{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:42:18Z","timestamp":1773272538724,"version":"3.50.1"},"reference-count":0,"publisher":"IMR Press","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Vitamin and Nutrition Research"],"published-print":{"date-parts":[[2010,12,1]]},"abstract":"<jats:p> The interrelationships between plasma beta-carotene, alpha-tocopherol, and the level of systemic inflammation and oxidative stress were investigated in patients with advanced coronary artery disease (CAD). Plasma beta-carotene, alpha-tocopherol, malondialdehyde, free radicals, interleukin-6, high sensitive C-reactive protein levels, and other risk factors of CAD were determined in a group of patients with advanced CAD [significant stenosis according to coronarographic examination (n = 91) and a control group of examined patients with coronary arteries with no stenosis (n = 49)]. Between-group differences in continuous variables were analyzed with the Hotelling T<jats:sup>2<\/jats:sup>-test (software NCSS2000), analyses of correlation matrix with the software STATISTICA. Advanced CAD coincided with significantly lower plasma concentrations of high-density lipoprotein (HDL)-cholesterol and beta-carotene as well as with elevated levels of all inflammatory markers, but only with mild increase of oxidative stress. Beta-carotene significantly inversely correlated with interleukin-6. This inverse correlation could suggest potential protective effect of beta-carotene on atherosclerosis due to the inhibition of inflammatory processes. <\/jats:p>","DOI":"10.1024\/0300-9831\/a000024","type":"journal-article","created":{"date-parts":[[2013,2,2]],"date-time":"2013-02-02T02:23:04Z","timestamp":1359771784000},"page":"369-377","source":"Crossref","is-referenced-by-count":16,"title":["Inverse Correlation Between Plasma Beta-Carotene and Interleukin-6 in Patients with Advanced Coronary Artery Disease"],"prefix":"10.31083","volume":"80","author":[{"given":"Vladim\u00edra","family":"Muz\u00e1kov\u00e1","sequence":"first","affiliation":[{"name":"Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Kand\u0092\u00e1r","sequence":"additional","affiliation":[{"name":"Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan","family":"Meloun","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jir\u00ed","family":"Skalick\u00fd","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry and Diagnostics, Regional Hospital of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karel","family":"Kr\u00e1lovec","sequence":"additional","affiliation":[{"name":"Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavla","family":"Z\u00e1kov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Vojt\u00edsek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Regional Hospital of Pardubice, Pardubice, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","container-title":["International Journal for Vitamin and Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/econtent.hogrefe.com\/doi\/pdf\/10.1024\/0300-9831\/a000024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T02:10:37Z","timestamp":1723169437000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/IJVNR\/80\/6\/10.1024\/0300-9831\/a000024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,12,1]]}},"alternative-id":["10.1024\/0300-9831\/a000024"],"URL":"https:\/\/doi.org\/10.1024\/0300-9831\/a000024","relation":{},"ISSN":["0300-9831","1664-2821"],"issn-type":[{"value":"0300-9831","type":"print"},{"value":"1664-2821","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,1]]}}}