{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T17:18:58Z","timestamp":1694625538471},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2002,5,1]]},"abstract":"<jats:p> Hypertrichose und Hirsutismus verursachen bei betroffenen Frauen erhebliche psychologische Probleme. Gegen den unerw\u00fcnschten Haarwuchs stehen eine Reihe von Therapiem\u00f6glichkeiten zur Verf\u00fcgung, sowohl kosmetischer als auch medizinischer Art. Systemisch werden bei Hirsutismus Antiandrogene eingesetzt, insbesondere von Gyn\u00e4kologen. Seit vielen Jahren etablierte Enthaarungsverfahren sind Zug, Rasur, chemische Depilation mit Thioglykolaten, Elektrolyse und Thermolyse. Ein neues medikament\u00f6ses Verfahren ist die tempor\u00e4re Depilation mit Eflornithin-Creme. Dabei wird im Haarfollikel das Enzym Ornithindekarboxylase gehemmt. Gro\u00dfe Hoffnungen zur permanenten Enthaarung werden in die Photothermolyse mittels Laser oder Blitzlampe gesetzt. <\/jats:p>","DOI":"10.1024\/0040-5930.59.5.251","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:22:16Z","timestamp":1138710136000},"page":"251-255","source":"Crossref","is-referenced-by-count":0,"title":["Hypertrichosis and hirsutism"],"prefix":"10.1024","volume":"59","author":[{"family":"Wolff","sequence":"first","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie, Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Kunte","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie, Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930.59.5.251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:41:44Z","timestamp":1652006504000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930.59.5.251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5,1]]}},"alternative-id":["10.1024\/0040-5930.59.5.251"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930.59.5.251","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,5,1]]}}}