{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:29:19Z","timestamp":1788398959925,"version":"build-2803163510"},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2015,2,1]]},"abstract":"<jats:p> Die Multiplex PCR Technologie h\u00e4lt in der mikrobiologischen Diagnostik mehr und mehr Einzug. Diese Technik erlaubt in einem einzigen Probenlauf die simultane Amplifikation von mehreren DNA\/RNA-Zielsequenzen von Erregern \u00fcber die Speziesebene hinaus. Verschiedene Erreger von Infektionskrankheiten k\u00f6nnen durch einen Symptom-orientierten Approach eindeutig und rasch mit hoher Zuverl\u00e4ssigkeit nachgewiesen werden. Im Wesentlichen verf\u00fcgt man heute \u00fcber Multiplex PCR-Panels zur Abkl\u00e4rung von gastrointestinalen, respiratorischen, urogenitalen Infekten, sowie zur Meningitis-Diagnostik. Das heutige Angebot der Industrie, der Universit\u00e4tsspit\u00e4ler und der gr\u00f6\u00dferen Privatlabors der Schweiz wird tabellarisch dargestellt und kommentiert. <\/jats:p>","DOI":"10.1024\/0040-5930\/a000647","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T02:09:41Z","timestamp":1422497381000},"page":"77-85","source":"Crossref","is-referenced-by-count":1,"title":["Verdr\u00e4ngt Multiplex PCR den klassischen Kulturnachweis in der Mikrobiologie?"],"prefix":"10.1024","volume":"72","author":[{"given":"Raymond","family":"Auckenthaler","sequence":"first","affiliation":[{"name":"synlab Suisse SA, Luzern"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Risch","sequence":"additional","affiliation":[{"name":"Kantonsspital Graub\u00fcnden, Chur und Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a000647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T07:39:15Z","timestamp":1615966755000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a000647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2,1]]}},"alternative-id":["10.1024\/0040-5930\/a000647"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a000647","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,1]]}}}