{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T09:44:32Z","timestamp":1648979072998},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p> Zusammenfassung. Myelodysplastische\/myeloproliferative Neoplasien sind nicht selten diagnostische und therapeutische Herausforderungen. Da Entz\u00fcndungen geh\u00e4uft bei diesen St\u00f6rungen gesehen werden k\u00f6nnen und zu \u00e4hnlichen Blutbildver\u00e4nderungen f\u00fchren, kann eine gesicherte Diagnose nicht selten erst im Verlauf gestellt werden. Aus therapeutischer Sicht stehen sich das Bremsen der Proliferation und die Stimulation der Zytopenie bei Dysplasie kontr\u00e4r gegen\u00fcber. Hypomethylinisierende Substanzen sind daher eine typische Therapie bei diesen Krankheitsbildern. <\/jats:p>","DOI":"10.1024\/0040-5930\/a001335","type":"journal-article","created":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T07:57:14Z","timestamp":1647417434000},"page":"107-113","source":"Crossref","is-referenced-by-count":0,"title":["Wenn die Dysplasie und die Proliferation zusammen                kommen: MDS\/MPN"],"prefix":"10.1024","volume":"79","author":[{"given":"Rudolf","family":"Benz","sequence":"first","affiliation":[{"name":"Abteilung Onkologie\/H\u00e4matologie, Spital Thurgau,                M\u00fcnsterlingen\/Frauenfeld"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930\/a001335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T07:27:22Z","timestamp":1647502042000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930\/a001335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1024\/0040-5930\/a001335"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930\/a001335","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3]]}}}