{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T02:27:18Z","timestamp":1767666438000},"reference-count":0,"publisher":"Hogrefe Publishing Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Therapeutische Umschau"],"published-print":{"date-parts":[[2008,4,1]]},"abstract":"<jats:p> Die Hormontherapie (HT) in Peri- und Postmenopause mit \u00d6strogenen und Gestagenen ist mit einem erh\u00f6hten Mammakarzinomrisiko assoziiert. Hormone spielen eine wichtige Rolle im Entstehungsprozess dieser malignen Erkrankung. F\u00fcr das Risiko, ein Mammakarzinom zu entwickeln, haben reproduktive Faktoren einen relevanten Einfluss. Die Anwendung von Sexualsteroiden im Rahmen einer HT stellt einen potentiellen Risikofaktor dar. Zu der Fragestellung wurden in den letzten Jahren eine Reihe von Beobachtungs- und randomisierten Studien publiziert. Diese \u00dcbersicht gibt einen \u00dcberblick der derzeitigen Datenlage zu diesem Thema. <\/jats:p>","DOI":"10.1024\/0040-5930.65.4.231","type":"journal-article","created":{"date-parts":[[2008,3,28]],"date-time":"2008-03-28T03:30:25Z","timestamp":1206675025000},"page":"231-234","source":"Crossref","is-referenced-by-count":0,"title":["Hormontherapie in der Peri- und Postmenopause und Mammakarzinom-Risiko"],"prefix":"10.1024","volume":"65","author":[{"given":"Stefan","family":"Buchholz","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Frauenheilkunde und Geburtshilfe der Universit\u00e4t Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicitas","family":"Horn","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Frauenheilkunde und Geburtshilfe der Universit\u00e4t Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Ortmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Frauenheilkunde und Geburtshilfe der Universit\u00e4t Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"101","container-title":["Therapeutische Umschau"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0040-5930.65.4.231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,8]],"date-time":"2022-05-08T10:33:50Z","timestamp":1652006030000},"score":1,"resource":{"primary":{"URL":"https:\/\/econtent.hogrefe.com\/doi\/10.1024\/0040-5930.65.4.231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4,1]]}},"alternative-id":["10.1024\/0040-5930.65.4.231"],"URL":"https:\/\/doi.org\/10.1024\/0040-5930.65.4.231","relation":{},"ISSN":["0040-5930","1664-2864"],"issn-type":[{"value":"0040-5930","type":"print"},{"value":"1664-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,1]]}}}