{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T14:37:33Z","timestamp":1725460653816},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2003,1,1]]},"abstract":"<jats:p> In der Akutphase des Hirninfarkts ist die Acetylsalicyls\u00e4ure (ASS) meistens die Therapie der Wahl, wenn keine Thrombolyse in Frage kommt. Eine Ausnahme bilden Patienten mit Hirnvenenthrombosen, Gef\u00e4\u00dfdissektionen sowie kardiogenen Embolien mit sehr hohem Rezidivrisiko, die schon in der Akutphase heparinisiert werden. In der Sekund\u00e4rpr\u00e4vention bei nicht kardioembolisch bedingten Insulten werden Thrombozytenaggregationshemmer eingesetzt: entweder ASS oder ASS\/Dipyridamol oder Clopidogrel bei Patienten mit Hochrisikoprofil oder nach Rezidivinfarkt. In der Sekund\u00e4rpr\u00e4vention wird die orale Antikoagulation bei kardiogenen Embolien, insbesondere beim Vorhofflimmern, bei Hirnvenenthrombosen und beim Antiphospholipid-Antik\u00f6rper- Syndrom eingesetzt. Weniger gut belegte m\u00f6gliche Indikationen sind intrakranielle Gef\u00e4\u00dfstenosen, gro\u00dfe Aortenbogenplaques, Gef\u00e4\u00dfdissektionen sowie ein offenes Foramen ovale. <\/jats:p>","DOI":"10.1024\/0040-5930.60.1.33","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:22:39Z","timestamp":1138710159000},"page":"33-35","source":"Crossref","is-referenced-by-count":2,"title":["Antiplatelet agents and anticoagulation in the neurological patient"],"prefix":"10.1024","volume":"60","author":[{"family":"Arnold","sequence":"first","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik und Poliklinik, Inselspital, Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Nedeltchev","sequence":"additional","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik und Poliklinik, Inselspital, Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Mattle","sequence":"additional","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik und Poliklinik, Inselspital, Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930.60.1.33","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:45:58Z","timestamp":1652006758000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930.60.1.33"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1,1]]}},"alternative-id":["10.1024\/0040-5930.60.1.33"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930.60.1.33","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}