{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T11:40:47Z","timestamp":1652010047607},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2011,4,1]]},"abstract":"<jats:p> F\u00fcr viele chronische Lebererkrankungen und auch beim akuten Leberversagen ist eine Lebertransplantation die einzige kurative Therapie. In der Schweiz werden j\u00e4hrlich etwa 100 Lebertransplantationen durchgef\u00fchrt. Beim akuten Leberversagen gelten die Clichy-Kriterien f\u00fcr die Transplantationsindikation. Bei einer Leberzirrhose hat die Transplantation ab einem MELD-Score von 15 einen g\u00fcnstigen Effekt auf das Langzeit\u00fcberleben. Das 5- und 10-Jahres\u00fcberleben nach Lebertransplantation betr\u00e4gt 71% respektive 61%. Bei zunehmendem Langzeit\u00fcberleben wird das Management der Medikamentennebenwirkungen und kardiovaskul\u00e4ren Risiken immer wichtiger. <\/jats:p>","DOI":"10.1024\/0040-5930\/a000154","type":"journal-article","created":{"date-parts":[[2011,3,30]],"date-time":"2011-03-30T02:33:02Z","timestamp":1301452382000},"page":"219-224","source":"Crossref","is-referenced-by-count":0,"title":["Lebertransplantation"],"prefix":"10.1024","volume":"68","author":[{"given":"Pascal","family":"Frei","sequence":"first","affiliation":[{"name":"Swiss HPB (Hepato-Pancreato-Biliary) Center und Klinik f\u00fcr Gastroenterologie und Hepatologie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Geier","sequence":"additional","affiliation":[{"name":"Swiss HPB (Hepato-Pancreato-Biliary) Center und Klinik f\u00fcr Gastroenterologie und Hepatologie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Dutkowski","sequence":"additional","affiliation":[{"name":"Swiss HPB (Hepato-Pancreato-Biliary) Center und Klinik f\u00fcr Viszeral- und Transplantationschirurgie, Universit\u00e4tsSpital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beat","family":"M\u00fcllhaupt","sequence":"additional","affiliation":[{"name":"Swiss HPB (Hepato-Pancreato-Biliary) Center und Klinik f\u00fcr Gastroenterologie und Hepatologie"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a000154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:58:18Z","timestamp":1652007498000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a000154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4,1]]}},"alternative-id":["10.1024\/0040-5930\/a000154"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a000154","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,1]]}}}