{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T17:47:53Z","timestamp":1648576073097},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:p> Zusammenfassung. Die intrazerebrale Hirnblutung ist f\u00fcr ca. 10\u201315% aller Hirnschl\u00e4ge verantwortlich und betrifft in der Schweiz ca. 1\u2019500\u20132\u2019000 Patienten pro Jahr. Bei der Akutbehandlung ist eine interdisziplin\u00e4re Behandlung durch spezialisierte Experten in einer zertifizierten Stroke Unit oder einem Stroke Center von entscheidender Bedeutung. Ein simples ABC-care bundle (Antikoagulation revertieren, Blutdruck kontrollieren, Neurochirurgen informieren) kann das Outcome signifikant verbessern. Trotz einer hohen Mortalit\u00e4t sind ca. ein Drittel aller Patienten nach einer Hirnblutung funktionell unabh\u00e4ngig und der weitverbreitete Pessimismus ist unangebracht. \u00dcber 80% aller Hirnblutungen werden durch verschiedene Formen cerebraler Mikroangiopathien verursacht und die Risiken f\u00fcr eine erneute Hirnblutung oder einen isch\u00e4mischen Hirnschlag unterscheiden sich deutlich. Hirnblutungspatienten sind vaskul\u00e4re Hochrisikopatienten mit einer chronischen, cerebrovaskul\u00e4ren Erkrankung. Sie sollten langfristig und regelm\u00e4ssig von neurovaskul\u00e4ren Spezialisten behandelt werden, um wichtige Fragen (Blutdruckmanagement, antithrombotische Therapie\/Antikoagulation, spezialisierte Neurorehabilitation zur Verbesserung insbesondere neurokognitiver Defizite, Therapie zus\u00e4tzlicher Komplikationen, z.\u2009B. Epilepsie) individuell zu kl\u00e4ren und die optimale Behandlung f\u00fcr die Patienten zu gew\u00e4hrleisten. Viele aktuelle Studien werden in den n\u00e4chsten Jahren wichtige Ergebnisse liefern, um die Behandlung der Hirnblutung weiter zu verbessern. <\/jats:p>","DOI":"10.1024\/0040-5930\/a001276","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T09:19:43Z","timestamp":1626945583000},"page":"320-327","source":"Crossref","is-referenced-by-count":0,"title":["Die intrazerebrale Hirnblutung: Akutes Ereignis und chronische                Erkrankung"],"prefix":"10.1024","volume":"78","author":[{"given":"Martina","family":"G\u00f6ldlin","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Inselspital Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Radojewski","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle Neuroradiologie, Inselspital                Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Siepen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Inselspital Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madlaine","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Inselspital Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Wiest","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle Neuroradiologie, Inselspital                Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Mordasini","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle Neuroradiologie, Inselspital                Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandros","family":"Polymeris","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan T.","family":"Engelter","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Universit\u00e4tsspital Basel"},{"name":"Neurorehabilitation, Universit\u00e4re Altersmedizin Felix-Platter, Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Lyrer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Z\u2019Graggen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Inselspital Universit\u00e4tsspital Bern"},{"name":"Klinik f\u00fcr Neurochirurgie, Inselspital Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urs","family":"Fischer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Inselspital Universit\u00e4tsspital Bern"},{"name":"Klinik f\u00fcr Neurologie, Universit\u00e4tsspital Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Seiffge","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie, Inselspital Universit\u00e4tsspital Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a001276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T09:19:47Z","timestamp":1626945587000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a001276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1024\/0040-5930\/a001276"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a001276","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]}}}