":"144517_CR8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF00405189","volume":"157","author":"JV Cullimore","year":"1983","unstructured":"Cullimore JV, Lara M, Lea PJ, Miflin BJ: Purification and properties of two forms of glutamine synthetase from the plant fraction of Phaseolus root nodules. Planta 157: 245\u2013253 (1983).","journal-title":"Planta"},{"key":"144517_CR9","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1126\/science.2871626","volume":"232","author":"S Dassarma","year":"1986","unstructured":"Dassarma S, Tischer E, Goodman HM: Plant glutamine synthetase complements a glnA mutation in E. coli. Science 232: 1242\u20131244 (1986).","journal-title":"Science"},{"key":"144517_CR10","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1094\/MPMI-1-066","volume":"1","author":"K Dunn","year":"1988","unstructured":"Dunn K, Dickstein R, Feinbaum R, Bumett BK, Peterman TK, Thoidis G, Goodman HM, Ausubel FM: Developmental regulation of nodule-specific genes in alfalfa root nodules. Mol Plant-Microbe Interact 1: 66\u201374 (1988).","journal-title":"Mol Plant-Microbe Interact"},{"key":"144517_CR11","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1101\/SQB.1987.052.01.055","volume":"52","author":"D Eisenberg","year":"1987","unstructured":"Eisenberg D, Almassy RJ, Janson CA, Chapman MS, Suh SW, Cascio D, Smith WW: Some evolutionary relationships of the primary biological catalysts glutamine synthetase and Rubisco. Cold Spring Harbor Symp Quant Biol 52: 483\u2013490 (1987).","journal-title":"Cold Spring Harbor Symp Quant Biol"},{"key":"144517_CR12","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1021\/bi00131a010","volume":"31","author":"MT Fischer","year":"1992","unstructured":"Fischer MT: Promotion of the in vitro renaturation of dodecameric glutamine synthetase from Escherichia coli in the presence of GroEL (Chaperonin-60) and ATP. Biochemistry 31: 3955\u20133963 (1992).","journal-title":"Biochemistry"},{"key":"144517_CR13","doi-asserted-by":"crossref","first-page":"13629","DOI":"10.1016\/S0021-9258(17)36876-X","volume":"269","author":"MT Fischer","year":"1994","unstructured":"Fischer MT: The effect of groES on the groEL-dependent assembly of dodecameric glutamine synthetase in the presence of ATP and ADP. J Biol Chem 269: 13629\u201313636 (1994).","journal-title":"J Biol Chem"},{"key":"144517_CR14","first-page":"247","volume":"6","author":"BG Forde","year":"1989","unstructured":"Forde BG, Cullimore JV: Glutamine synthetase in higher plants. Oxford Surv Plant Mol Cell Biol 6: 247\u2013296 (1989).","journal-title":"Oxford Surv Plant Mol Cell Biol"},{"key":"144517_CR15","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0168-9452(92)90001-4","volume":"82","author":"PD Green","year":"1992","unstructured":"Green PD, Wong PP: Subunit analysis of glutamine synthetase isoenzymes from root nodules of tepary bean (Phaseolus acutifolius Gray). Plant Sci 82: 179\u2013186 (1992).","journal-title":"Plant Sci"},{"key":"144517_CR16","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"UK Laemmli","year":"1970","unstructured":"Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680\u2013685 (1970).","journal-title":"Nature"},{"key":"144517_CR17","first-page":"121","volume-title":"The Biochemistry of Plants","author":"PJ Lea","year":"1990","unstructured":"Lea PJ, Robinson SA, Stewart GR: The enzymology and metabolism of glutamine, glutamate and asparagine. In: Miflin BJ, Lea PJ (eds) The Biochemistry of Plants, vol 16, pp. 121\u2013160. Academic Press, New York (1990)."