{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T17:19:09Z","timestamp":1694625549452},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2003,9,1]]},"abstract":"<jats:p> Das Schlaganfallrisiko kann durch \u00c4nderung der Lebensgewohnheiten (Ern\u00e4hrung, k\u00f6rperliche Aktivit\u00e4t, Nikotinabstinenz) und die Behandlung der vaskul\u00e4ren Risikofaktoren deutlich reduziert werden. Eine orale Antikoagulation wird bei kardiogenen Embolien, zerebralen Venenthrombosen und beim Antiphospholipid-Antik\u00f6rper-Syndrom eingesetzt. Weniger gut belegte Indikationen sind gro\u00dfe Aortenbogenplaques, Gef\u00e4\u00dfdissektionen und symptomatische intrakranielle Gef\u00e4\u00dfstenosen. Falls keine Indikation f\u00fcr eine Antikoagulation besteht, werden Thrombozytenaggregationshemmer verabreicht. Dabei sind Aspirin oder die Kombination Aspirin-Dipyridamol die Therapie der Wahl. Bei Isch\u00e4mierezidiven unter Aspirin, Aspirinunvertr\u00e4glichkeit oder Hochrisikopatienten wird Clopidogrel verwendet. Bei hochgradigen symptomatischen extrakraniellen Karotisstenosen ist die Indikation zur Karotisendarterektomie unbestritten. <\/jats:p>","DOI":"10.1024\/0040-5930.60.9.521","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:23:06Z","timestamp":1138710186000},"page":"521-526","source":"Crossref","is-referenced-by-count":1,"title":["Schlaganfallpr\u00e4vention"],"prefix":"10.1024","volume":"60","author":[{"given":"M.","family":"Arnold","sequence":"first","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nedeltchev","sequence":"additional","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik Bern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ph.","family":"Lyrer","sequence":"additional","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.W.","family":"Baumgartner","sequence":"additional","affiliation":[{"name":"Neurologische Universit\u00e4tsklinik Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930.60.9.521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:47:36Z","timestamp":1652006856000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930.60.9.521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2003,9,1]]}},"alternative-id":["10.1024\/0040-5930.60.9.521"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930.60.9.521","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,9,1]]}}}