{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T17:52:27Z","timestamp":1693504347399},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2014,9,1]]},"abstract":"<jats:p> Der wichtigste Vertreter der funktionellen Diarrhoe ist das Reizdarmsyndrom mit Diarrhoe, das charakterisiert ist durch chronisch intermittierende Diarrhoe und Bauchschmerzen. Pathophysiologisch wird eine Dysregulation der Interaktion zwischen enteralem und zentralem Nervensystem mit St\u00f6rung von motorischen, sensorischen und sekretorischen Funktionen postuliert sowie eine Assoziation mit genetischen und psychosozialen Faktoren. Die Therapie soll angepasst an die individuellen Beschwerden und den Leidensdruck erfolgen und umfasst allgemeine, medikament\u00f6se, di\u00e4tetische, psychotherapeutische und alternativ-komplement\u00e4re Ma\u00dfnahmen. <\/jats:p>","DOI":"10.1024\/0040-5930\/a000551","type":"journal-article","created":{"date-parts":[[2014,8,26]],"date-time":"2014-08-26T01:34:07Z","timestamp":1409016847000},"page":"551-558","source":"Crossref","is-referenced-by-count":2,"title":["Funktionelle Diarrhoe \u2013 Pathophysiologie, Abkl\u00e4rung und Therapie"],"prefix":"10.1024","volume":"71","author":[{"given":"Nora","family":"Schaub","sequence":"first","affiliation":[{"name":"Abteilung f\u00fcr Gastroenterologie und Hepatologie, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Degen","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Gastroenterologie und Hepatologie, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a000551","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T03:32:41Z","timestamp":1615951961000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a000551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9,1]]}},"alternative-id":["10.1024\/0040-5930\/a000551"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a000551","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,1]]}}}