{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:24:35Z","timestamp":1765758275732},"reference-count":0,"publisher":"IMR Press","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[2010,4,1]]},"abstract":"<jats:p> Objective: To assess the prevalence of folate, vitamin B<jats:sub>12<\/jats:sub>, and iron deficiencies and their associations with anemia among women of childbearing age in northern China, an area with a reported high incidence of neural tube defects. Methods: Plasma folate, vitamin B<jats:sub>12<\/jats:sub>, ferritin, and hemoglobin levels were measured among 1,671 non-pregnant women of childbearing age from Xianghe County, Hebei Province, China in June 2004. Results: Geometric means [95 % confidence interval (CI)] of plasma concentrations were 9.3 (4.0, 21.6) nmol\/L for folate, 213.1 (82.4, 550.9) pmol\/L for vitamin B<jats:sub>12<\/jats:sub>, 17.4 (1.1, 278.6) \u00b5g\/L for ferritin, and 129.9 (104.6, 161.4) g\/L for hemoglobin (Hb). Approximately 24 % of women had biochemical evidence of folate deficiency (&lt;6.8 nmol\/L), 21.4 % were deficient (&lt;148 pmol\/L) in vitamin B<jats:sub>12<\/jats:sub>, 30.2 % had iron depletion (&lt;15 \u03bcg\/L), and anemia (Hb &lt; 120 g\/L) was detected among 15.4 % of women. Of the three nutrients, only iron depletion (ferritin &lt; 15 \u03bcg\/L) was independently associated with anemia (adjusted odds ratio = 6.4, 95 % CI 4.8, 8.6). Conclusions: Although there were substantial proportions of folate and vitamin B<jats:sub>12<\/jats:sub> deficiencies among women of childbearing age in northern China, iron deficiency was the most important contributor to anemia. <\/jats:p>","DOI":"10.1024\/0300-9831\/a000014","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T02:32:16Z","timestamp":1282876336000},"page":"144-154","source":"Crossref","is-referenced-by-count":5,"title":["Iron, Folate, and B<sub>12<\/sub> Deficiencies and their Associations with Anemia among Women of Childbearing Age in a Rural Area in Northern China"],"prefix":"10.31083","volume":"80","author":[{"given":"Jiang Hui","family":"Zhu","sequence":"first","affiliation":[{"name":"From National Reference Laboratory on Reproductive and Child Health, Ministry of Health and National Center for Maternal and Child Health, Peking University Health Science Center, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale J.","family":"Hu","sequence":"additional","affiliation":[{"name":"National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Hao","sequence":"additional","affiliation":[{"name":"From National Reference Laboratory on Reproductive and Child Health, Ministry of Health and National Center for Maternal and Child Health, Peking University Health Science Center, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao Lan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Maternal and Child Health Institute, Xianghe County, Hebei Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary E.","family":"Cogswell","sequence":"additional","affiliation":[{"name":"National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn B.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Food Science and Human Nutrition Department, University of Florida, Gainesville, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhu","family":"Li","sequence":"additional","affiliation":[{"name":"From National Reference Laboratory on Reproductive and Child Health, Ministry of Health and National Center for Maternal and Child Health, Peking University Health Science Center, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Berry","sequence":"additional","affiliation":[{"name":"National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","container-title":["International Journal for Vitamin and Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0300-9831\/a000014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:10:48Z","timestamp":1723169448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/IJVNR\/80\/2\/10.1024\/0300-9831\/a000014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4,1]]}},"alternative-id":["10.1024\/0300-9831\/a000014"],"URL":"https:\/\/doi.org\/10.1024\/0300-9831\/a000014","relation":{},"ISSN":["0300-9831","1664-2821"],"issn-type":[{"type":"print","value":"0300-9831"},{"type":"electronic","value":"1664-2821"}],"subject":[],"published":{"date-parts":[[2010,4,1]]}}}