{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T01:23:45Z","timestamp":1649035425265},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p> Zusammenfassung. Die heterogene Gruppe der Nicht-Betalaktam-Antibiotika kann teilweise sehr schwere immunologisch vermittelte Hypersensitivit\u00e4tsreaktionen ausl\u00f6sen. Die Risiken daf\u00fcr sind unter den verschiedenen Vertretern sehr unterschiedlich verteilt und es ist teilweise eine genetische Pr\u00e4disposition zur Entwicklung von Stevens-Johnson-Syndrom \/ Toxisch epidermale Nekrolyse bzw. Drug rash with eosinophilia and systemic symptoms (DRESS-Syndrom) festzustellen. Einzelne Patientengruppen sind besonders h\u00e4ufig betroffen, u. a. Patienten mit HIV oder cystischer Fibrose. In dieser \u00dcbersicht werden die einzelnen Medikamentengruppen und entsprechende Risikosituationen, sowie die zur Verf\u00fcgung stehenden diagnostischen Mittel besprochen. <\/jats:p>","DOI":"10.1024\/0040-5930\/a001059","type":"journal-article","created":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T14:55:00Z","timestamp":1562597700000},"page":"13-21","source":"Crossref","is-referenced-by-count":0,"title":["Allergien gegen Nicht-Betalaktam-Antibiotika: eine Herausforderung in der                Praxis"],"prefix":"10.1024","volume":"76","author":[{"given":"Kathrin","family":"Scherer Hofmeier","sequence":"first","affiliation":[{"name":"Abteilung Allergologie, Klinik f\u00fcr Dermatologie,                Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a001059","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T22:39:15Z","timestamp":1615934355000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a001059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1024\/0040-5930\/a001059"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a001059","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}