},{"key":"144517_CR18","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1021\/bi00169a007","volume":"33","author":"SH Liaw","year":"1994","unstructured":"Liaw SH, Eisenberg D: Structural model for the reaction mechanism of glutamine synthetase, based on five crystal structures of enzyme-substrate complexes. Biochemistry 33: 675\u2013681 (1994).","journal-title":"Biochemistry"},{"key":"144517_CR19","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1002\/pro.5560041114","volume":"4","author":"SH Liaw","year":"1995","unstructured":"Liaw SH, Kuo I, Elsenberg D: Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site. Protein Sci 4: 2358\u20132365 (1995).","journal-title":"Protein Sci"},{"key":"144517_CR20","doi-asserted-by":"crossref","first-page":"5905","DOI":"10.1073\/pnas.92.13.5905","volume":"92","author":"E Logemann","year":"1995","unstructured":"Logemann E, Parniske M, Hahlbrock K: Modes of expression and common structural features of the complete phenylalanine ammonia-lyase gene family in parsley. Proc Natl Acad Sci USA 92: 5905-5909 (1995).","journal-title":"Proc Natl Acad Sci USA"},{"key":"144517_CR21","first-page":"1223","volume":"1","author":"TH Lubben","year":"1989","unstructured":"Lubben TH, Donaldson GK, Viitanen PV, Gatenby AA: Several proteins imported into chloroplasts form stable complexes with the GroEL related chloroplast molecular chaperone. Plant Cell 1: 1223\u20131230 (1989).","journal-title":"Plant Cell"},{"key":"144517_CR22","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/BF00015878","volume":"9","author":"V Lullien","year":"1987","unstructured":"Lullien V, Barker DG, de Lajudle P, Huguet T: Plant gene expression in effective and ineffective root nodules of alfalfa (Medicago sativa). Plant Mol Biol 9: 469\u2013478 (1987).","journal-title":"Plant Mol Biol"},{"key":"144517_CR23","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.1365-313X.1991.00999.x","volume":"1","author":"RB McGrath","year":"1991","unstructured":"McGrath RB, Coruzzi GM: A gene network controlling glutamine and asparagine biosynthesis in plants. Plant J 1: 275\u2013280 (1991).","journal-title":"Plant J"},{"key":"144517_CR24","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1128\/jb.146.1.260-268.1981","volume":"146","author":"D McNeil","year":"1981","unstructured":"McNeil D: General method, using Mu-Mud1 dilysogens, to determine the direction of transcription of the generate deletions in the glnA region of Escherichia coli. J Bact 146: 260\u2013268 (1981).","journal-title":"J Bact"},{"key":"144517_CR25","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF00290662","volume":"230","author":"TK Peterman","year":"1991","unstructured":"Peterman TK, Goodman HM: The glutamine synthetase gene family of Arabidopsis thaliana: light regulation and differential expression in leaves. roots and seeds. Mol Gen Genet 230: 145\u2013154 (1991).","journal-title":"Mol Gen Genet"},{"key":"144517_CR26","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1104\/pp.81.1.142","volume":"81","author":"FM Robert","year":"1986","unstructured":"Robert FM, Wong PP: Isozymes of glutamine synthetase in Phaseolus vulgaris L. and Phaseolus lunatus L. root nodules. Plant Physiol 81: 142\u2013148 (1986).","journal-title":"Plant Physiol"},{"key":"144517_CR27","volume-title":"Molecular Cloning: A Laboratory Manual","author":"J Sambrook","year":"1989","unstructured":"Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1989)."},{"key":"144517_CR28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1104\/pp.103.1.73","volume":"103","author":"C Stanford","year":"1993","unstructured":"Stanford C, Larsen K, Barker DG, Cullimore JV: Differential expression within the glutamine synthetase gene family of the model legume, Medicago truncatula. Plant Physiol 103: 73\u201381 (1993).","journal-title":"Plant Physiol"},{"key":"144517_CR29","first-page":"271","volume-title":"The Biochemistry of Plants","author":"GR Stewart","year":"1980","unstructured":"Stewart GR, Mann AF, Fentem PA: Enzymes of glutamate formation: glutamate dehydrogenase, glutamine synthetase and glutamate synthase. In: Miflin BJ (ed) The Biochemistry of Plants, vol 5, pp. 271\u2013327. Academic Press, New York, (1980)."