{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:32:16Z","timestamp":1759991536711},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2005,11,1]]},"abstract":"<jats:p> Die Verschiedenartigkeit der in Europa vorkommenden Borrelien, zusammengefasst als Borrelia burgdorferi sensu lato, erlaubt nicht, die f\u00fcr Borrelia burgdorferi sensu stricto in USA etablierten Definitionen und Tests ohne weiteres zu \u00fcbernehmen. Durch die Erweiterung um Antigene der in Europa zus\u00e4tzlich vorkommenden Subspezies B. afzelii und B. garinii bleibt der Nachweis der Borrelien-spezifischen Antik\u00f6rper weiterhin der wichtigste Test in der Borrelien-Diagnostik: Screening mittels ELISA, Best\u00e4tigung durch Immunoblot. Der Erregernachweis mittels PCR oder, in spezialisierten Labors auch mittels Kultur, spielt trotz der hohen Spezifit\u00e4t wegen der tiefen Sensitivit\u00e4t nur eine untergeordnete Rolle. Unver\u00e4ndert gilt, dass Expositionsrisiko, Stadium und klinischer Verlauf die Wahl und Interpretation der diagnostischen Tests bestimmen. <\/jats:p>","DOI":"10.1024\/0040-5930.62.11.737","type":"journal-article","created":{"date-parts":[[2006,1,31]],"date-time":"2006-01-31T12:24:28Z","timestamp":1138710268000},"page":"737-744","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostik der Lyme-Borreliose"],"prefix":"10.1024","volume":"62","author":[{"family":"Steffen","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Medizinische Mikrobiologie, Universit\u00e4t Basel, Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Hirsch","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Infektiologie, Universit\u00e4t Basel, Basel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930.62.11.737","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:38:24Z","timestamp":1652006304000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930.62.11.737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,1]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005,11,1]]}},"alternative-id":["10.1024\/0040-5930.62.11.737"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930.62.11.737","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,1]]}}}