{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T13:11:39Z","timestamp":1649164299678},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p> Zusammenfassung. Die menopausale \u00dcbergangszeit ist gekennzeichnet durch den Verlust der Eizellreserve, das heisst der Zahl und Qualit\u00e4t der Oozyten. Diese Beeintr\u00e4chtigung f\u00fchrt zu einer schnellen und massiven Abnahme der Fertilit\u00e4t. Die Eizellreserve l\u00e4sst sich mit der Messung von FSH und AMH im Serum bestimmen sowie mit der Z\u00e4hlung der ultrasonografisch sichtbaren Follikel, dem sogenannten \u00abantral follicle count\u00bb (AFC). Therapeutisch k\u00f6nnen zur Erf\u00fcllung des Kinderwunsches homologe Behandlungen wie monofollikul\u00e4re Hormonstimulationen und die In-Vitro-Fertilisation eingesetzt werden. Wesentlich aussichtsreicher ist jedoch meist die heterologe Eizellspendenbehandlung. Pr\u00e4ventiv wird zunehmend die Methode des \u00abSocial Egg Freezing\u00bb angewendet. <\/jats:p>","DOI":"10.1024\/0040-5930\/a001290","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T09:34:21Z","timestamp":1632476061000},"page":"407-411","source":"Crossref","is-referenced-by-count":0,"title":["Kinderwunsch in der menopausalen \u00dcbergangszeit"],"prefix":"10.1024","volume":"78","author":[{"given":"Bruno","family":"Imthurn","sequence":"first","affiliation":[{"name":"Medizinische Fakult\u00e4t Universit\u00e4t Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a001290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T09:34:22Z","timestamp":1632476062000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a001290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1024\/0040-5930\/a001290"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a001290","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}