{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:35:48Z","timestamp":1792146948718,"version":"4.4.0"},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[1999,9,1]]},"abstract":"<jats:p> Eine 26j\u00e4hrige Frau, nach notfallm\u00e4\u00dfiger Entbindung in der 33. Schwangerschaftswoche wegen eines HELLP (Hemolysis, Elevated Liver enzymes, Low Platelets)-Syndroms, entwickelte postpartal eine Poplitealvenenthrombose, Lungenembolien sowie eine Pfortaderthrombose. Nach Abschlu\u00df der peroralen Antikoagulation w\u00e4hrend sechs Monaten fanden sich in der Thrombophilie-Abkl\u00e4rung ein Plasminogen-Mangel, ein vermindertes freies Protein S sowie (retrospektiv) eine APC-Resistenz bei heterozygoter FV R506Q (FV Leiden)-Mutation. Nach einer beschwerdefreien Zeit von 6 Jahren stellte man bei der Patientin anl\u00e4\u00dflich einer sonographischen Abkl\u00e4rung wegen Bauchschmerzen neu eine Leberzirrhose und ein in der MRI-Untersuchung best\u00e4tigtes Budd-Chiari-Syndrom fest. Die erneute h\u00e4matologische Abkl\u00e4rung f\u00fchrte schlie\u00dflich zur Diagnose einer Polycythaemia vera. Die Assoziation von myeloproliferativen Syndromen mit splanchnischen Venenthrombosen ist gut bekannt und mu\u00df immer gesucht werden. <\/jats:p>","DOI":"10.1024\/0040-5930.56.9.505","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:20:10Z","timestamp":1138710010000},"page":"505-508","source":"Crossref","is-referenced-by-count":2,"title":["Case 9: Splanchnic vein thrombosis as the initial manifestation of polycythemia vera in a 26-year-old woman"],"prefix":"10.1024","volume":"56","author":[{"family":"Escher","sequence":"first","affiliation":[{"name":"H\u00e4matologisches Zentrallabor der Universit\u00e4t, Inselspital, Bern"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Demarmels Biasiutti","sequence":"additional","affiliation":[{"name":"H\u00e4matologisches Zentrallabor der Universit\u00e4t, Inselspital, Bern"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930.56.9.505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:44:34Z","timestamp":1652006674000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930.56.9.505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1999,9,1]]}},"alternative-id":["10.1024\/0040-5930.56.9.505"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930.56.9.505","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,9,1]]}}}