},{"key":"144517_CR30","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1104\/pp.107.1.273","volume":"107","author":"U Szybiak-Strozycka","year":"1995","unstructured":"Szybiak-Strozycka U, Lescure N, Cullimore JV, Gamas P: A cDNA encoding a PR-1-like protein in the model legume Medicago truncatula. Plant Physiol 107: 273\u2013274 (1995).","journal-title":"Plant Physiol"},{"key":"144517_CR31","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF00277128","volume":"36","author":"SJ Temple","year":"1993","unstructured":"Temple SJ, Knight TJ, Unkefer PJ, Sengupta-Gopalan C: Modulation of glutamine synthetase gene expression in tobacco by the introduction of an alfalfa glutamine synthetase gene in sense and antisense orientation: molecular and biochemical analysis. Mol Gen Genet 36: 315\u2013325 (1993).","journal-title":"Mol Gen Genet"},{"key":"144517_CR32","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1094\/MPMI-8-0218","volume":"2","author":"SJ Temple","year":"1995","unstructured":"Temple SJ, Heard J, Ganter G, Dunn K, Sengupta-Gopalan C: Characterization of a nodule-enhanced glutamine synthetase from alfalfa: nucleotide sequence, in situ localization, and transcript analysis. Mol Plant-Microbe Interact 2: 218\u2013227 (1995).","journal-title":"Mol Plant-Microbe Interact"},{"key":"144517_CR33","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1104\/pp.112.4.1723","volume":"112","author":"SJ Temple","year":"1996","unstructured":"Temple SJ, Kunjibettu S, Roche D, Sengupta-Gopalan C: Total glutamine synthetase activity during soybean nodule development is controlled at the level of transcription and holoprotein turnover. Plant Physiol 112: 1723\u20131733 (1996).","journal-title":"Plant Physiol"},{"key":"144517_CR34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.1460-2075.1987.tb04710.x","volume":"6","author":"SV Tingey","year":"1987","unstructured":"Tingey SV, Walker EL, Coruzzi GM: Glutamine synthetase genes of pea encode distinct polypeptides which are differentially expressed in leaves, roots and nodules. EMBO J 6: 1\u20139 (1987).","journal-title":"EMBO J"},{"key":"144517_CR35","doi-asserted-by":"crossref","first-page":"9651","DOI":"10.1016\/S0021-9258(19)81566-1","volume":"263","author":"SV Tingey","year":"1988","unstructured":"Tingey SV, Tsai FY, Edwards JW, Walker EL, Coruzzi GM: Chloroplast and cytosolic glutamine synthetase are encoded by homologous nuclear genes which are differentially expressed in vivo. J Biol Chem 263: 9651\u20139657 (1988).","journal-title":"J Biol Chem"},{"key":"144517_CR36","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF00333958","volume":"203","author":"E Tischer","year":"1986","unstructured":"Tischer E, Dassarma S, Goodman HM: Nucleotide sequence of an alfalfa glutamine synthetase gene. Mol Gen Genet 203: 221\u2013229 (1986).","journal-title":"Mol Gen Genet"},{"key":"144517_CR37","doi-asserted-by":"crossref","unstructured":"Walker EL, Coruzzi GM: Developmental regulated expression of the gene family for the cytosolic glutamine synthetase in Pisum sativum. Plant Physiol: 702\u2013708 (1989).","DOI":"10.1104\/pp.91.2.702"}],"container-title":["Plant Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005884304303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1023\/A:1005884304303\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1023\/A:1005884304303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T04:54:18Z","timestamp":1754283258000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1023\/A:1005884304303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,11]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1997,11]]}},"alternative-id":["144517"],"URL":"https:\/\/doi.org\/10.1023\/a:1005884304303","relation":{},"ISSN":["0167-4412","1573-5028"],"issn-type":[{"type":"print","value":"0167-4412"},{"type":"electronic","value":"1573-5028"}],"subject":[],"published":{"date-parts":[[1997,11]]}}}